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    • 1. 发明授权
    • Large field of view transmission and small field of view emission scan
within gamma camera system
    • 伽马相机系统中的大视野传输和小视野发射扫描
    • US5598003A
    • 1997-01-28
    • US438834
    • 1995-05-11
    • Steven M. JonesMichael J. JanickiThomas F. LangJ. Keenan BrownJohn R. LiebigXiaohan Wang
    • Steven M. JonesMichael J. JanickiThomas F. LangJ. Keenan BrownJohn R. LiebigXiaohan Wang
    • G01T1/164G01T1/161
    • G01T1/1648A61B6/037G01T1/1642
    • A method and apparatus for collecting transmission information utilizing a large field of view of a detector and for collecting emission data using a small field of view window of the same detector. The system employs the large field of view of a scintillation detector in order to collect transmission data for the entire body being scanned. Such a technique improves the quantitative capability of emission data by acquiring non-truncated attenuation factors. The emission data of a small field of view window is collected so that high resolution image pixels are used for processing the emission data (e.g., of a particular body organ). Since a large field of view is used for collecting the transmission data, the imaging pixels for transmission data are of lower resolution than the emission data. The emission data can be collected using a roving zoom technique during an ECT scan. A computation adjusts the transmission data to account for the known location of the emission zoom window on the crystal and for the different pixel sizes between the full field of view transmission scan of the body and the smaller roving electronic field of view emission scan of the body organ.
    • 一种用于利用检测器的大视野来收集传输信息并且使用相同检测器的小视野窗收集发射数据的方法和装置。 该系统采用闪烁检测器的大视野,以便收集被扫描的整个身体的传输数据。 这种技术通过获取非截断衰减因子来提高发射数据的定量能力。 收集小视场窗口的发射数据,使得高分辨率图像像素用于处理发射数据(例如,特定身体器官)。 由于使用大的视野来收集传输数据,所以用于传输数据的成像像素的分辨率低于发射数据。 在ECT扫描期间,可以使用粗纱放大技术收集排放数据。 计算调整传输数据以考虑在晶体上的发射变焦窗口的已知位置以及身体的全视野透射扫描与身体的较小的粗纱电子视野发射扫描之间的不同像素尺寸 器官。
    • 2. 发明授权
    • Scan speed for transmission exposure reduction in a nuclear medicine
camera
    • 用于核医学相机的传输曝光减少的扫描速度
    • US5629971A
    • 1997-05-13
    • US439111
    • 1995-05-11
    • Steven M. JonesMichael J. JanickiThomas F. LangJohn R. LiebigXiaohan Wang
    • Steven M. JonesMichael J. JanickiThomas F. LangJohn R. LiebigXiaohan Wang
    • G01T1/164G21K5/10
    • G01T1/1615A61B6/037G01T1/1611G01T1/1642
    • A scan speed procedure and method wherein a minimum radiation exposure period is determined on an object by object basis for a transmission study. Two transmission scans are performed including a prescan followed by a second transmission scan phase. The first transmission prescan is performed using a radiation source over the object. This prescan is of a rapid and predetermined duration (Tp). A resultant count density associated with the object is then generated and examined. The portion having the smallest count density (Cm) is determined and a value (Co) representing the minimum required number of counts for transmission study is given. From the above, a transmission period (Ts) is determined by the system and the second transmission scan phase is performed for the duration Ts using a multi-pass scan phase. The computed duration Ts represents the minimum exposure duration required to collect transmission data to ensure that the count density distribution associated with the object will contain at least Cm count density over each portion of the object.
