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    • 3. 发明授权
    • Method and device for the iontophoretic delivery of a drug
    • 药物离子电渗疗法的方法和装置
    • US08788031B2
    • 2014-07-22
    • US11586818
    • 2006-10-25
    • Gregory A. FischerMalcolm E. TaylorEdward M. Kolvek
    • Gregory A. FischerMalcolm E. TaylorEdward M. Kolvek
    • A61N1/30A61M31/00
    • A61N1/0448A61N1/0436A61N1/044
    • An iontophoretic drug delivery device storage apparatus and a method of using that device is disclosed. The device comprises a fluid reservoir, an electrode assembly and a tray apparatus. The fluid reservoir is capable of retaining a medicament and has a sealed fluid chamber defined by at least one seal. The seal includes a weaker region and a pinch-like configuration associated with that region such that application of pressure to the fluid reservoir breaks the weaker region of the seal, releasing the retained medicament. The electrode assembly comprises an active electrode, at least two passive electrodes a medicament carrying region, and a moat region around the medicament carrying region so that once fluid is delivered from the fluid reservoir to the electrode assembly the fluid is substantially retained in the medicament carrying means.
    • 公开了一种离子电渗药物输送装置的储存装置及其使用方法。 该装置包括流体储存器,电极组件和托盘装置。 流体储存器能够保持药物并且具有由至少一个密封件限定的密封流体室。 密封件包括与该区域相关联的较弱区域和夹紧形状,使得向流体储存器施加压力破坏密封件的较弱区域,释放保留的药剂。 电极组件包括有源电极,至少两个钝化电极,药物承载区域,以及围绕药物承载区域的护城河区域,使得一旦流体从流体储存器输送到电极组件,流体基本上保留在携带 手段。