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1. 发明授权

US08874147B2 Apparatus, method and system of sending and receiving for supporting application-based MMS 有权
标题翻译：发送和接收的设备，方法和系统，用于支持基于应用的彩信
公开(公告)号：US08874147B2
公开(公告)日：2014-10-28
申请号：US11644242
申请日：2006-12-22
申请人： Chun Sheng Chu , Ling Jin , Jun Shen , Pei Sun , Dong Hai Zhai
发明人： Chun Sheng Chu , Ling Jin , Jun Shen , Pei Sun , Dong Hai Zhai
IPC分类号： H04W4/12 , G06Q10/10 , H04L12/58 , H04M1/725
CPC分类号： H04M1/72547 , G06Q10/107 , H04L51/38 , H04W4/12
摘要： Sending apparatus, receiving apparatus, sending method, receiving method and sending and receiving system for supporting application based MMS. The body of an incremental MMS includes a dynamic data section of MMS, a static data indicator associated with the MMS, and a link tag between indicated static data and the dynamic data. The amount of the message quantity transmitted may be reduced because the changed section of the incremental MMS is sent directly via short message channel in dynamic data mode. In turn, the incremental MMS may be sent via short message channel instead of MMS channel due to the reduction of transmitted message, which further reduces the communication cost.
摘要翻译：发送装置，接收装置，发送方法，接收方法以及用于支持基于应用的MMS的发送和接收系统。增量MMS的主体包括MMS的动态数据部分，与MMS相关联的静态数据指示符，以及指示的静态数据与动态数据之间的链接标签。可以减少发送的消息量的量，因为增量MMS的改变部分通过动态数据模式的短消息信道直接发送。反过来，由于传输的消息的减少，增量MMS可以通过短消息信道而不是MMS信道发送，这进一步降低了通信成本。

2. 发明申请

US20110251266A1 APTAMER FOR NGF AND USE THEREOF 审中-公开
标题翻译：用于NGF的APTAMER及其用途
公开(公告)号：US20110251266A1
公开(公告)日：2011-10-13
申请号：US13120650
申请日：2009-09-18
申请人： Ling Jin , Shin Miyakawa , Masatoshi Fujiwara , Yoshikazu Nakamura , Hisanao Hiramatsu
发明人： Ling Jin , Shin Miyakawa , Masatoshi Fujiwara , Yoshikazu Nakamura , Hisanao Hiramatsu
IPC分类号： A61K31/7088 , C07H21/04 , A61P29/00 , G01N33/566 , C07K1/14 , C07H21/02 , C12N9/96
CPC分类号： C12N15/115 , C07K1/22 , C12N2310/16
摘要： Provided are an aptamer having an inhibitory activity against NGF; a complex containing an aptamer having a binding activity or inhibitory activity against NGF and a functional substance (e.g., affinity substances, labeling substances, enzymes, drug delivery vehicles, drugs and the like); a medicament, a diagnostic agent, a labeling agent and the like containing an aptamer having a binding activity or inhibitory activity against NGF, or a complex containing the aptamer and the functional substance; and the like.
摘要翻译：提供对NGF具有抑制活性的适体; 含有对NGF和功能性物质（例如亲和性物质，标记物质，酶，药物输送载体，药物等）具有结合活性或抑制活性的适体的复合物; 含有对NGF具有结合活性或抑制活性的适体的药剂，诊断剂，标记试剂等，或含有适体和功能性物质的复合物; 等等。

3. 发明授权

US07590540B2 Method and system for statistic-based distance definition in text-to-speech conversion 有权
标题翻译：在文本转语音转换中基于统计的距离定义的方法和系统
公开(公告)号：US07590540B2
公开(公告)日：2009-09-15
申请号：US11239500
申请日：2005-09-29
申请人： Wei Z W Zhang , Xi Jun Ma , Ling Jin , Hai Xin Chai
发明人： Wei Z W Zhang , Xi Jun Ma , Ling Jin , Hai Xin Chai
IPC分类号： G10L13/08
CPC分类号： G10L13/10 , G10L13/04
摘要： A method for distance definition in a text-to-speech conversion system by applying Gaussian Mixture Model (GMM) to a distance definition. According to an embodiment, the text that is to be subjected to text-to-speech conversion is analyzed to obtain a text with descriptive prosody annotation; clustering is performed for samples in the obtained text; and a GMM model is generated for each cluster, to determine the distance between the sample and the corresponding GMM model.
摘要翻译：一种通过将高斯混合模型（GMM）应用于距离定义的文本到语音转换系统中的距离定义的方法。根据一个实施例，分析要进行文本到语音转换的文本以获得具有描述性韵律注释的文本; 对获取的文本中的样本进行聚类; 并为每个群集生成一个GMM模型，以确定样本与相应的GMM模型之间的距离。

