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1. 发明授权

US06929730B2 Two dimensional microfluidic gene scanner 失效
标题翻译：二维微流体基因扫描仪
公开(公告)号：US06929730B2
公开(公告)日：2005-08-16
申请号：US10135385
申请日：2002-05-01
申请人： Cheng Sheng Lee , Donald Lad DeVoe
发明人： Cheng Sheng Lee , Donald Lad DeVoe
IPC分类号： B01L3/00 , B01L7/00 , B81B1/00 , G01N27/447 , G01N27/453
CPC分类号： G01N27/44773 , B01L3/5027 , B01L7/54 , G01N27/44791
摘要： One embodiment of the invention relates to a microfluidic apparatus for performing two dimensional biomolecular separations. According to one aspect of the invention, after a first dimension separation in a first microchannel, the sample material is electrokinetically and simultaneously transferred to an array of microchannels in the second dimension (e.g., by changing the electric potentials at the reservoirs connected to the microchannels). Preferably any separation accomplished in the first dimension is completely retained upon transfer to the second dimension. According to another aspect of the invention, the separation in the second dimension is performed using a temperature gradient (e.g., a spatial or temporal temperature gradient). According to one embodiment of the invention, the biomolecular material comprises DNA and the first dimension separation is a sized-based separation and the second dimension separation is a sequence-based separation.
摘要翻译：本发明的一个实施方案涉及用于进行二维生物分子分离的微流体装置。根据本发明的一个方面，在第一微通道中的第一维分离之后，将样品材料电动地同时转移到第二维度中的微通道阵列（例如，通过改变连接到微通道的储存器的电位）。优选地，在第一维度上完成的任何分离在转移到第二维度时完全保留。根据本发明的另一方面，使用温度梯度（例如，空间或时间温度梯度）来执行第二维度中的分离。根据本发明的一个实施方案，生物分子材料包含DNA，第一维分离是基于大小的分离，第二维分离是基于序列的分离。

2. 发明申请

US20100135012A1 LED lighting fixture 有权
标题翻译： LED照明灯具
公开(公告)号：US20100135012A1
公开(公告)日：2010-06-03
申请号：US11976449
申请日：2007-10-24
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21V1/00
CPC分类号： F21V13/04 , F21V7/0016 , F21V33/0012 , F21V33/006 , F21Y2105/00 , F21Y2115/10 , G02B6/0021 , G02B6/0046
摘要： A LED lighting fixture includes a light guide board, which is made of a high transmissive material and directly mounted in the cavity of a lamp holder, furniture, utensil, or the construction of a building, having a clear base layer at the front side and a continuous piece of reflective layer with a corrugated cross section at the back side, and a plurality of LEDs mounted within the cavity outside the light guide board and controlled to emit light transversely into the inside of the light guide boards for reflection by the reflective layer to increase the angle of illumination and to provide a uniform lighting effect having an enhanced brightness without multi-image and flashing.
摘要翻译： LED照明灯具包括导光板，该导光板由高透射材料制成并直接安装在灯架的腔体中，家具，器具或建筑物的结构，其前侧具有透明的基底层，在背面具有波纹状横截面的连续的反射层片，以及安装在导光板外部的空腔内的多个LED，被控制成横向地向导光板的内部发射光，以反射层以增加照明角度并且提供具有增强的亮度的均匀的照明效果，而不需要多图像和闪光。

3. 发明授权

US07641780B2 Two-dimensional microfluidics for protein separations and gene analysis 失效
标题翻译：用于蛋白质分离和基因分析的二维微流体
公开(公告)号：US07641780B2
公开(公告)日：2010-01-05
申请号：US11086400
申请日：2005-03-23
申请人： Cheng Sheng Lee , Don DeVoe
发明人： Cheng Sheng Lee , Don DeVoe
IPC分类号： G01N27/453 , G01N30/02 , B01L3/00
CPC分类号： C07K1/26 , C07K1/285
摘要： The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins, DNA and other biomolecules. According to another aspect of the invention, an array of tertiary microchannels extending in a third direction may be utilized.
摘要翻译：本发明提供了用于进行2-D生物分子分离的微流体装置。微流体2-D器件可以包括第一和第二平面衬底，其包括至少第一维度微通道，其沿第一方向延伸，并且第二维微通道阵列沿第二方向延伸，优选地与第一维度正交。至少一些微通道的端部与多个储存器流体连通。基板还可以包括多个微通道和储存器。储存器与多个电极和电压电源电连通。该装置能够对蛋白质，DNA和其他生物分子进行二维分离。根据本发明的另一方面，可以利用沿第三方向延伸的三级微通道阵列。

4. 发明申请

US20080158911A1 Light-guide board 失效
公开(公告)号：US20080158911A1
公开(公告)日：2008-07-03
申请号：US11648607
申请日：2007-01-03
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21V7/04
CPC分类号： G02B6/0033 , G02B6/0055
摘要： A light-guide board includes a light guide plate made out of an optically transmissive material and having a transparent layer and a back reflecting layer formed integral with the back side of the transparent layer, and a plurality of reflecting baffles respectively extending from the back reflecting layer and embedded in the transparent layer for reflecting light to enhance the intensity of light and the uniformity in light intensity.

