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    • 1. 发明申请
    • Iceberg Reclamation Industry
    • 冰山填海工业
    • US20130071187A1
    • 2013-03-21
    • US13438439
    • 2012-04-03
    • Derek Andrew Lowe
    • Derek Andrew Lowe
    • E02B15/02
    • E02B15/02
    • Iceberg Reclamation industry invention provides an economical method of adapting offshore marine structures for arctic waters into fresh water production plants. The key condition of the invention is that icebergs are not towed or transported, instead the processing plant systematically breaks down icebergs and processes the ice pieces, melts the ice, and enables the transport of fresh water to arid climates and other areas in need of water reserves augmentation. The invention also claims that by decreasing the ice melt into oceans from icebergs this method acts as a sea level rise countermeasure. The method can also be used to clean oceans of floating debris and process the waste economically.
    • 冰山填海工业发明提供了一种经济的方法,将北极海域近海海洋结构适应淡水生产厂。 本发明的关键条件是冰山不被拖曳或运输,而是加工厂系统地分解冰山,处理冰块,融化冰块,使淡水运送到干旱气候和其他需要水的地方 储备增加。 本发明还声称,通过将冰融化物从冰山降低为海洋,该方法作为海平面升高对策。 该方法也可用于清理漂浮碎片的海洋,并经济地处理废物。
    • 2. 发明申请
    • Method and apparatus for determining cardiac medical parameters from supra-systolic
signals obtained from an oscillometric blood pressure system
    • 用于从超声心动图确定心脏医学参数的方法和装置
    • US20090312653A1
    • 2009-12-17
    • US12455516
    • 2009-06-03
    • Nigel E. SharrockAndrew Lowe
    • Nigel E. SharrockAndrew Lowe
    • A61B5/02
    • A61B5/022A61B5/02116A61B5/412
    • A method and apparatus are disclosed for determining certain cardiac medical parameters that are useful is diagnosing and treating cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of: (a) inflating a blood pressure cuff on the brachial artery to a supra-systolic pressure; (b) sensing a sequence of pressure pulse waveforms associated with the brachial artery that result from a plurality of cardiac ejection cycles; (c) averaging the waveforms to produce an average, representative waveform having an initial, incident wave portion and a reflected wave portion; (d) analyzing the representative waveform to determine a value of one or more cardiac medical parameters including the reflection wave ratio (RWR), the reflected wave transit time (RWTT), the maximum amplitude of the initial pressure wave (PS1), the maximum rise (slope) of the initial pressure wave (dp/dt), and/or the systolic ejection period (SEP); and (e) displaying the value of the medical parameter(s).
    • 公开了用于确定在诊断和治疗心血管疾病中有用的某些心脏医学参数的方法和装置。 该装置被设计为执行该方法,其包括以下步骤:(a)将肱动脉上的血压袖带膨胀至超收缩压; (b)感测由多个心脏射血周期产生的与肱动脉相关联的压力脉搏波形序列; (c)平均波形以产生具有初始入射波部分和反射波部分的平均代表性波形; (d)分析代表波形以确定一个或多个心脏医学参数的值,包括反射波比(RWR),反射波通过时间(RWTT),初始压力波(PS1)的最大振幅,最大值 初始压力波的上升(斜率)(dp / dt)和/或收缩期喷射周期(SEP); 和(e)显示医疗参数的值。
    • 3. 发明申请
    • Method for estimating a central pressure waveform obtained with a blood pressure cuff
    • 用于估计用血压袖带获得的中心压力波形的方法
    • US20090287097A1
    • 2009-11-19
    • US12454123
    • 2009-05-13
    • Andrew Lowe
    • Andrew Lowe
    • A61B5/02A61B5/0456
    • A61B5/022A61B5/02108A61B5/02225A61B5/411A61B5/6824A61B5/7239
    • A physics-based mathematical model is used to estimate central pressure waveforms from measurements of a brachial pressure waveform measured using a supra-systolic cuff. The method has been tested in numerous subjects undergoing cardiac catheterisation. Central pressure agreement was within 11 mm Hg and as good as the published non-invasive blood pressure agreement between the oscillometric device in use and the so-called “gold standard.” It also exceeds international standards for the performance of non-invasive blood pressure measurement devices. The method has a number of advantages including simplicity of application, fast calculation and accuracy of prediction. Additionally, model parameters have physical meaning and can therefore be tuned to individual subjects. Accurate estimation of central waveforms also allow continuous measurement (with intermittent calibration) using other non-invasive sensing systems including photoplethysmography.
