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1. 发明授权

US08492365B2 7-substituted tetracycline compounds 有权
公开(公告)号：US08492365B2
公开(公告)日：2013-07-23
申请号：US12481368
申请日：2009-06-09
申请人： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
发明人： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
IPC分类号： A61K31/65 , A61K31/42 , A61K31/426 , A61K31/4402 , A61K31/505 , A61K31/5375 , C07C237/26 , C07D239/26 , C07D295/104 , C07D261/08 , C07D277/42
CPC分类号： C07D213/64 , C07C237/26 , C07C251/24 , C07C251/48 , C07C271/22 , C07C271/28 , C07C271/58 , C07C275/24 , C07C311/06 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2603/46 , C07D207/22 , C07D213/50 , C07D213/56 , C07D239/36 , C07D261/18 , C07D277/30 , C07D277/42 , C07D295/096 , C07D295/135 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/28 , C07D333/60 , C07F9/2475
摘要： The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

2. 发明申请

US20090306022A1 7-SUBSTITUTED TETRACYCLINE COMPOUNDS 有权
标题翻译： 7-取代的四环素化合物
公开(公告)号：US20090306022A1
公开(公告)日：2009-12-10
申请号：US12481368
申请日：2009-06-09
申请人： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
发明人： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
IPC分类号： A61K31/65 , C07C237/26 , C07D277/38 , C07D333/24 , C07D213/56 , C07D307/54 , C07D239/52 , C07D413/06 , C07D239/34
CPC分类号： C07D213/64 , C07C237/26 , C07C251/24 , C07C251/48 , C07C271/22 , C07C271/28 , C07C271/58 , C07C275/24 , C07C311/06 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2603/46 , C07D207/22 , C07D213/50 , C07D213/56 , C07D239/36 , C07D261/18 , C07D277/30 , C07D277/42 , C07D295/096 , C07D295/135 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/28 , C07D333/60 , C07F9/2475
摘要： The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
摘要翻译：本发明至少部分地涉及新的7-取代四环素化合物。这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。

3. 发明申请

US20090035633A1 Chemically sintered composite electrodes and manufacturing processes 有权
标题翻译：化学烧结复合电极及制造工艺
公开(公告)号：US20090035633A1
公开(公告)日：2009-02-05
申请号：US11888943
申请日：2007-08-03
申请人： John Rule , Samuel B. Schaevitz , Zachary Byars , Ramanan Ganeshananthan , Atul Verma , Vladimir Petrovsky
发明人： John Rule , Samuel B. Schaevitz , Zachary Byars , Ramanan Ganeshananthan , Atul Verma , Vladimir Petrovsky
IPC分类号： H01M8/10 , B05D5/12 , B32B5/16
CPC分类号： H01M8/1213 , H01M4/8652 , H01M4/8657 , H01M4/8828 , H01M4/8885 , H01M8/1004 , H01M8/1097 , H01M8/1246 , H01M8/1286 , Y02E60/521 , Y02E60/525 , Y02P70/56 , Y10T428/25
摘要： An iterative process of depositing on a solid electrolyte a coating of unconnected particles composed of an ionically conductive material. A liquid solution is also applied. The liquid solution includes an inorganic component. The deposited liquid is heated to a temperature sufficient to evaporate or otherwise remove some or all of the volatile components of the liquid solution. Typically the temperature is below 1000° and often at about 850° C. The effect of heating the solution is to cause ion conducting material in the solution to adhere to the surface of the existing ion conducting particles and form connections between these particles. This is understood to create an ion conducting skeletal support structure. Within the intrestices of this skeletal support structure, the step of heating is also understood to result in the deposition of the inorganic component that will begin to form a electron conducting structure. The process of applying the liquid solution and heating may be repeated until a sufficiently thick layer of material is laid over the solid electrolyte to provide the composite electrode structure desired.
摘要翻译：在固体电解质上沉积由离子导电材料组成的未连接颗粒的涂层的迭代过程。还应用液体溶液。液体溶液包含无机成分。将沉积的液体加热到足以蒸发或以其它方式除去液体溶液的一些或全部挥发性组分的温度。通常，温度低于1000°，通常在约850℃。加热溶液的效果是使溶液中的离子传导材料粘附到现有离子传导颗粒的表面上并形成这些颗粒之间的连接。这被理解为产生离子导电骨架支撑结构。在该骨骼支撑结构的内部，加热步骤也被理解为导致开始形成电子传导结构的无机组分的沉积。可以重复施加液体溶液和加热的过程，直到将足够厚的材料层铺在固体电解质上以提供所需的复合电极结构。

