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1. 发明申请

US20100286684A1 IRRIGATED ABLATION CATHETER WITH MULTIPLE SEGMENTED ABLATION ELECTRODES 审中-公开
标题翻译：具有多个SEGMENTED ABLATION电极的雷射吸管
公开(公告)号：US20100286684A1
公开(公告)日：2010-11-11
申请号：US12436977
申请日：2009-05-07
申请人： Cary HATA , Thu Xuan Tran , Alan de la Rama , Tho Hoang Nguyen , Irvin John Narciso , Peter C. Chen , Hanh Ngoc Do
发明人： Cary HATA , Thu Xuan Tran , Alan de la Rama , Tho Hoang Nguyen , Irvin John Narciso , Peter C. Chen , Hanh Ngoc Do
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2018/00029 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00839 , A61B2018/1467 , A61B2218/002 , C08L2201/12
摘要： In one embodiment, an irrigated catheter ablation apparatus comprises an elongated body having a distal end, a proximal end, and at least one fluid lumen extending longitudinally therein; and a plurality of segmented ablation electrodes on a distal portion of the elongated body. The electrodes are spaced from the proximal end and from the distal end of the elongated body by electrically nonconductive segments. The electrodes are spaced from each other longitudinally by electrically nonconductive segments. For each electrode that is longitudinally disposed next to one of the nonconductive segments, an edge is formed between an electrode end of the electrode and a nonconductive segment end of the nonconductive segment. A plurality of elution holes are disposed adjacent to the edges. A plurality of ducts establish fluid communication between the elution holes and the fluid lumen.
摘要翻译：在一个实施例中，灌溉导管消融装置包括细长体，其具有远端，近端和在其中纵向延伸的至少一个流体腔; 以及在所述细长体的远侧部分上的多个分段的消融电极。电极通过非导电段与细长主体的近端和远端隔开。电极通过非导电段纵向间隔开。对于纵向设置在非导电段之一处的每个电极，在电极的电极端和非导电段的非导电段端之间形成边缘。多个洗脱孔与边缘相邻设置。多个管道在洗脱孔和流体腔之间建立流体连通。

2. 发明授权

US08974446B2 Ultrasound ablation apparatus with discrete staggered ablation zones 有权
标题翻译：具有离散交错消融区域的超声消融装置
公开(公告)号：US08974446B2
公开(公告)日：2015-03-10
申请号：US13019563
申请日：2011-02-02
申请人： Tho Hoang Nguyen , Cary Hata , Alan De La Rama , Vivian Tran , Peter C. Chen
发明人： Tho Hoang Nguyen , Cary Hata , Alan De La Rama , Vivian Tran , Peter C. Chen
IPC分类号： A61B18/04 , A61B17/22 , A61N7/02 , A61B5/01 , A61B5/0402 , A61B5/00 , A61B17/00 , A61B17/32 , A61B18/00 , A61N7/00
CPC分类号： A61B17/2202 , A61B5/01 , A61B5/0402 , A61B5/6852 , A61B2017/00243 , A61B2017/00247 , A61B2017/22021 , A61B2017/320084 , A61B2018/00392 , A61N7/022 , A61N2007/003 , A61N2007/0078
摘要： An ablation apparatus comprises an ultrasonic transducer which includes a piezoelectric element having a cylindrical shape; a plurality of external electrodes disposed on the outer surface of the piezoelectric element; and at least one internal electrode disposed on the inner surface of the piezoelectric element. The at least one internal electrode provides corresponding internal electrode portions that are disposed opposite the external electrodes with respect to the piezoelectric element, the external electrodes and the at least one internal electrode to be energized to apply an electric field across the piezoelectric element. The ultrasonic ablation zones of the external electrodes are distributed in a staggered configuration so as to span one or more open arc segments around the longitudinal axis, and the ultrasound ablation zones of all external electrodes projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis.
摘要翻译：消融装置包括：超声波换能器，其包括具有圆筒形状的压电元件; 设置在所述压电元件的外表面上的多个外部电极; 以及设置在压电元件的内表面上的至少一个内部电极。所述至少一个内部电极相对于所述压电元件，所述外部电极和所述至少一个内部电极与所述外部电极相对设置相应的内部电极部分，以在所述压电元件上施加电场。外部电极的超声波消融区域以交错的构型分布，以跨越纵向轴线的一个或多个开放弧段，并且所有外部电极的超声消融区域纵向投影到垂直于纵向的任何横向平面轴线围绕纵向轴线跨越基本上闭合的环路。