    • 一种扫描速度程序和方法,其中针对传输研究,逐对象地确定最小辐射暴露周期。 执行两次传输扫描,包括预扫描,随后是第二传输扫描阶段。 使用物体上的辐射源执行第一传输预扫描。 该预扫描具有快速和预定的持续时间(Tp)。 然后生成并检查与对象相关联的合成计数密度。 确定具有最小计数密度(Cm)的部分,并且给出表示用于传输研究的最小所需计数数量的值(Co)。 从上述可以看出,系统确定了传输周期(Ts),并且使用多遍扫描阶段对持续时间Ts执行第二传输扫描阶段。 所计算的持续时间Ts表示收集传输数据所需的最小曝光持续时间,以确保与对象相关联的计数密度分布在对象的每个部分上至少包含Cm计数密度。
    • 3. 发明授权
    • Variable filters used with radiation source to reduce unobstructed
detector area
    • 与辐射源一起使用的可变滤波器,以减少无障碍的检测器面积
    • US5552606A
    • 1996-09-03
    • US439134
    • 1995-05-11
    • Steven M. JonesMichael J. JanickiThomas E. LangJohn R. LiebigXiaohan Wang
    • Steven M. JonesMichael J. JanickiThomas E. LangJohn R. LiebigXiaohan Wang
    • G01T1/161G01T1/164G01T1/00
    • G01T1/1615A61B6/037G01T1/1611G01T1/1642G01T1/1648
    • A variable filter arrangement wherein differently sized and shaped filters are automatically selected and installed from a collection of filters housed within a configuration for use with a radiation source. The line source is typically used for transmission scanning to collect attenuation correction factors. A line source is utilized in the preferred embodiment and a series of filters (e.g., differently sized "bow-tie" filters) are rotatably attached to a central junction so that a particular filter can be rotated into an installed position. When installed, the filter acts to attenuate the radiation emitted from the line source to reduce radiation emitted on an otherwise unobstructed area of a scintillation detector. Differently sized filters are advantageously used to accommodate differently sized patents and also to accommodate different unobstructed parts of a detector for different angles of rotation during an ECT transmission scan. The system includes processing intelligence to automatically select the proper filter given body contour (e.g., profile) information.
    • 可变过滤器装置,其中不同尺寸和形状的过滤器被自动选择并从容纳在用于辐射源的配置内的过滤器的集合中安装。 线源通常用于传输扫描以收集衰减校正因子。 在优选实施例中使用线源,并且一系列过滤器(例如,不同尺寸的“蝴蝶结”过滤器)可旋转地附接到中心连接点,使得特定的过滤器可以旋转到安装位置。 当安装时,滤波器用于衰减从线源发射的辐射,以减少在闪烁检测器的其他无阻挡区域上发射的辐射。 不同大小的过滤器有利地用于适应不同大小的专利,并且还可以在ECT传输扫描期间适应不同旋转角度的检测器的不同的不阻碍部分。 该系统包括处理智能以自动选择给定身体轮廓(例如,轮廓)信息的适当的过滤器。
    • 4. 发明授权
    • Use of body boundary information to perform iterative reconstruction in
medical imaging system
    • 使用身体边界信息在医学成像系统中进行迭代重建
    • US5739539A
    • 1998-04-14
    • US625533
    • 1996-03-27
    • Xiaohan WangJ. Keenan BrownSteven M. JonesJohn R. Liebig
    • Xiaohan WangJ. Keenan BrownSteven M. JonesJohn R. Liebig
    • G01T1/164G01T1/166G01T1/29
    • G06T11/003A61B6/4258G01T1/1611G01T1/1615G01T1/1642G01T1/1648G01T1/166G01T1/2985
    • A method of performing image reconstruction in a gamma camera system comprises the steps of performing a transmission scan of an object about a number of rotation angles to collect transmission projection data and performing an emission scan of the object about numerous rotation angles to collect emission projection data. The outer boundary of the object is then located based on the transmission projection data. Information identifying the boundary is then either stored in a separate body contour map or embedded in an attenuation map. The information identifying the boundary can be in the form of flags indicating whether individual pixels are inside or outside the boundary of the object. The emission projection data is then reconstructed, using the attenuation map if desired, to generate transverse slice images. By using the body boundary information, portions of the emission projection data representing points outside the boundary of the object are not reconstructed in order to reduce total reconstruction time.
