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1. 发明申请

US20070041496A1 SYSTEM AND METHOD OF REMOTELY ANALYZING OPERATION OF A RADIATION THERAPY SYSTEM 审中-公开
标题翻译：辐射治疗系统的远程分析操作系统及方法
公开(公告)号：US20070041496A1
公开(公告)日：2007-02-22
申请号：US11459104
申请日：2006-07-21
申请人： Gustavo Olivera , John Hughes , Robert Cravens , Thomas Mackie , Paul Reckwerdt , David Murray , Kenneth Ruchala , Jeffrey Kapatoes , Eric Schloesser , Eric Schnarr
发明人： Gustavo Olivera , John Hughes , Robert Cravens , Thomas Mackie , Paul Reckwerdt , David Murray , Kenneth Ruchala , Jeffrey Kapatoes , Eric Schloesser , Eric Schnarr
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/103 , A61N2005/1074
摘要： Systems and methods for utilizing remote access to a radiation therapy system. Remote access to the radiation therapy system can assist in providing quality assurance processes, service and maintenance procedures, patient monitoring, and statistical analysis.
摘要翻译：利用远程访问放射治疗系统的系统和方法。远程访问放射治疗系统可以帮助提供质量保证过程，服务和维护程序，患者监测和统计分析。

2. 发明申请

US20070076846A1 SYSTEM AND METHOD OF DELIVERING RADIATION THERAPY TO A MOVING REGION OF INTEREST 有权
标题翻译：向移动兴趣区域提供辐射治疗的系统和方法
公开(公告)号：US20070076846A1
公开(公告)日：2007-04-05
申请号：US11459074
申请日：2006-07-21
申请人： Kenneth Ruchala , Gustavo Olivera , Weiguo Lu , Eric Schnarr , John Hughes , Jeffrey Kapatoes , Thomas Mackie , Paul Reckwerdt
发明人： Kenneth Ruchala , Gustavo Olivera , Weiguo Lu , Eric Schnarr , John Hughes , Jeffrey Kapatoes , Thomas Mackie , Paul Reckwerdt
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/103 , A61N5/1042 , A61N5/1067 , A61N2005/1061 , G06F19/00 , G06F19/321 , G06F19/3481 , G16H50/50
摘要： A system for and method of delivering radiation therapy to a moving region of interest is disclosed. The method, in one implementation, includes the acts of generating a plurality of treatment plans for providing radiation therapy, delivering radiation therapy to the patient following one of the plurality of treatment plans, monitoring the patient while providing radiation therapy, and changing the treatment plan based at least in part on monitoring the patient.
摘要翻译：公开了将辐射治疗递送到感兴趣的移动区域的系统和方法。该方法在一个实施中包括产生用于提供放射治疗的多个治疗计划的动作，在多个治疗计划中的一个治疗计划之后向患者传送放射疗法，在提供放射治疗的同时监测患者，以及改变治疗计划至少部分地基于监测患者。

3. 发明申请

US20060285639A1 System and method of treating a patient with radiation therapy 有权
标题翻译：用放射线治疗患者的系统和方法
公开(公告)号：US20060285639A1
公开(公告)日：2006-12-21
申请号：US11431319
申请日：2006-05-10
申请人： Gustavo Olivera , Thomas Mackie , Jeffrey Kapatoes , John Hughes , Kenneth Ruchala , Paul Reckwerdt
发明人： Gustavo Olivera , Thomas Mackie , Jeffrey Kapatoes , John Hughes , Kenneth Ruchala , Paul Reckwerdt
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61B6/027 , A61N5/1049
摘要： A radiation therapy treatment system and method of treating a patient with radiation. The system integrates positioning of the patient, treatment planning, and delivery of the plan. As a result of the integration of imaging capabilities into the treatment apparatus, and efficient processes for contouring and planning, a patient can be treated in approximately 20 minutes or less. The method includes acquiring image data from the patient, defining a target region with one or more predefined shapes, generating a treatment plan based on the defined target region, and delivering radiation to the target region.
摘要翻译：放射疗法治疗系统和治疗患者放射线的方法。该系统整合了患者的定位，治疗计划和计划的交付。作为将成像能力整合到治疗装置中的结果以及用于轮廓和规划的有效过程，可以在大约20分钟或更短时间内对患者进行治疗。该方法包括从患者获取图像数据，用一个或多个预定形状定义目标区域，基于所定义的目标区域生成治疗计划，以及将辐射传送到目标区域。

