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    • 2. 发明授权
    • Article for detecting power drift in the putout of a diode array source
    • 用于检测二极管阵列源的电源漂移的文章
    • US06275516B1
    • 2001-08-14
    • US09109661
    • 1998-07-02
    • Susanne ArneySandra Greenberg KosinskiJane Deborah LeGrange
    • Susanne ArneySandra Greenberg KosinskiJane Deborah LeGrange
    • H01S3091
    • H01S5/4025H01S3/0941H01S5/0683
    • A method and article for monitoring and controlling power drift in the output of a diode array is described. The diode array is used, for example, as a light pump for a fiber laser. In one embodiment, an improved fiber laser includes the light pump, which launches light into a laser cavity. The fiber laser further includes a sampler operable to receive at least a portion of the light before it is launched into the laser cavity. The sampled portion represents a known fraction of the total light signal generated by the light pump. In some embodiments, the sampled light is directed, via the sampler, to a photodetector. The photodetector converts the sampled light into a first electrical signal and delivers it to a processor. The processor is operable to compare the electrical signal with a set-point signal representative of a desired power output of the sampled portion of the launched light. To the extent that a differential exists between the set point signal and the first electrical signal, the desired optical power is not being launched into the lasing cavity. If such a differential exists, the processor generates and sends a control signal to a controllable current source. The control signal is operable to increase or decrease the current delivered from the controllable current source to the light pump to correct power drifts in light pump output.
    • 描述了一种用于监控和控制二极管阵列输出功率漂移的方法和文章。 二极管阵列例如用作光纤激光器的光泵。 在一个实施例中,改进的光纤激光器包括将光发射到激光腔中的光泵。 光纤激光器还包括采样器,其可操作以在光被发射到激光腔内之前接收光的至少一部分。 采样部分表示由光泵产生的总光信号的已知分数。 在一些实施例中,采样光通过采样器被引导到光电检测器。 光电检测器将采样的光转换成第一电信号并将其传送到处理器。 处理器可操作以将电信号与表示所发射光的采样部分的期望功率输出的设定点信号进行比较。 在设定点信号和第一电信号之间存在差分的情况下,期望的光功率未被发射到激光腔中。 如果存在这样的差分,则处理器产生并发送控制信号到可控电流源。 控制信号可操作以增加或减少从可控电流源传递到光泵的电流,以校正光泵输出中的功率漂移。
    • 6. 发明申请
    • Drug delivery stent
    • 药物输送支架
    • US20050203613A1
    • 2005-09-15
    • US10798064
    • 2004-03-11
    • Susanne ArneyTimofei KroupenkineDonald Weiss
    • Susanne ArneyTimofei KroupenkineDonald Weiss
    • A61F2/00A61F2/92A61F2/06
    • A61L31/14A61F2/92A61F2210/0076A61F2250/0002A61F2250/001A61F2250/0035A61F2250/0039A61F2250/0056A61F2250/0067A61F2250/0068
    • An implantable stent comprises a tubular member having an interior surface and an exterior surface, with a region of at least one of the surfaces being hydrophobic. The region is provided with an array of microstructures or nanostructures that covers first portions of the surface but leaves second portions exposed in the interstices of the array. These structures cause the region to have a dynamically controllable hydrophobicity. In one embodiment, a control device, which is affixed to the tubular member, varies the hydrophobicity of the region. In another embodiment, which is particularly applicable to the delivery of a medicinal substance to fluids in body vessels, the stent also includes such a medicinal substance that adheres to the exposed portions until the control device alters the hydrophobicity of the region and causes the substance to be released into a body fluid in contact with the stent. Various ways to load the stent are described. In yet another embodiment, the tubular member is provided with a mechanism that enables the shape of the stent (e.g., its diameter) in vivo to be controlled dynamically, again by means of external wireless communication. In one more embodiment, sensors are affixed to the tubular member to enable fluid parameters (e.g., pressure, flow rate) to be monitored remotely.
    • 可植入支架包括具有内表面和外表面的管状构件,其中至少一个表面的区域是疏水性的。 该区域设置有覆盖表面的第一部分的微观结构或纳米结构阵列,但是留下暴露在阵列间隙中的第二部分。 这些结构使得该区域具有动态可控的疏水性。 在一个实施例中,固定到管状构件的控制装置改变该区域的疏水性。 在另一个特别适用于将药物输送到体内血液的实施方案中,支架还包括粘附到暴露部分的药物,直到控制装置改变该区域的疏水性并使物质 被释放到与支架接触的体液中。 描述加载支架的各种方式。 在另一个实施例中,管状构件设置有能够通过外部无线通信来动态地控制体内支架形状(例如其直径)的机构。 在另一个实施例中,传感器固定到管状构件以使流体参数(例如,压力,流速)能够被远程监控。
    • 9. 发明授权
    • Drug delivery stent
    • 药物输送支架
    • US08915957B2
    • 2014-12-23
    • US10798064
    • 2004-03-11
    • Susanne ArneyTimofei Nikita KroupenkineDonald Weiss
    • Susanne ArneyTimofei Nikita KroupenkineDonald Weiss
    • A61F2/82A61F2/92A61L31/14
    • A61L31/14A61F2/92A61F2210/0076A61F2250/0002A61F2250/001A61F2250/0035A61F2250/0039A61F2250/0056A61F2250/0067A61F2250/0068
    • An implantable stent comprises a tubular member having an interior surface and an exterior surface, with a region of at least one of the surfaces being hydrophobic. The region is provided with an array of microstructures or nanostructures that covers first portions of the surface but leaves second portions exposed in the interstices of the array. These structures cause the region to have a dynamically controllable hydrophobicity. In one embodiment, a control device, which is affixed to the tubular member, varies the hydrophobicity of the region. In another embodiment, which is particularly applicable to the delivery of a medicinal substance to fluids in body vessels, the stent also includes such a medicinal substance that adheres to the exposed portions until the control device alters the hydrophobicity of the region and causes the substance to be released into a body fluid in contact with the stent. Various ways to load the stent are described. In yet another embodiment, the tubular member is provided with a mechanism that enables the shape of the stent (e.g., its diameter) in vivo to be controlled dynamically, again by means of external wireless communication. In one more embodiment, sensors are affixed to the tubular member to enable fluid parameters (e.g., pressure, flow rate) to be monitored remotely.
    • 可植入支架包括具有内表面和外表面的管状构件,其中至少一个表面的区域是疏水性的。 该区域设置有覆盖表面的第一部分的微观结构或纳米结构阵列,但是留下暴露在阵列间隙中的第二部分。 这些结构使得该区域具有动态可控的疏水性。 在一个实施例中,固定到管状构件的控制装置改变该区域的疏水性。 在另一个特别适用于将药物输送到体内血液的实施方案中,支架还包括粘附到暴露部分的药物,直到控制装置改变该区域的疏水性并使物质 被释放到与支架接触的体液中。 描述加载支架的各种方式。 在另一个实施例中,管状构件设置有能够通过外部无线通信来动态地控制体内支架形状(例如其直径)的机构。 在另一个实施例中,传感器固定到管状构件以使流体参数(例如,压力,流速)能够被远程监控。