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    • 6. 发明授权
    • Liquid surface control with an applied pressure signal in acoustic ink
printing
    • 液压表面控制与应用压力信号在声学印刷中的应用
    • US5229793A
    • 1993-07-20
    • US634248
    • 1990-12-26
    • Babur B. HadimiogluCalvin F. QuateButrus T. Khuri-Yakub
    • Babur B. HadimiogluCalvin F. QuateButrus T. Khuri-Yakub
    • B41J2/015B41J2/14
    • B41J2/14008B41J2002/14322
    • This invention is an acoustic ink printer. It has a pool of ink (33) with a free surface (36). Underneath the ink is a print head (10) which has droplet ejectors (14) for irradiating the free surface (36) of the pool of ink (33) with focused acoustic radiation (44). Over the free surface (36) of the pool of ink (33) is a membrane (16), with one or more apertures (20) aligned with the droplet ejectors (14), in intimate contact with the free surface (36) of the pool of ink (33). The apertures 20 are substantially larger than the waist diameter (46) of the focused acoustic radiation (44). An external pressure source (50) maintains the meniscus (48) of the pool of ink (33) substantially in the focal plane (52) of the focused acoustic radiation (44) during operation of the droplet ejectors (14). A piezoelectric crystal (24) is in intimate contact with the pool of ink (33). An electrical signal source (32) energizes the piezoelectric crystal (24) in order to apply a pressure signal (54) on demand to the pool of ink (33) during operation of the droplet ejectors (14). The different pressure signals (54) resulting from application of different electrical signals (29) to the piezoelectric crystal (24) can be utilized to eject individual droplets (38) of ink (33) from the free surface (34) of the ink (33) on demand, or to effect finer control over the free surface (34) of the ink (33) than is possible with the external pressure source (50) by itself.
    • 8. 发明授权
    • Near field acoustic ultrasonic microscope system and method
    • 近场声超声显微镜系统及方法
    • US5319977A
    • 1994-06-14
    • US718234
    • 1991-06-20
    • Calvin F. QuateButrus T. Khuri-YakubShinya AkamineBabur B. Hadimioglu
    • Calvin F. QuateButrus T. Khuri-YakubShinya AkamineBabur B. Hadimioglu
    • G01B17/00G01N29/06G01N29/24G01N37/00G01Q10/00G01Q20/00G01Q60/04G01Q60/06G01Q60/22G01S15/89G01N29/08
    • G01N29/0681G01H3/125G01Q60/32G01S15/8945G01N2291/02827G01N2291/048Y10S977/86
    • An acoustic microscope assembly for atomic level inspection of a target object includes a cantilever arm with a sharp tip on its lower surface and a zinc oxide piezoelectric thin film on its upper surface. High frequency excitation signals, having a frequency of at least 50 Megahertz, are applied to the piezoelectric thin film so as to generate high frequency acoustic signals that are transmitted through the sharp tip so as to impact on a target object. The assembly can either receive acoustic signals reflected by the target object, or it can receive acoustic signals that have propagated through the target object. One method of using this assembly is to apply a continuous wave signal to the piezoelectric thin film while scanning the target object, and measuring characteristics of the target object at various positions thereof by measuring the resonant frequency of the transmitted high frequency acoustic signals. Other methods include pulsed operation, and combining acoustic measurements with atomic force measurements and/or tunneling current measurements to characterize a target object. The acoustic microscope assembly can also be used for storing information on a substrate, by deforming the substrate at selected positions, and for reading such stored information by determining which positions on a substrate have been deformed.
    • 用于目标物体的原子级检查的声学显微镜组件包括在其下表面具有尖锐尖端的悬臂和在其上表面上的氧化锌压电薄膜。 将具有至少50兆赫兹频率的高频激励信号施加到压电薄膜上,以便产生通过尖尖传输以便对目标物体产生影响的高频声信号。 组件可以接收由目标对象反射的声信号,或者它可以接收已传播通过目标对象的声信号。 使用该组件的一种方法是在扫描目标物体的同时向压电薄膜施加连续波信号,并且通过测量发射的高频声信号的谐振频率来测量其各个位置处的目标物体的特性。 其他方法包括脉冲操作,以及将声学测量与原子力测量和/或隧道电流测量结合以表征目标对象。 声学显微镜组件还可以用于在基板上存储信息,通过使基板在选定位置变形,并且通过确定基板上的哪些位置已经变形来读取这些存储的信息。
    • 10. 发明申请
    • Detection of macromolecular complexes with harmonic cantilevers
    • 检测具有谐波悬臂的大分子复合物
    • US20100120023A1
    • 2010-05-13
    • US11404181
    • 2006-04-13
    • Ozgur SahinCalvin F. QuateOlav Solgaard
    • Ozgur SahinCalvin F. QuateOlav Solgaard
    • C12Q1/68G01N33/566G01N33/553G01N33/552G01N33/544
    • G01Q60/34
    • Method and apparatus which uses harmonic cantilevers, such as used in atomic force microscopy, to detect variations in the attractive and repulsive forces on a solid surface as a result of macromolecular binding, for example, hybridization of a single stranded DNA molecule attached to the surface with another DNA molecule. The complexed macromolecule is less flexible than an uncomplexed molecule. It will typically have more negative charge due to amino acids or DNA monomers. Both stiffness of the surface and the attractive capillary forces will change after binding and may be detected. By scanning the harmonic cantilever across a surface with macromolecules attached in tapping-mode and by recording the signals at the high frequency vibrations provided by harmonic cantilever, complexed molecules on a surface may be identified and quantified.
    • 使用诸如用于原子力显微镜的谐波悬臂的方法和装置来检测由于大分子结合而导致的固体表面上的吸引力和排斥力的变化,例如附着在表面上的单链DNA分子的杂交 与另一个DNA分子。 络合的大分子比未复合的分子灵活性低。 由于氨基酸或DNA单体,它通常会具有更多的负电荷。 表面的刚度和吸引的毛细管力将在结合后改变并且可以被检测。 通过用分接模式连接的大分子扫描谐波悬臂,并通过在由谐波悬臂提供的高频振动下记录信号,可以识别和量化表面上的复合分子。