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1. 发明授权

US5658516A Method of making a prospthetic implant 失效
标题翻译：制造假体植入物的方法
公开(公告)号：US5658516A
公开(公告)日：1997-08-19
申请号：US444033
申请日：1995-05-18
申请人： Barry Eppley , Thomas Sander , Robert D. Torgerson
发明人： Barry Eppley , Thomas Sander , Robert D. Torgerson
IPC分类号： A61F2/00 , A61F2/02 , A61F2/18 , A61F2/28 , A61F2/30 , A61L27/26 , B29C45/14 , B29C33/12
CPC分类号： A61F2/30721 , A61F2/2803 , A61F2/2875 , A61L27/26 , A61F2/18 , A61F2/186 , A61F2002/2807 , A61F2002/281 , A61F2002/2882 , A61F2002/2885 , A61F2002/2889 , A61F2002/30062 , A61F2002/30166 , A61F2002/30329 , A61F2002/30571 , A61F2002/30708 , A61F2002/30736 , A61F2002/30957 , A61F2002/30962 , A61F2210/0004 , A61F2220/0025 , A61F2230/0028 , A61F2250/0084 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179
摘要： Flexible prosthetic implants for repairing, replacing or augmenting hard tissue or bone. The flexible implant comprises a plurality of segments that are connected by flexible retainers which enable the segments to be re-oriented in relation to one another to accommodate the contour, size and shape of the body part being treated. A method for making such flexible prosthetic implants is also disclosed.
摘要翻译：用于修复，更换或增加硬组织或骨骼的柔性假体植入物。柔性植入物包括通过柔性保持器连接的多个段，其使得段能够相对于彼此重新定向以适应待处理的身体部位的轮廓，尺寸和形状。还公开了制造这种柔性假体植入物的方法。

2. 发明授权

US5496371A Prosthetic implant 失效
标题翻译：假体植入物
公开(公告)号：US5496371A
公开(公告)日：1996-03-05
申请号：US69452
申请日：1993-06-01
申请人： Barry Eppley , Thomas Sander , Robert D. Torgerson
发明人： Barry Eppley , Thomas Sander , Robert D. Torgerson
IPC分类号： A61F2/00 , A61F2/02 , A61F2/18 , A61F2/28 , A61F2/30 , A61L27/26
CPC分类号： A61F2/30721 , A61F2/2803 , A61F2/2875 , A61L27/26 , A61F2/18 , A61F2/186 , A61F2002/2807 , A61F2002/281 , A61F2002/2882 , A61F2002/2885 , A61F2002/2889 , A61F2002/30062 , A61F2002/30166 , A61F2002/30329 , A61F2002/30571 , A61F2002/30708 , A61F2002/30736 , A61F2002/30957 , A61F2002/30962 , A61F2210/0004 , A61F2220/0025 , A61F2230/0028 , A61F2250/0084 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179
摘要： Flexible prosthetic implants for repairing, replacing or augmenting hard tissue or bone. The flexible implant comprises a plurality of segments that are connected by flexible retainers which enable the segments to be re-oriented in relation to one another to accommodate the contour, size and shape of the body part being treated. A method for making such flexible prosthetic implants is also disclosed.
摘要翻译：用于修复，更换或增加硬组织或骨骼的柔性假体植入物。柔性植入物包括通过柔性保持器连接的多个段，其使得段能够相对于彼此重新定向以适应待处理的身体部位的轮廓，尺寸和形状。还公开了制造这种柔性假体植入物的方法。

3. 发明授权

US5037445A Method and kit for molding surgical implants 失效
标题翻译：用于模制外科植入物的方法和试剂盒
公开(公告)号：US5037445A
公开(公告)日：1991-08-06
申请号：US337908
申请日：1989-04-14
申请人： Thomas Sander , Robert D. Torgerson
发明人： Thomas Sander , Robert D. Torgerson
IPC分类号： A61F2/28 , A61F2/30 , A61F2/46 , A61L27/56
CPC分类号： A61F2/28 , A61L27/56 , A61F2/3094 , A61F2002/30583 , A61F2002/465 , A61F2002/4685 , A61F2210/0085 , Y10S623/911
摘要： A vacuum bag method for in-situ molding of surgical implants. The method comprises creating an implant precursor material composed of an aggregation of polymer beads coated with a hydrophilic monomer dispersion. A flexible bag containing the implant precursor is molded in-situ to a desired specific shape, and the implant precursor is then rigidified by applying a vacuum to the interior of the bag. The implant precursor is cured by heating to form a unitary porous prosthesis which may be implanted into body tissue to remedy bone defects.

