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1. 发明授权

US07754205B2 Composition for transmucosal administration containing conenzyme Q as the active ingredient 有权
标题翻译：用于经粘膜给药的组合物，其含有辅酶Q作为活性成分
公开(公告)号：US07754205B2
公开(公告)日：2010-07-13
申请号：US10476208
申请日：2002-05-08
申请人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
发明人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
IPC分类号： A61K38/43
CPC分类号： A61K31/122 , A23L33/10 , A23V2002/00 , A61K9/0031 , A61K9/0048 , A61K9/02 , A61K31/047 , A61K31/09 , Y10S514/882 , A61K2300/00 , A23V2250/314
摘要： The present invention relates to the supply of coenzyme Q which is highly useful in maintaining human health, and provides a method and preparations whereby coenzyme Q can be efficiently supplied to patients having difficulties in oral administration, aged having swallowing difficulties and patients with diseases caused by topical disorders. It is found that the coenzyme Q concentration in the blood or topical mucosae can be elevated by using a composition for transmucosal administration containing oxidized coenzyme Q and/or reduced coenzyme Q as the active ingredient, wherein the total content of the oxidized coenzyme Q and the reduced coenzyme Q amounts to 0.0001 to 99% by weight of the whole composition.
摘要翻译：本发明涉及能够维持人体健康的辅酶Q的供给，提供可以将辅酶Q有效地供给口服给药困难的患者，患有吞咽困难的老年患者以及由局部疾病。通过使用含有氧化型辅酶Q和/或还原型辅酶Q作为活性成分的经粘膜给药用组合物，可以提高血液或局部粘膜中的辅酶Q浓度，其中氧化型辅酶Q和还原型辅酶Q占整个组合物的0.0001-99重量％。

2. 发明申请

US20060165672A1 Fatigue reducing agent 有权
公开(公告)号：US20060165672A1
公开(公告)日：2006-07-27
申请号：US10541020
申请日：2004-01-19
申请人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
发明人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
IPC分类号： A61K38/43 , A01N31/14
CPC分类号： A61K31/09 , A61K31/122
摘要： To maintain physical fitness and health of middle-aged and older persons living in the threshold of the aging society, the present invention provides a fatigue reducing agent which is highly effective for preventing and reducing fatigue, wherein the agent is made of a composition of substances that are very safe so that long-term administration is possible. A composition containing reduced coenzyme Q was found to be effective for preventing and reducing fatigue, including muscle fatigue. Since the fatigue reducing effect of the composition of the present invention is seen not only in young rats but also more pronounced in aged rats, the present invention can provide the fatigue reducing agent which is very useful, especially, for middle-aged and older persons as well as for young people.

3. 发明授权

US07015252B2 Compositions for lessening oxidative stress 有权
标题翻译：用于减轻氧化应激的组合物
公开(公告)号：US07015252B2
公开(公告)日：2006-03-21
申请号：US10492164
申请日：2002-10-15
申请人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
发明人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
IPC分类号： A61K31/12
CPC分类号： A61K31/085 , A61K31/122
摘要： The present invention provides an antioxidative composition with high safety, which is capable of lessening oxidative stress due to active oxygen species, free radicals, or the like in vivo, thereby preventing the occurrence or worsening of a disease. It was confirmed that by using a composition containing oxidized coenzyme Q and/or reduced coenzyme Q, the amount of urinary 8-hydroxydeoxyquanosine can be decreased in normal or diabetic animals. Also, in histopathological research of the spleens of diabetic rats, it was confirmed that spleen tissue denaturation caused by oxidative stress can be prevented. It was thus found that oxidative stress in vivo can be lessened. According to the present invention, oxidative stress in vivo can be lessened by using a composition containing coenzyme Q as an active ingredient.
摘要翻译：本发明提供了具有高安全性的抗氧化组合物，其能够在体内减少由活性氧，自由基等引起的氧化应激，从而防止疾病的发生或恶化。确认通过使用含有氧化型辅酶Q和/或还原型辅酶Q的组合物，在正常或糖尿病动物中尿8-羟基脱氧奎诺糖的量可以降低。此外，在糖尿病大鼠脾脏的组织病理学研究中，证实可以预防由氧化应激引起的脾脏组织变性。因此发现体内的氧化应激可以减轻。根据本发明，通过使用含有辅酶Q作为有效成分的组合物，可以减轻体内的氧化应激。

