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1. 发明授权

US10563246B2 Microfluidic device for production and collection of droplets of a fluid 有权
公开(公告)号：US10563246B2
公开(公告)日：2020-02-18
申请号：US13876960
申请日：2011-10-03
申请人： Marie-Claude Potier , Patrick Tabeling , Luce Dauphinot , Nadege Bois , Fabrice Monti , Pascaline Mary
发明人： Marie-Claude Potier , Patrick Tabeling , Luce Dauphinot , Nadege Bois , Fabrice Monti , Pascaline Mary
IPC分类号： C12Q1/68 , C12Q1/6806 , C12Q1/6813 , C12Q1/6844
摘要： A microfluidic device and method for producing and collecting single droplets of a first fluid, the device including a microfluidic platform having at least a droplet microchannel wherein is produced a flow of single droplets of the first fluid dispersed in a second fluid immiscible with the first fluid, the droplet microchannel having at least one inlet extremity and at least one outlet extremity for distributing the flow of droplets, the device further including: a collection device including a plurality of receiving areas adapted to collect at least one of the droplets, elements for changing the relative position of the collection device and the outlet of the microfluidic platform, elements for controlling the flow of droplets, and elements for synchronizing the flow of droplets at the outlet of the droplet microchannel and the relative movement of the collection device with regards to the microfluidic platform.

2. 发明申请

US20120121516A1 Emulsion Activatable by Ultrasounds and Method for Producing Same 审中-公开
标题翻译：超声波激活的乳液及其生产方法
公开(公告)号：US20120121516A1
公开(公告)日：2012-05-17
申请号：US13382745
申请日：2010-07-07
申请人： Patrick Tabeling , Mickael Tanter , Nicolas Pannacci , Olivier Couture , Mathias Fink
发明人： Patrick Tabeling , Mickael Tanter , Nicolas Pannacci , Olivier Couture , Mathias Fink
IPC分类号： A61K49/22 , A61P35/00 , A61K9/14 , A61K31/7088 , B82Y40/00 , B82Y5/00
CPC分类号： A61K9/0019 , A61B8/0833 , A61B8/481 , A61J3/00 , A61K9/0009 , A61K9/1075 , A61K41/0028
摘要： The invention relates to an emulsion that can be activated by ultrasounds, comprising, in an emulsion in an aqueous solution, microparticles having a diameter of less than 10 μm and containing an active agent and a gaseous precursor in a liquid form, encapsulated by a first emulsifier. The microparticles contain nanoparticles smaller than 1 μm, in an emulsion in the gaseous precursor, each nanoparticle comprising an inner liquid that contains the active agent and is encapsulated by a second emulsifier.
摘要翻译：本发明涉及一种能够被超声波激活的乳液，其在水溶液中的乳液中包含直径小于10μm的微粒，并且含有液体形式的活性剂和气体前体，其被第一乳化剂。微粒含有小于1μm的纳米颗粒，在气态前体中的乳液中，每个纳米颗粒包含含有活性剂并由第二乳化剂包封的内部液体。

3. 发明申请

US20130236901A1 MICROFLUIDIC DEVICE FOR PRODUCTION AND COLLECTION OF DROPLETS OF A FLUID 审中-公开
标题翻译：用于生产和收集流体液滴的微流体装置
公开(公告)号：US20130236901A1
公开(公告)日：2013-09-12
申请号：US13876960
申请日：2011-10-03
申请人： Marie-Claude Potier , Patrick Tabeling , Luce Dauphinot , Nadege Bois , Fabrice Monti , Pascaline Mary
发明人： Marie-Claude Potier , Patrick Tabeling , Luce Dauphinot , Nadege Bois , Fabrice Monti , Pascaline Mary
IPC分类号： C12Q1/68
摘要： A microfluidic device and method for producing and collecting single droplets of a first fluid, the device including a microfluidic platform having at least a droplet microchannel wherein is produced a flow of single droplets of the first fluid dispersed in a second fluid immiscible with the first fluid, the droplet microchannel having at least one inlet extremity and at least one outlet extremity for distributing the flow of droplets, the device further including: a collection device including a plurality of receiving areas adapted to collect at least one of the droplets, elements for changing the relative position of the collection device and the outlet of the microfluidic platform, elements for controlling the flow of droplets, and elements for synchronizing the flow of droplets at the outlet of the droplet microchannel and the relative movement of the collection device with regards to the microfluidic platform.
摘要翻译：一种用于产生和收集第一流体的单液滴的微流体装置和方法，该装置包括具有至少液滴微通道的微流体平台，其中产生分散在与第一流体不混溶的第二流体中的第一流体的单液滴流所述液滴微通道具有至少一个入口末端和用于分配液滴流的至少一个出口末端，所述装置还包括：收集装置，其包括适于收集液滴中的至少一个的多个接收区域，用于改变微流体平台的收集装置和出口的相对位置，用于控制液滴流动的元件和用于使液滴微通道出口处的液滴流动同步的元件以及收集装置相对于液滴微通道的相对运动微流体平台。

