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1. 发明授权

US08699775B2 Magnetic resonance system and method to determine an image data set that describes a temperature distribution in a subject 失效
标题翻译：磁共振系统和确定描述受试者温度分布的图像数据集的方法
公开(公告)号：US08699775B2
公开(公告)日：2014-04-15
申请号：US13217505
申请日：2011-08-25
申请人： Joerg Roland , Sebastian Schmidt , Anke Weissenborn
发明人： Joerg Roland , Sebastian Schmidt , Anke Weissenborn
IPC分类号： G06K9/00
CPC分类号： G01R33/4804 , A61B5/015 , A61B5/055 , G06T7/0014 , G06T2207/10088 , G06T2207/30196
摘要： In a magnetic resonance method and apparatus to determine an examination image data set describing the temperature distribution within an examination subject (in particular a patient) using magnetic resonance an absolute temperature image data set of an examination region of the subject is acquired by magnetic resonance temperature imaging, a normal temperature data set of the examination region is determined, and the examination image data set is determined in a computerized processor by a comparison of the absolute temperature image data set with the normal temperature data set.
摘要翻译：在使用磁共振来确定检查对象（特别是患者）内的温度分布的检查图像数据集的磁共振方法和装置中，通过磁共振温度获取被检体的检查区域的绝对温度图像数据集确定检查区域的常温数据组，并且通过比较绝对温度图像数据与常温数据组的比较，在计算机化处理器中确定检查图像数据集。

2. 发明申请

US20110144475A1 METHOD FOR A REGULATION OF A VASCULAR INTERVENTION, AND DEVICE TO REGULATE A VASCULAR INTERVENTION 审中-公开
标题翻译：用于调节血管干预的方法和调节血管干预的装置
公开(公告)号：US20110144475A1
公开(公告)日：2011-06-16
申请号：US12964880
申请日：2010-12-10
申请人： Okan Ekinci , Friedrich Fuchs , Markus Schmidt , Sebastian Schmidt , Anke Weissenborn
发明人： Okan Ekinci , Friedrich Fuchs , Markus Schmidt , Sebastian Schmidt , Anke Weissenborn
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/02007 , A61B6/481 , A61B6/504 , A61B6/507 , A61B8/00 , A61B2090/374 , A61M5/007
摘要： In a method and apparatus to regulate a vessel intervention conducted with a vessel intervention unit, wherein an intervention region of the vessel intervention is at least partially imaged by means of an imaging monitoring unit, and a monitoring region to monitor the vessel intervention is selected, and the vessel intervention is at least partially automatically regulated in the intervention region dependent on at least one characteristic variable identified in the monitoring region.
摘要翻译：在用容器介入单元进行血管干预调节的方法和装置中，其中血管干预的干预区域通过成像监测单元至少部分成像，并且选择监测血管干预的监测区域，并且根据在监测区域中识别的至少一个特征变量，血管干预至少部分地在干预区域中自动调节。

3. 发明申请

US20100286511A1 METHOD FOR DISPLAYING IMAGE DATA OF A PART OF A PATIENT'S BODY 审中-公开
标题翻译：用于显示患者身体部位的图像数据的方法
公开(公告)号：US20100286511A1
公开(公告)日：2010-11-11
申请号：US12774876
申请日：2010-05-06
申请人： Swen WOERLEIN , Anke Weissenborn , Ingmar Thiemann , Martin Mathis
发明人： Swen WOERLEIN , Anke Weissenborn , Ingmar Thiemann , Martin Mathis
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/06 , A61B5/064 , A61B5/7445 , A61B34/20 , A61B90/39 , A61B2090/3941 , G01N21/6428 , G01N21/6456
摘要： The invention relates to a method for displaying image data of a part of a patient's body, in which the part of the patient's body comprising regions which are provided with a radiation-emitting contrast agent is detected in a first step by means of a detection device, wherein during the first step, the intensity of the radiation emitted by the regions provided with the contrast agent is higher than the intensity of other radiation which can be detected by the detection device and which is emitted by the detected part of the patient's body, wherein a patient image data set is produced on the basis of the detected radiation, and wherein the patient image data set is displayed to a user by means of an output device in a second step. The invention also relates to a device for displaying image data of a part of a patient's body, comprising: a detection device which comprises at least one camera for detecting radiation emitted by regions of the part of the patient's body which are provided with a radiation-emitting contrast agent; a computational unit which produces a patient image data set on the basis of the images detected by the detection device; and an output device for displaying the patient image data set produced.
摘要翻译：本发明涉及一种用于显示患者身体的一部分的图像数据的方法，其中通过检测装置在第一步骤中检测包括设置有辐射发射造影剂的区域的患者身体的部分其中，在所述第一步骤期间，由所述造影剂设置的区域发射的辐射的强度高于由所述检测装置检测并由所述检测到的所述患者身体发出的其他辐射的强度，其中，基于所检测的辐射产生患者图像数据组，并且其中所述患者图像数据集在第二步骤中借助于输出装置显示给用户。本发明还涉及一种用于显示患者身体的一部分的图像数据的装置，包括：检测装置，其包括用于检测由患者身体的该部分区域发射的辐射的至少一个照相机，发射造影剂; 计算单元，其基于由所述检测装置检测到的图像产生患者图像数据集; 以及用于显示产生的患者图像数据集的输出装置。

