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1. 发明授权

US4384042A Method and test composition for determination of hydrogen peroxide 失效
标题翻译：用于测定过氧化氢的方法和试验组合物
公开(公告)号：US4384042A
公开(公告)日：1983-05-17
申请号：US288123
申请日：1981-07-29
申请人： Akira Miike , Yoshiaki Shimizu , Toshio Tatano , Katsuyuki Watanabe
发明人： Akira Miike , Yoshiaki Shimizu , Toshio Tatano , Katsuyuki Watanabe
IPC分类号： G01N33/50 , C12Q1/28 , G01N31/00 , G01N33/52 , C12Q1/26 , C12Q1/44 , C12Q1/48 , C12Q1/54 , C12Q1/60 , C12Q1/62
CPC分类号： C12Q1/28 , G01N33/52 , C12Q2326/00 , Y10S435/805 , Y10S435/81
摘要： Disclosed is a method for the colorimetric determination of hydrogen peroxide in a sample by reacting a particular chromogen with the hydrogen peroxide in the presence of peroxidase and measuring the absorbancy of the reaction solution in the visible ray region. Also disclosed is a test composition for carrying out the determination.
摘要翻译：公开了一种通过在过氧化物酶存在下使特定色原体与过氧化氢反应并测量可见光区域中的反应溶液的吸光度的方式来比较测定样品中的过氧化氢的方法。还公开了用于进行测定的测试组合物。

2. 发明授权

US4851353A Method and test composition for determination of lipid peroxide 失效
标题翻译：测定脂质过氧化物的方法和试验组合物
公开(公告)号：US4851353A
公开(公告)日：1989-07-25
申请号：US11401
申请日：1987-02-04
申请人： Akira Miike , Yoshiaki Shimizu , Toshio Tatano , Katsuyuki Watanabe
发明人： Akira Miike , Yoshiaki Shimizu , Toshio Tatano , Katsuyuki Watanabe
IPC分类号： G01N33/50 , C12Q1/00 , C12Q1/28 , G01N31/00 , G01N33/52 , G01N33/72
CPC分类号： C12Q1/28 , G01N33/52 , G01N33/72 , C12Q2326/00 , Y10S436/904 , Y10T436/19 , Y10T436/193333 , Y10T436/206664
摘要： A method for the determination of peroxide in a sample is disclosed which comprises reacting the peroxide with a chromogen represented by the general formula (I) or (II) ##STR1## wherein R.sub.1 and R.sub.3 represent amino, mono- or di- substituted amino, hydroxyl or hydroxyalkyl, R.sub.4 and R.sub.5 represent hydrogen, alkyl, alkylene, acyl, halogen, sulphone, nitro, carboxyl, hydroxyl or hydroxyalkyl, R.sub.2 represents hydrogen, ##STR2## wherein R.sub.6 represents hydrogen, alkyl, aralkyl, alkylene, aryl or mono- or di- substituted aryl, and --Z-- may change to --Z.dbd. by resonance and represents --S--, --O--, --N.dbd., ##STR3## wherein R.sub.7, R.sub.8, R.sub.9 and R.sub.10 have the same significance as R.sub.6 in the presence of heme compound, iodide or bromide and measuring the absorbancy of the reaction solution in the visible ray region. Also disclosed is a test composition for the determination of peroxide which comprises a chromogen as defined above and a compound selected from a heme compound, iodide and bromide.
摘要翻译：公开了一种用于测定样品中过氧化物的方法，其包括使过氧化物与由通式（I）或（II）通式（I）表示的发色原反应：通式（II）：其中R1和R3代表氨基，单取代或二取代的氨基，羟基或羟基烷基，R4和R5代表氢，烷基，亚烷基，酰基，卤素，砜，硝基，羧基，羟基或羟烷基，R2代表氢，其中R 6表示氢，烷基，芳烷基，亚烷基，芳基或单取代或二取代的芳基，-Z-可以通过共振转变为-Z =，表示-S-，-O-，-N =，其中R7，R8，R9和R10在血红素化合物，碘化物或溴化物的存在下与R6具有相同的意义，并测量可见光区域中的反应溶液的吸光度。还公开了用于测定过氧化物的测试组合物，其包含如上定义的色原和选自血红素化合物，碘化物和溴化物的化合物。

