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1. 发明申请

US20230035343A1 METHOD FOR PREDICTING ONSET OF CHORIOAMNIONITIS 有权
公开(公告)号：US20230035343A1
公开(公告)日：2023-02-02
申请号：US17782059
申请日：2020-12-04
申请人： Shingo MIYAMOTO , Daichi URUSHIYAMA , Kenichiro HATA
发明人： Shingo MIYAMOTO , Daichi URUSHIYAMA , Fusanori YOTSUMOTO , Kenichiro HATA
IPC分类号： C12Q1/689 , C12Q1/6869
摘要： Provided is a method for predicting the onset of chorioamnionitis, which may predict the onset of chorioamnionitis with high sensitivity. The method including obtaining a base sequence data group of a 16S ribosomal RNA gene in a sample from the vagina of a subject; detecting the presence of a bacterium selected from a bacterial group represented by G1 below based on the data group obtained; and associating the sample with the likelihood of onset of chorioamnionitis based on the number of bacterial species detected. The bacterial group G1: Finegoldia magna; Streptococcus anginosus; Aerococcus christensenii; Lactobacillus jensenii; Ureaplasma parvum; Prevotella disiens; Lactobacillus vaginalis; Prevotella buccalis; Dialister micraerophilus; Atopobium vaginae; Prevotella bivia; Prevotella amnii; Anaerococcus lactolytcus; Streptococcus agalactiae; Anaerococcus tetradius; Bacteroides fragilis; Gardnerella vaginalis; Mycoplasma hominis; and Sneathia sanguinegens.

2. 发明申请

US20220288132A1 METHOD FOR PREPARATION OF BLASTOCYST 有权
公开(公告)号：US20220288132A1
公开(公告)日：2022-09-15
申请号：US17690559
申请日：2022-03-09
申请人： Shingo Miyamoto
发明人： Shingo MIYAMOTO , Katsuro TACHIBANA , Toyofumi HIRAKAWA , Fumitoshi KOGA
IPC分类号： A61K35/54 , C12N5/073
摘要： Provided a method for preparing a blastocyst. The method includes culturing a fertilized egg in a culture medium containing bubbles containing a reducing gas. The reducing gas may contain at least one selected from the group consisting of hydrogen, carbon monoxide, nitrogen monoxide, and hydrogen sulfide. The bubbles may have an average particle size of from 10 nm to 1,000 nm.

3. 发明申请

US20150179329A1 REACTOR AND REACTOR MANUFACTURING METHOD, AND POWER CONVERTER 有权
标题翻译：反应器和反应器制造方法和功率转换器
公开(公告)号：US20150179329A1
公开(公告)日：2015-06-25
申请号：US14420192
申请日：2013-11-05
申请人： Shingo Miyamoto
发明人： Shingo Miyamoto
IPC分类号： H01F27/08 , H02M1/12 , H02M1/42 , H01F41/12
CPC分类号： H01F27/085 , H01F27/022 , H01F41/127 , H01F2027/406 , H02M1/12 , H02M1/42 , Y10T29/4902
摘要： A manufacturing method for a reactor in which resin for covering at least a part of a coil is formed integrally with the coil comprise a step of manufacturing a molded product and a step of attaching a temperature sensor such that the temperature sensor is opposed to a first face. The step of manufacturing the molded product includes following i) to iii): i) arranging the reactor in a cavity space for injection-molding of resin; ii) fixing the coil with the surface of a mold brought into contact with the first face and a second face located at positions which sandwich the coil on the periphery of the coil; and iii) injecting resin into the cavity space to cover at least a coil surface around the first face and a coil surface around the second face with the resin, with the first face and the second face exposed.
摘要翻译：一种反应器的制造方法，其中用于覆盖线圈的至少一部分的树脂与线圈一体地形成，包括制造模制产品的步骤和附接温度传感器的步骤，使得温度传感器与第一面对。制造模制产品的步骤包括以下i）至iii）：i）将反应器设置在用于树脂注射成型的空腔中; ii）将线圈固定在与第一面接触的模具的表面上;以及第二面，其位于将线圈夹在线圈周边的位置; 以及iii）将树脂注入所述空腔中以至少覆盖所述第一面周围的线圈表面和围绕所述树脂的所述第二面周围的线圈表面，其中所述第一面和所述第二面露出。