4. 发明申请

US20080083871A1 Method and apparatus for calibrating a radiation therapy treatment system 有权
标题翻译：用于校准放射治疗治疗系统的方法和装置
公开(公告)号：US20080083871A1
公开(公告)日：2008-04-10
申请号：US11881542
申请日：2007-07-27
申请人： Robert Cravens , Kenneth Ruchala , Gustavo Olivera , Daniel Lucas , Andrea Cox , Paul Reckwerdt , Cleber Souza , Douglas Henderson
发明人： Robert Cravens , Kenneth Ruchala , Gustavo Olivera , Daniel Lucas , Andrea Cox , Paul Reckwerdt , Cleber Souza , Douglas Henderson
IPC分类号： G12B13/00 , A61N5/10
CPC分类号： A61N5/1048 , A61N5/1042 , A61N5/1075 , A61N2005/1076
摘要： A radiation treatment system and method of commissioning the system, the system including a gantry, a radiation source operable to produce a beam of radiation, and a measurement device. The measurement device is physically connected to the gantry, and includes a multi-dimensional scanning arm, and a detector. The method includes generating radiation from the radiation source, passing the radiation through an attenuation block, and receiving radiation with the measurement device. The measurement device is positioned such that it is not in contact with water. Data is generated from the radiation received and the system is commissioned using the generated data to match system characteristics to a previously defined standard.
摘要翻译：辐射处理系统和调试系统的方法，所述系统包括台架，可操作以产生辐射束的辐射源以及测量装置。测量装置物理地连接到台架，并且包括多维扫描臂和检测器。该方法包括从辐射源产生辐射，使辐射通过衰减块，以及利用测量装置接收辐射。测量装置定位成使其不与水接触。数据是从所接收的辐射产生的，并且系统使用生成的数据进行调试，以将系统特性与先前定义的标准相匹配。

5. 发明申请

US20070041499A1 METHOD AND SYSTEM FOR EVALUATING QUALITY ASSURANCE CRITERIA IN DELIVERY OF A TREATMENT PLAN 有权
标题翻译：评估治疗计划中提供质量保证标准的方法和系统
公开(公告)号：US20070041499A1
公开(公告)日：2007-02-22
申请号：US11459152
申请日：2006-07-21
申请人： Weiguo Lu , Gustavo Olivera , Jeffrey Kapatoes , Kenneth Ruchala , Eric Schnarr , John Hughes , Thomas Mackie , Paul Reckwerdt
发明人： Weiguo Lu , Gustavo Olivera , Jeffrey Kapatoes , Kenneth Ruchala , Eric Schnarr , John Hughes , Thomas Mackie , Paul Reckwerdt
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1075
摘要： System and method of evaluating quality assurance criteria related to the delivery of a radiation therapy treatment plan. The method includes the acts of acquiring image data of a patient, generating a treatment plan for the patient based at least in part on the image data, the treatment plan including a calculated radiation dose to be delivered to the patient, acquiring an on-line image of the patient in substantially a treatment position, delivering at least a portion of the calculated radiation dose to the patient, monitoring quality assurance criteria related to the delivery of the treatment plan, calculating the radiation dose received by the patient, and determining whether delivery of the treatment plan occurred as intended based on the quality assurance criteria and the radiation dose received by the patient.
摘要翻译：评估与放射治疗计划相关的质量保证标准的系统和方法。该方法包括获取患者的图像数据的动作，至少部分地基于图像数据生成针对患者的治疗计划，治疗计划包括计算出的要递送给患者的辐射剂量，获取在线将患者的图像基本上处于治疗位置，将计算的辐射剂量的至少一部分递送给患者，监测与治疗计划的递送相关的质量保证标准，计算患者接收的辐射剂量，以及确定是否递送的治疗计划根据质量保证标准和患者接受的放射剂量进行预期的发生。