    • 使用基于物理的数学模型来估计使用超声收缩袖带测量的肱动脉压波形的中心压力波形。 该方法已经在接受心脏导管插入术的许多受试者中进行了测试。 中央压力协议在11 mm Hg以内,与正在使用的示波器件与所谓“黄金标准”之间公布的无创血压协议一样好。 它也超过了非侵入性血压测量装置的性能的国际标准。 该方法具有应用简单,计算速度快,预测精度高等优点。 此外,模型参数具有物理意义,因此可以调整到个体科目。 准确估计中心波形还允许使用其他非侵入式感测系统(包括光电体积描记法)进行连续测量(间歇校准)。
    • 6. 发明申请
    • Preparation of transition metal nanoparticles and surfaces modified with (CO) polymers synthesized by RAFT
    • 制备用RAFT合成的(CO)聚合物改性的过渡金属纳米粒子和表面
    • US20070043179A1
    • 2007-02-22
    • US11586126
    • 2006-10-25
    • Charles McCormickAndrew LoweBrent Sumerlin
    • Charles McCormickAndrew LoweBrent Sumerlin
    • C08F4/00
    • B82Y30/00C01G5/00C01G7/00C01G55/00C01P2004/64C08F2/38C08F2/44C08F4/00C09C3/10Y10T428/31
    • A new, facile, general one-phase method of generating thiol-functionalized transition metal nanoparticles and surfaces modified by (co)polymers synthesized by the RAFT method is described. The method includes the steps of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a colloidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as functionalization with a variety of different chemical groups, expanding their utility and application.
    • 描述了通过RAFT方法合成的由(共)聚合物修饰的产生巯基官能化的过渡金属纳米颗粒和表面改性的新的,简单的通用单相方法。 该方法包括使用RAFT方法在水溶液中形成(共)聚合物的步骤,从合适的过渡金属形成胶态过渡金属前体溶液; 将金属前体溶液或表面添加到(共)聚合物溶液中,向溶液中加入还原剂以原位还原金属胶体以产生稳定的纳米颗粒或表面,并以这样的方式分离稳定的纳米颗粒或表面,使得聚集 被最小化。 使用这些方法产生的功能化表面可以进一步进行平面表面改性,例如用各种不同化学基团进行功能​​化,扩展它们的用途和应用。
    • 10. 发明申请
    • Blood pressure cuffs
    • 血压袖口
    • US20070203416A1
    • 2007-08-30
    • US11495279
    • 2006-07-28
    • Andrew Lowe
    • Andrew Lowe
    • A61B5/02
    • A61B5/02233A61B5/02208A61B2562/0261A61B2562/225A61B2562/227
    • A blood pressure cuff includes: (a) a flexible, hollow bladder adapted to surround the arm of the patient, which has an inside surface adapted to apply pressure to a surface of the arm above an artery, an outside surface opposite this inside surface, and an inlet line for receiving a fluid to cause the bladder to expand; (b) at least one first sensor element arranged on a inside and/or outside surface of the bladder in a location adjacent the artery when the bladder is in its operative position surrounding the patient's arm; and possibly also (c) at least one second sensor element arranged on a surface of the bladder that is opposite to the surface on which the first sensor element is disposed, and in a location adjacent the artery when the bladder is in its operative position surrounding the patient's arm. The sensor elements each comprise an elongate thin-film strip which transduces mechanical vibrations and produces an electrical signal representing these vibrations, normally in the range of 0 to 100 Hz.
    • 血压袖带包括:(a)适于包围患者臂的柔性中空囊,其具有内表面,该内表面适于对动脉上方的臂的表面施加压力,与该内表面相对的外表面, 以及用于接收流体以使膀胱膨胀的入口管线; (b)当膀胱处于其围绕患者的手臂的操作位置时,在与动脉相邻的位置中布置在囊的内侧和/或外表面上的至少一个第一传感器元件; 以及(c)至少一个第二传感器元件,其布置在与设置有第一传感器元件的表面相对的囊的表面上,并且当囊状物处于其动作位置时位于与动脉相邻的位置 病人的手臂。 传感器元件各自包括细长的薄膜条,其转换机械振动并产生表示这些振动的电信号,通常在0至100Hz的范围内。