专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06784167B2 17-beta-hydroxysteroid dehydrogenase-II inhibitors 失效
标题翻译： 17-β-羟基类固醇脱氢酶II抑制剂
公开(公告)号：US06784167B2
公开(公告)日：2004-08-31
申请号：US09967430
申请日：2001-09-28
申请人： Jill E. Wood , Jeremy L. Baryza , Catherine R. Brennan , Soongyu Choi , James H. Cook , Brian R. Dixon , Paul P. Ehrlich , David E. Gunn , Ian McAlexander , Peiying Liu , Derek B. Lowe , Anikó M. Redman , William J. Scott , Yamin Wang
发明人： Jill E. Wood , Jeremy L. Baryza , Catherine R. Brennan , Soongyu Choi , James H. Cook , Brian R. Dixon , Paul P. Ehrlich , David E. Gunn , Ian McAlexander , Peiying Liu , Derek B. Lowe , Anikó M. Redman , William J. Scott , Yamin Wang
IPC分类号： A61K3140
CPC分类号： C07D207/26 , C07D207/325 , C07D403/06 , C07D405/06 , C07D409/04 , C07D409/06 , C07D417/06
摘要： 17-beta-hydroxysteroid dehydrogenase-II inhibitors having the structural formula wherein the phenyl group labeled A and the group —C(R4)(R6)Y are oriented cis to each other; W represents O or S; R1 represents —H or optionally substituted —(C1-C4)alkyl; n represents 0 or an integer of 1-3; and R2 represents any of a variety of substituents on ring A. R4 generally represents —H but may be a bond terminating at the ortho position of ring A. Y represents fluorine, —OR5, or —SR5, and R5 represents —H, optionally substituted —(C1-C4)alkyl, optionally substituted -phenyl, optionally substituted —(C1-C4)alkyl-phenyl, or optionally substituted —(C1-C4)acyl. R6 represents any of a variety of groups as defined in the specification and claims, including heteroaryl, arylalkyl, heteroarylalkyl, arylalkenyl, heteroarylalkenyl, alkynyl, arylalkynyl, heteroarylalkynyl, aryl, and indolyl. Pharmaceutically acceptable salts and N-oxides of these materials are also included. Also claimed are pharmaceutical compositions containing these materials and methods of using them.
摘要翻译：具有被标记为A的苯基的基团的结构式-17-β-羟基类固醇脱氢酶II抑制剂和基团-C（R 4）（R 6）Y取代为彼此顺式; W表示O或S; R 1表示-H或任选取代的 - （C 1 -C 4）烷基; n表示0或1-3的整数; 并且R 2代表环A上的任何取代基.R 4通常表示-H，但可以是在环A的邻位终止的键.Y表示氟，-OR 5或 - （C 1 -C 4）烷基，任选取代的 - 苯基，任选取代的（C 1 -C 4）烷基 - 苯基或任选取代的 - （C 1 -C 4）酰基。 R 6表示说明书和权利要求中定义的各种基团中的任何一种，包括杂芳基，芳基烷基，杂芳基烷基，芳基烯基，杂芳基烯基，炔基，芳基炔基，杂芳基炔基，芳基和吲哚基。也包括这些材料的药学上可接受的盐和N-氧化物。还要求保护的是含有这些材料的药物组合物和使用它们的方法。

2. 发明授权

US06657188B1 Method and apparatus for magnetically guiding neutral particles 失效
标题翻译：用于磁性引导中性粒子的方法和装置
公开(公告)号：US06657188B1
公开(公告)日：2003-12-02
申请号：US09640639
申请日：2000-08-17
申请人： Randall Gardner Hulet , Kevin Edwin Strecker , Jordan Mitchell Gerton , William Ian McAlexander , Curtis Charles Bradley , Jeffrey J Tollett , Charles Ackley Sackett , Bita Ghaffari , Stephen Calvin Moss
发明人： Randall Gardner Hulet , Kevin Edwin Strecker , Jordan Mitchell Gerton , William Ian McAlexander , Curtis Charles Bradley , Jeffrey J Tollett , Charles Ackley Sackett , Bita Ghaffari , Stephen Calvin Moss
IPC分类号： H05H302
CPC分类号： H05H3/04
摘要： Neutral particles, such as atoms and molecules, transported along a path having at least one curved region are selectively conveyed or filtered according to each particle's velocity by generating an inhomogeneous magnetic field across a cross-section of the path. The neutral particles may be transported through a physical tube or simply through the region defined by the magnetic field. The path may have more than one curved region and may additionally have one or more straight regions. The magnetic field may be generated for example by homogeneously or inhomogeneously magnetized permanent magnets or by current carrying elements. The magnetic elements may additionally be used in conjunction with at least one piece of a high permeability magnetic material for focussing or containing the magnetic field.
摘要翻译：沿着具有至少一个弯曲区域的路径传送的中性粒子（例如原子和分子）根据每个粒子的速度通过在路径的横截面上产生不均匀的磁场来选择性地传送或过滤。中性粒子可以通过物理管或简单地通过由磁场限定的区域传送。路径可以具有多于一个的弯曲区域，并且还可以具有一个或多个直的区域。磁场可以例如通过均匀或不均匀磁化的永磁体或通过载流元件产生。磁性元件可另外与至少一片高磁导率磁性材料结合使用，用于聚焦或包含磁场。