4. 发明授权

US5876421A Residual xylene removal from sutures 失效
标题翻译：缝线残留二甲苯去除
公开(公告)号：US5876421A
公开(公告)日：1999-03-02
申请号：US823709
申请日：1997-03-25
申请人： Robert D. Torgerson , Ross R. Muth
发明人： Robert D. Torgerson , Ross R. Muth
IPC分类号： A61B17/06 , A61B17/04
CPC分类号： A61B17/06166 , A61L17/08 , A61L17/10 , A61L17/105 , A61B2017/00526
摘要： A method for removing residual xylene from sutures includes contacting the suture with water either subjecting the suture to an atmosphere containing water vapor or be immersing the suture in liquid water, followed by drying the suture.
摘要翻译：从缝合线去除残余二甲苯的方法包括使缝合线与水接触，使缝合线经受含水蒸汽的气氛或将缝合线浸入液体水中，然后干燥缝合线。

5. 发明授权

US06454787B1 Collagen hemostatic foam 有权
标题翻译：胶原止血泡沫
公开(公告)号：US06454787B1
公开(公告)日：2002-09-24
申请号：US09209600
申请日：1998-12-11
申请人： Francis B. Maddalo , Mark V. Iampietro , Stephen N. Eldridge , Robert D. Torgerson
发明人： Francis B. Maddalo , Mark V. Iampietro , Stephen N. Eldridge , Robert D. Torgerson
IPC分类号： A61B1708
CPC分类号： A61L15/325 , A61L15/425 , A61L2400/04 , C08L89/06 , Y10S128/08 , Y10S514/801
摘要： A hemostatic device formed of collagen particles and methods for producing and using the hemostatic device to control bleeding are provided. The collagen particles of the hemostatic device have a hemostatic activity that is equivalent to the hemostatic activity of the collagen particles from which the hemostatic device is formed. More preferably, the hemostatic devices are formed of Avitene® flour and the collagen particles of the hemostatic devices of the invention have a hemostatic activity equivalent to the hemostatic activity of Avitene® flour. The hemostatic devices optionally include hemostatic agents and/or therapeutic agents, to further promote hemostasis and wound healing.
摘要翻译：提供由胶原颗粒形成的止血装置以及用于制造和使用止血装置以控制出血的方法。止血装置的胶原颗粒具有等同于形成止血装置的胶原颗粒的止血活性的止血活性。更优选地，止血装置由面粉形成，并且本发明的止血装置的胶原颗粒具有与Avitene面粉的止血活性相当的止血活性。止血装置任选地包括止血剂和/或治疗剂，以进一步促进止血和伤口愈合。

6. 发明授权

US5366756A Method for treating bioabsorbable implant material 失效
标题翻译：用于治疗生物可吸收植入材料的方法
公开(公告)号：US5366756A
公开(公告)日：1994-11-22
申请号：US898340
申请日：1992-06-15
申请人： Michael P. Chesterfield , Robert D. Torgerson
发明人： Michael P. Chesterfield , Robert D. Torgerson
IPC分类号： A61L27/30 , A61L27/34 , A61L27/56 , A61F2/28
CPC分类号： A61L27/56 , A61L27/30 , A61L27/34 , Y10S525/937 , Y10S623/923
摘要： A porous bioabsorbable surgical implant material is prepared by coating particles of bioabsorbable polymer with a tissue ingrowth promoter. Typical polymers include polymers of glycolide, lactide, caprolactone, trimethylene carbonate, dioxanone and physical and chemical combinations thereof. The tissue ingrowth promoter can include calcium hydroxide and/or a hydrophillic coating material. The hydrophillic coating material can be bioabsorbable or non-bioabsorbable. A typical non-bioabsorbable hydrophillic coating material is polyhydroxymethylmethacrylate (PHEMA). The bioabsorbable implant material may also contain a therapeutic agent. Typical therapeutic agents include an antimicrobial agent, dye, growth factor and combinations thereof. Typically, the particles are prepared by rotary atomization and coated by spraying.
摘要翻译：通过用组织向内生长促进剂涂覆生物可吸收聚合物的颗粒来制备多孔生物可吸收的手术植入材料。典型的聚合物包括乙交酯，丙交酯，己内酯，三亚甲基碳酸酯，二氧杂环己酮及其物理和化学组合的聚合物。组织向内生长促进剂可以包括氢氧化钙和/或亲水性涂层材料。亲水性涂料可以是生物可吸收的或非生物可吸收的。典型的非生物可吸收的亲水性涂料是聚羟基甲基丙烯酸甲酯（PHEMA）。生物可吸收植入材料还可以含有治疗剂。典型的治疗剂包括抗微生物剂，染料，生长因子及其组合。通常，颗粒通过旋转雾化制备并通过喷雾涂覆。

