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1. 发明授权

US06447920B1 Organic articles 有权
标题翻译：有机物品
公开(公告)号：US06447920B1
公开(公告)日：2002-09-10
申请号：US09697860
申请日：2000-10-27
申请人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
发明人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
IPC分类号： G02C704
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及新型复合材料，其包含（a）与其表面引发剂部分共价结合的无机或有机本体材料用于自由基聚合; 和（b）亲水性表面涂层，其可通过将权利要求中所述的一种或多种式（1）的不饱和烯键式不饱和亲水性大分子单体应用于提供有引发剂基团的本体材料表面并聚合所述大分子单体而获得。本发明的复合材料具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的期望特性，因此可用于制造生物医学制品如眼科装置。

2. 发明授权

US06734321B2 Organic articles 有权
标题翻译：有机物品
公开(公告)号：US06734321B2
公开(公告)日：2004-05-11
申请号：US10175656
申请日：2002-06-20
申请人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
发明人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
IPC分类号： C07C27520
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及新型复合材料，其包含（a）与其表面引发剂部分共价结合的无机或有机本体材料用于自由基聚合; 和（b）亲水性表面涂层，其可通过将权利要求中所述的一种或多种式（1）的不饱和烯键式不饱和亲水性大分子单体应用于提供有引发剂基团的本体材料表面并聚合所述大分子单体而获得。本发明的复合材料具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的期望特性，因此可用于制造生物医学制品如眼科装置。

3. 发明授权

US06271332B1 Polyurethanes made from polysiloxane/polyol macromers 有权
标题翻译：由聚硅氧烷/多元醇大分子单体制成的聚氨酯
公开(公告)号：US06271332B1
公开(公告)日：2001-08-07
申请号：US09091394
申请日：1999-04-20
申请人： Dieter Lohmann , Jens Höpken , Angelika Domschke
发明人： Dieter Lohmann , Jens Höpken , Angelika Domschke
IPC分类号： C08G7726
CPC分类号： C08G18/61 , G02B1/043 , Y10T428/31663 , C08L75/04
摘要： The present invention describes a polymer and a precursor thereof; a prepolymer made essentially from a macromer that is cross-linked, for example, via its free hydroxy groups with a polyisocyanate, the macromer being made essentially from a polysiloxane and a polyol component; processes for the production of such prepolymers and polymers; the use of such polymers, for example, as artificial corneas, as molded articles, especially as contact lens material; also the use of a prepolymer or polymer for coating surfaces, especially functionalized polymer surfaces.
摘要翻译：本发明描述了聚合物及其前体; 基本上由大分子单体制备的预聚物，其例如通过其游离羟基与多异氰酸酯交联，大分子单体主要由聚硅氧烷和多元醇组分制成; 制备这种预聚物和聚合物的方法; 使用这样的聚合物，例如作为人造角膜，作为模制品，特别是作为隐形眼镜材料; 还使用预聚物或聚合物来涂覆表面，特别是官能化的聚合物表面。

4. 发明授权

US06951894B1 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US06951894B1
公开(公告)日：2005-10-04
申请号：US09640526
申请日：2000-08-17
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
IPC分类号： G02C7/04 , A61F20060101 , A61F2/14 , A61L27/00 , A61L27/26 , A61L27/34 , B05D7/24 , B29C39/42 , B29C71/00 , B29D11/00 , C08F220/22 , C08F290/06 , C08F290/14 , C08F299/08 , C08G20060101 , C08G18/10 , C08G18/48 , C08G18/50 , C08G18/61 , C08G18/67 , C08G18/81 , C08G18/83 , C08G77/00 , C08G77/04 , C08G77/46 , C08J5/00 , C08K3/00 , C08L20060101 , C08L33/08 , C08L33/10 , C08L83/04 , G02B1/04 , G02C20060101
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有很大的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含氧大分子单体和离子单体单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

5. 发明授权

US06734281B2 Organic polymers 有权
标题翻译：有机聚合物
公开(公告)号：US06734281B2
公开(公告)日：2004-05-11
申请号：US10106717
申请日：2002-03-26
申请人： Jens Höpken , Dieter Lohmann
发明人： Jens Höpken , Dieter Lohmann
IPC分类号： C08G7500
CPC分类号： G02B1/043 , C08F290/04 , C08G81/024 , C08L83/10 , C08L71/00
摘要： The invention relates to novel oligomers of formula wherein the variables are as defined in the claims. The oligomers of the invention are especially useful for the manufacture of biomedical moldings, for example ophthalmic moldings such as in particular contact lenses.
摘要翻译：本发明涉及式的新型低聚物，其变量如权利要求中所定义。本发明的低聚物特别可用于制造生物医学模制品，例如眼用模制品，例如特别是隐形眼镜。

6. 发明授权

US06715874B1 Organic polymers 失效
标题翻译：有机聚合物
公开(公告)号：US06715874B1
公开(公告)日：2004-04-06
申请号：US09627807
申请日：2000-07-28
申请人： Jens Höpken , Dieter Lohmann
发明人： Jens Höpken , Dieter Lohmann
IPC分类号： G02C702
CPC分类号： G02B1/043 , C08F290/04 , C08G81/024 , C08L83/10 , C08L71/00
摘要： The invention relates to novel crosslinkable copolymers of formula wherein the variables are as defined in the claims. The copolymers of the invention are especially useful for the manufacture of biomedical moldings, for example ophthalmic moldings such as in particular contact lenses.
摘要翻译：本发明涉及式（1）的新型可交联共聚物，其变量如权利要求中所定义。本发明的共聚物特别可用于制造生物医学模制品，例如眼用模制品，例如隐形眼镜。

7. 发明授权

US06169127A Plasma-induced polymer coatings 失效
标题翻译：等离子体诱导的聚合物涂层
公开(公告)号：US06169127A
公开(公告)日：2001-01-02
申请号：US09077505
申请日：1998-06-02
申请人： Dieter Lohmann , Peter Chabrecek , Jens Höpken
发明人： Dieter Lohmann , Peter Chabrecek , Jens Höpken
IPC分类号： G02C704
CPC分类号： B05D1/62 , A61L27/34 , C08L33/00 , C08L39/06
摘要： The present invention relates to coated particles wherein the polymer chains of the coating are obtainable by after-glow plasma induced polymerization of a monomer under special plasma conditions. The invention further relates to a method for the production of articles coated with a polymer having these features.
摘要翻译：本发明涉及涂覆的颗粒，其中涂层的聚合物链可通过在特殊等离子体条件下单体的后辉度等离子体诱导聚合而获得。本发明还涉及一种制备涂覆有具有这些特征的聚合物的制品的方法。

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