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1. 发明授权

US08932340B2 Bifurcated stent and delivery system 有权
标题翻译：分叉支架和分娩系统
公开(公告)号：US08932340B2
公开(公告)日：2015-01-13
申请号：US12129372
申请日：2008-05-29
申请人： Michael P. Meyer , Michael W. Davis , Benjamin Arcand , Jay Rassat , James Anderson , Derek Sutermeister
发明人： Michael P. Meyer , Michael W. Davis , Benjamin Arcand , Jay Rassat , James Anderson , Derek Sutermeister
IPC分类号： A61F2/06 , A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61M25/10
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61M2025/1013
摘要： A delivery system has a stent and a balloon. The stent has a first section made of a plurality of interconnected framework members which define a plurality of potential side branches. The balloon is a dual lumen balloon that can inflate from the proximal end to the distal end with a plurality of protrusions and/or herniations.
摘要翻译：输送系统具有支架和气囊。支架具有由多个互连的框架构件制成的第一部分，其限定多个潜在的侧分支。气囊是可以从多个突起和/或疝的近端膨胀到远端的双腔气囊。

2. 发明授权

US07998164B2 Intravascular filter with centering member 失效
标题翻译：带定心构件的血管内滤器
公开(公告)号：US07998164B2
公开(公告)日：2011-08-16
申请号：US11077584
申请日：2005-03-11
申请人： Douglas R. Saholt , Jay Rassat , Mel R. Beulke , Steven E. Peterson
发明人： Douglas R. Saholt , Jay Rassat , Mel R. Beulke , Steven E. Peterson
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61M25/04
摘要： Devices and methods for centering an intravascular filter within a blood vessel are disclosed. A filter system in accordance with an exemplary embodiment of the present invention may include an intravascular filter, a filter sheath adapted to contain the intravascular filter, and a centering member adapted to assume a preset shape when deployed within a blood vessel. The centering member may comprise an elongated wire having a hoop section adapted to radially expand against the inner wall of the blood vessel when deployed. In some embodiments, multiple centering members can be employed to facilitate centering of both the intravascular filter and the filter sheath within the blood vessel, if desired.
摘要翻译：公开了一种用于使血管内过滤器在血管内居中的装置和方法。根据本发明的示例性实施例的过滤器系统可以包括血管内过滤器，适于容纳血管内过滤器的过滤器护套，以及适于在部署在血管内时呈现预设形状的定心构件。定心构件可以包括细长的线，其具有适于在展开时径向膨胀抵靠血管的内壁的箍部分。在一些实施例中，如果需要，可以使用多个定心构件以促进血管内过滤器和过滤器护套在血管内的定心。

3. 发明申请

US20090036977A1 DRUG-RELEASING STENT HAVING EXTENSION(S) FOR TREATING LONG LESIONS 审中-公开
标题翻译：具有延长治疗长期作用的药物释放手段
公开(公告)号：US20090036977A1
公开(公告)日：2009-02-05
申请号：US12103750
申请日：2008-04-16
申请人： Jay Rassat , Derek Sutermeister , Scott Petersen
发明人： Jay Rassat , Derek Sutermeister , Scott Petersen
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2002/91525 , A61F2002/91541 , A61F2002/91575 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0039 , A61F2250/006 , A61F2250/0067
摘要： This invention generally relates to a system for treating body lumens, comprising stents, such as intravascular stents. More particularly, the invention is directed to stents having extensions attached on the ends thereof. The invention is also directed to methods for making and using such stents.
摘要翻译：本发明一般涉及用于治疗体腔的系统，包括支架，例如血管内支架。更具体地，本发明涉及在其端部上具有延伸部的支架。本发明还涉及制造和使用这种支架的方法。

4. 发明申请

US20090036830A1 Bifurcation Treatment System and Methods 有权
标题翻译：分岔治疗系统及方法
公开(公告)号：US20090036830A1
公开(公告)日：2009-02-05
申请号：US11832394
申请日：2007-08-01
申请人： Brian Jablonski , Jay Rassat
发明人： Brian Jablonski , Jay Rassat
IPC分类号： A61M25/04
CPC分类号： A61M25/1011 , A61F2/856 , A61F2/954 , A61F2/958 , A61M25/1002 , A61M2025/0058 , A61M2025/1045
摘要： A catheter assembly configured for treatment of a vessel bifurcation. The catheter assembly includes a catheter shaft and first and second balloons. The second balloon extends radially outward relative to the first balloon when expanded. A valve arrangement controls expansion of the second balloon. Portions of the valve arrangement can be positioned at proximal and distal end portions of the catheter shaft. Typically, the first balloon is expanded followed by expansion of the second balloon. A stent having a lateral branch opening is operatively mounted to the first balloon. The second balloon is configured to extend through the lateral branch opening when the second balloon is expanded.
摘要翻译：构造成用于治疗血管分叉的导管组件。导管组件包括导管轴和第一和第二气囊。当膨胀时，第二气囊相对于第一气囊径向向外延伸。阀装置控制第二气囊的膨胀。阀装置的部分可以定位在导管轴的近端部分和远端部分。通常，第一气囊膨胀，随后膨胀第二气囊。具有侧向分支开口的支架可操作地安装到第一气囊。第二气囊构造成当第二气囊膨胀时延伸通过侧向分支开口。