4. 发明申请

US20080270352A1 MODIFYING ENTRY NAMES IN DIRECTORY SERVER 有权
标题翻译：修改目录服务器中的入口名称
公开(公告)号：US20080270352A1
公开(公告)日：2008-10-30
申请号：US12109556
申请日：2008-04-25
申请人： CHEN WANG , Zhi Guo Gao , Ling Jin , Xiao Yan Chen
发明人： CHEN WANG , Zhi Guo Gao , Ling Jin , Xiao Yan Chen
IPC分类号： G06F17/30
CPC分类号： G06F17/30589 , H04L29/12084 , H04L29/12132 , H04L29/12594 , H04L61/1523 , H04L61/1552 , H04L61/30
摘要： The present invention provides a system and a computer-implemented method for modifying an entry name in a directory database. The method comprises the steps of: modifying, in response to a request for modifying operation of entry names, entry mapping information in accordance with the modification that is requested for modifying operation of entry names, wherein each piece of entry mapping information is used for indicating the correspondence relation between pre-modification entry name information and post-modification entry name information; asynchronously performing modifying operation of a corresponding entry name in accordance with respective pieces of entry mapping information when a predetermined condition for updating the directory database is met.
摘要翻译：本发明提供了一种用于修改目录数据库中的条目名称的系统和计算机实现的方法。该方法包括以下步骤：响应于修改条目名称的操作的请求，修改根据修改条目映射信息，其中每个条目映射信息被用于指示预修改条目名称信息和修改后条目名称信息之间的对应关系; 当满足用于更新目录数据库的预定条件时，根据各条目条目映射信息异步执行相应条目名称的修改操作。

5. 发明申请

US20130052176A1 APTAMER FOR NGF AND USE THEREOF 有权
标题翻译：用于NGF的APTAMER及其用途
公开(公告)号：US20130052176A1
公开(公告)日：2013-02-28
申请号：US13636974
申请日：2011-03-24
申请人： Yoshikazu Nakamura , Ling Jin , Hisanao Hiramatsu
发明人： Yoshikazu Nakamura , Ling Jin , Hisanao Hiramatsu
IPC分类号： C07H21/02 , A61P29/00 , A61K38/43 , A61K31/7105 , C12N9/96 , A61K31/7088
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/3515
摘要： Provided is a higher quality aptamer having a binding activity to NGF.An aptamer binding to NGF, which satisfies the following (1) and (2): (1) containing the sequence represented by UGAAARAAACC (SEQ ID NO: 64) or CGAAMRAAACU (SEQ ID NO: 65), and (2) having a base length of not more than 73.
摘要翻译：提供了对NGF具有结合活性的更高质量的适体。与NGF结合的适体，其满足以下（1）和（2）：（1），含有由UGAAARAAACC（SEQ ID NO：64）或CGAAMRAAACU（SEQ ID NO：65）表示的序列，和（2）具有基地长度不超过73。

