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1. 发明授权

US09339022B2 Injector nozzle 有权
标题翻译：喷油嘴
公开(公告)号：US09339022B2
公开(公告)日：2016-05-17
申请号：US14565971
申请日：2014-12-10
申请人： Oliver Buck , Thomas Schenk
发明人： Oliver Buck , Thomas Schenk
IPC分类号： A62C31/02 , B05B1/00 , A01M7/00 , B05B7/04 , B05B7/24 , B05B15/00
CPC分类号： A01M7/005 , B05B1/00 , B05B7/0408 , B05B7/2443 , B05B15/16
摘要： An injector nozzle for intake of liquids, including an injector chamber, a liquid inlet opening for an overpressured carrier liquid, the inlet opening issuing into the injector chamber, a liquid intake opening for a liquid to be drawn in, the intake opening issuing into the injector chamber, wherein downstream of the liquid inlet opening, the injector chamber has a first section conically enlarging in the flow direction and a second section conically enlarging in the flow direction, wherein the second conical section adjoins the first conical section and the second conical section has a greater cone angle than the first conical section.
摘要翻译：用于吸入液体的喷射器喷嘴，包括喷射室，用于超压载液的液体入口，进入喷射室的入口开口，用于待吸入的液体的进液口，注射器腔室，其中在所述液体入口开口的下游，所述注射器腔室具有沿流动方向锥形扩大的第一部分和在流动方向上锥形扩大的第二部分，其中所述第二锥形部分邻接所述第一锥形部分和所述第二锥形部分具有比第一锥形部分更大的锥角。

2. 发明申请

US20140296609A1 Layer Structure for Epidermal Radionuclide Therapy 有权
标题翻译：表皮放射性核素治疗的层结构
公开(公告)号：US20140296609A1
公开(公告)日：2014-10-02
申请号：US14123578
申请日：2012-06-06
申请人： Maria Desantis , Oliver Buck , Cesidio Cipriani
发明人： Maria Desantis , Oliver Buck , Cesidio Cipriani
IPC分类号： A61N5/10
CPC分类号： A61N5/1029
摘要： Disclosed is a layer structure for epidermal radionuclide therapy (brachytherapy) of a patient comprising, from a patient's view, a proximal adherent layer for applying the layer structure on the skin surface to be treated of a patient; a flexible, transparent carrier layer that from a patient's view is located in a distal direction on the adherent layer; and at least one radionuclide-containing emission layer located on the carrier layer, the adherent layer and the carrier layer with regard to their components and thickness being formed such that they are essentially transparent for β and γ radiation. The layer structure is suited particularly for radiotherapeutic treatment of the basal-cell carcinoma (BCC) and the squamous cell carcinoma (SCC). With the aid of the layer structure, geometrically complex skin lesions caused by a tumor, as occurring e.g. on the outer edge of the auricle, may be treated easily.
摘要翻译：公开了一种患者的表皮放射性核素治疗（近距离放射治疗）的层结构，包括从患者的角度来看，用于将层结构施加在待治疗的患者的皮肤表面上的近端粘附层; 柔性透明的载体层，其从患者的视角位于粘附层上的远侧方向上; 以及位于载体层上的至少一个含放射性核素的发射层，相对于它们的组分和厚度形成的粘合层和载体层，使得它们基本上是透明的。和γ辐射。该层结构特别适用于基底细胞癌（BCC）和鳞状细胞癌（SCC）的放射治疗治疗。借助于层结构，由肿瘤引起的几何复杂的皮肤损伤，例如发生。在耳廓的外缘，可以容易地治疗。

3. 发明申请

US20090243283A1 System and Method for Closed, Drip-Free and Secure Transfer of Fluids 有权
标题翻译：液体封闭，无滴漏和安全转移的系统和方法
公开(公告)号：US20090243283A1
公开(公告)日：2009-10-01
申请号：US12299604
申请日：2007-05-02
申请人： Michael Schilp , Oliver Buck
发明人： Michael Schilp , Oliver Buck
IPC分类号： F16J15/00 , F16L35/00
CPC分类号： A61J1/20 , A61M39/04 , A61M39/10 , A61M2039/1072
摘要： A connector for enclosed, drip-free, and safe transfer of fluids, comprising an opening and a closure means adapted to close the opening and to establish a tight joint with another connector for transferring fluid between the connectors, further comprising a tube section arranged inside the connector and adapted to be advanced through the opening and out of the connector.
摘要翻译：一种用于封闭，无滴漏和安全转移流体的连接器，包括开口和闭合装置，其适于闭合开口并与另一连接器建立紧密接头，用于在连接器之间输送流体，还包括布置在内部的管部分连接器并且适于通过开口前进穿过连接器。