5. 发明授权

US08414632B2 Adjustable catheter tip 有权
标题翻译：可调式导管头
公开(公告)号：US08414632B2
公开(公告)日：2013-04-09
申请号：US11368927
申请日：2006-03-06
申请人： Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
发明人： Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61M25/001 , A61B2017/00398 , A61B2017/00871 , A61M25/0069 , A61M25/0074 , A61M25/10 , A61M2025/0024 , A61M2025/0058 , A61M2025/0063 , A61M2025/09125
摘要： A catheter tip has an outer surface section, an inner surface section, a spatial configuration and at least one segment of electroactive polymer. The inner surface section defines a guide wire lumen. The electroactive polymer has an actuated state and a non-actuated state. In an actuated state, the electroactive polymer alters the spatial configuration of the catheter tip.
摘要翻译：导管尖端具有外表面部分，内表面部分，空间构造和至少一个电活性聚合物部分。内表面部分限定导丝管腔。电活性聚合物具有致动状态和非致动状态。在致动状态下，电活性聚合物改变导管尖端的空间构型。

6. 发明授权

US07767726B2 Medical devices having crosslinked polymeric surfaces 有权
标题翻译：具有交联聚合物表面的医疗装置
公开(公告)号：US07767726B2
公开(公告)日：2010-08-03
申请号：US11801895
申请日：2007-05-11
申请人： Derek Sutermeister , Jay Rassat
发明人： Derek Sutermeister , Jay Rassat
IPC分类号： A61K6/083
CPC分类号： A61L31/048 , A61L31/10 , Y10T428/261 , Y10T428/2809 , C08L53/00
摘要： According to an aspect of the invention, medical devices are provided which contain at least one polymeric region. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer. Moreover, the polymeric region contains at least one surface sub-region that is crosslinked and at least one bulk sub-region that is substantially non-crosslinked. According to another aspect of the invention, a method is provided which includes exposing a polymeric region of a medical device to energetic species such that at least one surface sub-region of the polymeric region becomes crosslinked and at least one bulk sub-region remains substantially non-crosslinked. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer.
摘要翻译：根据本发明的一个方面，提供了包含至少一个聚合物区域的医疗装置。聚合物区域含有至少一种共聚物，其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。此外，聚合物区域包含至少一个交联的表面亚区域和基本上未交联的至少一个整体亚区域。根据本发明的另一方面，提供了一种方法，其包括将医疗装置的聚合物区域暴露于能量物质，使得聚合物区域的至少一个表面亚区域变得交联，并且至少一个体积亚区域基本上保持非交联的。聚合物区域含有至少一种共聚物，其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。

7. 发明申请

US20090177261A1 Detachment mechanisms for implantable devices 审中-公开
标题翻译：可植入装置的分离机构
公开(公告)号：US20090177261A1
公开(公告)日：2009-07-09
申请号：US12319255
申请日：2009-01-05
申请人： Clifford Teoh , Michael Williams , Gregory E. Mirigian , Kirsten Carroll , James M. Anderson , Jay Rassat , Benjamin Arcand , Derek Sutermeister
发明人： Clifford Teoh , Michael Williams , Gregory E. Mirigian , Kirsten Carroll , James M. Anderson , Jay Rassat , Benjamin Arcand , Derek Sutermeister
IPC分类号： A61M29/00 , A61F2/06 , A61B19/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209
摘要： Disclosed herein are detachment mechanisms for vaso-occlusive devices that allow for rapid operator-controlled release of the vaso-occlusive device into the selected site. Also disclosed are vaso-occlusive assemblies comprising these detachment mechanisms and methods of using these detachment mechanisms and vaso-occlusive assemblies.
摘要翻译：本文公开了一种用于血管闭塞装置的分离机构，其允许快速操作者控制将血管闭塞装置释放到选定部位。还公开了包括这些分离机构的血管闭塞组件和使用这些分离机构和血管闭塞组件的方法。