3. 发明申请

US20080177205A1 Non-contact tissue ablation device and methods thereof 审中-公开
标题翻译：非接触组织消融装置及其方法
公开(公告)号：US20080177205A1
公开(公告)日：2008-07-24
申请号：US11975822
申请日：2007-10-22
申请人： Alan de la Rama , Tho Hoang Nguyen , Vivian Tran , Cary K. Hata , Peter C. Chen
发明人： Alan de la Rama , Tho Hoang Nguyen , Vivian Tran , Cary K. Hata , Peter C. Chen
IPC分类号： A61N7/02
CPC分类号： A61B17/2202 , A61B5/01 , A61B5/0245 , A61B5/04001 , A61B2017/00243 , A61B2017/00247 , A61B2017/320084 , A61B2018/00392 , A61N7/022
摘要： A catheter for ablating body tissue of the interior regions of the heart includes a handle assembly, a shaft, and a distal tip section coupled to the distal end of the shaft. The distal tip section has a non-compliant and non-porous cap that has a tubular wall that defines a bore, and an ablation element that is housed inside the bore and spaced apart from the wall of the cap.
摘要翻译：用于消除心脏内部区域的身体组织的导管包括手柄组件，轴和联接到轴的远端的远侧末端部分。远侧末端部分具有非顺应性和无孔的帽，其具有限定孔的管状壁和容纳在孔内并与盖的壁间隔开的消融元件。

4. 发明授权

US07285116B2 Non-contact tissue ablation device and methods thereof 有权
标题翻译：非接触组织消融装置及其方法
公开(公告)号：US07285116B2
公开(公告)日：2007-10-23
申请号：US10845798
申请日：2004-05-15
申请人： Alan de la Rama , Tho Hoang Nguyen , Vivian Tran , Cary K. Hata , Peter C Chen
发明人： Alan de la Rama , Tho Hoang Nguyen , Vivian Tran , Cary K. Hata , Peter C Chen
IPC分类号： A61B18/14
CPC分类号： A61B17/2202 , A61B5/01 , A61B5/0245 , A61B5/04001 , A61B2017/00243 , A61B2017/00247 , A61B2017/320084 , A61B2018/00392 , A61N7/022
摘要： A catheter for ablating body tissue of the interior regions of the heart includes a handle assembly, a shaft, and a distal tip section coupled to the distal end of the shaft. The distal tip section has a non-compliant and non-porous cap that has a tubular wall that defines a bore, and an ablation element that is housed inside the bore and spaced apart from the wall of the cap.
摘要翻译：用于消除心脏内部区域的身体组织的导管包括手柄组件，轴和联接到轴的远端的远侧末端部分。远侧末端部分具有非顺应性和无孔的帽，其具有限定孔的管状壁和容纳在孔内并与盖的壁间隔开的消融元件。

5. 发明授权

US5954719A System for operating a RF ablation generator 失效
标题翻译：用于操作RF消融发生器的系统
公开(公告)号：US5954719A
公开(公告)日：1999-09-21
申请号：US46237
申请日：1998-03-23
申请人： Peter Cheng Chen , Tho Hoang Nguyen
发明人： Peter Cheng Chen , Tho Hoang Nguyen
IPC分类号： A61B18/12 , A61B18/14 , A61B17/36
CPC分类号： A61B18/1206 , A61B18/1492 , A61B2017/003 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00839 , A61B2018/0091 , A61B2018/1253 , A61B2018/1467
摘要： A catheter-based system for operating a RF ablation generator comprising a RF splitter for delivering RF energy to a plurality of electrodes; a low-pass filter located between the RF splitter and an external EKG monitor for displaying real-time signal to said EKG monitor; and a software program having temperature data input from a plurality of temperature sensors and signal output capability, wherein the software program sends out signals to the RF splitter being adapted to control the RF energy output to each electrode.
摘要翻译：一种用于操作RF消融发生器的基于导管的系统，包括用于将RF能量传递到多个电极的RF分离器; 位于RF分离器和外部EKG监视器之间的低通滤波器，用于向所述EKG监视器显示实时信号; 以及软件程序，其具有从多个温度传感器输入的温度数据和信号输出能力，其中所述软件程序向所述RF分离器发送适合于控制到每个电极的RF能量输出的信号。