3. 发明授权

US07280770B2 Polarization diverse optical receiver using a polarization-dependent beam splitter 失效
标题翻译：使用偏振相关光束分离器的偏振多种光接收机
公开(公告)号：US07280770B2
公开(公告)日：2007-10-09
申请号：US10848229
申请日：2004-05-18
申请人： Tun S. Tan , Doug Baney , William Ian McAlexander , Richard P. Tella
发明人： Tun S. Tan , Doug Baney , William Ian McAlexander , Richard P. Tella
IPC分类号： H04B10/00
CPC分类号： H04B10/61 , H04B10/614 , H04B10/64
摘要： A receiver and method for using the same to process optical signals is disclosed. The receiver includes an optical coupler and a polarization dependent beam splitter. The optical coupler combines an input signal and a local oscillator signal into a first combined signal. The optical coupler includes a polarization filter that operates on the local oscillator to provide a linearly polarized signal having a predetermined LO polarization direction.
摘要翻译：公开了一种用于使用它来处理光信号的接收机和方法。接收机包括光耦合器和偏振相关光束分离器。光耦合器将输入信号和本地振荡器信号组合成第一组合信号。光耦合器包括对本地振荡器进行操作以提供具有预定的LO极化方向的线偏振信号的偏振滤波器。

4. 发明授权

US06724468B2 Single sweep phase shift method and apparatus for measuring chromatic and polarization dependent dispersion 失效
标题翻译：用于测量色散和偏振的色散的单次扫描相移方法和装置
公开(公告)号：US06724468B2
公开(公告)日：2004-04-20
申请号：US10211018
申请日：2002-07-31
申请人： William Ian McAlexander , Gregory Douglas VanWiggeren
发明人： William Ian McAlexander , Gregory Douglas VanWiggeren
IPC分类号： G01N2100
CPC分类号： G01M11/336 , G01M11/3181
摘要： A method for determining at least one optical property of an optical device comprises providing an optical input signal that includes first and second signal components that are modulated at first and second frequencies, respectively, and that have first and second polarization states, respectively. The optical input signal is passed to an optical device. An optical output signal from the optical device is separated into first and second output signals that have third and fourth polarization states, respectively. The first and second output signals are each compared with reference signals at the first and second frequencies to provide four phase shift and amplitude measurements that can be used to determine the at least one optical property of the optical device as a function of wavelength.
摘要翻译：一种用于确定光学装置的至少一个光学性质的方法包括提供光输入信号，该光输入信号包括分别在第一和第二频率被调制并分别具有第一和第二极化状态的第一和第二信号分量。光输入信号被传送到光学装置。来自光学装置的光输出信号分别分成具有第三和第四极化状态的第一和第二输出信号。第一和第二输出信号各自与第一和第二频率处的参考信号进行比较，以提供可用于确定作为波长的函数的光学器件的至少一个光学特性的四个相移和幅度测量。

5. 发明授权

US07265849B2 Systems and methods for determining the spectral content of an optical signal 失效
标题翻译：用于确定光信号的光谱含量的系统和方法
公开(公告)号：US07265849B2
公开(公告)日：2007-09-04
申请号：US10670538
申请日：2003-09-25
申请人： Mohan Gurunathan , William Ian McAlexander , Tun S. Tan
发明人： Mohan Gurunathan , William Ian McAlexander , Tun S. Tan
IPC分类号： G01B9/02
CPC分类号： G01J9/04
摘要： In one embodiment, a method determines the spectral content of an optical signal. Specifically, the optical signal and an optical local oscillator (LO) signal are provided to inputs of an optical hybrid (e.g., an N×N optical coupler where N is greater than two). The phase-diverse components from the optical hybrid are photodetected allowing for mixing of the optical signal and the optical local oscillator. Bandpass filtering is performed to eliminate or reduce relative intensity noise (RIN). The filtered signals are mixed with an electrical LO signal. A quadrature representation of a phase-diverse heterodyne signal is generated from signals from the mixing. The negative image and the positive image from the quadrature representation are separated. The spectral content of the optical signal is determined from the images.
摘要翻译：在一个实施例中，一种方法确定光信号的频谱内容。具体地，将光信号和光本地振荡器（LO）信号提供给光混合（例如，N大于2的NxN光耦合器）的输入。来自光学混合物的相位不同的分量被光电检测，允许光学信号和光学本地振荡器的混合。执行带通滤波以消除或减少相对强度噪声（RIN）。经滤波的信号与电LO信号混合。相位分集外差信号的正交表示由混合信号产生。来自正交表示的负像和正像被分离。根据图像确定光信号的光谱内容。

