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    • 4. 发明授权
    • Method of enriching glucoraphanin in radish seed preparations
    • 萝卜种子制剂中富含萝卜素的方法
    • US07371419B1
    • 2008-05-13
    • US11617934
    • 2006-12-29
    • Leslie G. WestNam-Cheol KimGeorge W. HaasNathan V. Matusheski
    • Leslie G. WestNam-Cheol KimGeorge W. HaasNathan V. Matusheski
    • A61K36/00
    • A61K36/31
    • The present invention relates to chemoprotective compounds and a method for producing chemoprotectant precursor-enriched extracts from crucifer seeds. More particularly, a method is provided for producing chemoprotectant precursor-enriched extracts from radish seeds with increased ratio of glucoraphanin to glucoraphenin. The general method comprises preparing an aqueous extract, contacting the aqueous extract with an adsorbent, removing the adsorbent to obtain a glucosinolate-containing extract, drying the glucosinolate-containing extract to obtain a dried glucosinolate-containing extract, mixing at least a portion of the dried glucosinolate-containing extract with a solvent to form a glucosinolate-containing suspension, clarifying the glucosinolate-containing suspension, contacting the glucosinolate-containing suspension with a catalyst, and introducing hydrogen for a time sufficient to obtain a chemoprotectant precursor-enriched extract. The chemoprotectant precursor-enriched extracts may be further processed to form a chemoprotectant precursor-enriched isolate or processed for use in various applications, including incorporation into a variety of food products and pharmaceuticals.
    • 本发明涉及化学保护性化合物和从十字花科植物种子生产富含化学保护素前体的提取物的方法。 更具体地,提供了一种用于从萝卜种子生产富含富含化学保护素前体的提取物的方法,其中葡萄糖苷与葡糖蓝精蛋白的比例增加。 一般方法包括制备水提取物,使含水提取物与吸附剂接触,除去吸附剂以获得含有硫代葡萄糖苷的提取物,干燥含有硫代葡萄糖苷的提取物以获得含有硫代葡萄糖苷的干燥提取物,将至少一部分 干燥的含有硫代葡萄糖苷的提取物与溶剂形成含有硫代葡萄糖苷的悬浮液,澄清含有硫代葡萄糖苷的悬浮液,使含有硫代葡萄糖苷的悬浮液与催化剂接触,并引入氢气足以获得富含化学保护剂前体的提取物。 可以进一步处理富含化学保护剂前体的提取物,以形成富含化学保护剂前体的分离物,或加工用于各种应用,包括掺入各种食品和药物中。