6. 发明申请

US20050201516A1 Method for modification of radiotherapy treatment delivery 有权
标题翻译：放射治疗传递的修改方法
公开(公告)号：US20050201516A1
公开(公告)日：2005-09-15
申请号：US10506866
申请日：2003-03-06
申请人： Kenneth Ruchala , Gustavo Olivera , Jeffrey Kapatoes , Paul Reckwerdt , Weiguo Lu , John Hughes
发明人： Kenneth Ruchala , Gustavo Olivera , Jeffrey Kapatoes , Paul Reckwerdt , Weiguo Lu , John Hughes
IPC分类号： A61N20060101 , A61N1/00 , A61N5/10 , G06T1/00
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N2005/1061 , G06F19/00
摘要： The present invention provides a novel method of contoured-anatomy dose repositioning (CADR) as a means to automatically reposition a patient to better recover the planned dose distribution without reoptimize the treatment plan. Specifically, CADR utilizes planning CT images, the planned dose distribution, and on-line images for repositioning dose distribution on a given day. Contours are also placed upon the images using manual, automatic, template-based, or other techniques. CADR then optimizes the rigid-body repositioning of the patient so that the daily dose distribution closely matches the planned dose distribution. The present invention also provides a method of multiple-margin optimization with daily selection (MMODS) to improve radiation delivery without reoptimization. During the initial optimization procedure, plans are optimized for several margins of various contours (e.g., tight, medium, loose, etc.), or with different objectives (e.g., aggressive treatment, sensitive structure sparing, etc.). Similarly, if multiple patient image sets are available, plans can be optimized for the different anatomical layouts, either using current information, or accumulated information regarding the superposition of organ locations in the combination of images. A user can then choose in real time from a variety of optimized plans, generally with different margins, during the treatment process, and thereby compensate for a recognized change in size or position of the tumor or neighboring tissue.
摘要翻译：本发明提供了一种轮廓解剖学剂量重新定位（CADR）的新方法，作为自动重新定位患者的手段，以更好地恢复计划的剂量分布，而不重新优化治疗计划。具体来说，CADR利用计划的CT图像，计划的剂量分布和在线图像在给定的一天重新定位剂量分布。使用手动，自动，基于模板或其他技术的轮廓也被放置在图像上。然后，CADR优化患者的刚体重新定位，使得日剂量分布与计划的剂量分布密切相关。本发明还提供了一种利用日常选择（MMODS）进行多边距优化的方法，以改善辐射递送而不重新优化。在初始优化过程中，针对各种轮廓（例如紧密，中等，松散等）或不同目标（例如，积极的治疗，敏感的结构节省等）的几个边缘优化了计划。类似地，如果多个患者图像组可用，则针对不同的解剖结构布局可以优化计划，使用当前信息或关于图像组合中器官位置的叠加的累积信息。然后，用户可以在处理过程中从各种优化的计划（通常具有不同的边缘）实时地选择，从而补偿肿瘤或相邻组织的大小或位置的公认变化。

7. 发明申请

US20070104316A1 SYSTEM AND METHOD OF RECOMMENDING A LOCATION FOR RADIATION THERAPY TREATMENT 审中-公开
标题翻译：用于放射治疗治疗的位置的系统和方法
公开(公告)号：US20070104316A1
公开(公告)日：2007-05-10
申请号：US11459126
申请日：2006-07-21
申请人： Kenneth Ruchala , Thomas Mackie , Gustavo Olivera , Paul Reckwerdt , John Hughes , Robert Cravens , Eric Schnarr , Jeffrey Kapatoes
发明人： Kenneth Ruchala , Thomas Mackie , Gustavo Olivera , Paul Reckwerdt , John Hughes , Robert Cravens , Eric Schnarr , Jeffrey Kapatoes
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/103 , A61N2005/1074
摘要： Systems and methods for utilizing remote access to a radiation therapy treatment system. Remote access to the radiation therapy treatment system can assist in providing quality assurance processes, service and maintenance procedures, patient monitoring, and statistical analysis.
摘要翻译：利用远程访问放射治疗系统的系统和方法。远程访问放射治疗系统可以帮助提供质量保证过程，服务和维护程序，患者监测和统计分析。