4. 发明申请

US20050070610A1 Dermal compositions containing coenzyme q as the active ingredient 审中-公开
标题翻译：含有辅酶q作为活性成分的皮肤组合物
公开(公告)号：US20050070610A1
公开(公告)日：2005-03-31
申请号：US10275882
申请日：2001-05-09
申请人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
发明人： Kenji Fujii , Taizo Kawabe , Kazunori Hosoe , Takayoshi Hidaka
IPC分类号： A61K8/34 , A61K8/35 , A61K8/86 , A61K9/00 , A61K9/06 , A61K9/107 , A61K31/05 , A61K31/075 , A61K31/12 , A61K31/122 , A61K47/10 , A61L15/44 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P17/08 , A61P37/08 , A61Q19/00 , A61Q19/10
CPC分类号： A61Q19/00 , A61K8/347 , A61K8/355 , A61K8/86 , A61K9/0014 , A61K9/06 , A61K31/05 , A61K31/122 , A61K47/10 , A61K2800/70 , A61L15/44 , A61L2300/216 , A61Q19/10
摘要： The present invention provides a composition for dermal application which comprises, as an active ingredient, an oxidized coenzyme Q represented by the formula (1): in which n represents an integer of 1 to 12, and/or a reduced coenzyme Q represented by the formula (2): in which n represents an integer of 1 to 12, the total content of the oxidized coenzyme Q and reduced coenzyme Q being 0.01 to 99% by weight relative to the whole amount of the composition. The present invention also provides a therapeutic composition for skin diseases, a cosmetic composition, a skin health care composition and a bath salt composition, each comprising the above composition for dermal application. The present invention is further provides a method for the treatment of skin diseases which comprises applying, to a patient suffering from a skin disease, the above-mentioned therapeutic composition for skin diseases, or a method for the treatment of skin diseases which comprises applying, to a patient suffering from a skin disease, the above therapeutic agent for skin diseases other than the oxidized coenzyme Q represented by the formula (1) and other than the reduced coenzyme Q represented by the formula (2) in parallel with a therapeutic composition for skin diseases.
摘要翻译：本发明提供了一种用于真皮应用的组合物，其包含作为活性成分的由式（1）表示的氧化型辅酶Q：其中n表示1〜12的整数，和/或由下式表示的还原型辅酶Q 式（2）：其中n表示1〜12的整数，相对于组合物的总量，氧化型辅酶Q和还原型辅酶Q的总含量为0.01〜99重量％。本发明还提供了一种皮肤病的治疗组合物，化妆品组合物，皮肤保健组合物和浴盐组合物，每种组合物包含上述用于真皮应用的组合物。本发明还提供了一种治疗皮肤病的方法，其包括向患有皮肤病的患者应用上述皮肤病治疗组合物或皮肤病治疗方法，对于患有皮肤病的患者，除了由式（1）表示的氧化型辅酶Q以外，除了式（2）所示的还原型辅酶Q以外，还可以使用与上述治疗组合物平行的上述皮肤病治疗剂，皮肤病。

