专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06951894B1 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US06951894B1
公开(公告)日：2005-10-04
申请号：US09640526
申请日：2000-08-17
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
IPC分类号： G02C7/04 , A61F20060101 , A61F2/14 , A61L27/00 , A61L27/26 , A61L27/34 , B05D7/24 , B29C39/42 , B29C71/00 , B29D11/00 , C08F220/22 , C08F290/06 , C08F290/14 , C08F299/08 , C08G20060101 , C08G18/10 , C08G18/48 , C08G18/50 , C08G18/61 , C08G18/67 , C08G18/81 , C08G18/83 , C08G77/00 , C08G77/04 , C08G77/46 , C08J5/00 , C08K3/00 , C08L20060101 , C08L33/08 , C08L33/10 , C08L83/04 , G02B1/04 , G02C20060101
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有很大的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含氧大分子单体和离子单体单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

2. 发明授权

US06169127A Plasma-induced polymer coatings 失效
标题翻译：等离子体诱导的聚合物涂层
公开(公告)号：US06169127A
公开(公告)日：2001-01-02
申请号：US09077505
申请日：1998-06-02
申请人： Dieter Lohmann , Peter Chabrecek , Jens Höpken
发明人： Dieter Lohmann , Peter Chabrecek , Jens Höpken
IPC分类号： G02C704
CPC分类号： B05D1/62 , A61L27/34 , C08L33/00 , C08L39/06
摘要： The present invention relates to coated particles wherein the polymer chains of the coating are obtainable by after-glow plasma induced polymerization of a monomer under special plasma conditions. The invention further relates to a method for the production of articles coated with a polymer having these features.
摘要翻译：本发明涉及涂覆的颗粒，其中涂层的聚合物链可通过在特殊等离子体条件下单体的后辉度等离子体诱导聚合而获得。本发明还涉及一种制备涂覆有具有这些特征的聚合物的制品的方法。

3. 发明授权

US06447920B1 Organic articles 有权
标题翻译：有机物品
公开(公告)号：US06447920B1
公开(公告)日：2002-09-10
申请号：US09697860
申请日：2000-10-27
申请人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
发明人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
IPC分类号： G02C704
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及新型复合材料，其包含（a）与其表面引发剂部分共价结合的无机或有机本体材料用于自由基聚合; 和（b）亲水性表面涂层，其可通过将权利要求中所述的一种或多种式（1）的不饱和烯键式不饱和亲水性大分子单体应用于提供有引发剂基团的本体材料表面并聚合所述大分子单体而获得。本发明的复合材料具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的期望特性，因此可用于制造生物医学制品如眼科装置。

4. 发明授权

US06734321B2 Organic articles 有权
标题翻译：有机物品
公开(公告)号：US06734321B2
公开(公告)日：2004-05-11
申请号：US10175656
申请日：2002-06-20
申请人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
发明人： Peter Chabrecek , Jens Höpken , Dieter Lohmann
IPC分类号： C07C27520
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及新型复合材料，其包含（a）与其表面引发剂部分共价结合的无机或有机本体材料用于自由基聚合; 和（b）亲水性表面涂层，其可通过将权利要求中所述的一种或多种式（1）的不饱和烯键式不饱和亲水性大分子单体应用于提供有引发剂基团的本体材料表面并聚合所述大分子单体而获得。本发明的复合材料具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的期望特性，因此可用于制造生物医学制品如眼科装置。

5. 发明授权

US07538146B2 Extended wear ophthalmic lens 失效
公开(公告)号：US07538146B2
公开(公告)日：2009-05-26
申请号：US11618800
申请日：2006-12-30
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： C08F290/06
CPC分类号： G02B1/043 , A61L27/26 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , C08L43/04 , C08L75/04 , C08L51/085 , C08L2666/20 , C08L51/08 , C08L83/04 , C08L33/00 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

6. 发明授权

US07468398B2 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US07468398B2
公开(公告)日：2008-12-23
申请号：US11146586
申请日：2005-06-07
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： C08F290/06
CPC分类号： G02B1/043 , A61L27/26 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , C08L43/04 , C08L75/04 , C08L51/085 , C08L2666/20 , C08L51/08 , C08L83/04 , C08L33/00 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有实质的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含氧大分子单体和离子单体单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

7. 发明授权

US06730366B2 Process for modifying a surface 有权
标题翻译：改变表面的工艺
公开(公告)号：US06730366B2
公开(公告)日：2004-05-04
申请号：US10056168
申请日：2002-01-24
申请人： Dieter Lohmann , Peter Chabrecek , Jörg Leukel
发明人： Dieter Lohmann , Peter Chabrecek , Jörg Leukel
IPC分类号： C23C1428
CPC分类号： C08J7/047 , Y10T428/31504 , Y10T428/31623
摘要： The invention relates to a process for coating a material surface comprising the steps of: (a) applying to the material surface one or more different comb-type polymers comprising a polymer backbone and side chains pendently attached thereto, wherein at least a part of the side chains carry a triggerable precursor for carbene or nitrene formation; and (b) fixing the polymer(s) onto the material surface using heat or radiation, in particular radiation such as UV or visible light. The polymers of the invention are useful for the modification of material surfaces and are particularly suitable for providing biomedical articles such as contact lenses with a hydrophilic coating.
摘要翻译：本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）向材料表面施加一种或多种不同的梳型聚合物，其包含聚合物主链和侧链附着于其上，其中至少一部分侧链携带可触发的卡宾或者氮烯形成前体; 和（b）使用热或辐射，特别是诸如UV或可见光的辐射将聚合物固定在材料表面上。本发明的聚合物可用于改性材料表面，并且特别适用于提供生物医学制品例如具有亲水涂层的隐形眼镜。

