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1. 发明授权

US08641778B2 Prosthesis attachment method and apparatus with soft tissue integrating seal 有权
标题翻译：假体附着方法和软组织集成密封装置
公开(公告)号：US08641778B2
公开(公告)日：2014-02-04
申请号：US12735452
申请日：2009-01-21
申请人： Alfred E. Mann , Byron L. Moran , Abram D. Janis , Paul Kaluzniak
发明人： Alfred E. Mann , Byron L. Moran , Abram D. Janis , Paul Kaluzniak
IPC分类号： A61F2/78
CPC分类号： A61B17/8625 , A61B17/60 , A61F2/2814 , A61F2/30749 , A61F2/78 , A61F2002/0086 , A61F2002/30013 , A61F2002/30029 , A61F2002/30434 , A61F2002/30448 , A61F2002/30451 , A61F2002/3093 , A61F2002/7887 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2250/0024 , A61F2310/00017 , A61F2310/00023 , A61F2310/00131 , A61F2310/00149
摘要： A method and apparatus for reducing the incident of infection proximate to an exit site where a prosthesis fastener, e.g., a bone screw, percutaneously penetrates a patient's skin/soft tissue. Infection reduction is achieved in accordance with the invention by growing a tissue integrating seal around the fastener proximate to the exit site.
摘要翻译：用于减少接近出口部位的感染事件的方法和装置，其中假体紧固件（例如骨螺钉）经皮穿透患者的皮肤/软组织。根据本发明通过在邻近出口部位附近围绕紧固件生长组织集成密封来实现感染减少。

2. 发明申请

US20120203199A1 Method and apparatus for providing access to an internal body organ 审中-公开
标题翻译：提供进入内部器官的方法和装置
公开(公告)号：US20120203199A1
公开(公告)日：2012-08-09
申请号：US13373787
申请日：2011-11-30
申请人： Alfred E. Mann , Gregory M. Harbers , Kelly A. Chapman , Abram D. Janis
发明人： Alfred E. Mann , Gregory M. Harbers , Kelly A. Chapman , Abram D. Janis
IPC分类号： A61M5/00 , A61M29/00 , A61B17/34 , A61M25/01
CPC分类号： A61M25/04 , A61M25/0017 , A61M25/0068 , A61M25/0606 , A61M25/0643 , A61M29/00 , A61M39/0208 , A61M39/0247 , A61M2039/0223 , A61M2039/0261
摘要： Catheter systems and methods for facilitating the delivery of a therapeutic agent directly to the interior of a body organ, and/or the extraction of material from said organ. The catheter distal end is placed within the body organ to be treated. The catheter may carry a fixation device near the catheter distal end. When implanted, the fixation device retains the catheter distal end in the organ despite normal patient activity. The fixation device may include porous material to promote soft tissue ingrowth for anchoring the catheter distal end within the organ.
摘要翻译：用于促进将治疗剂直接递送到身体器官内部的导管系统和方法，和/或从所述器官提取材料。将导管远端放置在待治疗的身体器官内。导管可以在导管远端附近携带固定装置。当植入时，尽管正常的患者活动，但是固定装置将导管远端保持在器官中。固定装置可以包括多孔材料以促进软组织向内生长以将导管远端锚定在器官内。

3. 发明申请

US20110029002A1 PROSTHESIS ATTACHMENT METHOD AND APPARATUS WITH SOFT TISSUE INTEGRATING SEAL 有权
标题翻译：软组织贴附方法和装置
公开(公告)号：US20110029002A1
公开(公告)日：2011-02-03
申请号：US12735452
申请日：2009-01-21
申请人： Alfred E. Mann , Byron L. Moran
发明人： Alfred E. Mann , Byron L. Moran
IPC分类号： A61B17/00
CPC分类号： A61B17/8625 , A61B17/60 , A61F2/2814 , A61F2/30749 , A61F2/78 , A61F2002/0086 , A61F2002/30013 , A61F2002/30029 , A61F2002/30434 , A61F2002/30448 , A61F2002/30451 , A61F2002/3093 , A61F2002/7887 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2250/0024 , A61F2310/00017 , A61F2310/00023 , A61F2310/00131 , A61F2310/00149
摘要： A method and apparatus for reducing the incident of infection proximate to an exit site where a prosthesis fastener, e.g., a bone screw, percutaneously penetrates a patient's skin/soft tissue. Infection reduction is achieved in accordance with the invention by growing a tissue integrating seal around the fastener proximate to the exit site.
摘要翻译：用于减少接近出口部位的感染事件的方法和装置，其中假体紧固件（例如骨螺钉）经皮穿透患者的皮肤/软组织。根据本发明通过在邻近出口部位附近围绕紧固件生长组织集成密封来实现感染减少。

