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1. 发明授权

US5508524A Spatially variant PMT cluster constitution and spatially variant PMT weights 失效
标题翻译：空间变异的PMT簇结构和空间变异的PMT重量
公开(公告)号：US5508524A
公开(公告)日：1996-04-16
申请号：US317553
申请日：1994-10-03
申请人： Edward M. Goldberg , Gerd Muehllehner , Matthew J. Murphy , Donald R. Wellnitz
发明人： Edward M. Goldberg , Gerd Muehllehner , Matthew J. Murphy , Donald R. Wellnitz
IPC分类号： G01T1/164 , G01T1/17 , G01T1/208 , G01T1/20
CPC分类号： G01T1/17 , G01T1/1647 , G01T1/208
摘要： A system including circuitry within a gamma camera system for generating spatially variant photomultiplier cluster based on a peak photomultiplier and for generating spatially variant weights for photomultipliers of the cluster depending on a cluster type signal. The system includes a first memory circuit addressed by a peak photomultiplier address signal and responsive thereto which generates (1) a unique photomultiplier cluster in geometry and size for the peak photomultiplier and (2) a cluster type. A resolution input signal (high/low) changes the size of the cluster. The first memory is programmable. A second memory responsive to photomultiplier addresses of the cluster and the cluster type, generates weight values for each photomultiplier. The second memory is programmable. The second memory allows weights for individual photomultipliers to be altered based on the geometry and size (e.g., type) of the cluster generated by the first memory. The system can effectively operate within a digital gamma camera system.
摘要翻译：一种包括伽马照相机系统内的电路的系统，用于基于峰值光电倍增管生成空间变化的光电倍增管簇，并根据簇类型信号产生簇的光电倍增管的空间变异权重。该系统包括由峰值光电倍增器地址信号寻址并响应于此的第一存储器电路，其产生（1）用于峰值光电倍增管的几何形状和尺寸的唯一光电倍增管簇，以及（2）簇类型。分辨率输入信号（高/低）会改变群集的大小。第一个存储器是可编程的。响应于集群的光电倍增器地址和集群类型的第二个存储器为每个光电倍增管产生重量值。第二个存储器是可编程的。第二存储器允许基于由第一存储器生成的簇的几何形状和大小（例如，类型）来改变各个光电倍增管的权重。该系统可以在数字伽马相机系统内有效的操作。

2. 发明申请

US20100292628A1 Pressure Monitoring within a Fluid Cassette 有权
标题翻译：流体盒内的压力监测
公开(公告)号：US20100292628A1
公开(公告)日：2010-11-18
申请号：US12465327
申请日：2009-05-13
申请人： Edward T. Powers , Matthew J. Murphy , Michael Ragusa
发明人： Edward T. Powers , Matthew J. Murphy , Michael Ragusa
IPC分类号： A61M1/36 , A61M37/00 , G01L7/00
CPC分类号： A61M1/3639 , A61M1/3472 , A61M2205/12 , A61M2205/3331 , A61M2205/7518 , A61M2205/7536
摘要： A fluid cassette for a blood processing system includes a cassette housing and a rigid structure. The cassette housing defines the structure of the cassette and has a fluid path at least partially extending through it. The fluid path is configured to allow a fluid to pass through the housing. The rigid structure defines a cavity that is in fluid communication with the fluid path. The rigid structure also has an interface for interfacing and/or connecting with a pressure monitoring device. The interface allows the pressure monitoring device to measure the pressure within the fluid path. The cavity has a volume of air located between the fluid path and the interface.
摘要翻译：用于血液处理系统的流体盒包括盒壳体和刚性结构。盒壳体限定了盒的结构，并且具有至少部分延伸通过其的流体路径。流体路径被配置为允许流体通过壳体。刚性结构限定了与流体路径流体连通的空腔。刚性结构还具有用于与压力监测装置进行接口和/或连接的接口。该界面允许压力监测装置测量流体路径内的压力。空腔具有位于流体路径和界面之间的空气体积。