4. 发明申请

US20080140046A1 Integrated Pharmaceutical Production, Quality, Assurance, and Safety System (Iqs) 有权
标题翻译：综合药品生产，质量保证和安全系统（Iqs）
公开(公告)号：US20080140046A1
公开(公告)日：2008-06-12
申请号：US11793467
申请日：2006-04-04
申请人： Oliver Buck , Christoph Ehlers , Tuomo Nikula , Michael Schilp
发明人： Oliver Buck , Christoph Ehlers , Tuomo Nikula , Michael Schilp
IPC分类号： A61B19/00
CPC分类号： A61J3/00 , A61J1/20
摘要： A therapy module for providing a diagnostic or therapeutic substance combination, including at least two containers adapted to be interconnected for taking up at least one substance, and means or part of a means for supplying a quantity of the at least one substance from one of the containers into another container of the therapy module.
摘要翻译：一种用于提供诊断或治疗物质组合的治疗模块，包括至少两个适于互连以容纳至少一种物质的容器，以及用于从所述至少一种物质之一中提供一种物质的装置的一部分容器进入治疗模块的另一容器。

5. 发明申请

US20070076834A1 Radium Target and method for producing it 审中-公开
标题翻译：镭靶及其生产方法
公开(公告)号：US20070076834A1
公开(公告)日：2007-04-05
申请号：US11402143
申请日：2006-04-11
申请人： Josue Moreno Bermudez , Andreas Turler , Richard Henklemann , Mark Harfensteller , Ernst Huenges , Michael Schilp , Oliver Buck , Mauritius Geerlings
发明人： Josue Moreno Bermudez , Andreas Turler , Richard Henklemann , Mark Harfensteller , Ernst Huenges , Michael Schilp , Oliver Buck , Mauritius Geerlings
IPC分类号： G21G1/10
CPC分类号： C25D3/54 , A61K51/1282
摘要： The present invention relates to a radium target as well as to a method for producing it for the production of radionuclides by means of accelerated protons, wherein an electrodeposition of radium out of at least one aqueous organic solution containing 226Ra ions is carried out on at least one aluminium surface, wherein the aluminium surface is connected as cathode. With the 226Ra target according to the present invention, 225Ac/213Bi, which can be used, for example, for radioimmunotherapy for cancer treatment, can be produced continuously and in sufficient quantities at a reasonable price.
摘要翻译：本发明涉及一种镭靶及其生产用于通过加速质子制备放射性核素的方法，其中，将至少一种含有有机溶液的含镉电沉积在含有在至少一个铝表面上进行Ra离子，其中铝表面作为阴极连接。使用根据本发明的＆lt; 226＆gt;＆lt; 226＆gt;目标，可以使用例如用于癌症的放射免疫治疗的Bi2B2 Bi2B2 Bi 处理，可以以合理的价格连续生产和数量充足。

6. 发明授权

US10350433B2 Layer structure for epidermal radionuclide therapy 有权
公开(公告)号：US10350433B2
公开(公告)日：2019-07-16
申请号：US14123578
申请日：2012-05-16
申请人： Maria Desantis , Oliver Buck , Cesidio Cipriani
发明人： Maria Desantis , Oliver Buck , Cesidio Cipriani
IPC分类号： A61N5/10
摘要： Disclosed is a layer structure for epidermal radionuclide therapy (brachytherapy) of a patient comprising, from a patient's view, a proximal adherent layer for applying the layer structure on the skin surface to be treated of a patient; a flexible, transparent carrier layer that from a patient's view is located in a distal direction on the adherent layer; and at least one radionuclide-containing emission layer located on the carrier layer, the adherent layer and the carrier layer with regard to their components and thickness being formed such that they are essentially transparent for β and γ radiation. The layer structure is suited particularly for radiotherapeutic treatment of the basal-cell carcinoma (BCC) and the squamous cell carcinoma (SCC). With the aid of the layer structure, geometrically complex skin lesions caused by a tumor, as occurring e.g. on the outer edge of the auricle, may be treated easily.

7. 发明授权

US09527100B2 Injector nozzle 有权
标题翻译：喷油嘴
公开(公告)号：US09527100B2
公开(公告)日：2016-12-27
申请号：US14661733
申请日：2015-03-18
申请人： Oliver Buck , Thomas Schenk , Joaquim Gomes-Alves
发明人： Oliver Buck , Thomas Schenk , Joaquim Gomes-Alves
IPC分类号： B05B7/04 , B05B15/06 , B05B1/04 , B05B1/14
CPC分类号： B05B15/658 , B05B1/046 , B05B1/14 , B05B7/0425
摘要： An injector nozzle having a housing, an interior space of the housing being defined in sections by a housing wall, and having an injector component arranged in the interior space of the housing at least in sections, wherein the housing wall has at least one through hole, the at least one through hole being appropriate for a human finger to reach in, at least in sections, and wherein the injector component has at least one handle portion, which handle portion is accessible via the through hole.
摘要翻译：一种具有壳体的喷射器喷嘴，所述壳体的内部空间由壳体壁部分地限定，并且具有至少部分地布置在所述壳体的内部空间中的喷射器部件，其中所述壳体壁具有至少一个通孔所述至少一个通孔适于人的手指到达至少部分，并且其中所述注射器部件具有至少一个手柄部分，所述手柄部分可以经由所述通孔接近。