5. 发明授权

US5057538A Hydroxystyrene compounds which have useful pharmaceutical utility 失效
标题翻译：具有有用的药用实用性的羟基苯乙烯化合物
公开(公告)号：US5057538A
公开(公告)日：1991-10-15
申请号：US587147
申请日：1990-09-24
申请人： Tadayoshi Shiraishi , Keiji Kameyama , Takeshi Domoto , Naohiro Imai , Yoshio Shimada , Yutaka Ariki , Kazunoro Hosoe , Masaji Kawatsu , Ikuo Katsumi , Takayoshi Hidaka , Kiyoshi Watanabe
发明人： Tadayoshi Shiraishi , Keiji Kameyama , Takeshi Domoto , Naohiro Imai , Yoshio Shimada , Yutaka Ariki , Kazunoro Hosoe , Masaji Kawatsu , Ikuo Katsumi , Takayoshi Hidaka , Kiyoshi Watanabe
IPC分类号： B21B31/16 , A61K31/26 , A61K31/27 , A61K31/275 , A61K31/34 , A61K31/425 , B21B31/02 , B21B31/20 , B21B33/00 , B21B37/18 , B21B37/72 , C07C253/30 , C07C255/34 , C07C255/41 , C07C255/44 , C07C255/53 , C07D207/38 , C07D209/34 , C07D231/36 , C07D277/20 , C07D277/36 , C07D277/54 , C07D279/16 , C07D307/32 , C07D307/33 , C07D307/52 , C07D307/58 , C07D417/12 , C09K3/00 , C07C121/75
CPC分类号： C07D277/20 , B21B31/02 , B21B31/203 , C07C255/00 , C07C255/34 , C07D207/38 , C07D209/34 , C07D231/36 , C07D277/36 , C07D277/54 , C07D279/16 , C07D307/58 , C07D417/12
摘要： A hydroxystyrene derivative represented by the formula (I): ##STR1## Wherein when R.sup.1 and R.sup.2 : phenyl group, benzyl group or phenethyl group, or R.sup.1 : R.sup.5 O--(R.sup.5 : H, a C.sub.1 to C.sub.5 alkyl group or benzyl group) and R.sup.2 : benzyl group or PhSCH.sub.2, R.sup.3 and R.sup.4 are taken together to represent --CONH--CS--S--, ##STR2## (X.sub.1 : H, a halogen, methyl group, ethyl group, R.sup.7 O--(R.sup.7 : methyl or ethyl group), nitro group, aminosulfonyl group or amino group, m.sup.1 : 1 or 2), pyridyl group, furyl group or thienyl group, n.sup.1 : an integer of 0 to 3); when R.sup.1 and R.sup.2 : phenyl group, benzyl group or phenethyl group, or R.sup.1 : R.sup.5 O--(R.sup.5 : as defined above) and R.sup.2 : benzyl group, R.sup.3 : cyano group and R.sup.4 : a carbamoyl group, or R.sup.3 and R.sup.4 are taken together to represent --CO--Y--CH.sub.2 CH.sub.2 --(Y: O or --NH--) or ##STR3## and when R.sup.1 and R.sup.2 : a C.sub.1 to C.sub.3 alkyl group, R.sup.3 and R.sup.4 are taken together to represent ##STR4## (n.sup.1, R.sup.6 : as defined above), or a salt thereof. The hydroxystyrene derivative or a salt thereof is a compound which is useful as an active ingredient of an antiallergic agent, a 5-lipoxybenase inhibiting agent, an antibacterial agent, a tyrosine kinase inhibiting agent, an ultraviolet absorber or a reverse transcriptase inhibiting agent, and also is useful as an intermediate for preparing various organic compounds.