3. 发明授权

US07238165B2 Fluid pump 有权
标题翻译：流体泵
公开(公告)号：US07238165B2
公开(公告)日：2007-07-03
申请号：US10372023
申请日：2003-02-21
申请人： Douglas Vincent , Matthew J. Murphy
发明人： Douglas Vincent , Matthew J. Murphy
IPC分类号： A61M37/00 , A61M1/10 , A61M1/00 , A61M31/00 , A61N1/362
CPC分类号： A61M1/1053 , A61M1/10 , A61M1/1005 , A61M1/1037 , A61M1/1055 , A61M1/1062 , A61M1/1086 , A61M1/1096 , A61M1/122 , A61M2230/04 , A61M2230/005
摘要： A pumping system 10 provides a physiological pulsatile flow and includes controller 121, a pump drive head 50 coupled to a motor 12 and a fluid housing 52 having at least one port 60. The port 60 includes a ball valve retainer region 69, a valve seat 73, and an occluder ball 71 disposed in the ball valve retainer region 69. During operation, the motor 12 forces the fluid in and out the fluid housing 52 and causes the occluder ball 71 to move from a first position whereby the fluid cannot pass through the port 60, to a second position whereby the fluid moves annular to and generally around the occluder ball 71. This movement creates a slight flow reversal that “breaks up” any blood clots that may form. The pumping system may be used as part of a cardiopulmonary bypass system, a ventricular assist device (VAD) and/or a heart pump.
摘要翻译：泵送系统10提供生理脉动流，并且包括控制器121，联接到马达12的泵驱动头50和具有至少一个端口60的流体壳体52。端口60包括设置在球阀保持器区域69中的球阀保持器区域69，阀座73和闭塞球71。在操作期间，马达12迫使流体进入和流出流体壳体52，并且使堵塞球71从第一位置移动，由此流体不能通过端口60到达第二位置，由此流体环形移动并且通常围绕封堵器球71。这种运动产生轻微的逆转，“分解”可能形成的任何血块。泵送系统可以用作体外循环系统，心室辅助装置（VAD）和/或心脏泵的一部分。

4. 发明授权

US5602395A Gamma camera having partial septas and moving septas for positron emission tomography (PET) 失效
标题翻译：具有部分隔膜的伽玛相机和用于正电子发射断层摄影（PET）的移动隔垫
公开(公告)号：US5602395A
公开(公告)日：1997-02-11
申请号：US537008
申请日：1995-10-02
申请人： Peter Nellemann , Horace H. Hines , Gerd Muehllehner , Matthew J. Murphy
发明人： Peter Nellemann , Horace H. Hines , Gerd Muehllehner , Matthew J. Murphy
IPC分类号： G01T1/164 , G01T1/166
CPC分类号： G01T1/1648 , A61B6/037 , G01T1/1642
摘要： A gamma camera for a Positron Emission Tomography (PET) system comprises a single, continvous scintillation crystal having an imaging surface, and a first layer of septa disposed along the imaging surface between the object and the imaging surface. A gap is provided between the imaging surface and the first layer of septa to allow non stray radiation to reach the imaging surface. The septa may be arranged to have a long axis disposed at an acute angle away from perpendicular to an axis of rotation or made to move in relation to the imaging surface of the scintillation crystal to reduce cold spots on the image. Multiple layers of septa may be provided.
摘要翻译：用于正电子发射断层扫描（PET）系统的γ照相机包括具有成像表面的单个连续闪烁晶体和沿物体和成像表面之间的成像表面设置的第一隔离层。在成像表面和第一隔膜层之间提供间隙以允许非杂散辐射到达成像表面。隔垫可以被布置成具有远离垂直于旋转轴线的锐角设置的长轴，或者相对于闪烁晶体的成像表面移动以减少图像上的冷点。可以提供多层隔膜。

