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1. 发明授权

US11839391B2 Optical emitter housing assembly for intravascular lithotripsy device 有权
公开(公告)号：US11839391B2
公开(公告)日：2023-12-12
申请号：US17970363
申请日：2022-10-20
申请人： BOLT MEDICAL, INC.
发明人： Eric Schultheis , Alvin Salinas , Alan Duong
IPC分类号： A61B18/20 , A61B17/22 , A61B18/24 , A61B18/00 , A61B18/26
CPC分类号： A61B17/22022 , A61B18/24 , A61B2017/22021 , A61B2017/22025 , A61B2017/22038 , A61B2018/0022 , A61B2018/00404 , A61B2018/263
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) of a blood vessel (108) within a body (107) of a patient (109) includes an energy source (124), a catheter fluid (132), and an emitter assembly (129). The energy source (124) generates energy. The emitter assembly (129) includes (i) at least a portion of an energy guide (122A) having a guide distal end (122D) that is selectively positioned near the treatment site (106), (ii) a plasma generator (133), and (iii) an emitter housing (260) that is secured to each of the energy guide (122A) and the plasma generator (133) to maintain a relative position between the guide distal end (122D) of the energy guide (122A) and the plasma generator (133). The energy guide (122A) is configured to receive energy from the energy source (124) and direct the energy toward the plasma generator (133) to generate a plasma bubble (134) in the catheter fluid (132). The plasma generator (133) directs energy from the plasma bubble (134) toward the treatment site (106).

2. 发明公开

US20230293197A1 LOW PROFILE ELECTRODES FOR A SHOCK WAVE CATHETER 审中-公开
公开(公告)号：US20230293197A1
公开(公告)日：2023-09-21
申请号：US18114882
申请日：2023-02-27
申请人： Shockwave Medical, Inc.
发明人： Hoa D. NGUYEN , KHANH VO
IPC分类号： A61B17/22 , A61B18/14
CPC分类号： A61B17/22022 , A61B17/2202 , A61B18/1492 , A61B2017/22001 , A61B2017/22021 , A61B2017/22025 , A61B2017/22051 , A61B2017/22061 , A61B2017/22062 , A61B2017/22098
摘要： The invention provides a device for generating shock waves. The device may comprise an elongated tube and a conductive sheath circumferentially mounted around the elongated tube. The device may further comprise first and second insulated wires extending along the outer surface of the elongated tube. A portion of the first insulated wire is removed to form a first inner electrode, which is adjacent to a first side edge of the conductive sheath. A portion of the second insulated wire is removed to form a second inner electrode, which is adjacent to a second side edge of the conductive sheath. Responsive to a high voltage being applied across the first inner electrode and the second inner electrode, a first shock wave is created across the first side edge and the first inner electrode, and a second shock wave is created across the second side edge and the second inner electrode.

3. 发明申请

US20170360461A1 ELECTRO-HYDRAULICALLY ACTUATED LITHOTRIPTERS AND RELATED METHODS 审中-公开
公开(公告)号：US20170360461A1
公开(公告)日：2017-12-21
申请号：US15527618
申请日：2015-11-24
申请人： C.R. BARD, INC.
发明人： Michael Dolgin
IPC分类号： A61B17/22
CPC分类号： A61B17/22012 , A61B17/2202 , A61B2017/22021 , A61B2017/22025
摘要： Embodiments are directed to electro-hydraulically actuated lithotripters and methods for fragmenting stones using such lithotripters. In an embodiment, a lithotripter apparatus for fragmenting at least one stone in a body is disclosed. The lithotripter apparatus includes a chamber configured to contain an electro-conductive fluid, which includes a proximal end wall and a distal end wall spaced from the proximal end wall. A chisel is coupled to the chamber and located at least proximate to the distal end wall. A proximal electrode is located at least partially in the chamber. A distal electrode is located at least partially in the chamber and spaced from the proximal electrode. Responsive to an effective voltage applied between the proximal and distal electrodes, the proximal and distal electrodes are configured to electrically discharge into the electro-conductive fluid to generate shock waves in the chamber that accelerate the chisel toward the at least one stone.

4. 发明申请

US20170086849A1 Confinement Of Kidney Stone Fragments During Lithotripsy 审中-公开
公开(公告)号：US20170086849A1
公开(公告)日：2017-03-30
申请号：US15149885
申请日：2016-05-09
申请人： Genzyme Corporation
发明人： Alexander Schwarz , W. Scott McDougal
IPC分类号： A61B17/12 , A61B17/225 , A61B18/26 , A61B17/22
CPC分类号： A61B17/1204 , A61B17/12022 , A61B17/12045 , A61B17/12099 , A61B17/12186 , A61B17/22012 , A61B17/2202 , A61B17/22022 , A61B17/225 , A61B18/26 , A61B2017/12127 , A61B2017/22021 , A61B2017/22025 , A61B2017/22054 , A61B2017/22067 , A61B2017/22082 , A61F2/013 , A61H23/008
摘要： The present invention improves significantly the success rate of lithotripsy and reduces the risk of tissue damage, by injecting a temporary plug in front, and optionally behind a concretion (for extracorporeal lithotripsy) or behind a concretion (for intracorporeal lithotripsy). One aspect of the present invention relates to injecting an inverse thermosensitive polymer solution into a lumen, thereby preventing the migration of a concretion, or its fragments, upon extracorporeal or intracorporeal lithotripsy.

