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    • 1. 发明授权
    • Delay calibration for gamma camera timing circuit
    • 伽马相机定时电路的延迟校准
    • US6144034A
    • 2000-11-07
    • US120993
    • 1998-07-22
    • Thomas E. ScharfMichael J. Petrillo
    • Thomas E. ScharfMichael J. Petrillo
    • G01T1/164H03K5/00G01T1/166H03K5/22
    • G01T1/1647H03K2005/00097
    • A method and apparatus for calibrating a programmable delay in a timing circuit of a gamma camera detector are provided. The programmable delay has an error, the value of which is to be determined. An input signal that is applied as input to the programmable delay is simultaneously applied as input to a precision fixed delay. The fixed delay has a delay value within the programmable range of the programmable delay, but has an error that is substantially smaller than that of the programmable delay. The output of the programmable delay is applied to one input of a decision circuit, and the output of the fixed delay is applied to another input of the decision circuit. The delay of the programmable delay is initially programmed to a value that is substantially greater than the delay of the fixed delay, and input pulses are then applied to both delays. The delay value of the programmable delay is progressively decreased as input pulses are applied, until the output of the decision circuit indicates that the outputs of both delays are asserted concurrently. The error of the programmable delay is then computed based upon the programmed delay value. The programmable delay is then reprogrammed with a new delay value, based on the computed error, to achieve a desired delay value during normal operation of the timing circuit.
    • 提供了用于校准伽马相机检测器的定时电路中的可编程延迟的方法和装置。 可编程延迟有一个错误,其值将被确定。 作为可编程延迟的输入的输入信号同时作为精度固定延迟的输入。 固定延迟在可编程延迟的可编程范围内具有延迟值,但是具有明显小于可编程延迟的误差。 可编程延迟的输出被施加到判定电路的一个输入,并且固定延迟的输出被施加到判决电路的另一个输入端。 可编程延迟的延迟最初被编程为大大大于固定延迟的延迟的值,然后将输入脉冲施加到两个延迟。 当施加输入脉冲时,可编程延迟的延迟值逐渐减小,直到判决电路的输出指示两个延迟的输出同时被断言。 然后根据编程的延迟值计算可编程延迟的误差。 然后,基于计算出的误差,可编程延迟用新的延迟值进行重新编程,以在定时电路的正常操作期间实现期望的延迟值。
    • 2. 发明授权
    • Method and apparatus for performing correction of emission contamination
and deadtime loss in a medical imaging system
    • 用于执行医疗成像系统中的排放污染和死时间损失校正的方法和装置
    • US6008493A
    • 1999-12-28
    • US865930
    • 1997-05-30
    • Lingxiong ShaoHugo BertelsenPeter NellemanHorace Hines
    • Lingxiong ShaoHugo BertelsenPeter NellemanHorace Hines
    • G01T1/161G01T1/17G01T1/29G01T1/166
    • G01T1/1611G01T1/171G01T1/2985
    • A method of correcting for deadtime and for emission contamination of a transmission scan in a nuclear camera system is provided. The transmission scan is used to correct positron emission tomography (PET) images for attenuation. The camera system includes two detectors and two corresponding single-photon point sources that are collimated to produce fanbeam illumination profiles. A transmission detection window and an emission contamination detection window is defined on each detector. Radiation from each source is scanned axially across the field of view of the corresponding detector in synchronization with the corresponding transmission detection window to acquire transmission projection data. The emission contamination detection windows are also scanned axially concurrently with, but offset from, the transmission detection windows to acquire emission data. Events detected in the transmission detection windows are used to add counts from appropriate locations of the transmission projection on an event-by-event basis as those events are detected. Events detected in the emission contamination detection windows are used to subtract counts from appropriate locations of the transmission projection on an event-by-event basis as those events are detected. The number of counts by which a given location is incremented or decremented for each detected event is determined event-by-event from a look-up table based on the current singles rate.