6. 发明授权

US4853403A 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same 失效
标题翻译： 3-苯基硫代甲基苯乙烯衍生物，其制备方法，以及含有它们的抗过敏剂和酪氨酸激酶抑制剂
公开(公告)号：US4853403A
公开(公告)日：1989-08-01
申请号：US890034
申请日：1986-07-28
申请人： Tadayoshi Shiraishi , Naohiro Imai , Takeshi Domoto , Keiji Kameyama , Ikuo Katsumi , Takayoshi Hidaka , Kazunori Hosoe , Kiyoshi Watanabe
发明人： Tadayoshi Shiraishi , Naohiro Imai , Takeshi Domoto , Keiji Kameyama , Ikuo Katsumi , Takayoshi Hidaka , Kazunori Hosoe , Kiyoshi Watanabe
IPC分类号： C12N9/99 , A61K31/10 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/215 , A61K31/235 , A61K31/275 , A61K31/34 , A61K31/341 , A61K31/40 , A61K31/4015 , A61K31/415 , A61P3/00 , A61P11/00 , A61P35/00 , A61P37/08 , A61P43/00 , C07C67/00 , C07C313/00 , C07C317/44 , C07C323/16 , C07C323/29 , C07C323/56 , C07C323/65 , C07D207/26 , C07D207/267 , C07D207/38 , C07D231/32 , C07D231/36 , C07D231/56 , C07D307/33 , C07D307/58
CPC分类号： C07D207/267 , C07C323/00 , C07D231/32 , C07D307/33
摘要： A 3-phenylthiomethylstyrene derivative having the general formula (1): ##STR1## or salt thereof with a base, when X is hydroxyl group, R.sup.1 is hydrogen atom or R.sup.2 is hydrogen atom, a process for preparing the 3-phenylthiomethylstyrene derivative (1), and an antiallergic agent and a tyrosinekinase inhibiting agent containing the 3-phenylthiomethylstyrene derivative (1) as an effective component. The compound (1) of the present invention is a useful intermediate for preparing various organic compounds, and has excellent antiallergic and tyrosinekinase inhibiting activities.
摘要翻译：具有通式（1）的3-苯基硫代甲基苯乙烯衍生物：其中X为羟基，R 1为氢原子或R 2为氢原子时，其碱为碱的3-苯基硫代甲基苯乙烯衍生物（1）和含有3-苯基硫代甲基苯乙烯衍生物（1）作为有效成分的抗过敏剂和酪氨酸激酶抑制剂。本发明的化合物（1）是制备各种有机化合物的有用的中间体，具有优异的抗过敏和酪氨酸激酶抑制活性。

7. 发明授权

US5786349A Method for treating chlamydia infectious diseases by rifamycin derivative 失效
标题翻译：利福霉素衍生物治疗衣原体传染病的方法
公开(公告)号：US5786349A
公开(公告)日：1998-07-28
申请号：US762501
申请日：1996-12-09
申请人： Katsuji Yamashita , Kazunori Hosoe , Takayoshi Hidaka , George Todaro , Ribhi M. Shawar
发明人： Katsuji Yamashita , Kazunori Hosoe , Takayoshi Hidaka , George Todaro , Ribhi M. Shawar
IPC分类号： C07D498/18 , A61K31/495 , A61K31/535 , A61K31/5383 , A61K31/54 , A61P31/04 , A61K31/33
CPC分类号： A61K31/541 , A61K31/5383
摘要： A method for treatment of diseases caused by Chlamydia infection is disclosed comprising administering a rifamycin of the formula (I): ##STR1## wherein R.sup.1 is hydrogen atom or acetyl, and X is oxygen, sulfur or a group NR, in which R is hydrogen, an alkyl group having 1 to 7 carbon atoms or a group of the formula (II): ##STR2## in which n is an integer of 1 to 3; or a physiologically acceptable salt thereof.
摘要翻译：公开了治疗由衣原体感染引起的疾病的方法，其包括施用式（I）的利福霉素：其中R1是氢原子或乙酰基，X是氧，硫或基团NR，其中 R是氢，具有1至7个碳原子的烷基或式（II）的基团：其中n是1至3的整数; 或其生理上可接受的盐。

8. 发明授权

US5547683A Method for producing microgranulated particle 失效
标题翻译：微粒微粒生产方法
公开(公告)号：US5547683A
公开(公告)日：1996-08-20
申请号：US244375
申请日：1994-06-08
申请人： Yoshiaki Yano , Tamiji Fujimoto , Takayoshi Hidaka
发明人： Yoshiaki Yano , Tamiji Fujimoto , Takayoshi Hidaka
IPC分类号： A61K9/16 , B01J2/10 , B01J2/12 , B01J2/16 , A61K9/50 , B05D7/02 , B32B5/16
CPC分类号： B01J2/16 , A61K9/1694 , B01J2/10 , B01J2/12 , Y10T428/2982
摘要： The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized, is granulated, with a solution containing a binder alone or a binder and a surfactant being sprayed onto the surface thereof. The present invention allows to produce pharmaceutical preparations for poorly soluble and poorly absorbable drugs and preparations requiring a high content of the active ingredient. Also, it can provide an easy-to-handle powdery microgranulated particle in the field of food and fertilizers.
摘要翻译： PCT No.PCT / JP93 / 01442 Sec。 371日期：1994年6月8日 102（e）日期1994年6月8日PCT提交1993年10月6日PCT公布。出版物WO94 / 08709 日期：1994年04月28日本发明涉及一种粒径不大于0.2mm的微粒化微粒的制造方法，其特征在于，搅拌着平均粒径为10μm以下的细粉末，或流化的颗粒，其中包含单独的粘合剂或粘合剂和表面活性剂的溶液喷涂到其表面上。本发明允许制备难溶性和难吸收性药物和需要高含量活性成分的制剂的药物制剂。此外，它可以在食品和肥料领域提供易于处理的粉状微粒化颗粒。