7. 发明授权

US5697976A Bioabsorbable implant material 失效
标题翻译：生物可吸收植入材料
公开(公告)号：US5697976A
公开(公告)日：1997-12-16
申请号：US305535
申请日：1994-09-14
申请人： Michael P. Chesterfield , Robert D. Torgerson
发明人： Michael P. Chesterfield , Robert D. Torgerson
IPC分类号： A61L27/30 , A61L27/34 , A61L27/56 , A61F2/02
CPC分类号： A61L27/56 , A61L27/30 , A61L27/34 , Y10S525/937 , Y10S623/923
摘要： A porous bioabsorbable surgical implant material is prepared by coating particles of bioabsorbable polymer with tissue ingrowth promoter. Typical bioabsorbable polymers include polymers of glycolide, lactide, caprolactone, trimethylene carbonate, dioxanone, and physical and chemical combinations thereof. The tissue ingrowth promoter can include calcium hydroxide and/or a hydrophilic coating material. The hydrophilic coating material can be bioabsorbable or non-bioabsorbable. A typical non-bioabsorbable hydrophilic coating material is polyhydroxyethyl methacrylate (PHEMA). The bioabsorbable implant material may also contain a therapeutic agent. Typical therapeutic agents include an antimicrobial agent, dye, growth factors and combinations thereof.
摘要翻译：通过用组织向内生长促进剂涂覆生物可吸收聚合物的颗粒来制备多孔生物可吸收的手术植入材料。典型的生物可吸收聚合物包括乙交酯，丙交酯，己内酯，三亚甲基碳酸酯，二氧杂环己酮及其物理和化学组合的聚合物。组织向内生长促进剂可包括氢氧化钙和/或亲水涂层材料。亲水涂层材料可以是生物可吸收的或非生物可吸收的。典型的非生物可吸收亲水涂料是聚甲基丙烯酸羟乙酯（PHEMA）。生物可吸收植入材料还可以含有治疗剂。典型的治疗剂包括抗微生物剂，染料，生长因子及其组合。

8. 发明授权

US06361551B1 Collagen hemostatic fibers 有权
标题翻译：胶原止血纤维
公开(公告)号：US06361551B1
公开(公告)日：2002-03-26
申请号：US09209723
申请日：1998-12-11
申请人： Robert D. Torgerson , John Uhoch , Francis B. Maddalo , Stephen N. Eldridge
发明人： Robert D. Torgerson , John Uhoch , Francis B. Maddalo , Stephen N. Eldridge
IPC分类号： A61B1708
CPC分类号： A61L15/325 , A61L2400/04 , D01D5/06 , D01F4/00
摘要： A collagen fiber and methods for producing and using the collagen fiber of the inventions to prepare hemostatic fabrics to control bleeding are provided. The collagen particles (e.g., fibrils) of the fiber, preferably, have a hemostatic activity that is equivalent to the hemostatic activity of the collagen particles from which the fiber is formed. The collagen fibers of the invention and hemostatic fabrics formed thereof optionally include hemostatic agents and/or other therapeutic agents, to further promote hemostasis and wound healing.
摘要翻译：本发明提供了一种胶原纤维及其制备和使用本发明的胶原纤维以制备止血织物以控制出血的方法。纤维的胶原颗粒（例如纤维）优选具有与形成纤维的胶原颗粒的止血活性相当的止血活性。本发明的胶原纤维和由其形成的止血织物任选地包括止血剂和/或其它治疗剂，以进一步促进止血和伤口愈合。

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