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1. 发明申请

US20060074413A1 Method and apparatus for substantial and uniform ablation about a linear bipolar array of electrodes 审中-公开
标题翻译：关于电极的线性双极阵列的实质上和均匀消融的方法和装置
公开(公告)号：US20060074413A1
公开(公告)日：2006-04-06
申请号：US11286832
申请日：2005-11-23
申请人： Kamran Behzadian
发明人： Kamran Behzadian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/148 , A61B2018/1467
摘要： The described invention relates to a medical device for substantially sized uniform ablation of animal or human tissue comprising of a bipolar generator for generating radio frequency at an electrode, a polarity alternator, a probe having a handle, and an elongated member, and a tip at the far end of the distal end suitable for insertion into tissue. The elongated member has a proximal and distal end with an electrode cluster of three or more electrodes located on the distal end of the elongated member. The electrodes are electrically insulated from each other and at least two of the electrodes have dissimilar polarity from each other wherein at least one of the electrodes has a high voltage polarity and at least one of the electrodes has a return polarity. During ablation, the polarity alternator changes the polarity of the electrodes to cycle lesion formation along the length of the electrode cluster repeatedly from electrode to electrode to form a spherical or near spherical lesion at the distal tip equal in diameter to the length of the cluster.
摘要翻译：所描述的本发明涉及一种用于动物或人体组织的基本尺寸均匀消融的医疗装置，包括用于在电极处产生射频的双极发生器，极性交流发电机，具有手柄的探头和细长构件，以及尖端远端的远端适于插入组织。细长构件具有近端和远端，其具有位于细长构件的远端上的三个或更多个电极的电极簇。电极彼此电绝缘，并且至少两个电极彼此具有不同的极性，其中至少一个电极具有高电压极性，并且至少一个电极具有返回极性。在消融期间，极性交流发电机改变电极的极性，沿着电极簇的长度重复地从电极到电极循环损伤形成，以在直径相等于簇的长度的远端处形成球形或近球形损伤。

2. 发明申请

US20150251004A1 SUTURELESS LEAD RETENTION FEATURES 审中-公开
标题翻译：无懈可击的铅保持功能
公开(公告)号：US20150251004A1
公开(公告)日：2015-09-10
申请号：US14719076
申请日：2015-05-21
申请人： Mir A. IMRAN , Albert G. BURDULIS , Kamran BEHZADIAN , Fred I. LINKER , Nicholas C. DEBEER , Arturo ROSQUETA
发明人： Mir A. IMRAN , Albert G. BURDULIS , Kamran BEHZADIAN , Fred I. LINKER , Nicholas C. DEBEER , Arturo ROSQUETA
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/057 , A61N2001/0585
摘要： A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. Alternatively, a system includes a lead, a lead body, at least one electrode; with a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.
摘要翻译：一种系统包括具有引线体和至少一个电极的引线; 以及保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置为当所述引线位于所述主体中时辅助将所述引线无损伤地固定到附近的组织。或者，系统包括引线，引线体，至少一个电极; 具有螺旋保持特征，沿着所述引线主体设置在所述至少一个电极附近并且被配置成有助于将所述引线附着到附近的组织。用于刺激靶神经组织的引线包括细长体; 沿着所述细长体设置的至少一个电极; 以及被动保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并被配置为有助于将所述细长主体锚定到所述靶神经组织附近的组织。

3. 发明申请

US20070016273A1 ELECTROTHERMAL INTERVERTEBRAL DISC TREATMENT 审中-公开
标题翻译：电热椎间盘治疗
公开(公告)号：US20070016273A1
公开(公告)日：2007-01-18
申请号：US11420673
申请日：2006-05-26
申请人： Nelson Scarborough , Kamran Behzadian , Ralph McNall
发明人： Nelson Scarborough , Kamran Behzadian , Ralph McNall
IPC分类号： A61F7/00 , A61F7/12
CPC分类号： A61B18/148 , A61B2018/00267 , A61B2018/0044 , A61B2018/1407 , A61B2018/143 , A61B2018/1435 , A61B2018/1467 , A61B2018/1475 , A61B2218/002
摘要： A method of treating an intervertebral disc includes actively steering a heat-delivery device in two dimensions to a region of a treatment site within the intervertebral disc, and heating the region of the treatment site. A heating element of the heat-delivery device includes various configurations to provide a large heating profile in order to heat, and cause denervation at, substantially all of the region of the treatment site.
摘要翻译：治疗椎间盘的方法包括主动地将二次传热装置转向椎间盘内的治疗部位的区域，以及加热治疗部位的区域。发热装置的加热元件包括各种构造，以提供大的加热曲线，以便在基本上所有处理部位的所有区域加热并导致去神经支配。