5. 发明授权

US06974526B2 Plastic microfluidics enabling two-dimensional protein separations in proteome analysis 失效
标题翻译：塑料微流体使蛋白质组分析中的二维蛋白质分离
公开(公告)号：US06974526B2
公开(公告)日：2005-12-13
申请号：US10135386
申请日：2002-05-01
申请人： Cheng Sheng Lee , Don DeVoe
发明人： Cheng Sheng Lee , Don DeVoe
IPC分类号： B81B1/00 , G01N27/447 , G01N27/453
CPC分类号： G01N27/44795 , G01N27/44773 , G01N27/44791
摘要： The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins and other biomolecules. According to another aspect of the invention, an isoelectric point based separation is enabled in a first dimension, and a size based separation in a second dimension.
摘要翻译：本发明提供了用于进行2-D生物分子分离的微流体装置。微流体2-D器件可以包括第一和第二平面衬底，其包括至少第一维度微通道，其沿第一方向延伸，并且第二维微通道阵列沿第二方向延伸，优选地与第一维度正交。至少一些微通道的端部与多个储存器流体连通。基板还可以包括多个微通道和储存器。储存器与多个电极和电压电源电连通。该装置能够进行蛋白质和其他生物分子的二维分离。根据本发明的另一方面，基于等电点的分离在第一维度和基于尺寸的第二维度的分离中得以实现。

6. 发明授权

US07963689B2 LED-edgelit light guide fixture having LED receiving grooves 有权
标题翻译：具有LED接收槽的LED-edgelit导光固定装置
公开(公告)号：US07963689B2
公开(公告)日：2011-06-21
申请号：US11976449
申请日：2007-10-24
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21V7/09 , F21V7/22
CPC分类号： F21V13/04 , F21V7/0016 , F21V33/0012 , F21V33/006 , F21Y2105/00 , F21Y2115/10 , G02B6/0021 , G02B6/0046
摘要： A LED lighting fixture includes a cavity receiving a light guide board, and a plurality of LEDs mounted within two reinforcing parallel grooves formed in the light guide board along the length of corresponding opposite lateral sides. The light guide board further includes a clear base portion made of a light transmissive material, and a continuous reflective layer disposed over a surface of the clear base portion, the reflective layer having a portion protruding into the clear base portion. Light from the LEDs is injected transversely into the inside of the light guide board for reflection by the reflective layer to be ejected from the lighting fixture through a surface of the light guide board.
摘要翻译： LED照明灯具包括容纳导光板的空腔，以及安装在沿着相应的相对侧面的长度形成在导光板中的两个加强平行凹槽内的多个LED。导光板还包括由透光材料制成的透明基部和设置在透明基部的表面上的连续反射层，所述反射层具有突出到透明基部的部分。来自LED的光横向地注入导光板的内部，用于通过反射层反射，以从照明器材通过导光板的表面喷射。

7. 发明授权

US07806581B2 Lighting lamp 有权
公开(公告)号：US07806581B2
公开(公告)日：2010-10-05
申请号：US12000194
申请日：2007-12-10
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21V7/04
CPC分类号： F21S8/04 , F21Y2105/00 , F21Y2115/10 , G02B6/0046
摘要： A lighting lamp includes a light guide board, which is directly mounted in the cavity of a lamp holder, furniture, utensil, or the construction of a building, having a clear transmissive layer at the front side and a continuous piece of reflective layer a clear transmission layer at the front side and a reflective layer at the back side that has the shape of an umbrella surface and sloping from the periphery toward its center, and a plurality of LEDs mounted within the cavity outside the light guide board and controlled to emit light laterally into the inside of the light guide boards to provide a uniform lighting effect having an enhanced brightness without multi-image and to simulate the lighting effect of a ball lamp.

8. 发明申请

US20100214771A1 Lighting lamp 有权
标题翻译：照明灯
公开(公告)号：US20100214771A1
公开(公告)日：2010-08-26
申请号：US12000194
申请日：2007-12-10
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21S8/04 , F21V1/00
CPC分类号： F21S8/04 , F21Y2105/00 , F21Y2115/10 , G02B6/0046
摘要： A lighting lamp includes a light guide board, which is directly mounted in the cavity of a lamp holder, furniture, utensil, or the construction of a building, having a clear transmissive layer at the front side and a continuous piece of reflective layer a clear transmission layer at the front side and a reflective layer at the back side that has the shape of an umbrella surface and sloping from the periphery toward its center, and a plurality of LEDs mounted within the cavity outside the light guide board and controlled to emit light laterally into the inside of the light guide boards to provide a uniform lighting effect having an enhanced brightness without multi-image and to simulate the lighting effect of a ball lamp.
摘要翻译：照明灯包括直接安装在灯座的空腔中的导光板，家具，器具或建筑物的结构，其在前侧具有透明透明层，并且连续的反射层片段清晰前侧的透光层和背面侧的反射层，其具有伞面的形状并且从周边向其中心倾斜;以及多个LED，其安装在导光板外部的空腔内并被控制发光横向进入导光板的内部，以提供均匀的照明效果，具有增强的亮度而不具有多图像并且模拟球形灯的照明效果。

9. 发明授权

US07470054B2 Light-guide board 失效
标题翻译：导光板
公开(公告)号：US07470054B2
公开(公告)日：2008-12-30
申请号：US11648607
申请日：2007-01-03
申请人： Cheng Sheng Lee
发明人： Cheng Sheng Lee
IPC分类号： F21V8/00 , F21V7/00
CPC分类号： G02B6/0033 , G02B6/0055
摘要： A light-guide board includes a light guide plate made out of an optically transmissive material and having a transparent layer and a back reflecting layer formed integral with the back side of the transparent layer, and a plurality of reflecting baffles respectively extending from the back reflecting layer and embedded in the transparent layer for reflecting light to enhance the intensity of light and the uniformity in light intensity.
摘要翻译：导光板包括由透光材料制成并具有与透明层的背面一体形成的透明层和背反射层的导光板，以及分别从背反射层延伸的多个反射挡板层并嵌入在透明层中以反射光以增强光的强度和光强度的均匀性。

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