5. 发明授权

US09498237B2 Method and system for destroying of undesirable formations in mammalian body 有权
标题翻译：用于破坏哺乳动物体内不良形成的方法和系统
公开(公告)号：US09498237B2
公开(公告)日：2016-11-22
申请号：US14297982
申请日：2014-06-06
申请人： Lithotech Medical Ltd.
发明人： Valery Diamant , Alexey Dutov , Vladimir Chernenko , Marat Lerner
IPC分类号： A61B17/22 , A61B17/00 , A61B18/00
CPC分类号： A61B17/22022 , A61B17/2202 , A61B90/98 , A61B2017/00185 , A61B2017/00194 , A61B2017/00199 , A61B2017/00477 , A61B2017/22021 , A61B2018/00988 , A61B2090/0803
摘要： A method and a system for destruction of an undesirable formation in a mammalian body are described. The invention is based on inserting a probe into mammalian body; said probe is electrically connectable to a control unit and upon bringing the probe in physical contact with the formation supplying pulses of energy from the control unit to the probe in order to destroy the formation. The invention further comprises counting amount of pulses being supplied to the probe and establishing a remaining service life of the probe by subtracting the amount of pulses being supplied to the probe from an amount of pulses corresponding to initial service life of the probe. The treatment session is automatically terminates as soon as amount of pulses being supplied to the probe approaches at least a fraction of the established remaining service life of the probe. The established remaining service life of the probe is stored for new treatment session. Delivery of pulses automatically terminates when the remaining service life is exhausted and use of such probe becomes impossible.
摘要翻译：描述了用于在哺乳动物体内破坏不良形成的方法和系统。本发明基于将探针插入哺乳动物体内; 所述探针可电连接到控制单元，并且在使探针物理接触地层时，能够从控制单元向探头提供能量的脉冲以破坏地层。本发明还包括计数供给探针的脉冲数量，并且通过从与探针的初始使用寿命相对应的脉冲量减去从探针提供的脉冲量来建立探头的剩余使用寿命。一旦提供给探头的脉冲量接近探测器建立的剩余使用寿命的至少一部分，治疗会话就会自动终止。探针的已建立的剩余使用寿命被存储用于新的治疗期。当剩余使用寿命耗尽并且使用这种探头变得不可能时，脉冲传递将自动终止。

6. 发明申请

US20160331389A1 LOW PROFILE ELECTRODES FOR AN ANGIOPLASTY SHOCK WAVE CATHETER 审中-公开
公开(公告)号：US20160331389A1
公开(公告)日：2016-11-17
申请号：US15220999
申请日：2016-07-27
申请人： SHOCKWAVE MEDICAL, INC.
发明人： Doug HAKALA , John M. ADAMS , Khoi T. LE , Show-Mean Steve WU
IPC分类号： A61B17/22
CPC分类号： A61B17/2202 , A61B17/22022 , A61B2017/22001 , A61B2017/22021 , A61B2017/22025 , A61B2017/22028 , A61B2017/22051 , A61B2017/22062
摘要： Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.

7. 发明授权

US09237898B2 Systems and methods for ultrasound imaging and insonation of microbubbles 有权
标题翻译：用于超声成像和微泡发育的系统和方法
公开(公告)号：US09237898B2
公开(公告)日：2016-01-19
申请号：US13386391
申请日：2010-07-21
申请人： John A. Hossack , Brian R. Wamhoff , Alexander L. Klibanov , Johnny Chen , Brent A. French
发明人： John A. Hossack , Brian R. Wamhoff , Alexander L. Klibanov , Johnny Chen , Brent A. French
IPC分类号： A61B17/22 , A61B8/12 , A61N7/00 , A61B5/00 , A61B6/00 , A61B8/06 , A61B8/08 , A61B8/00 , A61B17/00 , A61B19/00 , A61M25/00 , A61M25/10 , A61M37/00
CPC分类号： A61M37/0092 , A61B5/7285 , A61B6/503 , A61B6/504 , A61B6/541 , A61B8/06 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B8/481 , A61B8/543 , A61B17/22 , A61B17/22004 , A61B17/2202 , A61B2017/00893 , A61B2017/22021 , A61B2017/22054 , A61B2017/22067 , A61B2017/22088 , A61B2017/22089 , A61B2090/3735 , A61B2090/3784 , A61M25/00 , A61M25/0082 , A61M25/10 , A61M37/00 , A61M2025/0073 , A61M2025/1052 , A61N7/00 , A61N2007/0039 , A61N2007/0043
摘要： A catheter system including an elongate tubular member having a proximal end portion, a distal end portion and a lumen extending through at least a portion of a length of the elongate tubular member. The distal end portion of the elongate member is dimensioned and adapted to advance to or in proximity to a treatment site of a subject. A microbubble device is in fluid communication with the lumen. The microbubble device includes at least one input port for receiving a flow of material into the device and an output port configured to output microbubbles from the microbubble device. A second tubular member is in fluid communication with one of the at least one input ports. A pressure fitting arrangement is adapted to maintain a seal between the second tubular member and the input port.
摘要翻译：导管系统，其包括细长管状构件，其具有近端部分，远端部分和延伸穿过细长管状构件的长度的至少一部分的内腔。细长构件的远端部分的尺寸和尺寸适于前进到或接近受试者的治疗部位。微泡装置与内腔流体连通。微泡装置包括至少一个用于接收材料流入装置的输入端口和配置成从微泡装置输出微气泡的输出端口。第二管状构件与所述至少一个输入端口中的一个流体连通。压力配合装置适于在第二管状构件和输入端口之间保持密封。