4. 发明申请

US20110052595A1 MONOCLONAL ANTIBODY CAPABLE OF BINDING TO HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR 失效
标题翻译：结合抗HEPARIN结合的单克隆抗体抗生长因子生长因子
公开(公告)号：US20110052595A1
公开(公告)日：2011-03-03
申请号：US12494472
申请日：2009-06-30
申请人： Eisuke MEKADA , Ryo Iwamoto , Shingo Miyamoto , Kenya Shitara , Akiko Furuya , Kazuyasu Nakamura , Kumiko Takahashi , Hiroshi Ando , Kazuhiro Masuda , Yuka Sasaki
发明人： Eisuke MEKADA , Ryo Iwamoto , Shingo Miyamoto , Kenya Shitara , Akiko Furuya , Kazuyasu Nakamura , Kumiko Takahashi , Hiroshi Ando , Kazuhiro Masuda , Yuka Sasaki
IPC分类号： A61K39/395 , C07K16/22 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/04 , A61P35/00
CPC分类号： A61K39/39558 , A61K2039/505 , C07K16/22 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76
摘要： Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.
摘要翻译：需要用于治疗与HB-EGF升高有关的疾病的药物。本发明提供了结合细胞膜结合的HB-EGF，膜型HB-EGF和分泌型HB-EGF的单克隆抗体或其抗体片段。

5. 发明申请

US20110034673A1 MONOCLONAL ANTIBODY CAPABLE OF BINDING TO HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR 失效
公开(公告)号：US20110034673A1
公开(公告)日：2011-02-10
申请号：US12609434
申请日：2009-10-30
申请人： Eisuke MEKADA , Ryo IWAMOTO , Shingo MIYAMOTO , Kenya SHITARA , Akiko FURUYA , Kazuyasu NAKAMURA , Kumiko TAKAHASHI , Hiroshi ANDO , Kazuhiro MASUDA , Yuka SASAKI
发明人： Eisuke MEKADA , Ryo IWAMOTO , Shingo MIYAMOTO , Kenya SHITARA , Akiko FURUYA , Kazuyasu NAKAMURA , Kumiko TAKAHASHI , Hiroshi ANDO , Kazuhiro MASUDA , Yuka SASAKI
IPC分类号： C07K16/00 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/04
CPC分类号： C07K16/22 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76
摘要： Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.

6. 发明申请

US20090105135A1 Therapeutic Agent for Cancer 有权
标题翻译：癌症治疗剂
公开(公告)号：US20090105135A1
公开(公告)日：2009-04-23
申请号：US11917706
申请日：2006-06-20
申请人： Eisuke Mekada , Shingo Miyamoto
发明人： Eisuke Mekada , Shingo Miyamoto
IPC分类号： A61K38/16 , A61P35/00
CPC分类号： A61K38/164
摘要： The present invention provides a cancer therapeutic agent containing as an active ingredient a substance, particularly CRM197 which inhibits the binding of HB-EGF to EGF receptor by binding to HB-EGF, wherein a cancer is selected from the group consisting of a bladder cancer, a colon cancer or peritoneal metastatic cancers of a stomach cancer and a pancreatic cancer.
摘要翻译：本发明提供一种癌症治疗剂，其含有作为活性成分的物质，特别是CRM197，其通过结合HB-EGF抑制HB-EGF与EGF受体的结合，其中癌症选自膀胱癌，胃癌和胰腺癌的结肠癌或腹膜转移性癌症。

7. 发明申请

US20060270600A1 Anti-cancer agents 审中-公开
标题翻译：抗癌剂
公开(公告)号：US20060270600A1
公开(公告)日：2006-11-30
申请号：US11438767
申请日：2006-05-23
申请人： Eisuke Mekada , Shingo Miyamoto
发明人： Eisuke Mekada , Shingo Miyamoto
IPC分类号： A61K39/05 , C07K14/34
CPC分类号： C07K16/1285 , A61K38/164 , A61K2039/505
摘要： An anti-cancer agent comprising as an active component a protein which is a diphtheria toxin mutant such as CRM197, has an activity to inhibit binding of HB-EGF to an EGR receptor and substantially does not have toxicity of diphtheria toxin. The anti-cancer agent is particularly effective for the treatment of ovarian cancer, breast cancer and prostate cancer.
摘要翻译：包含作为白喉毒素突变体如CRM197的蛋白质作为活性成分的抗癌剂具有抑制HB-EGF与EGR受体结合并且基本上不具有白喉毒素毒性的活性。抗癌剂对卵巢癌，乳腺癌和前列腺癌的治疗特别有效。