5. 发明申请

US20050124678A1 Transcription factor modulating compounds and methods of use thereof 有权
标题翻译：转录因子调节化合物及其使用方法
公开(公告)号：US20050124678A1
公开(公告)日：2005-06-09
申请号：US10700661
申请日：2003-11-03
申请人： Stuart Levy , Michael Alekshun , Brent Podlogar , Kwasi Ohemeng , Atul Verma , Tadeusz Warchol , Beena Bhatia , Todd Bowser , Mark Grier
发明人： Stuart Levy , Michael Alekshun , Brent Podlogar , Kwasi Ohemeng , Atul Verma , Tadeusz Warchol , Beena Bhatia , Todd Bowser , Mark Grier
IPC分类号： A61K31/40 , A61K31/407 , A61K31/41 , A61K31/415 , A61K31/42 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/4745 , A61K31/495 , A61K31/50 , A61K31/505 , A61K31/535 , A61K31/55 , A61K31/555 , A61K31/4184
CPC分类号： A61K31/40 , A61K31/407 , A61K31/41 , A61K31/415 , A61K31/42 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/4745 , A61K31/495 , A61K31/50 , A61K31/505 , A61K31/535 , A61K31/55 , A61K31/555 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
摘要： Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
摘要翻译：提供了可用作降低微生物的抗性，毒力或生长的抗感染药物的取代的苯并咪唑化合物。制备和使用取代的苯并咪唑化合物的方法，以及其药物制剂，例如降低抗生素抗性和抑制生物膜。

6. 发明申请

US20050038002A1 Substituted tetracycline compounds 有权
标题翻译：取代四环素化合物
公开(公告)号：US20050038002A1
公开(公告)日：2005-02-17
申请号：US10740961
申请日：2003-12-18
申请人： Mark Nelson , Kwasi Ohemeng , Roger Frechette , Paul Abato , Victor Amoo , Upul Bandarage , Joel Berniac , Beena Bhatia , Jackson Chen , Mohamed Ismail , Oak Kim , Laura Honeyman , Rachid Mechiche , Andre Pearson , Laxma Nagavelli , Paul Sheahan , Atul Verma , Peter Viski , Tadeusz Warchol
发明人： Mark Nelson , Kwasi Ohemeng , Roger Frechette , Paul Abato , Victor Amoo , Upul Bandarage , Joel Berniac , Beena Bhatia , Jackson Chen , Mohamed Ismail , Oak Kim , Laura Honeyman , Rachid Mechiche , Andre Pearson , Laxma Nagavelli , Paul Sheahan , Atul Verma , Peter Viski , Tadeusz Warchol
IPC分类号： C07D295/20 , A61K31/65 , A61P31/04 , A61P43/00 , C07C237/26 , C07C239/18 , C07C245/20 , C07C251/08 , C07C251/48 , C07C255/25 , C07C255/43 , C07C255/58 , C07C255/59 , C07C271/28 , C07C271/44 , C07C275/34 , C07C279/18 , C07C281/14 , C07C309/61 , C07C311/06 , C07C311/19 , C07C311/21 , C07C317/48 , C07C323/32 , C07C323/60 , C07D207/16 , C07D211/58 , C07D213/30 , C07D213/61 , C07D213/65 , C07D213/75 , C07D239/26 , C07D239/30 , C07D239/42 , C07D261/10 , C07D261/18 , C07D295/108 , C07D295/155 , C07D295/215 , C07D307/28 , C07D307/52 , C07D307/54 , C07D307/68 , C07D317/54 , C07D317/60 , C07D401/04 , C07F7/10
CPC分类号： C07D307/52 , C07C237/26 , C07C239/18 , C07C251/08 , C07C251/48 , C07C255/25 , C07C255/43 , C07C255/58 , C07C255/59 , C07C271/28 , C07C271/44 , C07C275/34 , C07C279/18 , C07C281/14 , C07C309/61 , C07C311/19 , C07C311/21 , C07C317/48 , C07C323/32 , C07C323/60 , C07C2603/46 , C07D207/16 , C07D211/58 , C07D213/30 , C07D213/61 , C07D213/65 , C07D213/75 , C07D239/26 , C07D239/30 , C07D239/42 , C07D261/10 , C07D261/18 , C07D295/108 , C07D295/155 , C07D295/215 , C07D307/28 , C07D307/68 , C07D317/54 , C07D401/04
摘要： The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
摘要翻译：本发明至少部分地涉及新的取代的四环素化合物。这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。