5. 发明授权

US5299824A Wheel chair with rotatable tray 失效
标题翻译：带旋转托盘的轮椅
公开(公告)号：US5299824A
公开(公告)日：1994-04-05
申请号：US964100
申请日：1992-10-21
申请人： Richard D. Roberts , Matthew J. Murphy
发明人： Richard D. Roberts , Matthew J. Murphy
IPC分类号： A61G5/10 , B60R9/00
CPC分类号： A61G5/10 , A61G5/1054 , A61G5/1094 , A47B2200/0031 , Y10S297/04
摘要： A wheel chair with a rotating tray which may be rotated from a first position generally parallel to a back or rear support member. In an alternative position of the rotating tray, the tray is rotated from the first position generally parallel to the arm supports through ninety degrees into a vertical position whereby the user of the wheel chair is able to get up from and return to a bottom seat of the wheel chair.
摘要翻译：具有旋转托盘的轮椅，其可以从大体上平行于后部或后部支撑构件的第一位置旋转。在旋转托盘的替代位置，托盘从大体上平行于臂支撑件的第一位置旋转90度到垂直位置，由此轮椅的使用者能够起床并返回到底座轮椅。

6. 发明授权

US07850593B2 Fluid pump 有权
标题翻译：流体泵
公开(公告)号：US07850593B2
公开(公告)日：2010-12-14
申请号：US11751954
申请日：2007-05-22
申请人： Douglas Vincent , Matthew J. Murphy
发明人： Douglas Vincent , Matthew J. Murphy
IPC分类号： A61N1/362
CPC分类号： A61M1/1053 , A61M1/10 , A61M1/1005 , A61M1/1037 , A61M1/1055 , A61M1/1062 , A61M1/1086 , A61M1/1096 , A61M1/122 , A61M2230/04 , A61M2230/005
摘要： A pumping system 10, FIG. 1, provides a physiological pulsatile flow and includes controller 121, a pump drive head 50 coupled to a motor 12 and a fluid housing 52 having at least one port 60. The port 60 includes a ball valve retainer region 69, a valve seat 73, and an occluder ball 71 disposed in the ball valve retainer region 69. During operation, the motor 12 forces the fluid in and out the fluid housing 52 and causes the occluder ball 71 to move from a first position whereby the fluid cannot pass through the port 60, to a second position whereby the fluid moves annular to and generally around the occluder ball 71. This movement creates a slight flow reversal that “breaks up” any blood clots that may form. The pumping system may be used as part of a cardiopulmonary bypass system, a ventricular assist device (VAD) and/or a heart pump.
摘要翻译：泵送系统10，如图1所示，提供生理脉动流，并包括控制器121，耦合到马达12的泵驱动头50和具有至少一个端口60的流体壳体52.端口60包括球阀保持器区域69，阀座73，以及设置在球阀保持器区域69中的阻塞球71.在操作期间，电动机12迫使流体进入和流出流体壳体52，并使得封堵器球71从第一位置移动，由此流体不能通过该端口 60到第二位置，由此流体环绕到闭塞器球71周围并且通常围绕闭塞球71.这种运动产生轻微的流动逆转，“分解”可能形成的任何血块。泵送系统可以用作体外循环系统，心室辅助装置（VAD）和/或心脏泵的一部分。