3. 发明授权

US4978615A Method for the determination of the compound having mercapto group 失效
标题翻译：测定具有巯基的化合物的方法
公开(公告)号：US4978615A
公开(公告)日：1990-12-18
申请号：US157141
申请日：1988-02-10
申请人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
发明人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
IPC分类号： G01N33/50 , C12Q1/26 , C12Q1/28 , G01N33/68
CPC分类号： C12Q1/26 , C12Q1/28 , C12Q2326/00 , Y10S435/81
摘要： The present invention provides a method for the determination of a compound having mercapto group which comprises reacting the compound with a chromogen represented by the following general formula (I): ##STR1## wherein Y is hydrogen or hydroxyl; R.sub.1, R.sub.2 and R.sub.3 may be the same or different, and are groups represented by the following general formula (II), (III) or (IV): ##STR2## wherein Z (which may be the same or different) is hydroxyl, amino, substituted amino, alkyl, substituted alkyl, alkenyl, aryl, substituted aryl, acyl, halogen, nitro, sulfo, carboxyl or alkoxy; n is 0, 1, 2, or 3; provided that at least one Z in R.sub.1, R.sub.2 and R.sub.3 is hydroxyl, amino, or substituted amino, in the presence of peroxidase or thiol oxide reductase, and determining the pigment thus formed.
摘要翻译：本发明提供了一种用于测定具有巯基的化合物的方法，该方法包括使化合物与由以下通式（I）表示的色原体反应：其中Y为氢或羟基; （II），（III）或（IV）表示的基团可以相同或不同，R1，R2和R3可以相同或不同，并且是由以下通式（II），（III）或（IV）表示的基团：）其中Z（其可以相同或不同）为羟基，氨基，取代的氨基，烷基，取代的烷基，烯基，芳基，取代的芳基，酰基，卤素，硝基，磺基，羧基或烷氧基; n为0,1,2或3; 条件是在过氧化物酶或硫醇氧化物还原酶的存在下，R1，R2和R3中的至少一个Z是羟基，氨基或取代的氨基，并且确定如此形成的颜料。

4. 发明授权

US4824779A Method for the determination of the reduced form of nicotinamide adenine dinucleotide 失效
标题翻译：测定烟酰胺腺嘌呤二核苷酸还原形式的方法
公开(公告)号：US4824779A
公开(公告)日：1989-04-25
申请号：US706404
申请日：1985-02-28
申请人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
发明人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
IPC分类号： G01N33/50 , C12Q1/00 , C12Q1/26 , C12Q1/28
CPC分类号： C12Q1/008 , C12Q1/28 , C12Q2326/00
摘要： The present invention provides a method for the determination of NAD(P)H which comprises reacting a chromogen represented by the following general formula (I): ##STR1## wherein Y is hydrogen or hydroxyl; R.sub.1, R.sub.2 and R.sub.3 may be the same or different, and are groups represented by the following general formula (II), (III) or (IV): ##STR2## wherein Z is hydrogen, hydroxyl, amino, substituted amino, alkyl, substituted alkyl, alkenyl, aryl, substituted aryl, acyl, halogen, nitro, sulfo, carboxyl or alkoxy; n is 1, 2, or 3; provided that at least one Z in R.sub.1, R.sub.2 and R.sub.3 is hydroxyl, amino, or substituted amino; and Z.sub.s in Z.sub.n may be the same or different, with NAD(P)H in the presence of (1) peroxidase or thiol oxide reductase and (2) diaphorase or an electron carrier, and determining the pigment thus formed.
摘要翻译：本发明提供了一种测定NAD（P）H的方法，该方法包括使由以下通式（I）表示的色原反应：其中Y为氢或羟基; （II），（III）或（IV）表示的基团可以相同或不同，R1，R2和R3可以相同或不同，并且是由以下通式（II），（III）或（IV）表示的基团：）其中Z是氢，羟基，氨基，取代的氨基，烷基，取代的烷基，烯基，芳基，取代的芳基，酰基，卤素，硝基，磺基，羧基或烷氧基; n为1,2或3; 条件是R 1，R 2和R 3中的至少一个Z是羟基，氨基或取代的氨基; 并且在（1）过氧化物酶或硫醇氧化物还原酶和（2）心肌黄酶或电子载体的存在下，Zn中的Zs可以相同或不同，具有NAD（P）H，并且确定如此形成的颜料。