8. 发明申请

US20070195930A1 SYSTEM AND METHOD OF GENERATING CONTOUR STRUCTURES USING A DOSE VOLUME HISTOGRAM 有权
标题翻译：使用剂量组织生成轮廓结构的系统和方法
公开(公告)号：US20070195930A1
公开(公告)日：2007-08-23
申请号：US11459143
申请日：2006-07-21
申请人： Jeffrey Kapatoes , Gustavo Olivera , Eric Schnarr , Weiguo Lu , Kenneth Ruchala , Paul Reckwerdt , John Hughes , Thomas Mackie
发明人： Jeffrey Kapatoes , Gustavo Olivera , Eric Schnarr , Weiguo Lu , Kenneth Ruchala , Paul Reckwerdt , John Hughes , Thomas Mackie
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1069 , A61N2005/1074
摘要： A system and method of defining a new region of interest for an existing region of interest using a dose volume histogram. The method includes the acts of generating a dose volume histogram of radiation dose for a pre-existing region of interest, selecting a subset of the dose volume histogram, and defining a new region of interest that corresponds to the selected subset of the dose volume histogram.
摘要翻译：使用剂量体积直方图来定义现有感兴趣区域的新感兴趣区域的系统和方法。该方法包括产生用于预先存在的感兴趣区域的辐射剂量的剂量体积直方图的动作，选择剂量体积直方图的子集，以及定义对应于剂量体积直方图的选定子集的新的感兴趣区域。

9. 发明申请

US20070043286A1 METHOD AND SYSTEM FOR ADAPTING A RADIATION THERAPY TREATMENT PLAN BASED ON A BIOLOGICAL MODEL 有权
标题翻译：基于生物模型适应放射治疗方案的方法和系统
公开(公告)号：US20070043286A1
公开(公告)日：2007-02-22
申请号：US11459105
申请日：2006-07-21
申请人： Weiguo Lu , Kenneth Ruchala , Gustavo Olivera , Eric Schnarr , Jeffrey Kapatoes , Thomas Mackie , Paul Reckwerdt
发明人： Weiguo Lu , Kenneth Ruchala , Gustavo Olivera , Eric Schnarr , Jeffrey Kapatoes , Thomas Mackie , Paul Reckwerdt
IPC分类号： A61B5/05
CPC分类号： A61N5/103 , A61N5/1031 , A61N5/1037 , A61N5/1038 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1069 , A61N2005/1072 , G06F19/00 , G06F19/3481 , G16H50/50
摘要： A system and method of adapting a radiation therapy treatment plan. The method includes the acts of preparing a treatment plan for a patient, acquiring images of the patient, performing deformable registration of the images, acquiring data relating to a radiation dose delivered to the patient, applying a biological model relating the radiation dose delivered and a patient effect, and adapting the radiation therapy treatment plan based on the deformable registration and the biological model.
摘要翻译：适应放射治疗治疗计划的系统和方法。该方法包括为患者准备治疗计划的动作，获取患者的图像，执行图像的可变形登记，获取与递送给患者的辐射剂量有关的数据，应用与所传送的辐射剂量有关的生物模型和患者效应，并根据可变形登记和生物模型适应放射治疗计划。

10. 发明申请

US20070041500A1 RADIATION THERAPY IMAGING AND DELIVERY UTILIZING COORDINATED MOTION OF GANTRY AND COUCH 有权
标题翻译：辐射治疗与运送利用运动协调运动
公开(公告)号：US20070041500A1
公开(公告)日：2007-02-22
申请号：US11459161
申请日：2006-07-21
申请人： Gustavo Olivera , Thomas Mackie , Kenneth Ruchala , Paul Reckwerdt , John Hughes , Jeffrey Kapatoes , Eric Schnarr , Weiguo Lu , Eric Schloesser , Gerald Fordyce , Tim Holzmann
发明人： Gustavo Olivera , Thomas Mackie , Kenneth Ruchala , Paul Reckwerdt , John Hughes , Jeffrey Kapatoes , Eric Schnarr , Weiguo Lu , Eric Schloesser , Gerald Fordyce , Tim Holzmann
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61N5/1049 , A61N5/1069
摘要： A system and method of delivering a radiation therapy treatment plan to a patient. The treatment plan is delivered using a radiation therapy system including a moveable support for supporting a patient, a gantry moveable relative to the support and supporting a radiation source and multi-leaf collimator for modulating the radiation source. The support and gantry are moved during delivery of the treatment plan.
摘要翻译：将辐射治疗计划递送给患者的系统和方法。治疗计划使用包括用于支撑患者的可移动支撑物的放射治疗系统，相对于支撑件可移动的支架并支撑用于调制辐射源的辐射源和多叶准直器的放射治疗系统。在治疗计划的交付过程中移动支撑和支架。

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