6. 发明授权

US08545409B2 Arrangement and interface for RF ablation system with acoustic feedback 有权
标题翻译：具有声学反馈的RF消融系统的布置和接口
公开(公告)号：US08545409B2
公开(公告)日：2013-10-01
申请号：US13191690
申请日：2011-07-27
申请人： John Sliwa , Tho Hoang Nguyen , Zhenyi Ma , Stephen Morse
发明人： John Sliwa , Tho Hoang Nguyen , Zhenyi Ma , Stephen Morse
IPC分类号： A61B8/00
CPC分类号： A61B8/0858 , A61B8/12 , A61B8/445 , A61B8/5223 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2018/00738 , A61B2034/303 , A61B2090/3784
摘要： A system for ablation with acoustic feedback comprises: a catheter which includes an elongated catheter body; at least one ablation element to ablate a targeted tissue region; and a pulse-echo ultrasonic transducer arranged to emit and receive an acoustic beam along a centroid in a beam direction, at a transducer beam angle of between about 30 degrees and about 60 degrees relative to a distal direction of the longitudinal axis at a location of intersection between the longitudinal axis and the beam direction of the centroid of the acoustic beam of the ultrasonic transducer, wherein the transducer transmits and receives acoustic pulses to provide lesion information in the targeted tissue region; an ablation power subsystem; an ultrasonic transmit and receive subsystem to operate the ultrasonic transducer; a control subsystem to control operation of the ablation power subsystem and the ultrasonic transmit and receive subsystem; and a display.
摘要翻译：一种具有声反馈消融的系统包括：导管，其包括细长的导管体; 至少一个消融元件以消融靶向组织区域; 以及脉冲回波超声波换能器，被布置成沿着波束方向沿着质心发射和接收声束，相对于纵轴的远端方向以约30度至约60度之间的换能器射束角度在所述超声波换能器的声束的心轴的纵轴与所述梁的方向的交点，其中所述换能器发射和接收声脉冲以在所述目标组织区域中提供病变信息; 消融电源子系统; 超声波发射和接收子系统来操作超声波换能器; 用于控制消融电力子系统和超声波发射和接收子系统的操作的控制子系统; 和显示器。

7. 发明授权

US6006123A Electrode catheter system and methods for using same 有权
标题翻译：电极导管系统及其使用方法
公开(公告)号：US6006123A
公开(公告)日：1999-12-21
申请号：US169107
申请日：1998-10-09
申请人： Tho Hoang Nguyen , Hosheng Tu
发明人： Tho Hoang Nguyen , Hosheng Tu
IPC分类号： A61B18/14 , A61N1/05
CPC分类号： A61B18/1492 , A61B18/1233 , A61B2017/003 , A61B2017/00867 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00708 , A61B2018/00791 , A61B2018/00797 , A61B2018/00839 , A61B2018/124 , C08L2201/12
摘要： A method for positioning an electrode catheter system having safety means at its distal section within a heart chamber comprises percutaneously introducing the distal end of a catheter through an artery or vein to the heart chamber. Once the catheter tip is at the desired location, the connector of the handle at the proximal end is connected to an EKG monitor. And the electrical signal from the electrodes on the distal section can be transmitted to the exterior EKG monitor for cardiac mapping. Alternately, the radio frequency current can be supplied to one or more of the electrodes on the distal section once an intimate contact with a tissue is achieved using the catheter of this invention.
摘要翻译：一种在心脏室内的远侧部位具有安全装置的电极导管系统的定位方法包括将导管的远端通过动脉或静脉经皮导入心室。一旦导管尖端处于所需位置，手柄在近端的连接器连接到EKG监视器。并且来自远端部分上的电极的电信号可以传输到外部EKG监测器用于心脏图像。或者，一旦使用本发明的导管实现与组织的紧密接触，则射频电流可被提供给远端部分上的一个或多个电极。

8. 发明授权

US5935063A Electrode catheter system and methods thereof 失效
标题翻译：电极导管系统及其方法
公开(公告)号：US5935063A
公开(公告)日：1999-08-10
申请号：US959813
申请日：1997-10-29
申请人： Tho Hoang Nguyen
发明人： Tho Hoang Nguyen
IPC分类号： A61B18/14 , A61N1/05
CPC分类号： A61B18/1492 , A61B18/1233 , A61B2017/003 , A61B2017/00867 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00708 , A61B2018/00791 , A61B2018/00797 , A61B2018/00839 , A61B2018/124 , C08L2201/12
摘要： An electrode catheter system suitable for electrophysiology mapping and/or radiofrequency ablation of cardiac tissue comprises a catheter shaft having a distal end, a proximal handle, and at least a lumen extending therebetween, wherein a distal section of the shaft is either a fixed curve or deflectable; and safety restricting means at the very distal end of the catheter shaft being provided to maintain the integrity of the catheter by holding the tip electrode in place from thermal cycling effect.
摘要翻译：适用于心脏组织的电生理学测绘和/或射频消融的电极导管系统包括导管轴，其具有远端，近侧手柄和至少在其间延伸的内腔，其中所述轴的远端部分是固定曲线或可偏转的并且设置在导管轴的非常远端处的安全限制装置，以通过将尖端电极保持在适合于热循环效应的位置来保持导管的完整性。

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