7. 发明授权

US09583778B2 Chemically sintered composite electrodes and manufacturing processes 有权
标题翻译：化学烧结复合电极及制造工艺
公开(公告)号：US09583778B2
公开(公告)日：2017-02-28
申请号：US11888943
申请日：2007-08-03
申请人： Samuel B. Schaevitz , Zachary Byars , Ramanan Ganeshananthan , Atul Verma , John Rule
发明人： Samuel B. Schaevitz , Zachary Byars , Ramanan Ganeshananthan , Atul Verma , Vladimir Petrovsky , John Rule
IPC分类号： H01M8/1213 , H01M8/1286 , H01M8/1004 , H01M8/1097 , H01M8/1246 , H01M8/12 , H01M4/86 , H01M4/88 , H01M8/10
CPC分类号： H01M8/1213 , H01M4/8652 , H01M4/8657 , H01M4/8828 , H01M4/8885 , H01M8/1004 , H01M8/1097 , H01M8/1246 , H01M8/1286 , Y02E60/521 , Y02E60/525 , Y02P70/56 , Y10T428/25
摘要： An iterative process of depositing on a solid electrolyte a coating of unconnected particles composed of an ionically conductive material. A liquid solution is also applied. The liquid solution includes an inorganic component. The deposited liquid is heated to a temperature sufficient to evaporate or otherwise remove some or all of the volatile components of the liquid solution. Typically the temperature is below 1000° and often at about 850° C. The effect of heating the solution is to cause ion conducting material in the solution to adhere to the surface of the existing ion conducting particles and form connections between these particles. This is understood to create an ion conducting skeletal support structure. Within the intrestices of this skeletal support structure, the step of heating is also understood to result in the deposition of the inorganic component that will begin to form a electron conducting structure. The process of applying the liquid solution and heating may be repeated until a sufficiently thick layer of material is laid over the solid electrolyte to provide the composite electrode structure desired.
摘要翻译：在固体电解质上沉积由离子导电材料组成的未连接颗粒的涂层的迭代过程。还应用液体溶液。液体溶液包含无机成分。将沉积的液体加热到足以蒸发或以其它方式除去液体溶液的一些或全部挥发性组分的温度。通常，温度低于1000°，通常在约850℃。加热溶液的效果是使溶液中的离子传导材料粘附到现有离子传导颗粒的表面上并形成这些颗粒之间的连接。这被理解为产生离子导电骨架支撑结构。在该骨骼支撑结构的内部，加热步骤也被理解为导致开始形成电子传导结构的无机组分的沉积。可以重复施加液体溶液和加热的过程，直到将足够厚的材料层铺在固体电解质上以提供所需的复合电极结构。