6. 发明申请

US20120165401A1 APTAMER FOR CHYMASE, AND USE THEREOF 有权
标题翻译：乙酰胺和其使用的APTAMER
公开(公告)号：US20120165401A1
公开(公告)日：2012-06-28
申请号：US13377201
申请日：2010-06-11
申请人： Yoshikazu Nakamura , Ling Jin , Satoko Yamazaki , Hisako Ikeda , Masahiro Muraguchi
发明人： Yoshikazu Nakamura , Ling Jin , Satoko Yamazaki , Hisako Ikeda , Masahiro Muraguchi
IPC分类号： A61K31/7105 , C12N9/96 , A61P43/00 , C12N9/64 , A61P9/00 , C07H21/02 , C12Q1/68
CPC分类号： C12N15/115 , A61K31/7105 , C12N2310/16 , C12N2310/322 , C12Y304/21039 , C12N2310/3533
摘要： Provided are an aptamer bound to chymase to inhibit activity of chymase; an aptamer containing a nucleotide sequence represented by X1GAUAGAN1N2UAAX2 wherein X1 and X2 are the same or different and each is A or G, and N1 and N2 are the same or different and each is A, G, C, U or T; a complex containing the aptamer and a functional substance (e.g., affinity substance, labeling substance, enzyme, drug delivery medium, drug and the like); a pharmaceutical or a reagent containing the aptamer or complex; a detection and a purification methods of chymase using the aptamer or complex and the like.
摘要翻译：提供与胃促胰酶结合以抑制胃促胰酶的活性的适体; 含有由X1GAUAGAN1N2UAAX2表示的核苷酸序列的适体，其中X1和X2相同或不同，分别为A或G，N1和N2相同或不同，分别为A，G，C，U或T; 含有适体和功能性物质（例如亲和性物质，标记物质，酶，药物传递介质，药物等）的复合物; 含有适体或复合物的药物或试剂; 使用适体或复合物等的胃促胰酶的检测和纯化方法。

7. 发明申请

US20100003794A1 METHOD FOR DEFECT REDUCTION FOR MEMORY CELL CAPACITORS 有权
标题翻译：用于存储单元电容器的减少缺陷的方法
公开(公告)号：US20100003794A1
公开(公告)日：2010-01-07
申请号：US12259138
申请日：2008-10-27
申请人： Ling Jin , Dah Cheng Lin , Chin Hsing Yu , Meng Jan Cherng , Huan Sung Fu
发明人： Ling Jin , Dah Cheng Lin , Chin Hsing Yu , Meng Jan Cherng , Huan Sung Fu
IPC分类号： H01L21/8242
CPC分类号： H01L28/91 , H01L27/10852 , H01L27/10894
摘要： A method for forming a cylindrical stack capacitor structure. A semiconductor substrate is provided. Storage node structures are formed in a memory cell region. A dielectric layer is formed overlying the storage node structures. A patterning and a first etching process expose the storage nodes. A polysilicon layer and a rugged polysilicon layer are formed overlying the exposed storage nodes. The memory cell region is masked, exposing a peripheral region. A chemical dry etch process removes the rugged polysilicon and the polysilicon layers in the peripheral region. The rugged polysilicon and the polysilicon layers are planarized followed by a dielectric recess. The resulting cylindrical stack capacitor structures are substantially free of defects from rugged polysilicon remaining in the peripheral region thereby improving device yield and process window.
摘要翻译：一种形成圆柱形堆叠电容器结构的方法。提供半导体衬底。存储节点结构形成在存储单元区域中。在存储节点结构上形成介电层。图案化和第一蚀刻工艺暴露存储节点。在暴露的存储节点上形成多晶硅层和坚固的多晶硅层。掩蔽存储单元区域，暴露外围区域。化学干蚀刻工艺去除了外围区域中的坚固的多晶硅和多晶硅层。凹凸多晶硅和多晶硅层被平坦化，随后是电介质凹陷。所得到的圆柱形堆叠电容器结构基本上没有残留在外围区域中的粗糙多晶硅的缺陷，从而提高了器件产量和工艺窗口。

8. 发明授权

US09175292B2 Aptamer for NGF and use thereof 有权
标题翻译： NGF的适配器及其用途
公开(公告)号：US09175292B2
公开(公告)日：2015-11-03
申请号：US13636974
申请日：2011-03-24
申请人： Yoshikazu Nakamura , Ling Jin , Hisanao Hiramatsu
发明人： Yoshikazu Nakamura , Ling Jin , Hisanao Hiramatsu
IPC分类号： C07H21/02 , A61K48/00 , C12N15/115
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/3515
摘要： Provided is a higher quality aptamer having a binding activity to NGF.An aptamer binding to NGF, which satisfies the following (1) and (2): (1) containing the sequence represented by UGAAARAAACC (SEQ ID NO: 64) or CGAAMRAAACU (SEQ ID NO: 65), and (2) having a base length of not more than 73.
摘要翻译：提供了对NGF具有结合活性的更高质量的适体。与NGF结合的适体，其满足以下（1）和（2）：（1），含有由UGAAARAAACC（SEQ ID NO：64）或CGAAMRAAACU（SEQ ID NO：65）表示的序列，和（2）具有基地长度不超过73。

