会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明授权
    • Space heating element having a ceramic body with an electrically
resistive coating thereon
    • 空间加热元件,其上具有电阻涂层的陶瓷体
    • US4833300A
    • 1989-05-23
    • US131856
    • 1987-12-11
    • Martin BardGottfried Cremer
    • Martin BardGottfried Cremer
    • F24D13/02H05B3/28
    • H05B3/283F24D13/022H05B3/286Y02B30/26
    • An electrical space heating element having a ceramic body which is provided on the side facing away from the space to be heated with an electrically resistive coating. The space heating element provides a high thermal yield while consuming little electrical power and may be used as an element of design for the periphery of a room. The space heating element may be installed in such a way so that no channels are formed which might force air currents to circulate in the room to be heated. The electrically resistive coating is a layer of a carrier impregnated with nonmetallic particles which have a large specific area, are electrically conductive, and do not substantially vary the electrical conductivity at higher temperatures. The carrier in which the nonmetallic particles are embedded has no greater than poor electrical conductivity. The electrically resistive coating is applied in such a way that it has uniform electrical and thermal conductivity.
    • 一种电气空间加热元件,其具有陶瓷体,该陶瓷体设置在背离待加热空间的一侧,并具有电阻涂层。 空间加热元件提供高的热收率,同时消耗很少的电力,并且可以用作室内外围设计的元件。 空间加热元件可以以这样的方式安装,使得不形成可能迫使气流在要加热的房间中循环的通道。 电阻涂层是浸渍有非金属颗粒的载体层,其具有大比表面积,导电性,并且在较高温度下基本上不改变导电性。 其中嵌入非金属颗粒的载体不大于差的导电性。 以这样的方式施加电阻涂层,使得其具有均匀的导电和导热性。
    • 4. 发明授权
    • Sterol .DELTA.14 reductase screen
    • Sterol DELTA 14还原酶屏
    • US5591576A
    • 1997-01-07
    • US107348
    • 1993-08-16
    • Margaret H. K. LaiDonald R. KirschMartin Bard
    • Margaret H. K. LaiDonald R. KirschMartin Bard
    • C12N9/02C12N15/53C12Q1/18C12Q1/26C12N15/63C12Q1/02C12Q1/68
    • C12N9/001C12Q1/18C12Q1/26C12Y103/0107
    • A binary assay identifies agents that inhibit sterol .DELTA.14 reductase involved in ergosterol biosynthesis. In the primary screen, sterol .DELTA.14 reductase inhibition by a test sample is assayed by adding the test sample to a culture of Neurospora crassa having an erg-3 mutation and also to a culture of a strain having an erg-1 mutation, comparing the extent of growth inhibition after incubation in the two cultures, and identifying as positives those samples that show growth inhibition in the erg-3 culture exceeding that in the erg-1 culture. In the secondary screen, samples that test positive in the primary screen are reassayed by adding the test sample to a culture of a Saccharomyces cerevisiae strain into which has been introduced multiple copies of a gene encoding sterol .DELTA.14 reductase and also to a strain of S. cerevisiae that does not have the introduced gene; positive samples are identified after incubation by observation that growth inhibition in the culture having no introduced reductase gene exceeds growth inhibition in the culture having the introduced reductase gene. In preferred embodiments, a known inhibitor of sterol .DELTA.14 reductase is employed in solidified media in both the primary and the secondary screens, resulting in an assay that is highly sensitive and specific for the detection of sterol .DELTA.14 reductase inhibitors.
    • 二元测定法鉴定了抑制参与麦角固醇生物合成的甾醇DELTA14还原酶的药剂。 在主筛网中,通过将测试样品加入到具有erg-3突变的粗糙脉孢菌培养物中,并将其与具有erg-1突变的菌株的培养物进行比较,来测定测试样品的固醇DELTA 14还原酶抑制 在两种培养物中孵育后的生长抑制程度,并且鉴定出在erg-3培养物中显示生长抑制的样品超过erg-1培养物中的那些样品的阳性。 在次级屏幕中,通过将测试样品加入到已经引入了多拷贝的编码固醇DELTA14还原酶的基因的Saccharomyces cerevisiae菌株的培养物中,并且还添加到S的菌株 没有引入基因的酿酒酵母; 通过观察,通过观察到没有引入的还原酶基因的培养物中的生长抑制超过在具有引入的还原酶基因的培养物中的生长抑制的情况下,鉴定阳性样品。 在优选的实施方案中,在初级和次级筛中的固化培养基中使用已知的甾醇DELTA 14还原酶抑制剂,导致对检测固醇DELTA14还原酶抑制剂具有高度敏感性和特异性的测定。