4. 发明申请

US20090125011A1 Devices, Methods and Kits for Substantial and Uniform Ablation about a Linear Bipolar Array of Electrodes 审中-公开
标题翻译：关于线性双极性电极阵列的大量和均匀消融的装置，方法和试剂盒
公开(公告)号：US20090125011A1
公开(公告)日：2009-05-14
申请号：US12269644
申请日：2008-11-12
申请人： KAMRAN BEHZADIAN
发明人： KAMRAN BEHZADIAN
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B18/1206 , A61B18/148 , A61B2018/124 , A61B2018/1467
摘要： The present invention relates to a medical device for substantially sized and uniform ablation of animal or human tissue comprising a bipolar generator for generating radio frequency at an electrode, a polarity alternator, an applicator probe having a handle and an elongated member, and a tip at the far end of the distal end suitable for insertion into tissue. The elongated member has a proximal and distal end with an electrode cluster of three or more electrodes located on the distal end of the elongated member. The electrodes are electrically insulated from each other and at least two of the electrodes have dissimilar polarity from each other wherein at least one of the electrodes has a high voltage polarity and at least one of the electrodes has a return polarity. During ablation, the polarity alternator automatically and repeatedly changes the polarity of the electrodes to cycle lesion formation along the length of the electrode cluster and alternate lesion formation repeatedly from one polarity to other polarity to form a spherical or near spherical lesion at the distal tip equal in diameter to the length of the cluster.
摘要翻译：本发明涉及一种用于动物或人体组织的基本尺寸和均匀消融的医疗装置，包括用于在电极处产生射频的双极发生器，极性交流发电机，具有手柄和细长构件的施用器探针，以及尖端远端的远端适于插入组织。细长构件具有近端和远端，其具有位于细长构件的远端上的三个或更多个电极的电极簇。电极彼此电绝缘，并且至少两个电极彼此具有不同的极性，其中至少一个电极具有高电压极性，并且至少一个电极具有返回极性。在消融期间，极性交流发电机自动并重复地改变电极的极性，沿着电极簇的长度循环损伤形成，并且从一个极性到另一个极性重复交替的病变形成，以在远端处形成球形或近球形损伤等于直径与簇的长度。

5. 发明授权

US06550472B2 Devices and methods for nebulizing fluids using flow directors 有权
公开(公告)号：US06550472B2
公开(公告)日：2003-04-22
申请号：US09809783
申请日：2001-03-16
申请人： Craig Litherland , Kamran Behzadian
发明人： Craig Litherland , Kamran Behzadian
IPC分类号： A61M1100
CPC分类号： A61M15/0085 , A61M11/005 , A61M15/0003 , B05B7/0408 , B05B17/0646
摘要： A device for nebulizing a fluid is supplied which has a flow director. The flow director helps to direct any bubbles formed by the nebulizing device away from the nebulizing device. The nebulizing device has a vibrating element with apertures through which the fluid is dispensed. A dispensing chamber is defined between the flow director and the vibrating element. The dispensing chamber has an inlet which is positioned below an outlet so that bubbles naturally migrate up and away from the vibrating element.

6. 发明申请

US20080183257A1 SUTURELESS LEAD RETENTION FEATURES 有权
标题翻译：无懈可击的铅保持功能
公开(公告)号：US20080183257A1
公开(公告)日：2008-07-31
申请号：US12022135
申请日：2008-01-29
申请人： Mir A. Imran , Albert G. Burdulis , Kamran Behzadian , Fred I. Linker , Nicholas C. Debeer , Arturo Rosqueta
发明人： Mir A. Imran , Albert G. Burdulis , Kamran Behzadian , Fred I. Linker , Nicholas C. Debeer , Arturo Rosqueta
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/057 , A61N2001/0585
摘要： A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. A system includes a lead having a lead body and at least one electrode; and a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue when the lead is positioned in a body. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.
摘要翻译：一种系统包括具有引线体和至少一个电极的引线; 以及保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置为当所述引线位于所述主体中时辅助将所述引线无损伤地固定到附近的组织。一种系统包括具有引线体和至少一个电极的引线; 以及螺旋保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置为当所述引线位于身体中时辅助将引线固定到附近的组织。用于刺激靶神经组织的引线包括细长体; 沿着所述细长体设置的至少一个电极; 以及被动保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置成有助于将所述细长体锚固到所述靶神经组织附近的组织。

7. 发明授权

US06546927B2 Methods and apparatus for controlling piezoelectric vibration 有权
公开(公告)号：US06546927B2
公开(公告)日：2003-04-15
申请号：US09805498
申请日：2001-03-13
申请人： Craig Litherland , Rob Burnside , Kamran Behzadian , Michael Klimowicz
发明人： Craig Litherland , Rob Burnside , Kamran Behzadian , Michael Klimowicz
IPC分类号： A61M1100
CPC分类号： B05B17/0646 , A61M11/005 , A61M15/0085 , B05B12/081 , B05B15/14 , B05B17/0669 , H01L41/042
摘要： A method for aerosolizing a liquid comprises providing an aerosol generator having a plate with a plurality of apertures and a piezoelectric element to vibrate the plate. Liquid is supplied to the plate, and the piezoelectric element is energized to vibrate the plate at an initial frequency. The energy level is adjusted to vibrate the plate at its instantaneous resonant frequency during aerosolization of the liquid.