5. 发明授权

US4916058A Method and test composition for determination of hydrogen peroxide 失效
标题翻译：用于测定过氧化氢的方法和试验组合物
公开(公告)号：US4916058A
公开(公告)日：1990-04-10
申请号：US65126
申请日：1987-06-23
申请人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
发明人： Norihito Aoyama , Akira Miike , Yoshiaki Shimizu , Toshio Tatano
IPC分类号： G01N33/50 , C12Q1/28 , G01N31/00 , G01N31/22
CPC分类号： G01N31/22 , C12Q1/28 , C12Q2326/00 , Y10S435/81
摘要： Disclosed is a method for the colorimetric determination of hydrogen peroxide in a sample by reacting a particular chromogen with the hydrogen perioxide in the presence of peroxidase and measuring the absorbancy of the reaction solution in the visible or near inflared ray region. Also disclosed is a test composition for carrying out the determination.
摘要翻译：公开了通过在过氧化物酶的存在下使特定的色原体与氢氧化铂反应并测量可见光或近似辐射的光线区域中的反应溶液的吸光度来比较测定样品中过氧化氢的方法。还公开了用于进行测定的测试组合物。

6. 发明授权

US4416982A Composition and method for decomposing hydrogen peroxide 失效
标题翻译：用于分解过氧化氢的组合物和方法
公开(公告)号：US4416982A
公开(公告)日：1983-11-22
申请号：US321603
申请日：1981-11-16
申请人： Mitsuru Tsuda , Akira Miike , Yoshiaki Shimizu , Yasuharu Yokote , Toshio Tatano
发明人： Mitsuru Tsuda , Akira Miike , Yoshiaki Shimizu , Yasuharu Yokote , Toshio Tatano
IPC分类号： C01B15/01 , C12P1/00 , C12P3/00 , C12Q1/28 , C12Q1/60 , C12Q1/00 , C12Q1/26 , C12Q1/40 , C12Q1/42 , C12Q1/44 , C12Q1/52 , C12Q1/54
CPC分类号： C12Q1/28 , C12Q2326/00 , C12Q2326/96
摘要： A method for decomposing hydrogen peroxide is disclosed. The hydrogen peroxide is reacted with a compound represented by the formula (I) ##STR1## wherein Z represents OH or NR.sub.4.R.sub.5 wherein R.sub.4 and R.sub.5 are the same or different and represent hydrogen, alkyl, substituted alkyl or acyl, and R.sub.1,R.sub.2 and R.sub.3 are the same or different and represent hydrogen, halogen, alkyl, alkoxy, amino, nitro, carboxyl or sulphonyl, in the presence of peroxidase.
摘要翻译：公开了一种分解过氧化氢的方法。过氧化氢与式（I）表示的化合物反应，其中Z表示OH或NR4R5，其中R4和R5相同或不同，代表氢，烷基，取代的烷基或酰基，以及在过氧化物酶存在下，R 1，R 2和R 3相同或不同，代表氢，卤素，烷基，烷氧基，氨基，硝基，羧基或磺酰基。

7. 发明授权

US5246836A Peroxidase catalyzed enzyme assay by sample PRG-treatment 失效
标题翻译：过氧化物酶催化测定通过样品处理
公开(公告)号：US5246836A
公开(公告)日：1993-09-21
申请号：US562592
申请日：1990-08-03
申请人： Norihito Aoyama , Mitsuru Tsuda , Yoshiaki Shimizu , Seiji Sekine , Toshio Tatano
发明人： Norihito Aoyama , Mitsuru Tsuda , Yoshiaki Shimizu , Seiji Sekine , Toshio Tatano
IPC分类号： C12Q1/26 , C12Q1/28
CPC分类号： C12Q1/28 , C12Q1/26 , Y10T436/104165
摘要： A method for determination of an analyte in a sample containing reducing substances is disclosed. After the decomposition of the reducing substances by reaction with hydrogen peroxide formed by enzymatic Redox reaction using a component in the sample which does not participate in another enzymatic Redox reaction using the analyte, the remaining hydrogen peroxide is decomposed, and then the analyte is subjected to enzymatic Redox reaction to form hydrogen peroxide which is then determined by a known method.