    • 在伽马照相机系统中执行图像重建的方法包括以下步骤:对多个旋转角度进行物体的发射扫描,以收集透射投影数据,并执行关于多个旋转角度的物体的发射扫描以收集发射投影数据 。 然后基于传输投影数据来定位对象的外边界。 然后将识别边界的信息存储在单独的身体轮廓图中或嵌入衰减图中。 识别边界的信息可以是指示个体像素是否在对象的边界内部或外部的标志的形式。 然后如果需要,使用衰减图重建发射投影数据,以产生横切片图像。 通过使用身体边界信息,不重建表示物体边界外的点的发射投影数据的部分,以减少总重构时间。
    • 5. 发明授权
    • Dual synchronized sliding transmission detection windows for dual
transmission line sources
    • 用于双路传输线路源的双同步滑动传输检测窗口
    • US5596197A
    • 1997-01-21
    • US439222
    • 1995-05-11
    • Steven M. JonesThomas F. LangJohn R. LiebigXiaohan Wang
    • Steven M. JonesThomas F. LangJohn R. LiebigXiaohan Wang
    • G01T1/164G01T1/161
    • G01T1/1615A61B6/037G01T1/1611G01T1/1642G01T1/1648
    • A mechanism and method for performing transmission and emission scanning sessions with two line sources and two detectors wherein two sliding transmission detection windows are employed to differentiate between transmission and emission photons. Transmission and emission data can be collected simultaneously. This system provides that the dual transmission detection windows are each associated with a particular line source and move in synchronization with the associated line source. Further, the two line sources and the two detector windows all move in synchronization in the direction of the long axis of the object being scanned and at any given position all are within a given spatial plane that is transverse to the long axis of the object. In this configuration, the system can effectively reduce the amount of cross-talk detected by a detector (e.g., cross-talk being scattered photon radiation detected by a given detector but not originating from the detector's associated line source). The configuration of this system also effectively operates in conjunction with systems employing tracking zoom regions across detector surfaces (e.g., used for cardiac studies).
    • 用于利用两个线路源和两个检测器执行发射和发射扫描会话的机构和方法,其中采用两个滑动传输检测窗口来区分传输和发射光子。 传输和排放数据可以同时收集。 该系统提供双传输检测窗口各自与特定的线路源相关联并且与相关联的线路源同步地移动。 此外,两条线源和两个检测器窗口都沿被扫描物体的长轴方向同步移动,并且在任何给定位置都在与物体的长轴横切的给定空间平面内。 在该配置中,系统可以有效地减少由检测器检测到的串扰量(例如,串扰是由给定检测器检测到但不是源于检测器的相关线路源的散射光子辐射)。 该系统的配置还与跨越检测器表面的跟踪缩放区域(例如,用于心脏研究)的系统结合有效地操作。
    • 6. 发明授权
    • Coregistration of multi-modality data in a medical imaging system
    • 医学成像系统中多模态数据的核心
    • US5672877A
    • 1997-09-30
    • US623908
    • 1996-03-27
    • John R. LiebigSteven M. JonesXiaohan Wang
    • John R. LiebigSteven M. JonesXiaohan Wang
    • G01T1/161G01T1/164G01T1/166
    • G01T1/1648A61B6/037A61B6/5235A61B6/5247
    • A method of coregistering medical image data of different modalities is provided. In the method, an emission scan of an object is performed using a nuclear medicine imaging system to acquire single-photon emission computed tomography (SPECT) image data. A transmission scan of the object is performed simultaneously with the emission scan using the same nuclear medicine imaging system in order to acquire nuclear medicine transmission image data. The emission scan is performed using a roving zoom window, while the transmission scan is performed using the full field of view of the detectors. By knowing the position of the zoom windows for each detection angle, the nuclear medicine transmission image data can be coregistered with the SPECT emission image data as a result of the simultaneous scans. Image data of a modality other than SPECT, such as x-ray computed tomography (x-ray CT) data, magnetic resonance imaging (MRI) data, or positron emission tomography (PET) data, is also provided, which it is desired to have coregistered with the SPECT emission data. The nuclear medicine transmission image data is therefore coregistered with the image data of the different modality. As a result, the image data of the different modality becomes coregistered with the SPECT image data.