4. 发明授权

US07127078B2 Implanted outer ear canal hearing aid 失效
标题翻译：植入式外耳道助听器
公开(公告)号：US07127078B2
公开(公告)日：2006-10-24
申请号：US10702565
申请日：2003-11-05
申请人： Alfred E. Mann , Albert S. Maltan , Yitzhak Zilberman , Byron L. Moran , Ronald J. Lebel
发明人： Alfred E. Mann , Albert S. Maltan , Yitzhak Zilberman , Byron L. Moran , Ronald J. Lebel
IPC分类号： H04R25/00
CPC分类号： H04R25/558 , H04R25/554 , H04R2225/31 , H04R2225/67
摘要： A hearing aid system including an implant (60) configured for insertion into a recess (40) formed under the skin of the retro-auricular space (50), which implant does not occlude the ear canal (30). The implant includes electronic circuitry (72), a transducer (65, e.g., speaker), antenna (64), and power source (66). The hearing aid also includes an external module (70), which module includes a microphone (163), electronics (172), antenna (164), and power source (166). A telemetry link (76) between the external module antenna and the implant antenna allows transmissions between the microphone module and the implant.
摘要翻译：一种助听器系统，包括构造成用于插入形成在后耳孔空间（50）的皮肤下方的凹部（40）中的植入物（60），该植入物不会封闭耳道（30）。植入物包括电子电路（72），换能器（65，例如扬声器），天线（64）和电源（66）。助听器还包括外部模块（70），该模块包括麦克风（163），电子设备（172），天线（164）和电源（166）。外部模块天线和植入物天线之间的遥测链路（76）允许麦克风模块和植入物之间的传输。

5. 发明授权

US08142344B2 Fully implantable hearing aid system 失效
标题翻译：完全植入式助听器系统
公开(公告)号：US08142344B2
公开(公告)日：2012-03-27
申请号：US11883728
申请日：2006-02-23
申请人： William H. Slattery, III , Alfred E. Mann , Byron L. Moran
发明人： William H. Slattery, III , Alfred E. Mann , Byron L. Moran
IPC分类号： H04R25/00
CPC分类号： H04R25/604 , H04R25/554 , H04R25/558 , H04R2225/67
摘要： A fully implantable hearing aid system comprised of an implantable sound generator module and an implantable sound receiver module connected by an implantable electric cable. The system includes: a) a sound generator module configured for implantation in subcutaneous tissue to place an output electric/acoustic (E/A) transducer, e.g., a speaker, immediately adjacent to, or preferably, extending percutaneously into, a patient's outer ear canal; b) a sound receiver module configured for implantation proximate to a patient's pinna to place an input acoustic/electric (AJE) transducer, e.g., a microphone, so that it is acoustically isolated from the E/A transducer; and c) an electric cable configured for implantation in subcutaneous tissue for directly electrically connecting said sound receiver module and said sound generator module.
摘要翻译：一种完全可植入的助听器系统，包括由可植入电缆连接的可植入声音发生器模块和可植入声音接收器模块。该系统包括：a）声音发生器模块，其配置用于植入皮下组织以将输出的电/声（E / A）换能器，例如扬声器紧邻或优选地经皮延伸到患者的外耳运河; b）声音接收器模块，其配置用于在患者的耳廓附近植入以放置例如麦克风的输入声/电（AJE）换能器，使得其与E / A换能器声学隔离; 以及c）配置用于植入皮下组织以直接电连接所述声音接收器模块和所述声音发生器模块的电缆。

6. 发明申请

US20080139874A1 Fully Implantable Hearing Aid System 失效
标题翻译：全植入式助听器系统
公开(公告)号：US20080139874A1
公开(公告)日：2008-06-12
申请号：US11883728
申请日：2006-02-23
申请人： William Slattery , Alfred E. Mann , Byron L. Moran
发明人： William Slattery , Alfred E. Mann , Byron L. Moran
IPC分类号： H04R25/00
CPC分类号： H04R25/604 , H04R25/554 , H04R25/558 , H04R2225/67
摘要： A fully implantable hearing aid system comprised of an implantable sound generator module and an implantable sound receiver module connected by an implantable electric cable. The system includes: a) a sound generator module configured for implantation in subcutaneous tissue to place an output electric/acoustic (E/A) transducer, e.g., a speaker, immediately adjacent to, or preferably, extending percutaneously into, a patient's outer ear canal; b) a sound receiver module configured for implantation proximate to a patient's pinna to place an input acoustic/electric (AJE) transducer, e.g., a microphone, so that it is acoustically isolated from the E/A transducer; and c) an electric cable configured for implantation in subcutaneous tissue for directly electrically connecting said sound receiver module and said sound generator module.
摘要翻译：一种完全可植入的助听器系统，包括由可植入电缆连接的可植入声音发生器模块和可植入声音接收器模块。该系统包括：a）声音发生器模块，其配置用于植入皮下组织以将输出的电/声（E / A）换能器，例如扬声器紧邻或优选地经皮延伸到患者的外耳运河; b）声音接收器模块，其配置用于在患者的耳廓附近植入以放置例如麦克风的输入声/电（AJE）换能器，使得其与E / A换能器声学隔离; 以及c）配置用于植入皮下组织以直接电连接所述声音接收器模块和所述声音发生器模块的电缆。