6. 发明授权

US07012697B2 Heterodyne based optical spectrum analysis with controlled optical attenuation 失效
标题翻译：基于Heterodyne的光谱分析，具有受控的光衰减
公开(公告)号：US07012697B2
公开(公告)日：2006-03-14
申请号：US10279436
申请日：2002-10-24
申请人： William Ian McAlexander , Douglas M. Baney
发明人： William Ian McAlexander , Douglas M. Baney
IPC分类号： G01B9/02
CPC分类号： G01J9/04 , G01J2001/0276
摘要： An optical heterodyne detection system includes an attenuator for attenuating an input signal before the input signal is combined with a local oscillator signal. An optimal attenuation level for the input signal, which improves the signal to noise ratio of the heterodyne beat signal, is determined by obtaining a base measurement of an output signal in response to the local oscillator signal and in the absence of the input signal, obtaining sample measurements of the output signal in response to the input signal as a function of different attenuation levels, and determining the optimal attenuation level as a function of the base measurement and the sample measurements. A minimum attenuation level for the input signal, which protects receiver photodetectors from being saturated or damaged, is determined by setting an initial attenuation level and gradually reducing the attenuation level until the voltage limit of the photodetectors is reached.
摘要翻译：光外差检测系统包括用于在输入信号与本地振荡器信号组合之前衰减输入信号的衰减器。通过获得响应于本地振荡器信号的输出信号的基本测量并且在不存在输入信号的情况下获得用于提高外差拍信号的信噪比的输入信号的最佳衰减电平，获得作为响应于作为不同衰减水平的函数的输入信号的输出信号的采样测量，以及确定作为基本测量和样本测量的函数的最佳衰减水平。通过设置初始衰减电平并逐渐减小衰减电平来确定保护接收机光电探测器不被饱和或损坏的输入信号的最小衰减电平直到达到光电检测器的电压极限。

7. 发明授权

US06744791B2 Rare earth-doped medium with photorefractive grating as compact laser source 失效
$Rare earth-doped medium with photorefractive grating as compact laser source$
标题翻译：具有光折射光栅的稀土掺杂介质作为紧凑的激光源
公开(公告)号：US06744791B2
公开(公告)日：2004-06-01
申请号：US10097690
申请日：2002-03-12
申请人： William Ian McAlexander , Douglas M. Baney , Mark Andrew Troll
发明人： William Ian McAlexander , Douglas M. Baney , Mark Andrew Troll
IPC分类号： H01S310
CPC分类号： H01S3/08009 , H01S3/0604 , H01S3/06754 , H01S3/0812 , H01S3/1055 , H01S3/1603 , H01S3/17
摘要： A compact, broadband laser source is realized by using a rare earth dopant to define a laser gain spectrum and by using holographic imprinting techniques to form a wavelength selection element for selecting a particular wavelength from within the gain spectrum. Artificial broadening of the gain spectrum can be achieved by establishing varied (e.g., randomized) domains of space charge within a rare earth-doped laser gain medium. Compactness can be enhanced by fabricating the laser gain medium and wavelength selection elements within a single member, such as a photorefractive crystal substrate. Flexibility in the selection of a wavelength can be obtained by holographically imprinting multiple sets of wavelength selection elements.
摘要翻译：通过使用稀土掺杂剂来定义激光增益谱并通过使用全息印记技术形成用于从增益谱内选择特定波长的波长选择元件来实现紧凑的宽带激光源。可以通过在稀土掺杂的激光增益介质内建立空间电荷的变化（例如，随机化）域来实现人造增宽增益谱。通过在单个构件（例如光折射晶体衬底）内制造激光增益介质和波长选择元件可以增强紧凑性。选择波长的灵活性可以通过全息印刷多组波长选择元件来获得。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式