4. 发明申请

US20090221082A1 Microfluidic Evaporators And Determining Physical And/Or Chemical Properties Of Chemical Compounds Therewith 审中-公开
标题翻译：微流控蒸发器，并确定化学化合物的物理和/或化学性质
公开(公告)号：US20090221082A1
公开(公告)日：2009-09-03
申请号：US12089488
申请日：2006-10-05
申请人： Mathieu Joanicot , Jacques Leng , Armand Ajdari , Patrick Tabeling
发明人： Mathieu Joanicot , Jacques Leng , Armand Ajdari , Patrick Tabeling
IPC分类号： G01N33/44 , G01N33/00 , G01N1/10 , G01N21/00
CPC分类号： B01D61/362 , B01J2219/00286 , B01J2219/00585 , B01J2219/00702 , B01J2219/0072 , B01J2219/00756 , B01L3/06 , B01L3/502723 , B01L2200/0678 , B01L2300/0825 , B01L2300/0887 , Y10T436/2575
摘要： Microfluidic devices having a membrane allowing evaporation are useful for conducting a measurement or observation of compounds introduced therein.
摘要翻译：具有允许蒸发的膜的微流体装置可用于对其中引入的化合物进行测量或观察。

5. 发明授权

US06902313B2 Micro chaotic mixer 有权
标题翻译：微混沌混合器
公开(公告)号：US06902313B2
公开(公告)日：2005-06-07
申请号：US09923477
申请日：2001-08-07
申请人： Chih-Ming Ho , Patrick Tabeling , Yi-Kuen Lee , Joanne Helene Deval
发明人： Chih-Ming Ho , Patrick Tabeling , Yi-Kuen Lee , Joanne Helene Deval
IPC分类号： B01F5/06 , B01F13/00 , B81B1/00
CPC分类号： B01F13/0076 , B01F5/0618 , B01F5/0646 , B01F5/065 , B01F5/0654 , B01F5/0655 , B01F13/0001 , B01F13/0005 , B01F13/0006 , B01F13/0077 , Y10S366/01 , Y10S366/02
摘要： A micro mixer for use in a microdevice which utilizes time-varying force fields to induce bulk fluid and/or sample component motion leading to homogenization of sample components. Time-varying force fields employed includes at least one of a physical displacement field, electrical field, pressure field or magnetic field to generate transverse forces which induce the mixing of samples within the micro mixer.
摘要翻译：用于微型装置的微型混合器，其利用时变力场来诱导体液和/或样品组分运动，导致样品组分的均匀化。使用的时变力场包括物理位移场，电场，压力场或磁场中的至少一个，以产生诱导微混合器内的样品混合的横向力。

6. 发明申请

US20060008382A1 Microfluidic system for chemical analysis 有权
标题翻译：微流控系统进行化学分析
公开(公告)号：US20060008382A1
公开(公告)日：2006-01-12
申请号：US10885471
申请日：2004-07-06
申请人： Philippe Salamitou , Joyce Wong , Bhavani Raghuraman , Jagdish Shah , Ronald Van Hal , Robert Schroeder , Patrick Tabeling
发明人： Philippe Salamitou , Joyce Wong , Bhavani Raghuraman , Jagdish Shah , Ronald Van Hal , Robert Schroeder , Patrick Tabeling
IPC分类号： G01N21/00
CPC分类号： B01L3/502715 , B01L3/502707 , B01L3/50273
摘要： A microfluidic system for performing fluid analysis is described having: (a) a submersible housing having a fluid analysis means and a power supply to provide power to said system; and (b) a substrate for receiving a fluid sample, having embedded therein a fluid sample inlet, a reagent inlet, a fluid sample outlet, and a mixing region in fluid communication with the fluid sample inlet, the reagent inlet, and the fluid sample outlet, and wherein the substrate includes a fluid drive means for moving the fluid sample through the substrate, and wherein the substrate interconnects with the housing. At least a portion of the fluid analysis means may be embedded in the substrate.
摘要翻译：描述了一种用于执行流体分析的微流体系统，其具有：（a）具有流体分析装置的潜水壳体和向所述系统提供动力的电源; （b）用于接收流体样品的基板，其中嵌入有流体样品入口，试剂入口，流体样品出口和与流体样品入口，试剂入口和流体样品流体连通的混合区域出口，并且其中所述基板包括用于使所述流体样品通过所述基板移动的流体驱动装置，并且其中所述基板与所述壳体相互连接。流体分析装置的至少一部分可以嵌入衬底中。

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