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    • 6. 发明授权
    • Method and system for near-field spectroscopy using targeted deposition of nanoparticles
    • 使用纳米颗粒靶向沉积的近场光谱法的方法和系统
    • US08108943B2
    • 2012-01-31
    • US12324693
    • 2008-11-26
    • Mark S. Anderson
    • Mark S. Anderson
    • G01Q60/06
    • G01Q30/02G01J3/44G01N21/648G01N21/658G01Q60/06
    • There is provided in one embodiment of the invention a method for analyzing a sample material using surface enhanced spectroscopy. The method comprises the steps of imaging the sample material with an atomic force microscope (AFM) to select an area of interest for analysis, depositing nanoparticles onto the area of interest with an AFM tip, illuminating the deposited nanoparticles with a spectrometer excitation beam, and disengaging the AFM tip and acquiring a localized surface enhanced spectrum. The method may further comprise the step of using the AFM tip to modulate the spectrometer excitation beam above the deposited nanoparticles to obtain improved sensitivity data and higher spatial resolution data from the sample material. The invention further comprises in one embodiment a system for analyzing a sample material using surface enhanced spectroscopy.
    • 在本发明的一个实施例中提供了一种使用表面增强光谱分析样品材料的方法。 该方法包括以下步骤:用原子力显微镜(AFM)对样品材料进行成像,以选择用于分析的感兴趣区域,用AFM尖端将纳米颗粒沉积到感兴趣区域上,用光谱仪激发束照射沉积的纳米颗粒,以及 脱离AFM尖端并获取局部表面增强光谱。 该方法还可以包括使用AFM尖端来调制沉积的纳米粒子上方的光谱仪激发光束以获得改进的灵敏度数据和来自样品材料的较高空间分辨率数据的步骤。 本发明还在一个实施方案中包括使用表面增强光谱分析样品材料的系统。