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1. 发明申请

US20100058583A1 METHOD OF MANUFACTURING IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 有权
标题翻译：用于血压测量的可植入式无线传感器的制造方法
公开(公告)号：US20100058583A1
公开(公告)日：2010-03-11
申请号：US12612070
申请日：2009-11-04
申请人： Florent Cros , David O'Brien , Michael Fonseca , Matthew Abercrombie , Jin Woo Park , Angad Singh
发明人： Florent Cros , David O'Brien , Michael Fonseca , Matthew Abercrombie , Jin Woo Park , Angad Singh
IPC分类号： H01R43/00 , H05K1/16 , H01L21/20
CPC分类号： A61B5/0215 , A61B5/02055 , A61B5/6882 , A61B2562/0247 , A61B2562/12 , A61N1/36564 , H05K3/32 , Y10T29/49117 , Y10T29/4913
摘要： A method of manufacturing a sensor for in vivo applications includes the steps of providing two wafers of an electrically insulating material. A recess is formed in the first wafer, and a capacitor plate is formed in the recess of the first wafer. A second capacitor plate is formed in a corresponding region of the second wafer, and the two wafers are affixed to one another such that the first and second capacitor plates are arranged in parallel, spaced-apart relation.
摘要翻译：制造用于体内应用的传感器的方法包括提供电绝缘材料的两个晶片的步骤。在第一晶片中形成凹部，并且在第一晶片的凹部中形成电容器板。第二电容器板形成在第二晶片的相应区域中，并且两个晶片彼此固定，使得第一和第二电容器板以平行且间隔的关系布置。

2. 发明申请

US20100022896A1 VENTRICULAR SHUNT SYSTEM AND METHOD 有权
标题翻译：通气管系统及方法
公开(公告)号：US20100022896A1
公开(公告)日：2010-01-28
申请号：US12509053
申请日：2009-07-24
申请人： Jay Yadav , Florent Cros
发明人： Jay Yadav , Florent Cros
IPC分类号： A61B5/0215 , G01R27/26
CPC分类号： G01F15/066 , A61B5/0031 , A61B5/031 , A61B5/05 , A61B5/076 , A61B5/6846 , A61B2560/0219 , A61B2560/0223 , A61M27/006 , G01R23/12 , G01R23/145 , H01Q7/00
摘要： A ventricular shunt systems and methods of preventing hydrocephalus are described herein. In one aspect, the ventricular shunt system has at least one pressure sensor that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and is variable in response to the pressure in a patient's ventricle.
摘要翻译：本文描述了心室分流系统和预防脑积水的方法。在一个方面，心室分流系统具有至少一个压力传感器，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于患者心室中的压力是可变的。

3. 发明授权

US07647836B2 Hermetic chamber with electrical feedthroughs 有权
标题翻译：具有电馈通的气密室
公开(公告)号：US07647836B2
公开(公告)日：2010-01-19
申请号：US11748803
申请日：2007-05-15
申请人： David O'Brien , Christophe Courcimault , Liang You , Mark Allen , Michael Fonseca , Florent Cros
发明人： David O'Brien , Christophe Courcimault , Liang You , Mark Allen , Michael Fonseca , Florent Cros
IPC分类号： G01L7/00
CPC分类号： G01L9/0075 , G01L9/0042 , G01L9/0055 , Y10T29/49002
摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.
摘要翻译：压力腔是耐用的，稳定的和生物相容的并且被配置成使得其构成微微至纳升级体积的量。压力腔与外部环境密封，同时保持与其他设备通信的能力。微加工的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力并返回信息。设置在其中的压力腔和传感器部件与环境密封，以便减少传感器内的漂移和不稳定性。传感器设计用于苛刻和生物环境，例如体内植入和体内使用。另外，采用新的制造方法构造传感器。

4. 发明申请

US20090278553A1 SYSTEM AND APPARATUS FOR IN-VIVO ASSESSMENT OF RELATIVE POSITION OF AN IMPLANT 有权
标题翻译：用于内生植入物相对位置的体内评估的系统和装置
公开(公告)号：US20090278553A1
公开(公告)日：2009-11-12
申请号：US12416904
申请日：2009-04-01
申请人： Jason Kroh , Florent Cros , Christophe Courcimault
发明人： Jason Kroh , Florent Cros , Christophe Courcimault
IPC分类号： G01R27/04 , G01R27/28
CPC分类号： A61B5/055 , A61B5/0031 , A61B5/05 , A61B5/076 , A61B5/4514 , A61B2560/0219 , A61B2560/0223 , H01Q7/00
摘要： A system and apparatus for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.
摘要翻译：提供了一种用于提供对位于生物体内的植入物的相对运动的体内评估的系统和装置，其包括位于生物体内的第一组件和第二组件。第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于第一组件和第二组件在电磁耦合时。