8. 发明授权

US07681012B2 Method, system and device for handling a memory management fault in a multiple processor device 有权
标题翻译：用于处理多处理器设备中的存储器管理故障的方法，系统和设备
公开(公告)号：US07681012B2
公开(公告)日：2010-03-16
申请号：US11699562
申请日：2007-01-30
申请人： Atul Verma , Samant Kumar
发明人： Atul Verma , Samant Kumar
IPC分类号： G06F13/00
CPC分类号： G06F12/10 , G06F2212/1032
摘要： A method or device handles memory management faults in a device having a digital signal processor (“DSP”) and a microprocessor. The DSP includes a memory management unit (“DSP MMU”) to manage memory access by the DSP, and the DSP and the microprocessor access shared physical memory. Upon the DSP executing an instruction attempting to access a virtual address wherein the virtual address is invalid, a page fault interrupt is generated by the DSP MMU. A microprocessor interrupt handler in the microprocessor is activated in direct response to the page fault interrupt. Thereafter in the microprocessor, a translation lookaside buffer (“TLB”) entry is created in the DSP MMU, which includes a valid mapping between the virtual address and a page of physical memory. After creating the TLB entry, the microprocessor indicates to the DSP that the access by the DSP of the virtual address is completed.
摘要翻译：方法或设备处理具有数字信号处理器（“DSP”）和微处理器的设备中的存储器管理故障。 DSP包括一个内存管理单元（“DSP MMU”），用于管理DSP的存储器访问，DSP和微处理器访问共享的物理内存。在DSP执行试图访问虚拟地址无效的虚拟地址的指令时，由DSP MMU产生寻呼故障中断。微处理器中的微处理器中断处理程序是直接响应页错误中断而被激活的。此后在微处理器中，在DSP MMU中创建翻译后备缓冲器（“TLB”）条目，其包括虚拟地址和物理存储器页之间的有效映射。在创建TLB条目之后，微处理器向DSP指示DSP访问虚拟地址。

9. 外观设计

USD919026S1 Skateboard chassis system with battery for a three-wheeler electric vehicle 有权
公开(公告)号：USD919026S1
公开(公告)日：2021-05-11
申请号：US29734940
申请日：2020-05-16
申请人： Saurav Kumar , Atul Verma , Kundan Kumar , Aditya Baburajan
设计人： Saurav Kumar , Atul Verma , Kundan Kumar , Aditya Baburajan

10. 发明申请

US20070134540A1 SOLID OXIDE ELECTROCHEMICAL DEVICES HAVING A DIMENSIONALLY STABLE BONDING AGENT TO BOND AN ANODE TO ANODE INTERCONNECT AND METHODS 审中-公开
标题翻译：具有尺寸稳定的粘结剂的固体氧化物电化学装置将阳极粘合到阳极互连和方法
公开(公告)号：US20070134540A1
公开(公告)日：2007-06-14
申请号：US11164941
申请日：2005-12-12
申请人： Atul Verma , Shekhar Kamat
发明人： Atul Verma , Shekhar Kamat
IPC分类号： H01M2/08 , H01M8/12
CPC分类号： H01M8/0273 , H01M8/0217 , H01M8/0247 , H01M8/0282 , H01M2008/1293 , Y10T29/49114
摘要： A solid oxide electrochemical device having improved mechanical integrity comprising a bonding agent for physically and electrically bonding an anode to an anode interconnect, the bonding agent comprising a particulate metal, wherein the bonding agent is substantially chemically inert during operation of the solid oxide electrochemical device. A method for bonding an anode and an anode interconnect to be used in a solid oxide electrochemical device.
摘要翻译：一种具有改进的机械完整性的固体氧化物电化学装置，其包括用于将阳极物理和电连接到阳极互连的粘合剂，所述粘合剂包含颗粒状金属，其中所述粘合剂在固体氧化物电化学装置的操作期间基本上是化学惰性的。用于将固体氧化物电化学装置中使用的阳极和阳极互连件接合的方法。

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