9. 发明授权

US5270339A Phenoxybenzene derivative 失效
标题翻译：苯氧基苯衍生物
公开(公告)号：US5270339A
公开(公告)日：1993-12-14
申请号：US938164
申请日：1992-12-03
申请人： Kozo Yamamoto , Yoshihide Fuse , Hideyuki Kishida , Naoko Yasuhara , Toshiaki Miwa , Ikuo Katsumi , Takayoshi Hidaka
发明人： Kozo Yamamoto , Yoshihide Fuse , Hideyuki Kishida , Naoko Yasuhara , Toshiaki Miwa , Ikuo Katsumi , Takayoshi Hidaka
IPC分类号： C07D207/08 , C07D207/20 , C07D207/24 , C07D207/26 , C07D207/36 , C07D405/12 , C07D207/06
CPC分类号： C07D207/26 , C07D207/08 , C07D207/20 , C07D207/24 , C07D207/36 , C07D405/12
摘要： There are described a phenoxybenzene derivative having the formula (I): ##STR1## wherein R.sup.1 is hydrogen atom; an alkyl group having 1 to 3 carbon atoms; --OR.sup.6 or a halogen atom,R.sup.2 is hydrogen atom, nitro group or amino group,R.sup.3 is hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 5 carbon atoms, allyl group, vinyl group or --(CH.sub.2)n.sup.1 R.sup.7R.sup.4 is hydrogen atom, an alkyl group having 1 to 3 carbon atoms or --(CH.sub.2)n.sup.3 R.sup.25R.sup.5 hydrogen atom; an alkyl group having 1 to 3 carbon atoms; or phenyl group,X is ##STR2## wherein Y is oxygen atom or sulfur atom; or --CHR.sup.27 -- and line means a single bond or a double bond provided that n is 2 in case that the line means a single bond and n is 1 in case that the line means a double bond, ora pharmacologically acceptable salt thereof,a cognition enhancer comprising the same as an effective ingredient andan antidepressant comprising the same as an effective ingredient.
摘要翻译： PCT No.PCT / JP92 / 00410 Sec。 371日期1992年12月3日 102（e）日期1992年12月3日PCT提交1992年4月2日PCT公布。 WO92 / 17447 PCT出版物描述了具有式（I）的苯氧基苯衍生物：其中R 1是氢原子;（I）其中R 1是氢原子; 具有1至3个碳原子的烷基; -OR 6或卤原子，R 2为氢原子，硝基或氨基，R 3为氢原子，碳原子数1〜8的烷基，碳原子数3〜5的环烷基，烯丙基，乙烯基或 - （CH2）n1R7 R4为氢原子，碳原子数1〜3的烷基或 - （CH2）n3R25 R5氢原子; 具有1至3个碳原子的烷基; 或苯基，X是其中Y是氧原子或硫原子; 或-CHR27-，并且线表示单键或双键，条件是在线表示单键的情况下n为2，并且在该线表示双键的情况下n为1，或其药理学上可接受的盐，包含与有效成分相同的认知增强剂和包含其作为有效成分的抗抑郁药。