5. 发明申请

US20080092663A1 Method and Apparatus for Measuring Pressure Inside a Fluid System 失效
标题翻译：用于测量流体系统内压力的方法和装置
公开(公告)号：US20080092663A1
公开(公告)日：2008-04-24
申请号：US11876252
申请日：2007-10-22
申请人： Kevin Corcoran , Florent Cros , Miguel Berr
发明人： Kevin Corcoran , Florent Cros , Miguel Berr
IPC分类号： G01L7/00
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/0215
摘要： A disclosed method determines fluid pressure inside a vessel without compromising the integrity of the vessel. A sensor is positioned in operative communication with the external wall of the vessel such that expansion of the external wall of the vessel exerts a force against the sensor that is directed substantially radially outward with respect to the vessel. A substantially radially inward force is caused to be directed against the sensor in response to the substantially radially outward force exerted by the external vessel wall. The sensor can thus be used to detect the magnitude of the substantially radially outward force. A disclosed apparatus determines fluid pressure inside a vessel without compromising the integrity of the vessel. The apparatus includes a sensor and a band operatively associated with the sensor and configured to at least partially encircle the vessel so as to retain the sensor in operative communication against the external wall of the vessel.
摘要翻译：所公开的方法确定容器内的流体压力而不损害容器的完整性。传感器被定位成与容器的外壁可操作地连通，使得容器的外壁的膨胀对传感器施加相对于容器大致径向向外的力。响应于由外部血管壁施加的基本径向向外的力，基本上径向向内的力被引导抵靠传感器。因此，传感器可用于检测基本径向向外的力的大小。所公开的装置确定容器内的流体压力而不损害容器的完整性。该装置包括传感器和与传感器可操作地相关联的带，其被构造成至少部分地环绕容器，以便将传感器保持在与血管的外壁有效连通。

6. 发明授权

US09041416B2 Physical property sensor with active electronic circuit and wireless power and data transmission 有权
标题翻译：具有有源电子电路和无线电力和数据传输的物理性能传感器
公开(公告)号：US09041416B2
公开(公告)日：2015-05-26
申请号：US13588518
申请日：2012-08-17
申请人： Jin Woo Park , Florent Cros , Mark G. Allen
发明人： Jin Woo Park , Florent Cros , Mark G. Allen
IPC分类号： A61B19/00 , A61B5/00 , H02J7/02
CPC分类号： H02J50/00 , A61B5/0031 , A61B2560/0219 , G01K13/00 , G01L1/00 , G01L7/00 , H02J5/005 , H02J7/025
摘要： Wireless sensors configured to record and transmit data as well as sense and, optionally, actuate to monitor physical properties of an environment and, optionally, effect changes within that environment. In one aspect, the wireless sensor can have a power harvesting unit; a voltage regulation unit, a transducing oscillator unit, and a transmitting coil. The voltage regulation unit is electrically coupled to the power harvesting unit and is configured to actuate at a minimum voltage level. The transducing oscillator unit is electrically coupled to the voltage regulation unit and is configured to convert a sensed physical property into an electrical signal. Also, the transmitting coil is configured to receive the electrical signal and to transmit the electrical signal to an external antenna.
摘要翻译：无线传感器被配置为记录和传输数据以及感测和可选地启动以监视环境的物理特性，并且可选地影响该环境内的改变。一方面，无线传感器可以具有电力收集单元; 电压调节单元，换能振荡器单元和发送线圈。电压调节单元电耦合到功率采集单元并且被配置为在最小电压电平下致动。转换振荡器单元电耦合到电压调节单元，并且被配置为将检测到的物理特性转换成电信号。此外，发送线圈被配置为接收电信号并将电信号发送到外部天线。

7. 发明授权

US08278941B2 Strain monitoring system and apparatus 有权
标题翻译：应变监测系统及仪器
公开(公告)号：US08278941B2
公开(公告)日：2012-10-02
申请号：US12416916
申请日：2009-04-01
申请人： Jason Kroh , Florent Cros , Christophe Courcimault
发明人： Jason Kroh , Florent Cros , Christophe Courcimault
IPC分类号： G01R27/02
CPC分类号： G01L9/0073 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/4504 , A61B5/686 , A61B17/7002 , A61B2017/00221 , A61B2560/0219 , A61B2560/0223 , A61B2562/0261 , G01F15/066 , G01L1/14 , H01Q7/00
摘要： This application relates to an apparatus and system for sensing strain on a portion of an implant positioned in a living being. In one aspect, the apparatus has at least one sensor assembly that can be mountable thereon a portion of the implant and that has a passive electrical resonant circuit that can be configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy. Each sensor assembly, in response to the electromagnetic coupling, can be configured to generate an output signal characterized by a frequency that is dependent upon urged movement of a portion of the passive electrical resonant circuit and is indicative of strain applied thereon a portion of the respective sensor assembly.
摘要翻译：本申请涉及用于感测定位在生物体内的植入物的一部分上的应变的装置和系统。在一个方面，该装置具有至少一个传感器组件，其可以安装在其上的植入物的一部分上，并且具有无源电谐振电路，其可被配置为选择性地电磁耦合到离体RF能量源。响应于电磁耦合，每个传感器组件可被配置成产生一个输出信号，该输出信号的特征在于取决于被动电谐振电路的一部分被推动的移动的频率，并且指示施加在其上的相应的一部分的应变传感器组件。