8. 发明授权

US09044592B2 Sutureless lead retention features 有权
标题翻译：无缝导线保留功能
公开(公告)号：US09044592B2
公开(公告)日：2015-06-02
申请号：US12022135
申请日：2008-01-29
申请人： Mir A. Imran , Albert G. Burdulis , Kamran Behzadian , Fred I. Linker , Nicholas C. Debeer , Arturo Rosqueta
发明人： Mir A. Imran , Albert G. Burdulis , Kamran Behzadian , Fred I. Linker , Nicholas C. Debeer , Arturo Rosqueta
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/057 , A61N2001/0585
摘要： A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. A system includes a lead having a lead body and at least one electrode; and a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue when the lead is positioned in a body. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.
摘要翻译：一种系统包括具有引线体和至少一个电极的引线; 以及保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置为当所述引线位于所述主体中时辅助将所述引线无损伤地固定到附近的组织。一种系统包括具有引线体和至少一个电极的引线; 以及螺旋保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置为当所述引线位于身体中时辅助将引线固定到附近的组织。用于刺激靶神经组织的引线包括细长体; 沿着所述细长体设置的至少一个电极; 以及被动保持特征，沿着所述引线体设置在所述至少一个电极的近侧，并且被配置成有助于将所述细长体锚固到所述靶神经组织附近的组织。

9. 发明申请

US20110184325A1 ORTHOPEDIC APPARATUSES FOR MOBILIZING, STRETCHING AND PROTECTING THE SPINAL COLUMN 审中-公开
标题翻译：用于移动，拉伸和保护脊柱的矫形装置
公开(公告)号：US20110184325A1
公开(公告)日：2011-07-28
申请号：US13011913
申请日：2011-01-23
申请人： Kamran Behzadian , Lorne Eltherington , Farida Behzadian
发明人： Kamran Behzadian , Lorne Eltherington , Farida Behzadian
IPC分类号： A61F5/00
CPC分类号： A61F5/055 , A61F5/026
摘要： The described invention relates to devices for relief of spine pain and correcting posture. The device is a wearable frame equipped with a series of leaf or coil springs where the spring forces are adjusted so that the forces are applied parallel to the spine and are equal to or greater than the individual's body weight above the device. The compressed springs apply enough opposing force to transfer the downward force resulting from the weight to the body above the device to anatomy below the device while allowing normal spine motion relative to the body.
摘要翻译：本发明涉及用于缓解脊柱疼痛和矫正姿势的装置。该装置是装备有一系列叶片或螺旋弹簧的可穿戴框架，其中弹簧力被调节，使得力平行于脊柱施加并且等于或大于装置上方的个体体重。压缩弹簧施加足够的相反的力以将由重量产生的向下的力传递到装置上方的身体，使得身体下方的解剖结构同时允许相对于身体的正常的脊柱运动。

10. 发明申请

US20050288663A1 Method and apparatus for substantial uniform ablation about a bipolar array of electrodes 审中-公开
标题翻译：关于电极双极阵列的大量均匀消融的方法和装置
公开(公告)号：US20050288663A1
公开(公告)日：2005-12-29
申请号：US10878168
申请日：2004-06-28
申请人： Kamran Behzadian
发明人： Kamran Behzadian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/148 , A61B2018/1467
摘要： The described invention relates to a medical device for a substantially uniform ablation of animal or human tissue comprising of a bipolar generator for generating radio frequency at an electrode, a probe having a handle, and an elongated member. The elongated member has a proximal and distal end with an electrode cluster of three or more electrodes located on the distal end of the elongated member. The electrodes are electrically insulated from each other and at least two of the electrodes have dissimilar polarity from each other wherein at least one of the electrodes has a high voltage polarity and at least one of the electrodes has a return polarity. Also, during ablation, there is a polarity alternator for changing the polarity of the electrodes and a tip at the far end of the distal end suitable for insertion into tissue.
摘要翻译：所描述的本发明涉及一种用于动物或人体组织的基本上均匀消融的医疗装置，包括用于在电极处产生射频的双极发生器，具有手柄的探针和细长构件。细长构件具有近端和远端，其具有位于细长构件的远端上的三个或更多个电极的电极簇。电极彼此电绝缘，并且至少两个电极彼此具有不同的极性，其中至少一个电极具有高电压极性，并且至少一个电极具有返回极性。此外，在消融期间，存在用于改变电极的极性的极性交流发电机和适于插入组织的远端的远端的尖端。

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