    • 提供了一种校正核相机系统中的发射扫描的死区时间和发射污染的方法。 透射扫描用于校正正电子发射断层摄影(PET)图像以进行衰减。 相机系统包括两个检测器和两个对准的单光子点源,其被准直以产生扇形照明轮廓。 在每个检测器上定义传输检测窗口和排放污染检测窗口。 与对应的传输检测窗口同步地从相应检测器的视野轴向扫描来自每个源的辐射以获取传输投影数据。 排放污染检测窗口也与传输检测窗口轴向同时扫描但偏移以获取发射数据。 在发送检测窗口中检测到的事件用于在检测到事件时逐个事件的基础上从传输投影的适当位置添加计数。 在发射污染检测窗口中检测到的事件用于在检测到事件时逐个事件基础上从传输投影的适当位置减去计数。 基于当前单打率,从查找表中逐个事件确定给定位置对于每个检测到的事件递增或递减的计数次数。
    • 4. 发明授权
    • Tailored optical interface for scintillation camera detector
    • 用于闪烁相机检测器的定制光学接口
    • US5763887A
    • 1998-06-09
    • US691585
    • 1996-08-02
    • Matthew J. Murphy
    • Matthew J. Murphy
    • G01T1/164G01T1/20
    • G01T1/1642G01T1/2002A61B6/4258
    • A scintillation camera detector head comprises a scintillation crystal, a plurality of photomultiplier tubes (PMTs) optically coupled to the scintillation crystal, and a diffractive surface, such as a holographic optical element (HOE), optically coupled to the scintillation crystal. The diffractive surface preferentially reflects or redirects light from a scintillation event which impinges upon the surface toward one or more predetermined PMTs as a function of the angle of incidence or the location of the event. Light emitted under a peak PMT can be preferentially reflected or transmitted away from the peak PMT and toward the surrounding PMTs to reduce spatial resolution modulation. Alternatively, light impinging on the surface from an event can be directed toward the peak PMT and away from surrounding PMTs to achieve greater isolation of events.
    • 闪烁照相机检测器头包括闪烁晶体,与闪烁晶体光学耦合的多个光电倍增管(PMT)和光学耦合到闪烁晶体的衍射表面,例如全息光学元件(HOE)。 衍射表面优选地将来自闪烁事件的光反射或重定向,作为入射角或事件位置的函数的一个或多个预定PMT的冲击表面。 在峰值PMT下发射的光可以优先反射或远离峰值PMT并朝着周围的PMT发射以减少空间分辨率调制。 或者,从事件撞击在表面上的光可以被引导到峰值PMT并远离周围的PMT以实现更大的事件隔离。
    • 5. 发明授权
    • Scan speed for transmission exposure reduction in a nuclear medicine
camera
    • 用于核医学相机的传输曝光减少的扫描速度
    • US5629971A
    • 1997-05-13
    • US439111
    • 1995-05-11
    • Steven M. JonesMichael J. JanickiThomas F. LangJohn R. LiebigXiaohan Wang
    • Steven M. JonesMichael J. JanickiThomas F. LangJohn R. LiebigXiaohan Wang
    • G01T1/164G21K5/10
    • G01T1/1615A61B6/037G01T1/1611G01T1/1642
    • A scan speed procedure and method wherein a minimum radiation exposure period is determined on an object by object basis for a transmission study. Two transmission scans are performed including a prescan followed by a second transmission scan phase. The first transmission prescan is performed using a radiation source over the object. This prescan is of a rapid and predetermined duration (Tp). A resultant count density associated with the object is then generated and examined. The portion having the smallest count density (Cm) is determined and a value (Co) representing the minimum required number of counts for transmission study is given. From the above, a transmission period (Ts) is determined by the system and the second transmission scan phase is performed for the duration Ts using a multi-pass scan phase. The computed duration Ts represents the minimum exposure duration required to collect transmission data to ensure that the count density distribution associated with the object will contain at least Cm count density over each portion of the object.