8. 发明授权

US08264240B2 Physical property sensor with active electronic circuit and wireless power and data transmission 有权
标题翻译：具有有源电子电路和无线电力和数据传输的物理性能传感器
公开(公告)号：US08264240B2
公开(公告)日：2012-09-11
申请号：US12506170
申请日：2009-07-20
申请人： Jin Woo Park , Florent Cros , Mark G. Allen
发明人： Jin Woo Park , Florent Cros , Mark G. Allen
IPC分类号： G01R27/28
CPC分类号： H02J50/00 , A61B5/0031 , A61B2560/0219 , G01K13/00 , G01L1/00 , G01L7/00 , H02J5/005 , H02J7/025
摘要： Wireless sensors configured to record and transmit data as well as sense and, optionally, actuate to monitor physical properties of an environment and, optionally, effect changes within that environment. In one aspect, the wireless sensor can have a power harvesting unit; a voltage regulation unit, a transducing oscillator unit, and a transmitting coil. The voltage regulation unit is electrically coupled to the power harvesting unit and is configured to actuate at a minimum voltage level. The transducing oscillator unit is electrically coupled to the voltage regulation unit and is configured to convert a sensed physical property into an electrical signal. Also, the transmitting coil is configured to receive the electrical signal and to transmit the electrical signal to an external antenna.
摘要翻译：无线传感器被配置为记录和传输数据以及感测和可选地启动以监视环境的物理特性，并且可选地影响该环境内的改变。一方面，无线传感器可以具有电力收集单元; 电压调节单元，换能振荡器单元和发送线圈。电压调节单元电耦合到功率采集单元并且被配置为在最小电压电平下致动。转换振荡器单元电耦合到电压调节单元，并且被配置为将检测到的物理特性转换成电信号。此外，发送线圈被配置为接收电信号并将电信号发送到外部天线。

9. 发明授权

US08026729B2 System and apparatus for in-vivo assessment of relative position of an implant 有权
标题翻译：用于体内评估植入物的相对位置的系统和装置
公开(公告)号：US08026729B2
公开(公告)日：2011-09-27
申请号：US12416904
申请日：2009-04-01
申请人： Jason Kroh , Florent Cros , Christophe Courcimault
发明人： Jason Kroh , Florent Cros , Christophe Courcimault
IPC分类号： G01R27/04
CPC分类号： A61B5/055 , A61B5/0031 , A61B5/05 , A61B5/076 , A61B5/4514 , A61B2560/0219 , A61B2560/0223 , H01Q7/00
摘要： A system and apparatus for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that includes a first assembly and a second assembly that are positioned within the living being. The first assembly includes a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.
摘要翻译：提供了一种用于提供定位在生活中的植入物的相对运动的体内评估的系统和装置，其包括位于生物体内的第一组件和第二组件。第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于第一组件和第二组件在电磁耦合时。

10. 发明申请

US20110115497A1 SELECTIVELY ACTUATING WIRELESS, PASSIVE IMPLANTABLE SENSOR 有权
标题翻译：选择无线，无源可插入传感器
公开(公告)号：US20110115497A1
公开(公告)日：2011-05-19
申请号：US12946407
申请日：2010-11-15
申请人： FLORENT CROS
发明人： FLORENT CROS
IPC分类号： G01R35/00 , G01R27/04 , G06F19/00
CPC分类号： A61B5/0031 , A61B2560/0219
摘要： A wireless sensor having a primary passive electrical resonant circuit that has an intrinsic electrical property that is variable in response to a characteristic of a patient and a secondary passive electrical resonant circuit. In one aspect, the primary passive resonant circuit can be positioned into a tuned position in response to the actuation of the secondary passive electrical resonant circuit. In a further aspect, in the tuned position, the primary passive electrical resonant circuit, in response to an energizing signal produced by an ex-vivo source of RF energy, is configured to generate a sensor signal characterized by a resonant frequency that is indicative of the characteristic.
摘要翻译：一种无线传感器，其具有主无源电谐振电路，其具有响应于患者的特性和次级无源电谐振电路而变化的本征电特性。在一个方面，主无源谐振电路可以响应于辅助无源电谐振电路的致动而被定位到调谐位置。在另一方面，在调谐位置中，主无源电谐振电路响应于由RF能量的离体源产生的激励信号，被配置为产生以共振频率为特征的传感器信号，该谐振频率指示的特点。

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