7. 发明授权

US5608221A Multi-head nuclear medicine camera for dual SPECT and PET imaging with monuniform attenuation correction 失效
标题翻译：多头核医学相机用于双重SPECT和PET成像与单位衰减校正
公开(公告)号：US5608221A
公开(公告)日：1997-03-04
申请号：US488871
申请日：1995-06-09
申请人： Hugo Bertelsen , Peter Nellemann , Matthew J. Murphy , Donald R. Wellnitz , Horace H. Hines
发明人： Hugo Bertelsen , Peter Nellemann , Matthew J. Murphy , Donald R. Wellnitz , Horace H. Hines
IPC分类号： G01T1/161 , G01T1/164 , G01T1/29 , G01T1/166
CPC分类号： G01T1/1615 , G01T1/1642 , G01T1/2985 , A61B6/037
摘要： A dual head nuclear camera system automatically switchable (and optimized) to perform either SPECT imaging or PET imaging that utilizes attenuation correction for nonuniform attenuation in SPECT or PET modes. The dual head detectors contain switchable triggering circuitry so that coincidence detection for PET imaging and non-coincidence detection for SPECT imaging is available. The system uses a variable integration technique with programmable integration interval; variable sized clusters for centroiding, use of dual integrators per PMT channel, the event detection and acquisition circuitry of the camera system is switchable for PET and SPECT imaging. In such a switchable SPECT/Pet dual head camera system, a mechanism and method is shown to perform transmission and emission scanning sessions with two line sources and two detectors wherein two sliding transmission detection windows are employed to differentiate between transmission and emission photons. Transmission and emission data can be collected simultaneously. This system provides that the dual transmission detection windows are each associated with a particular line source and move in synchronization. Further, the two line sources and the two detector windows all move in synchronization in the direction of the long axis of the object being scanned. In this configuration, the system can effectively reduce the amount of cross-talk detected by a detector.
摘要翻译：双头核相机系统可自动切换（优化），以执行SPECT成像或PET成像，利用衰减校正在SPECT或PET模式下进行不均匀衰减。双头检测器包含可切换的触发电路，因此PET成像的一致检测和SPECT成像的非重合检测是可用的。该系统采用可编程集成间隔的可变积分技术; 可变尺寸的集群用于重心，每个PMT通道使用双积分器，相机系统的事件检测和采集电路可切换到PET和SPECT成像。在这种可切换的SPECT /宠物双头摄像机系统中，示出了利用两个线路源和两个检测器执行传输和发射扫描会话的机制和方法，其中采用两个滑动传输检测窗口来区分传输和发射光子。传输和排放数据可以同时收集。该系统提供双传输检测窗口各自与特定的线路源相关联并且同步移动。此外，两条线源和两个检测器窗口都沿被扫描对象的长轴的方向同步移动。在该配置中，系统可以有效地减少由检测器检测到的串扰量。

8. 发明授权

US5376796A Proximity detector for body contouring system of a medical camera 失效
标题翻译：医用摄像机身体轮廓系统接近检测仪
公开(公告)号：US5376796A
公开(公告)日：1994-12-27
申请号：US981833
申请日：1992-11-25
申请人： David A. Chan , Robert L. Kay , Matthew J. Murphy , Steven M. Jones , Kenneth G. Bayer , Paul Hug , Horace H. Hines
发明人： David A. Chan , Robert L. Kay , Matthew J. Murphy , Steven M. Jones , Kenneth G. Bayer , Paul Hug , Horace H. Hines
IPC分类号： G01B11/24 , G01T1/164 , G01T1/166 , G01T1/20
CPC分类号： G01B11/2433 , G01T1/1648
摘要： A direct measurement system for proximity detection of a body profile for use within nuclear medicine. The measurement system includes two or three proximity detector units mounted on a gantry structure of a nuclear medicine camera which each emit an energy beam which is swept across a portion of a target body. Each detector is capable of directly measuring the distance from the proximity detector unit to the target body with a beam sample. The detectors then create a body profile of the target body which is used to minimize the distance between the collimator of a scanning camera and the target body surface thus improving image quality of the scanning camera. There is relative motion between the object and the gantry along a cranial-caudal axis of a target body for scanning successive body profiles. Successive body profiles are combined together to achieve a complete body contour of the target body. The proximity detector units are stationary with respect to movement of the scanning camera toward said target body. Body contour data is also used for attentuation correction.
摘要翻译：用于核医学中使用的身体轮廓的接近检测的直接测量系统。测量系统包括安装在核医学照相机的台架结构上的两个或三个接近检测器单元，每个发射能量束扫过目标体的一部分。每个检测器能够使用光束样本直接测量从接近检测器单元到目标体的距离。然后，检测器产生目标体的身体轮廓，其用于最小化扫描照相机的准直器与目标体表面之间的距离，从而改善扫描照相机的图像质量。沿着目标身体的颅尾轴线，物体和台架之间存在相对运动，用于扫描连续的身体轮廓。连续的身体轮廓组合在一起以实现目标身体的完整的身体轮廓。接近检测器单元相对于扫描照相机朝向所述目标体的运动是静止的。身体轮廓数据也用于注意校正。