4. 发明申请

US20100177185A1 SURGICAL MICROSCOPE WITH INTEGRATED STRUCTURED ILLUMINATION 审中-公开
标题翻译：具有一体化结构照明的手术显微镜
公开(公告)号：US20100177185A1
公开(公告)日：2010-07-15
申请号：US12664827
申请日：2007-06-18
申请人： Swen Woerlein , Ingmar Tiehmann , Martin Mathis , Anke Weissenborn
发明人： Swen Woerlein , Ingmar Tiehmann , Martin Mathis , Anke Weissenborn
IPC分类号： H04N7/18 , G06K9/00 , G02B21/06
CPC分类号： A61B90/36 , A61B34/20 , A61B90/20 , A61B2034/2055 , A61B2090/366 , A61B2090/3762
摘要： The application concerns a method of integrating image information (3, 5, 8, 9) from an external source, e.g. an imaging device (1), and an operating microscope (2) before or during an operative procedure on an object (18) or body parts of a patient comprising: positioning an operating microscope (2) before or in the course of said operative procedure at an operative location relative to the patient (18); establishing the spatial relationship among the image information, the patient (18), and the focal plane of a projector (7) or the projection space or the projector (7) itself; introducing the image information and spatial relationship to a computer and reformatting the image information to generate a computer-generated image of the body part at a determined area or plane related to or directly on the surface of the object (18); and projecting the computer-generated image onto the object (18) or patient for coordinated viewing (12) of the computer-generated image and the patient.
摘要翻译：该应用涉及一种从外部源（例如，图像信号）集成图像信息（3,5,8,9）的方法。成像装置（1）和操作显微镜（2），其在对象（18）或患者身体部位的手术过程之前或期间包括：在所述手术过程之前或过程中定位手术显微镜（2）在相对于患者（18）的操作位置处; 建立图像信息，患者（18）和投影仪（7）或投影空间或投影仪（7）本身的焦平面之间的空间关系; 将图像信息和空间关系引入计算机并重新格式化图像信息，以在与物体（18）的表面相关或直接在所述物体（18）的确定的区域或平面上生成身体部位的计算机生成的图像; 以及将所述计算机生成的图像投影到所述对象（18）或患者身上以协调地观看（12）所述计算机生成的图像和所述患者。

5. 发明申请

US20050196848A1 Process for the fermentative production of L-amino acids by attenuation of the poxB gene 审中-公开
标题翻译：通过痘痘基因的减毒发酵生产L-氨基酸的方法
公开(公告)号：US20050196848A1
公开(公告)日：2005-09-08
申请号：US11111831
申请日：2005-04-22
申请人： Nicole Dusch , Brigitte Bathe , Jorn Kalinowski , Alfred Puhler , Bettina Mockel , Anke Weissenborn , Walter Pfefferle
发明人： Nicole Dusch , Brigitte Bathe , Jorn Kalinowski , Alfred Puhler , Bettina Mockel , Anke Weissenborn , Walter Pfefferle
IPC分类号： C12N15/09 , C12N1/21 , C12N9/02 , C12N15/31 , C12N15/53 , C12P13/08 , C12R1/15 , C12Q1/68 , C07H21/04 , C12N1/20 , C12N9/10 , C12N15/74
CPC分类号： C12N9/0008
摘要： An isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b) and d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c), and a process for the fermentative production of L-amino acids by attenuation of the poxB gene.
摘要翻译：一种分离的多核苷酸，其含有多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码含有SEQ ID NO：1的氨基酸序列的多肽的多核苷酸至少70％相同。 2，b）编码多肽的多核苷酸，其含有与SEQ ID No：1的氨基酸序列至少70％相同的氨基酸序列。 2）c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）多核苷酸序列的至少15个连续碱基的多核苷酸，以及发酵生产L - 氨基酸通过减少poxB基因。

