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    • 9. 发明授权
    • Two-stage method for preparing polyol fatty acid polyesters
    • 制备多元醇脂肪酸聚酯的两阶段方法
    • US5681948A
    • 1997-10-28
    • US398749
    • 1995-03-06
    • Mark Stuart MillerLeslie George WestRobert Charles DinwoodieRichard S. Silver
    • Mark Stuart MillerLeslie George WestRobert Charles DinwoodieRichard S. Silver
    • C07H1/00C07H13/04C07H13/06C07H13/02
    • C07H13/04C07H13/06
    • A two-stage method for the preparation of polyol fatty acid polyesters is provided. The resulting polyol fatty acid polyesters are very lightly colored (i.e., colorless to slightly yellow) and have a high degree of substitution with fatty acid groups. The first stage of this two-stage method is a solvent-based esterification reaction; the second stage is an essentially solvent-free esterification reaction. In the first stage, a polyol in a solvent (e.g., sucrose in dimethylsulfoxide)) is reacted with fatty acid lower alkyl esters at relatively low temperatures using an alkaline salt catalyst. After the desired degree of esterification is obtained, the resulting partially-esterified polyol fatty acid polyesters and the solvent-containing phase are separated. The separated partially-esterified polyol fatty acid polyesters are further esterified with the same or different fatty acid lower alkyl esters in a second stage with an alkaline salt catalyst using essentially solvent-free, high temperature conditions whereby the degree of substitution is significantly increased. Most of the color bodies and other contaminants capable of producing color are removed with the solvent in the first stage and, therefore, are not present during the higher temperature reaction conditions of the second stage. The resulting polyol fatty acid polyesters, and in particular the sucrose fatty acid polyesters, are especially useful as fat substitutes in food applications and products.
    • 提供了制备多元醇脂肪酸聚酯的两阶段方法。 得到的多元醇脂肪酸聚酯非常浅色(即无色至微黄色)并且具有高脂肪酸基取代度。 这种两步法的第一阶段是溶剂型酯化反应; 第二阶段是基本上无溶剂的酯化反应。 在第一阶段中,使用碱性盐催化剂,在相对较低的温度下,将溶剂中的多元醇(例如二甲基亚砜中的蔗糖))与脂肪酸低级烷基酯反应。 在获得所需的酯化度之后,分离得到的部分酯化的多元醇脂肪酸聚酯和含溶剂的相。 分离的部分酯化的多元醇脂肪酸聚酯在第二阶段中用相同或不同的脂肪酸低级烷基酯进一步用碱性盐催化剂进行酯化,使用基本上无溶剂的高温条件,从而显着提高了取代度。 能够产生颜色的大多数着色体和其它污染物在第一阶段用溶剂除去,因此在第二阶段的较高温度的反应条件下不存在。 所得的多元醇脂肪酸聚酯,特别是蔗糖脂肪酸聚酯,特别适用于食品应用和产品中的脂肪替代物。