8. 发明授权

US5939466A Poly-unsaturated carbohydrate derivatives, polymers thereof and their use 失效
标题翻译：多不饱和碳水化合物衍生物及其用途及其用途
公开(公告)号：US5939466A
公开(公告)日：1999-08-17
申请号：US817044
申请日：1997-04-04
申请人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
发明人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
IPC分类号： G02C7/04 , A61K9/00 , A61K47/36 , C07D493/04 , C07H13/12 , C07H15/04 , C08B37/00 , C08B37/16 , C08F12/00 , C08F18/00 , C08F20/36 , C08F220/36 , G02B1/04 , G02B1/10 , C07H15/02 , C07H265/04
CPC分类号： C07D493/04 , C07H13/12 , C07H15/04 , C08B37/0012 , C08F220/36 , G02B1/043
摘要： The present invention relates to polymerizable derivatives of carbohydrates comprising a carbohydrate radical and more than one radically polymerizable hydrocarbon group which is linked optionally via a spacer to the carbohydrate radical, to homopolymers, copolymers, block copolymers, graft copolymers and polymeric networks thereof, to capsules, fibers, films and coatings having water-binding and biocompatible properties, and to molded articles, for example contact lenses or biomedicinal articles, comprising the mentioned polymers, as well as to processes for the preparation of the mentioned polymers and articles.
摘要翻译： PCT No.PCT / EP95 / 04052 Sec。 371日期1997年04月4日 102（e）日期1997年4月4日PCT提交1995年10月16日PCT公布。第WO96 / 13511号公报日期1996年5月9日本发明涉及碳水化合物的可聚合衍生物，其包含碳水化合物基团和多于一个可自由基聚合的烃基，其任选经由间隔基连接至碳水化合物基团，至均聚物，共聚物，嵌段共聚物，接枝共聚物和聚合物网络具有水结合和生物相容性质的胶囊，纤维，膜和涂层，以及包含所述聚合物的模制品，例如隐形眼镜或生物医学制品，以及制备所述聚合物和制品的方法。

9. 发明授权

US5612391A Functionalized photoinitiators, macromers thereof, and the use thereof for contact lens 失效
标题翻译：官能化光引发剂，其大分子单体及其用于隐形眼镜的用途
公开(公告)号：US5612391A
公开(公告)日：1997-03-18
申请号：US469399
申请日：1995-06-06
申请人： Peter Chabrecek , Dieter Lohmann
发明人： Peter Chabrecek , Dieter Lohmann
IPC分类号： G02C7/04 , C07C49/76 , C07C49/82 , C07C271/20 , C07C271/24 , C07C271/28 , C07C271/32 , C07C271/38 , C07D317/26 , C07F7/10 , C08B31/00 , C08B33/00 , C08B37/00 , C08B37/08 , C08B37/16 , C08F2/48 , C08F2/50 , C08F8/30 , C08F16/36 , C08G18/00 , C08G18/08 , C08G18/71 , C08G77/04 , C08G77/38 , C08J3/28 , C08J7/12 , C08J7/18 , C08L101/02 , G02B1/04 , G03F7/031 , G03F7/075 , C08J5/00 , C08J5/18 , C08J7/04
CPC分类号： G03F7/075 , C07C271/20 , C07C271/24 , C07C271/28 , C07C271/38 , C08B37/0012 , C08B37/0072 , C08F2/50 , C08F8/30 , C08G77/38 , C08J7/12 , C08J7/18 , G02B1/043 , G03F7/031 , C07C2101/14 , Y10S522/904 , Y10S522/905 , Y10T428/31645 , Y10T428/31663 , Y10T428/31667 , Y10T428/31855 , Y10T428/31971
摘要： Contact lenses formed from compounds of formula I: ##STR1## are disclosed. The compounds are photoinitiators which can be functionalized by means of ethylenic groups or can be bonded to H-active substances, in order, for example, to modify surfaces by means of photopolymerizable substances. The compounds are especially useful in the manufacture of contact lenses.
摘要翻译：公开了由式I化合物形成的隐形眼镜：。这些化合物是可以通过烯属基官能化或可以与H-活性物质结合的光引发剂，以便例如通过可光聚合物质来修饰表面。这些化合物在隐形眼镜的制造中特别有用。

10. 发明授权

US08568626B2 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US08568626B2
公开(公告)日：2013-10-29
申请号：US12252406
申请日：2008-10-16
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： B29D11/00
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionoperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.
摘要翻译：提供了制备硅酮水凝胶隐形眼镜的方法。在一个实施方案中，预聚物混合物在具有小于约10000ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于连续磨损一段时间后产生小于10％的角膜溶胀包括正常睡眠期为7天。在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或至少一种离子交换材料和交联剂。在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式