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1. 发明授权

US07508851B2 Clock transfer device 失效
标题翻译：时钟传输设备
公开(公告)号：US07508851B2
公开(公告)日：2009-03-24
申请号：US11748172
申请日：2007-05-14
申请人： Dai Yoshitomi , Yohei Kobayashi , Kenji Torizuka
发明人： Dai Yoshitomi , Yohei Kobayashi , Kenji Torizuka
IPC分类号： H01S3/10
CPC分类号： H01S3/10092 , H01S3/06791 , H01S3/1112 , H01S3/1121 , H01S3/1394
摘要： A clock transfer device is designed to perform long-distance transfer of a reference clock, which is generated based on a high-precision frequency standard, toward a remote place. The clock transfer device includes a first mode-locked laser for generating a first optical pulse train having a first repetition frequency and a first wavelength, and a second mode-locked laser for generating a second optical pulse train having a second repetition frequency and a second wavelength. The first optical pulse train is introduced into a resonator of the second mode-locked laser via a wavelength multiplexing coupler so that the second repetition frequency is passively synchronized with the first repetition frequency; then, the second optical pulse train is transmitted via a single mode fiber.
摘要翻译：时钟传送装置被设计成对远程地方执行基于高精度频率标准产生的参考时钟的长距离传送。时钟传送装置包括用于产生具有第一重复频率和第一波长的第一光脉冲串的第一锁模激光器和用于产生具有第二重复频率的第二光脉冲序列的第二锁模激光器，波长。第一光脉冲串经由波长多路复用耦合器被引入到第二锁模激光器的谐振器中，使得第二重复频率与第一重复频率被动地同步; 那么，第二光脉冲串通过单模光纤传输。

2. 发明授权

US5459049A Motilin-like polypeptide and use thereof 失效
标题翻译：胃动素样多肽及其用途
公开(公告)号：US5459049A
公开(公告)日：1995-10-17
申请号：US3688
申请日：1993-01-13
申请人： Masayasu Kurono , Takahiko Matani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
发明人： Masayasu Kurono , Takahiko Matani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
IPC分类号： A61K38/00 , C07K14/63 , C12N15/16 , C12N15/63 , C12N15/67
CPC分类号： C07K14/63 , A61K38/00 , C07K2319/02
摘要： A process for the preparation of a polypeptide of the formula ##STR1## wherein A' is Pro, Gly, Asp or Ser; B' is Gly, Asn or Ser; C is Gln, Glu or Asp; D is Asn, Glu or Asp; X' is a residue of amino acid other than Met; E is Gln, Lys or Arg, and Y' is a residue of homoserine or homoserine-lactone, as well as a recombinant DNA and expression plasmid for preparing the polypeptide.
摘要翻译：制备式Phe-Val-A'-Ile-Phe-Thr-Tyr-B'-Glu-Leu-C-TR-Arg-X'-Gln-Glu-Lys-Glu的多肽的方法 -Arg-D-Lys-Gly-EY'，其中A'为Pro，Gly，Asp或Ser; B'是Gly，Asn或Ser; C是Gln，Glu或Asp; D是Asn，Glu或Asp; X'是Met以外的氨基酸残基; E是Gln，Lys或Arg，Y'是高丝氨酸或高丝氨酸 - 内酯的残基，以及用于制备多肽的重组DNA和表达质粒。

3. 发明授权

US06628684B2 Timing synchronization device of a pulsed laser and an optical synthesizer 失效
公开(公告)号：US06628684B2
公开(公告)日：2003-09-30
申请号：US10102883
申请日：2002-03-22
申请人： Yohei Kobayashi , Kenji Torizuka , Wei Zhiyi
发明人： Yohei Kobayashi , Kenji Torizuka , Wei Zhiyi
IPC分类号： H01S300
CPC分类号： H01S3/0823 , H01S3/005 , H01S3/07 , H01S3/0809 , H01S3/105 , H01S3/1112 , H01S3/1118 , H01S3/1307 , H01S3/1623 , H01S3/1658 , H01S3/2383
摘要： A timing synchronization device of a pulsed laser is composed of a first laser gain medium having a first gain region, a second laser gain medium having a second gain region that is not included in the first gain region, and first and second resonators provided with the first and second laser gain media, respectively, and arranged so that two laser pulses occurring in the first and second resonators, respectively, overlap with each other in one of the first and second laser gain media. The second laser gain medium has an oscillation wavelength at which the first laser gain medium crystal cannot cause oscillation.