    • 提供了一种使不同形式的医学图像数据结合的方法。 在该方法中,使用核医学成像系统进行物体的发射扫描,以获取单光子发射计算机断层摄影(SPECT)图像数据。 与使用相同的核医学成像系统的发射扫描同时进行物体的透射扫描,以获得核医学传播图像数据。 使用粗纱缩放窗口进行发射扫描,而使用检测器的全视场执行透射扫描。 通过了解每个检测角度的变焦窗口的位置,作为同时扫描的结果,核医学传播图像数据可以与SPECT发射图像数据结合。 还提供了诸如x射线计算机断层摄影(x射线CT)数据,磁共振成像(MRI)数据或正电子发射断层摄影(PET)数据之外的SPECT之外的模式的图像数据,期望 与SPECT排放数据有核心关系。 因此,核医学传播图像数据与不同形式的图像数据结合在一起。 结果,不同模态的图像数据变得与SPECT图像数据成为核心。
    • 8. 发明授权
    • Spectroscopic ellipsometers
    • 光谱椭圆仪
    • US07999949B2
    • 2011-08-16
    • US11739679
    • 2007-04-24
    • Tongxin LuXiaohan Wang
    • Tongxin LuXiaohan Wang
    • G01B11/30
    • G01N21/211G01B11/0625G01N21/9501G01N2021/213G01N2021/8427G01N2201/0636G01N2201/0637
    • The present invention discloses an optical measurement and/or inspection device that, in one application, may be used for inspection of semiconductor devices. A method is disclosed for extracting information of a device-under-test for an ellipsometer, comprising the steps: providing a plurality of incoming polarized beams using a plurality of polarizers, where each of the beams being polarized at a designated polarizing angle; using a parabolic reflector to focus said plurality of incoming polarized beams on a spot on a DUT; using a parabolic reflector to collect a plurality of beams reflected from said DUT; and analyzing said collected beams using a plurality of analyzers, wherein each of the analyzers having a designated polarizing angle with respect to its respective polarizer.
    • 本发明公开了一种光学测量和/或检查装置,其在一个应用中可用于半导体器件的检查。 公开了一种用于提取椭偏仪的未测试装置的信息的方法,包括以下步骤:使用多个偏振器提供多个入射偏振光束,其中每个光束以指定的偏振角极化; 使用抛物面反射器将所述多个入射偏振光束聚焦在DUT上的点上; 使用抛物面反射器收集从所述DUT反射的多个光束; 以及使用多个分析器分析所述收集的束,其中每个分析器相对于其各自的偏振器具有指定的偏振角。
    • 10. 发明授权
    • Correction for Compton scattering by analysis of energy spectra
    • 通过分析能谱校正康普顿散射
    • US5081581A
    • 1992-01-14
    • US331993
    • 1989-03-31
    • Kenneth F. KoralW. Leslie RogersNeal H. ClinthorneXiaohan Wang
    • Kenneth F. KoralW. Leslie RogersNeal H. ClinthorneXiaohan Wang
    • G01T1/164G06T11/00
    • G06T11/005G01T1/1647
    • A system for removing the effects of Compton scattering in systems such as tomographic scanning and radioisotope imaging arrangements, which detect gamma rays, utilizes the smoothness of the Compton component over the image to reduce computing time. Data responsive to energy states of the photons which are detected are received and values corresponding thereto are stored in at least one memory location. In some embodiments, where imaging is the ultimate function of the gamma ray detection system, the data correspond to predetermined image grid points. Also, the data which is stored is processed so as to be separated into a first data set corresponding to unscattered ones of the detected photons and a second data set corresponding to scattered ones of the detected photons. The gamma ray detection arrangement is calibrated by acquiring a spectral shape corresponding to unscattered photons. The processing utilizes non-linear least squares fitting analysis. The first data set is summed within specified limits, for determining a number of the unscattered ones of the detected photons. A scatter-free image can then be formed from this data set.
    • 用于消除科普顿散射在诸如层析扫描和放射性同位素成像布置的系统中的影响的系统,其检测伽马射线,利用Compton分量在图像上的平滑度来减少计算时间。 接收响应于检测到的光子的能量状态的数据,并且对应于其的值被存储在至少一个存储器位置中。 在一些实施例中,其中成像是伽马射线检测系统的最终功能,数据对应于预定的图像网格点。 而且,对存储的数据进行处理,以被分离成对应于未被分散的检测到的光子的第一数据集和对应于所检测到的光子的散射的第二数据集。 通过获取对应于未散射光子的光谱形状来校准伽马射线检测装置。 该处理采用非线性最小二乘拟合分析。 第一数据集合在指定限度内,用于确定检测到的光子中未散射的光子的数量。 然后可以从该数据集形成无散射图像。