6. 发明申请

US20050100927A1 Nucleotide sequence encoding the dapC gene and process for the production of L-lysine 有权
标题翻译：编码dapC基因的核苷酸序列和生产L-赖氨酸的方法
公开(公告)号：US20050100927A1
公开(公告)日：2005-05-12
申请号：US10745684
申请日：2003-12-29
申请人： Bettina Mockel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jorn Kalinowski , Alfred Puhler
发明人： Bettina Mockel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jorn Kalinowski , Alfred Puhler
IPC分类号： C12N15/09 , C12N1/21 , C12N9/10 , C12N15/31 , C12N15/54 , C12P13/08 , C12Q1/68 , C12R1/13
CPC分类号： C12P13/08 , C12N9/1096
摘要： The invention relates to an isolated polynucleotide from coryneform bacteria containing at least one polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide which encodes a polypeptide containing the amino acid sequence according to SEQ ID no. 2, b) polynucleotide which encodes a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequences of a), b) or c), and to a process for the fermentative production of L-amino acids, in particular L-lysine.
摘要翻译：本发明涉及来自棒状细菌的分离的多核苷酸，其含有至少一种多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码含有根据SEQ ID No.3所述的氨基酸序列的多肽的多核苷酸至少70％相同。 2，b）编码多肽的多核苷酸，其含有与SEQ ID NO：1的氨基酸序列至少70％相同的氨基酸序列。 2）c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及d）发酵生产的方法的L-氨基酸，特别是L-赖氨酸。

7. 发明授权

US08779771B2 Magnetic resonance imaging system and method embodying a magnetic resonance marking system and method 失效
标题翻译：磁共振成像系统和方法体现了磁共振标记系统和方法
公开(公告)号：US08779771B2
公开(公告)日：2014-07-15
申请号：US13213253
申请日：2011-08-19
申请人： Bjoern Heismann , Sebastian Schmidt , Markus Vester , Anke Weissenborn
发明人： Bjoern Heismann , Sebastian Schmidt , Markus Vester , Anke Weissenborn
IPC分类号： G01V3/00
CPC分类号： A61B5/055 , A61B5/0263 , A61B5/4064
摘要： In a magnetic resonance marking system marking a flowing medium in a marking region, as well as in a magnetic resonance system with such a magnetic resonance marking system, a method to control a magnetic resonance marking system, and a method to generate magnetic resonance exposures, a radio-frequency transmission device generates marking radio-frequency signals, and a marking radio-frequency transmission coil emits the marking radio-frequency signals in the marking region. A magnetic field determination device determines a magnetic field strength in the marking region, and a control unit derives a marking transmission frequency from the determined magnetic field strength and to control the radio-frequency transmission device so that marking radio-frequency signals at the derived marking transmission frequency are emitted by the marking radio-frequency transmission coil.
摘要翻译：在标记区域中的流动介质的磁共振标记系统中，以及在具有这种磁共振标记系统的磁共振系统中，控制磁共振标记系统的方法和产生磁共振曝光的方法，射频发送装置生成标记射频信号，标记射频发送线圈在标记区域发出标记射频信号。磁场确定装置确定标记区域中的磁场强度，并且控制单元从确定的磁场强度导出标记传输频率，并且控制射频传输装置，从而在导出的标记处标记射频信号传输频率由标记射频发射线圈发射。