9. 发明授权

US09094806B2 MMS system to support message based applications 有权
标题翻译： MMS系统支持基于消息的应用
公开(公告)号：US09094806B2
公开(公告)日：2015-07-28
申请号：US13611364
申请日：2012-09-12
申请人： Chun Sheng Chu , Ling Jin , Jun Shen , Pei Sun , Dong Hai Zhai
发明人： Chun Sheng Chu , Ling Jin , Jun Shen , Pei Sun , Dong Hai Zhai
IPC分类号： H04W4/12 , H04W4/14 , A45F4/06 , A47C7/62 , A47C31/11 , A47G9/06 , A45F3/02
CPC分类号： H04W4/12 , A45F3/02 , A45F4/06 , A47C7/386 , A47C31/11 , A47G9/062 , H04W4/14
摘要： Sending apparatus, receiving apparatus, sending method, receiving method and sending and receiving system for supporting application based MMS. The body of an incremental MMS includes a dynamic data section of MMS, a static data indicator associated with the MMS, and a link tag between indicated static data and the dynamic data. The amount of the message quantity transmitted may be reduced because the changed section of the incremental MMS is sent directly via short message channel in dynamic data mode. In turn, the incremental MMS may be sent via short message channel instead of MMS channel due to the reduction of transmitted message, which further reduces the communication cost.
摘要翻译：发送装置，接收装置，发送方法，接收方法以及用于支持基于应用的MMS的发送和接收系统。增量MMS的主体包括MMS的动态数据部分，与MMS相关联的静态数据指示符，以及指示的静态数据与动态数据之间的链接标签。可以减少发送的消息量的量，因为增量MMS的改变部分通过动态数据模式的短消息信道直接发送。反过来，由于传输的消息的减少，增量MMS可以通过短消息信道而不是MMS信道发送，这进一步降低了通信成本。

10. 发明授权

US08252923B2 Peptidomimetic protease inhibitors 失效
标题翻译：拟肽蛋白酶抑制剂
公开(公告)号：US08252923B2
公开(公告)日：2012-08-28
申请号：US12231982
申请日：2008-09-08
申请人： Robert Edward Babine , Shu-Hui Chen , Jason Eric Lamar , Nancy June Snyder , Xicheng Sun , Mark Joseph Tebbe , Frantz Victor , Q. May Wang , Yvonne Yee Mai Yip , Ivan Collado , Cristina Garcia-Paredes , Raymond Samuel Parker, III , Ling Jin , Deqi Guo , John Irvin Glass
发明人： Robert Edward Babine , Shu-Hui Chen , Jason Eric Lamar , Nancy June Snyder , Xicheng Sun , Mark Joseph Tebbe , Frantz Victor , Q. May Wang , Yvonne Yee Mai Yip , Ivan Collado , Cristina Garcia-Paredes , Raymond Samuel Parker, III , Ling Jin , Deqi Guo , John Irvin Glass
IPC分类号： C07D265/34 , C07D241/08 , C07D275/06 , C07D417/02 , C07D233/32 , C07D403/02 , C07D207/08 , C07D493/14 , C07C229/00
CPC分类号： C07K7/02 , A61K38/07 , A61K38/08 , A61K38/21 , A61K38/212 , A61K38/215 , A61K45/06 , C07D209/02 , C07D209/52 , C07K5/0202 , C07K5/0205 , C07K5/06052 , C07K5/0808 , C07K5/101 , C07K5/1016 , C07K7/06 , C07K14/005 , C12N2770/24222 , Y02P20/55 , A61K2300/00
摘要： The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
摘要翻译：本发明涉及可用作蛋白酶抑制剂的肽模拟化合物，特别是作为丝氨酸蛋白酶抑制剂，更具体地，涉及丙型肝炎NS3蛋白酶抑制剂; 中间体; 它们的制备方法包括对中间体的新型置换步骤。本发明还涉及药物组合物和使用该化合物抑制HCV蛋白酶或治疗患有HCV感染或与感染有关的生理病症的患者的方法。还提供了药物组合，除一种或多种HCV丝氨酸蛋白酶抑制剂外还包含一种或多种表现出抗HCV活性的干扰素和/或一种或多种具有抗HCV活性的化合物和药学上可接受的载体，以及用于治疗或预防的方法使用该组合物的患者中的HCV感染。本发明还涉及用于治疗或预防患者HCV感染的试剂盒或药物包装。

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