8. 发明申请

US20150157005A1 INJECTOR NOZZLE 有权
标题翻译：喷嘴喷嘴
公开(公告)号：US20150157005A1
公开(公告)日：2015-06-11
申请号：US14565971
申请日：2014-12-10
申请人： Oliver BUCK , Thomas SCHENK
发明人： Oliver BUCK , Thomas SCHENK
IPC分类号： A01M7/00 , B05B1/00
CPC分类号： A01M7/005 , B05B1/00 , B05B7/0408 , B05B7/2443 , B05B15/16
摘要： An injector nozzle for intake of liquids, including an injector chamber, a liquid inlet opening for an overpressured carrier liquid, the inlet opening issuing into the injector chamber, a liquid intake opening for a liquid to be drawn in, the intake opening issuing into the injector chamber, wherein downstream of the liquid inlet opening, the injector chamber has a first section conically enlarging in the flow direction and a second section conically enlarging in the flow direction, wherein the second conical section adjoins the first conical section and the second conical section has a greater cone angle than the first conical section.
摘要翻译：用于吸入液体的喷射器喷嘴，包括喷射室，用于超压载液的液体入口，进入喷射室的入口开口，用于待吸入的液体的进液口，注射器腔室，其中在所述液体入口开口的下游，所述注射器腔室具有沿流动方向锥形扩大的第一部分和在流动方向上锥形扩大的第二部分，其中所述第二锥形部分邻接所述第一锥形部分和所述第二锥形部分具有比第一锥形部分更大的锥角。

9. 发明授权

US08734315B2 Apparatus and method for filling a medical instrument with a radioactive substance 有权
标题翻译：用放射性物质填充医疗器械的装置和方法
公开(公告)号：US08734315B2
公开(公告)日：2014-05-27
申请号：US12526429
申请日：2008-02-01
申请人： Michael Schilp , Nikula Tuomo , Oliver Buck
发明人： Michael Schilp , Nikula Tuomo , Oliver Buck
IPC分类号： A61M36/06 , A61M36/08
CPC分类号： A61M5/1785 , A61M5/1782 , G21F5/018 , Y10T137/0318 , Y10T137/7043
摘要： An apparatus for filling a medical instrument with a radioactive substance, said apparatus including a housing designed to receive a syringe and at least part of a medical instrument and to shield against radioactive radiation, further including a means to take up a receptacle for a radioactive substance.
摘要翻译：一种用于用放射性物质填充医疗器械的装置，所述装置包括设计成容纳注射器和至少部分医疗器械并防止放射性辐射的壳体，还包括用于吸收放射性物质的容器的装置。

10. 发明申请

US20130006033A1 APPLICATOR FOR APPLYING A RADIOACTIVE SUBSTANCE TO A BIOLOGICAL TISSUE 有权
标题翻译：向生物组织施用放射性物质的申请人
公开(公告)号：US20130006033A1
公开(公告)日：2013-01-03
申请号：US13511614
申请日：2010-11-16
申请人： Cesidio Cipriani , Maria Desantis , Max Bichlmaier , Siegfried Förg , Tuomo Kaarlo Nikula , Mark Harfensteller , Oliver Buck
发明人： Cesidio Cipriani , Maria Desantis , Max Bichlmaier , Siegfried Förg , Tuomo Kaarlo Nikula , Mark Harfensteller , Oliver Buck
IPC分类号： A61M36/00
CPC分类号： A61N5/1001 , A61N5/10 , A61N2005/1021 , G21F3/00
摘要： An applicator for applying a radioactive substance to a biological tissue, the applicator comprising a container for receiving the radioactive substance; an application device connectable to the container, by which the substance compound can be applied to the tissue; and at least a part of a conveying device by which the radioactive substance can be supplied from the container into the application device when the application device has been connected to the container.
摘要翻译：一种用于将放射性物质施加到生物组织的施加器，所述施用器包括用于接收所述放射性物质的容器; 可连接到容器的施用装置，物质化合物可以通过其施加到组织; 以及输送装置的至少一部分，当所述施加装置已经连接到所述容器时，可以通过所述输送装置将所述放射性物质从所述容器供应到所述施加装置中。

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