8. 发明申请

US20080279911A1 Medical devices having crosslinked polymeric surfaces 有权
标题翻译：具有交联聚合物表面的医疗装置
公开(公告)号：US20080279911A1
公开(公告)日：2008-11-13
申请号：US11801895
申请日：2007-05-11
申请人： Derek Sutermeister , Jay Rassat
发明人： Derek Sutermeister , Jay Rassat
IPC分类号： A61F2/02 , B32B17/10 , C08F112/02 , C08J3/28 , C08K5/15
CPC分类号： A61L31/048 , A61L31/10 , Y10T428/261 , Y10T428/2809 , C08L53/00
摘要： According to an aspect of the invention, medical devices are provided which contain at least one polymeric region. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer. Moreover, the polymeric region contains at least one surface sub-region that is crosslinked and at least one bulk sub-region that is substantially non-crosslinked. According to another aspect of the invention, a method is provided which includes exposing a polymeric region of a medical device to energetic species such that at least one surface sub-region of the polymeric region becomes crosslinked and at least one bulk sub-region remains substantially non-crosslinked. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer.
摘要翻译：根据本发明的一个方面，提供了包含至少一个聚合物区域的医疗装置。聚合物区域含有至少一种共聚物，其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。此外，聚合物区域包含至少一个交联的表面亚区域和基本上未交联的至少一个整体亚区域。根据本发明的另一方面，提供了一种方法，其包括将医疗装置的聚合物区域暴露于能量物质，使得聚合物区域的至少一个表面亚区域变得交联，并且至少一个体积亚区域基本上保持非交联的。聚合物区域含有至少一种共聚物，其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。

9. 发明申请

US20080125706A1 Electrically actuated annelid 有权
标题翻译：电动宣告
公开(公告)号：US20080125706A1
公开(公告)日：2008-05-29
申请号：US11506491
申请日：2006-08-18
申请人： Derek Sutermeister , Jay Rassat , Dan Wefel
发明人： Derek Sutermeister , Jay Rassat , Dan Wefel
IPC分类号： A61M25/082 , A61F2/00 , A61M25/092
CPC分类号： A61M25/0116 , A61M31/00 , A61M2025/0058
摘要： An apparatus for delivery through a vessel including an extensor segment and first and second anchor segments positioned on either side of the extensor segment, wherein each segment has associated with it an individually-addressable electro-active polymer.
摘要翻译：一种用于通过血管输送的装置，包括伸肌段和位于伸肌段两侧的第一和第二锚定段，其中每个区段与其相关联的是单独寻址的电活性聚合物。

10. 发明申请

US20080113083A1 Medical devices having adherent polymeric layers with depth-dependent properties 有权
标题翻译：具有与深度相关性质的贴壁聚合物层的医疗装置
公开(公告)号：US20080113083A1
公开(公告)日：2008-05-15
申请号：US11983952
申请日：2007-11-13
申请人： Derek Sutermeister , Jay Rassat , James Anderson
发明人： Derek Sutermeister , Jay Rassat , James Anderson
IPC分类号： A61L33/00 , A61F2/01 , A61F2/24 , A61N1/00 , A61F2/82
CPC分类号： A61L31/10 , A61L31/14 , Y10T428/31678
摘要： According to one aspect of the invention, a method of forming a medical device is provided, which includes: (a) contacting a substrate with a solution that contains (i) one or more types of polymers, (ii) a solvent that contains one or more types of solvent species, and (iii) one or more optional agents, for example, one or more therapeutic agents, among others; and (b) removing the solvent from the solution, thereby forming a polymeric layer on the substrate. The composition of the solution is changed over the course of forming the polymeric layer. In another aspect of the invention, a medical device is provided, which includes a substrate and a polymeric layer over the substrate. The polymeric layer contains a copolymer that contains differing first and second monomers. The lower surface of the polymeric layer contacting the substrate has a surface concentration of the first monomer relative to the second monomer that is higher than that of the upper surface of the polymeric layer opposite the substrate.
摘要翻译：根据本发明的一个方面，提供了一种形成医疗装置的方法，其包括：（a）使基底与包含（i）一种或多种聚合物的溶液接触，（ii）含有一种或更多类型的溶剂物质，和（iii）一种或多种任选的试剂，例如一种或多种治疗剂等; 和（b）从溶液中除去溶剂，由此在基材上形成聚合物层。在形成聚合物层的过程中改变溶液的组成。在本发明的另一方面，提供了一种医疗装置，其包括衬底和在衬底上的聚合物层。聚合物层含有含有不同的第一和第二单体的共聚物。接触基材的聚合物层的下表面具有相对于第二单体的第一单体的表面浓度高于与基材相对的聚合物层的上表面的表面浓度。

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