9. 发明授权

US5763887A Tailored optical interface for scintillation camera detector 失效
标题翻译：用于闪烁相机检测器的定制光学接口
公开(公告)号：US5763887A
公开(公告)日：1998-06-09
申请号：US691585
申请日：1996-08-02
申请人： Matthew J. Murphy
发明人： Matthew J. Murphy
IPC分类号： G01T1/164 , G01T1/20
CPC分类号： G01T1/1642 , G01T1/2002 , A61B6/4258
摘要： A scintillation camera detector head comprises a scintillation crystal, a plurality of photomultiplier tubes (PMTs) optically coupled to the scintillation crystal, and a diffractive surface, such as a holographic optical element (HOE), optically coupled to the scintillation crystal. The diffractive surface preferentially reflects or redirects light from a scintillation event which impinges upon the surface toward one or more predetermined PMTs as a function of the angle of incidence or the location of the event. Light emitted under a peak PMT can be preferentially reflected or transmitted away from the peak PMT and toward the surrounding PMTs to reduce spatial resolution modulation. Alternatively, light impinging on the surface from an event can be directed toward the peak PMT and away from surrounding PMTs to achieve greater isolation of events.
摘要翻译：闪烁照相机检测器头包括闪烁晶体，与闪烁晶体光学耦合的多个光电倍增管（PMT）和光学耦合到闪烁晶体的衍射表面，例如全息光学元件（HOE）。衍射表面优选地将来自闪烁事件的光反射或重定向，作为入射角或事件位置的函数的一个或多个预定PMT的冲击表面。在峰值PMT下发射的光可以优先反射或远离峰值PMT并朝着周围的PMT发射以减少空间分辨率调制。或者，从事件撞击在表面上的光可以被引导到峰值PMT并远离周围的PMT以实现更大的事件隔离。

10. 发明授权

US08591448B2 Pressure monitoring within a fluid cassette 有权
标题翻译：流体盒内的压力监控
公开(公告)号：US08591448B2
公开(公告)日：2013-11-26
申请号：US12465327
申请日：2009-05-13
申请人： Edward T. Powers , Matthew J. Murphy , Michael Ragusa
发明人： Edward T. Powers , Matthew J. Murphy , Michael Ragusa
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3639 , A61M1/3472 , A61M2205/12 , A61M2205/3331 , A61M2205/7518 , A61M2205/7536
摘要： A fluid cassette for a blood processing system includes a cassette housing and a rigid structure. The cassette housing defines the structure of the cassette and has a fluid path at least partially extending through it. The fluid path is configured to allow a fluid to pass through the housing. The rigid structure defines a cavity that is in fluid communication with the fluid path. The rigid structure also has an interface for interfacing and/or connecting with a pressure monitoring device. The interface allows the pressure monitoring device to measure the pressure within the fluid path. The cavity has a volume of air located between the fluid path and the interface.
摘要翻译：用于血液处理系统的流体盒包括盒壳体和刚性结构。盒壳体限定了盒的结构，并且具有至少部分延伸通过其的流体路径。流体路径被配置为允许流体通过壳体。刚性结构限定了与流体路径流体连通的空腔。刚性结构还具有用于与压力监测装置进行接口和/或连接的接口。该界面允许压力监测装置测量流体路径内的压力。空腔具有位于流体路径和界面之间的空气体积。

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