8. 发明授权

US09449751B2 Reactor and reactor manufacturing method, and power converter 有权
标题翻译：电抗器和电抗器的制造方法以及电源转换器
公开(公告)号：US09449751B2
公开(公告)日：2016-09-20
申请号：US14420192
申请日：2013-11-05
申请人： Shingo Miyamoto
发明人： Shingo Miyamoto
IPC分类号： H01F27/08 , H01F27/02 , H01F41/12 , H02M1/12 , H02M1/42 , H01F27/40
CPC分类号： H01F27/085 , H01F27/022 , H01F41/127 , H01F2027/406 , H02M1/12 , H02M1/42 , Y10T29/4902
摘要： A manufacturing method for a reactor in which resin for covering at least a part of a coil is formed integrally with the coil comprise a step of manufacturing a molded product and a step of attaching a temperature sensor such that the temperature sensor is opposed to a first face. The step of manufacturing the molded product includes following i) to iii): i) arranging the reactor in a cavity space for injection-molding of resin; ii) fixing the coil with the surface of a mold brought into contact with the first face and a second face located at positions which sandwich the coil on the periphery of the coil; and iii) injecting resin into the cavity space to cover at least a coil surface around the first face and a coil surface around the second face with the resin, with the first face and the second face exposed.
摘要翻译：一种反应器的制造方法，其中用于覆盖线圈的至少一部分的树脂与线圈一体地形成，包括制造模制产品的步骤和附接温度传感器的步骤，使得温度传感器与第一面对。制造模制产品的步骤包括以下i）至iii）：i）将反应器设置在用于树脂注射成型的空腔中; ii）将线圈固定在与第一面接触的模具的表面上;以及第二面，其位于将线圈夹在线圈周边的位置; 以及iii）将树脂注入所述空腔中以至少覆盖所述第一面周围的线圈表面和围绕所述树脂的所述第二面周围的线圈表面，其中所述第一面和所述第二面露出。

9. 发明授权

US08718444B2 Video search device, video search method, recording medium, program, and integrated circuit 有权
标题翻译：视频搜索装置，视频搜索方法，记录介质，程序和集成电路
公开(公告)号：US08718444B2
公开(公告)日：2014-05-06
申请号：US13389144
申请日：2011-03-17
申请人： Kouji Miura , Masaya Yamamoto , Shingo Miyamoto
发明人： Kouji Miura , Masaya Yamamoto , Shingo Miyamoto
IPC分类号： H04N5/92
CPC分类号： G11B27/105 , G06F17/3079 , G06K9/4652 , G06K9/50 , H04N5/44543 , H04N5/85 , H04N9/8227 , H04N9/8233 , H04N21/44008 , H04N21/45455 , H04N21/4828 , H04N21/84
摘要： A video search device extracts a plurality of objects each contained in a different one of frames of a video, assigns a weight value to each of the extracted objects based on a time-series feature of the frame containing the object, and searches for an object similar to each of the extracted objects based on the extracted objects each having the weight value assigned thereto.
摘要翻译：视频搜索装置提取包含在视频的不同帧中的多个对象，基于包含对象的帧的时间序列特征向每个提取的对象分配权重值，并搜索对象基于提取的每个具有分配给其的权重值的对象，与每个提取的对象类似。

10. 发明申请

US20120197923A1 INFORMATION PROCESSING DEVICE, PROCESSING METHOD, COMPUTER PROGRAM, AND INTEGRATED CIRCUIT 有权
标题翻译：信息处理设备，处理方法，计算机程序和集成电路
公开(公告)号：US20120197923A1
公开(公告)日：2012-08-02
申请号：US13499740
申请日：2011-07-06
申请人： Shingo Miyamoto , Kouji Miura , Shunji Harada
发明人： Shingo Miyamoto , Kouji Miura , Shunji Harada
IPC分类号： G06F17/30
CPC分类号： G06F17/30265
摘要： An information processing device that attaches common accompanying data to a content group composed of contents. The information processing device acquires the contents, acquires one or more characteristics of each acquired content and searches among reference data items in order to acquire one or more reference data items that each include any of the one or more characteristics, each reference data item having attached thereto at least one attribute used for identifying the reference data item, the reference data items being data other than the contents. The information processing device then specifies, among the attributes attached to the acquired one or more reference data items, an attribute that also pertains to the contents, uses the specified attribute as an attribute for identifying each of the contents, and attaches the specified attribute to each of the contents.
摘要翻译：一种信息处理设备，其将公共附带数据附加到由内容组成的内容组。信息处理装置获取内容，获取每个获取的内容的一个或多个特征，并在参考数据项之间进行搜索，以获取每个包括一个或多个特征中的任一个的一个或多个参考数据项，每个参考数据项已附加至少一个用于识别参考数据项的属性，参考数据项是除内容之外的数据。然后，信息处理装置在附加到所获取的一个或多个参考数据项的属性中指定也属于内容的属性，使用指定的属性作为用于标识每个内容的属性，并将指定的属性附加到每个内容。

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