8. 发明申请

US20120043965A1 MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD EMBODYING A MAGNETIC RESONANCE MARKING SYSTEM AND METHOD 失效
标题翻译：磁共振成像系统及方法制作磁共振标记系统及方法
公开(公告)号：US20120043965A1
公开(公告)日：2012-02-23
申请号：US13213253
申请日：2011-08-19
申请人： BJOERN HEISMANN , SEBASTIAN SCHMIDT , MARKUS VESTER , ANKE WEISSENBORN
发明人： BJOERN HEISMANN , SEBASTIAN SCHMIDT , MARKUS VESTER , ANKE WEISSENBORN
IPC分类号： G01R33/48 , G01R33/341
CPC分类号： A61B5/055 , A61B5/0263 , A61B5/4064
摘要： In a magnetic resonance marking system marking a flowing medium in a marking region, as well as in a magnetic resonance system with such a magnetic resonance marking system, a method to control a magnetic resonance marking system, and a method to generate magnetic resonance exposures, a radio-frequency transmission device generates marking radio-frequency signals, and a marking radio-frequency transmission coil emits the marking radio-frequency signals in the marking region. A magnetic field determination device determines a magnetic field strength in the marking region, and a control unit derives a marking transmission frequency from the determined magnetic field strength and to control the radio-frequency transmission device so that marking radio-frequency signals at the derived marking transmission frequency are emitted by the marking radio-frequency transmission coil.
摘要翻译：在标记区域中的流动介质的磁共振标记系统中，以及在具有这种磁共振标记系统的磁共振系统中，控制磁共振标记系统的方法和产生磁共振曝光的方法，射频发送装置生成标记射频信号，标记射频发送线圈在标记区域发出标记射频信号。磁场确定装置确定标记区域中的磁场强度，并且控制单元从确定的磁场强度导出标记传输频率，并且控制射频传输装置，从而在导出的标记处标记射频信号传输频率由标记射频发射线圈发射。

9. 发明申请

US20110144484A1 METHOD AND DEVICE FOR MONITORING A MEDICAL PROCEDURE SUCH AS A VASCULAR SURGERY OPERATION 审中-公开
标题翻译：用于监测医疗程序如血管手术操作的方法和装置
公开(公告)号：US20110144484A1
公开(公告)日：2011-06-16
申请号：US12964868
申请日：2010-12-10
申请人： Sebastian Schmidt , Anke Weissenborn
发明人： Sebastian Schmidt , Anke Weissenborn
IPC分类号： A61B5/05
CPC分类号： A61B5/0263 , A61B5/0275 , A61B5/055 , A61B5/4839 , A61B6/481 , A61B6/504 , G01R33/56333 , G01R33/56341 , G01R33/5635 , G01R33/56366
摘要： In a monitoring method and device for monitoring a medical procedure, in particular a vascular surgery operation, at least one monitoring measurement in a monitoring region is acquired by a medical imaging device, and the at least one monitoring measurement takes place essentially simultaneously with the medical procedure.
摘要翻译：在用于监测医疗程序，特别是血管手术操作的监测方法和装置中，监测区域中的至少一个监测测量由医学成像装置获取，并且所述至少一个监测测量基本上与医学程序。

10. 发明申请

US20110125143A1 THERMAL ABLATION DEVICE, CATHETER AND METHOD TO IMPLEMENT A THERMAL ABLATION 审中-公开
标题翻译：热吸收装置，导管和实现热吸收的方法
公开(公告)号：US20110125143A1
公开(公告)日：2011-05-26
申请号：US12947357
申请日：2010-11-16
申请人： Patrick Gross , Clifford Weiss , Anke Weissenborn
发明人： Patrick Gross , Clifford Weiss , Anke Weissenborn
IPC分类号： A61B18/02 , A61B18/04
CPC分类号： A61N7/02 , A61B18/02 , A61B2017/00274 , A61B2018/00029 , A61B2018/00041 , A61B2018/0022 , A61B2018/00547 , A61B2018/0212
摘要： A thermal ablation device for introduction of heat or cold into the body of a patient has a first heating or cooling device to heat or cool the tissue to be ablated, as well as at least one additional cooling or heating arrangement that serves to cool or heat tissue surrounding the tissue to be ablated, and that can be introduced into a natural or latent cavity of the patient.
摘要翻译：用于将热或冷引入患者体内的热消融装置具有第一加热或冷却装置，用于加热或冷却要消融的组织，以及用于冷却或加热的至少一个额外的冷却或加热装置围绕要消融的组织的组织，并且可以将其引入患者的天然或潜在腔中。

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