4. 发明申请

US20070263681A1 CLOCK TRANSFER DEVICE 失效
标题翻译：时钟传输设备
公开(公告)号：US20070263681A1
公开(公告)日：2007-11-15
申请号：US11748172
申请日：2007-05-14
申请人： Dai YOSHITOMI , Yohei KOBAYASHI , Kenji TORIZUKA
发明人： Dai YOSHITOMI , Yohei KOBAYASHI , Kenji TORIZUKA
IPC分类号： H01S3/098 , H01S3/10 , H01S3/13
CPC分类号： H01S3/10092 , H01S3/06791 , H01S3/1112 , H01S3/1121 , H01S3/1394
摘要： A clock transfer device is designed to perform long-distance transfer of a reference clock, which is generated based on a high-precision frequency standard, toward a remote place. The clock transfer device includes a first mode-locked laser for generating a first optical pulse train having a first repetition frequency and a first wavelength, and a second mode-locked laser for generating a second optical pulse train having a second repetition frequency and a second wavelength. The first optical pulse train is introduced into a resonator of the second mode-locked laser via a wavelength multiplexing coupler so that the second repetition frequency is passively synchronized with the first repetition frequency; then, the second optical pulse train is transmitted via a single mode fiber.
摘要翻译：时钟传送装置被设计成对远程地方执行基于高精度频率标准产生的参考时钟的长距离传送。时钟传送装置包括用于产生具有第一重复频率和第一波长的第一光脉冲串的第一锁模激光器和用于产生具有第二重复频率的第二光脉冲序列的第二锁模激光器，波长。第一光脉冲串经由波长多路复用耦合器被引入到第二锁模激光器的谐振器中，使得第二重复频率与第一重复频率被动地同步; 那么，第二光脉冲串通过单模光纤传输。

5. 发明授权

US5432261A Motlin-like polypeptide and use thereof 失效
标题翻译： Motlin样多肽及其用途
公开(公告)号：US5432261A
公开(公告)日：1995-07-11
申请号：US943992
申请日：1992-09-11
申请人： Masayasu Kurono , Takahiko Mitani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
发明人： Masayasu Kurono , Takahiko Mitani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
IPC分类号： A61K38/00 , C07K14/63 , C12N15/16 , C07K14/00
CPC分类号： C07K14/63 , A61K38/00 , C07K2319/02
摘要： A pharmaceutical composition for stimulating peristaltic contraction in the intestinal canal which contains a pharmaceutically acceptable carrier or excipient and an effective amount of a polypeptide, or a salt thereof, having a pharmacological activity similar to motilin. The polypeptide has the formula B.sub.1 -Z.sub.1 -A.sub.1 -Z.sub.2 -B.sub.2 -Thr-B.sub.3 -A.sub.2 -Glu-Z.sub.3 -C-Arg-X'-Gln-Glu-Lys-Glu-Arg-D-Lys-Gly-E-Y, with Z.sub.1,Z.sub.2 and Z.sub.3 each being an amino acid residue having a hydrophobic side-chain, A.sub.1 and A.sub.2 each being an amino acid residue such as Pro, Gly, Asn and Ser, B.sub.1, B.sub.2 and B.sub.3 are each an amino acid residue having a side-chain with an aromatic ring, C is Gln, Glu or Asp, D is Asn, Glu or Asp, X' is an amino acid residue other than Met, E is Gln, Lys or Arg, and Y is homoserine, homoserine-lactone or a peptide chain having amino acid residues not exceeding 10 and containing homoserine or homoserine-lactone at the C-terminal where the first amino acid of said peptide chain is other than Lys, Arg or Pro.
摘要翻译：一种用于刺激肠道蠕动收缩的药物组合物，其含有药学上可接受的载体或赋形剂和有效量的具有与胃动素相似的药理活性的多肽或其盐。该多肽具有式B1-Z1-A1-Z2-B2-Thr-B3-A2-Glu-Z3-C-Arg-X'-Gln-Glu-Lys-Glu-Arg-D-Lys-Gly-EY， Z 1，Z 2和Z 3各自为具有疏水侧链的氨基酸残基，A1和A2各自为氨基酸残基，例如Pro，Gly，Asn和Ser，B1，B2和B3各自为具有具有芳环的侧链，C是Gln，Glu或Asp，D是Asn，Glu或Asp，X'是Met以外的氨基酸残基，E是Gln，Lys或Arg，Y是高丝氨酸，高丝氨酸 β-内酯或氨基酸残基不超过10的肽链，并且在所述肽链的第一个氨基酸不是Lys，Arg或Pro的C末端含有高丝氨酸或高丝氨酸 - 内酯。

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