8. 发明授权

US09138249B2 Shock wave catheter system with arc preconditioning 有权
标题翻译：具有电弧预处理的冲击波导管系统
公开(公告)号：US09138249B2
公开(公告)日：2015-09-22
申请号：US13777807
申请日：2013-02-26
申请人： Shockwave Medical, Inc.
发明人： John Adams , Randy Holmberg
IPC分类号： A61B17/22 , A61B17/225 , F17D3/00 , A61B17/00
CPC分类号： A61B17/225 , A61B17/2202 , A61B17/22022 , A61B2017/00159 , A61B2017/00176 , A61B2017/22021 , A61B2017/22062 , F17D3/00 , G10K15/06 , Y10T137/0391
摘要： A shock wave catheter system and method produces a shock wave with reduced energy. The system includes a catheter and a power source. The catheter has an elongated carrier and a balloon about the carrier in sealed relation thereto. The balloon is arranged to receive a fluid therein that inflates the balloon. The catheter further includes an arc generator including at least two electrodes within the balloon. The power source is coupled to the at least two electrodes and is configured to grow a bubble at one of the at least two electrodes and then thereafter to rapidly expand the bubble to form a shock wave within the balloon.
摘要翻译：冲击波导管系统和方法产生具有降低能量的冲击波。该系统包括导管和电源。导管具有细长的载体和围绕载体与其密封的球囊。气囊被布置成接收其中使气囊膨胀的流体。导管还包括电弧发生器，其包括气囊内的至少两个电极。电源耦合到至少两个电极，并且被配置为在至少两个电极中的一个电极处生长气泡，然后在此之后快速膨胀气泡以在气囊内形成冲击波。

9. 发明授权

US09011462B2 Shockwave balloon catheter system 有权
公开(公告)号：US09011462B2
公开(公告)日：2015-04-21
申请号：US13646570
申请日：2012-10-05
申请人： Shockwave Medical, Inc.
发明人： John M. Adams , Daniel Hawkins
IPC分类号： A61B17/22 , A61B17/225 , A61B17/3207
CPC分类号： A61B17/22022 , A61B17/2202 , A61B17/22029 , A61B17/2251 , A61B17/320725 , A61B2017/22001 , A61B2017/22021 , A61B2017/22024 , A61B2017/22025 , A61B2017/22038 , A61B2017/22058 , A61B2017/22061 , A61B2017/22062
摘要： A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

10. 发明授权

US08998928B2 Confinement of kidney stone fragments during lithotripsy 有权
标题翻译：碎石期间肾结石碎片的限制
公开(公告)号：US08998928B2
公开(公告)日：2015-04-07
申请号：US13779415
申请日：2013-02-27
申请人： Genzyme Corporation
发明人： Alexander Schwarz , W. Scott McDougal
IPC分类号： A61B17/22 , A61B17/225 , A61B17/12 , A61F2/01
CPC分类号： A61B17/1204 , A61B17/12022 , A61B17/12045 , A61B17/12099 , A61B17/12186 , A61B17/22012 , A61B17/2202 , A61B17/22022 , A61B17/225 , A61B18/26 , A61B2017/12127 , A61B2017/22021 , A61B2017/22025 , A61B2017/22054 , A61B2017/22067 , A61B2017/22082 , A61F2/013 , A61H23/008
摘要： The present invention improves significantly the success rate of lithotripsy and reduces the risk of tissue damage, by injecting a temporary plug in front, and optionally behind a concretion (for extracorporeal lithotripsy) or behind a concretion (for intracorporeal lithotripsy). One aspect of the present invention relates to injecting an inverse thermosensitive polymer solution into a lumen, thereby preventing the migration of a concretion, or its fragments, upon extracorporeal or intracorporeal lithotripsy.
摘要翻译：本发明通过在前面注射临时塞子，并且可选地在结石后（用于体外碎石术）或凝结后（用于体内碎石术）后，显着地改善了碎石术的成功率并降低了组织损伤的风险。本发明的一个方面涉及将反向热敏聚合物溶液注射到内腔中，从而防止结石或其碎片在体外或体内碎石术中迁移。

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