    • 一种扫描速度程序和方法,其中针对传输研究,逐对象地确定最小辐射暴露周期。 执行两次传输扫描,包括预扫描,随后是第二传输扫描阶段。 使用物体上的辐射源执行第一传输预扫描。 该预扫描具有快速和预定的持续时间(Tp)。 然后生成并检查与对象相关联的合成计数密度。 确定具有最小计数密度(Cm)的部分,并且给出表示用于传输研究的最小所需计数数量的值(Co)。 从上述可以看出,系统确定了传输周期(Ts),并且使用多遍扫描阶段对持续时间Ts执行第二传输扫描阶段。 所计算的持续时间Ts表示收集传输数据所需的最小曝光持续时间,以确保与对象相关联的计数密度分布在对象的每个部分上至少包含Cm计数密度。
    • 6. 发明授权
    • Large field of view transmission and small field of view emission scan
within gamma camera system
    • 伽马相机系统中的大视野传输和小视野发射扫描
    • US5598003A
    • 1997-01-28
    • US438834
    • 1995-05-11
    • Steven M. JonesMichael J. JanickiThomas F. LangJ. Keenan BrownJohn R. LiebigXiaohan Wang
    • Steven M. JonesMichael J. JanickiThomas F. LangJ. Keenan BrownJohn R. LiebigXiaohan Wang
    • G01T1/164G01T1/161
    • G01T1/1648A61B6/037G01T1/1642
    • A method and apparatus for collecting transmission information utilizing a large field of view of a detector and for collecting emission data using a small field of view window of the same detector. The system employs the large field of view of a scintillation detector in order to collect transmission data for the entire body being scanned. Such a technique improves the quantitative capability of emission data by acquiring non-truncated attenuation factors. The emission data of a small field of view window is collected so that high resolution image pixels are used for processing the emission data (e.g., of a particular body organ). Since a large field of view is used for collecting the transmission data, the imaging pixels for transmission data are of lower resolution than the emission data. The emission data can be collected using a roving zoom technique during an ECT scan. A computation adjusts the transmission data to account for the known location of the emission zoom window on the crystal and for the different pixel sizes between the full field of view transmission scan of the body and the smaller roving electronic field of view emission scan of the body organ.
    • 一种用于利用检测器的大视野来收集传输信息并且使用相同检测器的小视野窗收集发射数据的方法和装置。 该系统采用闪烁检测器的大视野,以便收集被扫描的整个身体的传输数据。 这种技术通过获取非截断衰减因子来提高发射数据的定量能力。 收集小视场窗口的发射数据,使得高分辨率图像像素用于处理发射数据(例如,特定身体器官)。 由于使用大的视野来收集传输数据,所以用于传输数据的成像像素的分辨率低于发射数据。 在ECT扫描期间,可以使用粗纱放大技术收集排放数据。 计算调整传输数据以考虑在晶体上的发射变焦窗口的已知位置以及身体的全视野透射扫描与身体的较小的粗纱电子视野发射扫描之间的不同像素尺寸 器官。
    • 7. 发明授权
    • Modifiable digital dynamic compression table
    • 可修改数字动态压缩表
    • US5539202A
    • 1996-07-23
    • US317931
    • 1994-10-03
    • Michael GeaganDonald R. Wellnitz
    • Michael GeaganDonald R. Wellnitz
    • G01T1/164G01T1/17G01T1/208G01T1/20
    • G01T1/17G01T1/1647G01T1/208
    • A circuit for performing digital dynamic compression wherein the circuit is readily modifiable to accept different compression procedures and the input and output signals are in digital form. The system utilizes a memory unit (e.g., a random access memory or other form of programmable memory, such as EEPROM) to contain a procedure utilized to transform digital input channel signal to an offset digital value which is determined based on the total energy of a gamma interaction. This offset digital value is then subtracted from the digital input channel data to arrive at the output dynamically compressed value. However, given sufficient memory size, the memory circuit may be implemented to directly output the compressed value. Since a programmable memory look up table is utilized to contain the dynamic compression procedure, different dynamic compression procedures may be readily loaded into the memory from a computer system. The compression procedure is implemented such that there are no nonuniformities near the signal range transitions.