7. 发明授权

US08655455B2 Neural stimulator with percutaneous connectivity 有权
标题翻译：具有经皮连接的神经刺激器
公开(公告)号：US08655455B2
公开(公告)日：2014-02-18
申请号：US13500731
申请日：2010-09-30
申请人： Alfred E. Mann , Tom Xiaohai He
发明人： Alfred E. Mann , Tom Xiaohai He
IPC分类号： A61N1/00
CPC分类号： A61N1/0539 , A61M39/0247 , A61M2039/0261 , A61M2039/0267 , A61N1/0536 , A61N1/36017 , A61N1/36128
摘要： An implantable neurostimulation system includes both implantable and external components. Electrical connectivity between the external and implanted components is achieved through a plurality of feedthrough pins located within an insulative wall of a percutaneous port embedded in the skin. The percutaneous port has the general shape and appearance of a small thimble, embedded in the skin with its open end facing outwardly from the skin surface, and with its closed end located below the skin surface, thereby forming a cavity or dimple in the skin. Various plugs or cartridges can be removably inserted into the cavity of the percutaneous port, in various orientations, to facilitate appropriate connectivity between the external and implanted components of the system through selected ones of the feedthrough pins. A mesh edging secured around the periphery wall of the port promotes tissue ingrowth and vascularization, thereby forming a percutaneous seal around the port that prevents infection.
摘要翻译：植入式神经刺激系统包括可植入和外部组件。外部和植入部件之间的电连接通过位于皮肤内的经皮端口的绝缘壁内的多个穿通针来实现。经皮端口具有嵌入皮肤中的小套管的一般形状和外观，其开口端从皮肤表面向外，并且其封闭端位于皮肤表面下方，从而在皮肤中形成空腔或凹坑。可以以各种取向将各种插头或药筒可移除地插入到经皮端口的空腔中，以通过选定的馈通针来促进系统的外部部件和植入部件之间的适当连接。围绕端口的周围壁固定的网状边缘促进组织向内生长和血管形成，从而在端口周围形成防止感染的经皮密封。

8. 发明授权

US08202260B2 Partially implantable medical devices with cartridge movement sensor and associated methods 有权
标题翻译：部分可植入医疗设备，带有盒式移动传感器和相关方法
公开(公告)号：US08202260B2
公开(公告)日：2012-06-19
申请号：US12390430
申请日：2009-02-21
申请人： Alfred E. Mann , Tom Xiaohai He
发明人： Alfred E. Mann , Tom Xiaohai He
IPC分类号： A61M31/00
CPC分类号： A61M5/14244 , A61M5/14276 , A61M5/16854 , A61M39/0247 , A61M39/04 , A61M2205/12 , A61M2205/50 , A61M2205/6054 , A61M2205/8206
摘要： An apparatus for use with a fluid cartridge is disclosed. The apparatus includes a percutaneous port including an interior configured to receive the fluid cartridge, an implantable operative portion operably connected to the percutaneous port, a cartridge sensor configured to sense movement of the fluid cartridge relative to the percutaneous port, and a controller.
摘要翻译：公开了一种与流体盒一起使用的装置。该装置包括经皮端口，其包括构造成接收流体盒的内部，可操作地连接到经皮端口的可植入操作部分，配置成感测流体盒相对于经皮端口的运动的盒传感器，以及控制器。

9. 发明授权

US08175714B2 Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress 有权
标题翻译：植入式视网膜电极阵列配置，用于最小的视网膜损伤和减少视网膜应力的方法
公开(公告)号：US08175714B2
公开(公告)日：2012-05-08
申请号：US13044825
申请日：2011-03-10
申请人： Robert J. Greenberg , Alfred E. Mann , James S. Little , Karl-Heinz Ihrig , Brian V. Mech , Neil H. Talbot , DaoMin Zhou
发明人： Robert J. Greenberg , Alfred E. Mann , James S. Little , Karl-Heinz Ihrig , Brian V. Mech , Neil H. Talbot , DaoMin Zhou
IPC分类号： A61N1/375
CPC分类号： A61N1/0543
摘要： This invention is a retinal electrode array assembly and methods of using the same that facilitate surgical implant procedures by providing the operating surgeon with visual references and grasping means and with innovations that reduce actual and potential damage to the retina and the surrounding tissue.
摘要翻译：本发明是一种视网膜电极阵列组件及其使用方法，其通过向操作外科医生提供视觉参考和抓握装置以及减少对视网膜和周围组织的实际和潜在损伤的创新来促进手术植入程序。

10. 发明申请

US20100217239A1 PARTIALLY IMPLANTABLE MEDICAL DEVICES AND METHODS 有权
标题翻译：部分植入式医疗器械及方法
公开(公告)号：US20100217239A1
公开(公告)日：2010-08-26
申请号：US12390425
申请日：2009-02-21
申请人： Alfred E. Mann , Tom Xiaohai He
发明人： Alfred E. Mann , Tom Xiaohai He
IPC分类号： A61M5/142
CPC分类号： A61M5/14244 , A61M5/14276 , A61M5/16854 , A61M39/0247 , A61M39/04 , A61M2205/12 , A61M2205/50 , A61M2205/6054 , A61M2205/8206
摘要： Partially implantable medical devices and methods associated with partially implantable medical devices.
摘要翻译：部分可植入的医疗设备和与部分可植入医疗设备相关的方法。

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