8. 发明授权

US4722894A Method for the determination of ceruloplasmin activity 失效
标题翻译：测定血浆铜蓝蛋白活性的方法
公开(公告)号：US4722894A
公开(公告)日：1988-02-02
申请号：US697749
申请日：1985-02-04
申请人： Shigeru Matsumori , Yoshiaki Shimizu , Toshio Tatano
发明人： Shigeru Matsumori , Yoshiaki Shimizu , Toshio Tatano
IPC分类号： G01N33/90 , C12Q1/26 , C12Q1/00 , C12Q1/28
CPC分类号： C12Q1/26 , Y10S435/81
摘要： The present invention provides a method for the determination of ceruloplasmin activity, wherein a member selected from the group consisting of (a) ferrocene or derivatives thereof (b) metallocene and (c) chelate metal containing iron or copper is reacted with a chromogen in the presence of ceruloplasmin to form colored material which is determined photometrically, as well as a reagent suitable therefor.
摘要翻译：本发明提供了一种测定血浆铜蓝蛋白活性的方法，其中选自（a）二茂铁或其衍生物（b）茂金属和（c）含铁或铜的螯合金属的成员与色原体在存在铜蓝蛋白以形成由光度测定的有色材料，以及适于其的试剂。

9. 发明授权

US08354696B2 Semiconductor device and layout design apparatus of semiconductor device 有权
标题翻译：半导体器件的半导体器件和布局设计装置
公开(公告)号：US08354696B2
公开(公告)日：2013-01-15
申请号：US12979142
申请日：2010-12-27
申请人： Yoshiaki Shimizu , Kazuhiko Matsuki
发明人： Yoshiaki Shimizu , Kazuhiko Matsuki
IPC分类号： H01L27/118
CPC分类号： H01L27/11807 , H01L27/0207
摘要： A semiconductor device may include a plurality of logic circuits connected to each other through input and output terminals thereof. The plurality of logic circuits comprising a first sub-plurality of logic circuits coupled to a first one of different power systems. The first sub-plurality of logic circuits is laid out and adjacent to each other in a first direction. The first sub-plurality of logic circuits includes a first logic circuit and a second logic circuit. The second logic circuit is adjacent to the first logic circuit. The first logic circuit includes a first element comprising a first diffusion layer. The second logic circuit includes a second element comprising the first diffusion layer.
摘要翻译：半导体器件可以包括通过其输入和输出端子彼此连接的多个逻辑电路。多个逻辑电路包括耦合到不同电源系统中的第一个的第一子组多个逻辑电路。逻辑电路的第一子组合在第一方向相互布置并相邻。第一子逻辑电路包括第一逻辑电路和第二逻辑电路。第二逻辑电路与第一逻辑电路相邻。第一逻辑电路包括包括第一扩散层的第一元件。第二逻辑电路包括包括第一扩散层的第二元件。

10. 发明申请

US20120038719A1 LIQUID CONTAINER AND LIQUID EJECTION SYSTEM 有权
标题翻译：液体容器和液体喷射系统
公开(公告)号：US20120038719A1
公开(公告)日：2012-02-16
申请号：US13212921
申请日：2011-08-18
申请人： Yoshiaki Shimizu , Taku Ishizawa , Yuki Takeda , Syuichi Koganehira
发明人： Yoshiaki Shimizu , Taku Ishizawa , Yuki Takeda , Syuichi Koganehira
IPC分类号： B41J2/175
CPC分类号： B41J2/17506 , B41J2/175 , B41J2/17513 , B41J2/1752 , B41J2/17523 , B41J2/17553 , B41J2/19
摘要： A liquid container for supplying a liquid to a liquid ejection apparatus comprises: a liquid chamber provided to store the liquid; an air chamber connected with the liquid chamber to introduce the outside air into the liquid chamber with consumption of the liquid in the liquid chamber; an open-air hole provided to introduce the outside air into the air chamber; and a liquid inlet provided to fill the liquid into the liquid chamber, wherein the liquid inlet is located at a lower position than the open-air hole, in a filling attitude of the liquid container in which the liquid is filled into the liquid chamber.
摘要翻译：用于向液体喷射装置供应液体的液体容器包括：设置用于储存液体的液体室; 与所述液体室连接的空气室，以在所述液体室中的液体消耗的情况下将所述外部空气引入所述液体室; 设置用于将外部空气引入空气室的露天孔; 以及设置成将液体填充到液体室中的液体入口，其中液体入口位于比露天孔低的位置处，液体容器的填充位置处于液体容器中，其中液体被填充到液体室中。

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