    • 一种用于执行数字动态压缩的电路,其中电路易于修改以接受不同的压缩过程,并且输入和输出信号是数字形式。 该系统利用存储器单元(例如,随机存取存储器或其他形式的可编程存储器,例如EEPROM)来包含用于将数字输入通道信号转换为基于一个的总能量确定的偏移数字值的过程 伽马相互作用。 然后从数字输入通道数据中减去该偏移数字值,得到输出动态压缩值。 然而,给定足够的存储器大小,可以实现存储器电路以直接输出压缩值。 由于使用可编程存储器查找表来包含动态压缩过程,因此可以从计算机系统容易地将不同的动态压缩过程加载到存储器中。 压缩过程被实现为使得在信号范围转换附近没有不均匀性。
    • 9. 发明授权
    • Method and apparatus for performing correction of transmission
self-contamination in a medical imaging system
    • 用于执行医疗成像系统中的传输自身污染的校正的方法和装置
    • US5990482A
    • 1999-11-23
    • US865918
    • 1997-05-30
    • Hugo BertelsenLingxiong Shao
    • Hugo BertelsenLingxiong Shao
    • G01T1/164G01T1/166
    • G01T1/1648
    • A method of acquiring transmission self-contamination data for correcting transmission scan data in a nuclear camera system including two transmission radiation sources and two scintillation detectors. A first source is for transmitting radiation to only a first detector and a second source is for transmitting radiation to only a second detector during a transmission scan of an object to be imaged. To acquire the calibration data, radiation is transmitted from the second source to the second detector while the first source is maintained in a non-transmitting state. While the second source is transmitting, the first detector is used to detect the radiation transmitted from the second source. A set of self-contamination data is then generated based on the radiation from the second source detected with the first detector. The calibration data is used to correct a subsequent transmission scan of the object by subtracting the self-contamination data from the transmission scan data.
    • 一种获取用于校正包括两个发射辐射源和两个闪烁检测器的核相机系统中的传输扫描数据的传输自身污染数据的方法。 第一来源是用于将辐射传输到仅第一检测器,并且第二源用于在待成像对象的透射扫描期间仅向第二检测器发射辐射。 为了获取校准数据,辐射从第二源发送到第二检测器,同时第一源保持在非发射状态。 当第二个信号源正在传输时,第一个检测器用于检测从第二个信号源发射的辐射。 然后基于用第一检测器检测到的来自第二源的辐射产生一组自污染数据。 校准数据用于通过从传输扫描数据中减去自身污染数据来校正对象的后续传输扫描。
    • 10. 发明授权
    • Dual-mode gamma camera system utilizing single-photon transmission
scanning for attenuation correction of PET data
    • 双模γ相机系统利用单光子传输扫描对PET数据进行衰减校正
    • US5900636A
    • 1999-05-04
    • US865916
    • 1997-05-30
    • Peter NellemannHugo BertelsenLingxiong ShaoHorace H. Hines
    • Peter NellemannHugo BertelsenLingxiong ShaoHorace H. Hines
    • G01T1/161G01T1/164G01T1/29G21K5/10
    • G01T1/1611A61B6/037G01T1/1642G01T1/1648
    • A nuclear camera system includes a pair of detectors orientated 180 degrees apart about an axis of rotation for detecting radiation emitted from an object, a pair of single-photon radiation point sources for transmitting radiation through the object, each to a different detector, and a gantry supporting the detectors and the radiation sources. The gantry provides rotation of the detectors and the radiation source about the axis of rotation, such that the angular positions of the radiation source about the axis of rotation remain fixed relative to the angular positions of the detectors. The camera system further includes a processing system coupled to control the dectors and the radiation sources and to selectably configure the detectors for either coincidence or single-photon emission imaging. The processing system controls the detectors to acquire coincidence emission data of the object and controls the single-photon point sources to acquire transmission data of the object, wherein the radiation from the point sources has a fanbeam illumination profile. The processing system corrects the acquired coincidence emission data for attenuation using the transmission data.
    • 核相机系统包括一对围绕旋转轴定向180度的检测器,用于检测从物体发射的辐射;一对单光子辐射点源,用于将辐射通过物体传送到不同的检测器;以及 龙门架支持探测器和辐射源。 台架提供检测器和辐射源围绕旋转轴的旋转,使得辐射源围绕旋转轴线的角位置相对于检测器的角位置保持固定。 相机系统还包括耦合以控制分界器和辐射源的处理系统,并且可选地配置用于重合或单光子发射成像的检测器。 处理系统控制检测器以获取对象的重合发射数据,并控制单光点点源以获取对象的传输数据,其中来自点源的辐射具有扇形照明轮廓。 处理系统使用传输数据来校正获得的用于衰减的重合发射数据。