10. 发明授权

US5202341A Hydroxystyrene compounds having tyrosine kinase inhibiting activity 失效
标题翻译：具有酪氨酸激酶抑制活性的羟基苯乙烯化合物
公开(公告)号：US5202341A
公开(公告)日：1993-04-13
申请号：US735581
申请日：1991-07-25
申请人： Tadayoshi Shiraishi , Keiji Kameyama , Takeshi Domoto , Naohiro Imai , Yoshio Shimada , Yutaka Ariki , Kazunori Hosoe , Masaji Kawatsu , Ikuo Katsumi , Takayoshi Hidaka , Kiyoshi Watanabe
发明人： Tadayoshi Shiraishi , Keiji Kameyama , Takeshi Domoto , Naohiro Imai , Yoshio Shimada , Yutaka Ariki , Kazunori Hosoe , Masaji Kawatsu , Ikuo Katsumi , Takayoshi Hidaka , Kiyoshi Watanabe
IPC分类号： A61K31/26 , C07C255/34 , C07D207/38 , C07D209/34 , C07D231/36 , C07D277/20 , C07D277/36 , C07D277/54 , C07D279/16 , C07D307/58 , C07D417/12
CPC分类号： C07D277/20 , C07C255/00 , C07C255/34 , C07D207/38 , C07D209/34 , C07D231/36 , C07D277/36 , C07D277/54 , C07D279/16 , C07D307/58 , C07D417/12
摘要： A hydroxystyrene derivative represented by the formula (I): ##STR1## wherein when R.sup.1 and R.sup.2 : phenyl group, benzyl group or phenethyl group, or R.sup.1 : R.sup.5 O- (R.sup.5 : H, a C.sub.1 to C.sub.5 alkyl group or benzyl group) and R.sup.2 : benzyl group or PhSCH.sub.2, R.sup.3 and R.sup.4 are taken together to represent --CONH--CS--S--, ##STR2## (X.sup.1 : H, a halogen, methyl group, ethyl group, R.sup.7 O-- (R.sup.7 : methyl or ethyl group), nitro group, aminosulfonyl group or amino group, m.sup.1 : 1 or 2), pyridyl group, furyl group or thienyl group, n.sup.1 : an integer of 0 to 3); when R.sup.1 and R.sup.2 : phenyl group, benzyl group or phenethyl group, or R.sup.1 : R.sup.5 O-- (R.sup.5 : as defined above) and R.sup.2 : benzyl group, R.sup.3 : cyano group and R.sup.4 : a carbamoyl group, or R.sup.3 and R.sup.4 are taken together to represent --CO--Y--CH.sub.2 CH.sub.2 -- (Y: O or --NH--) or ##STR3## and when R.sup.1 and R.sup.2 : a C.sub.1 to C.sub.3 alkyl group, R.sup.3 and R.sup.4 are taken together to represent ##STR4## (n.sup.1, R.sup.6 : as defined above), or a salt thereof. The hydroxystyrene derivative or a salt thereof is a compound which is useful as an active ingredient of an antiallergic agent, a 5-lipoxygenase inhibiting agent, an antibacterial agent, a tyrosine kinase inhibiting agent, an ultraviolet absorber or a reverse transcriptase inhibiting agent, and also is useful as an intermediate for preparing various organic compounds.
摘要翻译：由式（I）表示的羟基苯乙烯衍生物：其中当R1和R2：苯基，苄基或苯乙基或R1：R5O-（R5：H，C1-C5烷基或苄基基团）和R 2：苄基或PhSCH 2，R 3和R 4一起表示-CONH-CS-S-，或（X1：H，卤素，甲基，乙基，R7O-（ R7：甲基或乙基），硝基，氨基磺酰基或氨基，m1：1或2），吡啶基，呋喃基或噻吩基，n1：0〜3的整数）。当R1和R2：苯基，苄基或苯乙基或R1：R5O-（R5：如上定义）和R2：苄基，R3：氰基和R4：氨基甲酰基，或R3和R4合在一起表示-CO-Y-CH 2 CH 2 - （Y：O或-NH-）或，并且当R 1和R 2为C 1至C 3烷基时，R 3和R 4一起表示（n1，R6 ：如上所定义），或其盐。羟基苯乙烯衍生物或其盐是可用作抗变应性剂的活性成分，5-脂氧合酶抑制剂，抗菌剂，酪氨酸激酶抑制剂，紫外线吸收剂或逆转录酶抑制剂的化合物，以及也可用作制备各种有机化合物的中间体。

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