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81. 发明授权

US08187234B2 Pressure activated safety valve with anti-adherent coating 有权
标题翻译：带有防粘涂层的压力安全阀
公开(公告)号：US08187234B2
公开(公告)日：2012-05-29
申请号：US10768571
申请日：2004-01-29
申请人： Karla Weaver , Paul DiCarlo
发明人： Karla Weaver , Paul DiCarlo
IPC分类号： A61M5/00
CPC分类号： A61M5/16881 , A61M39/22 , A61M39/24 , A61M2039/242 , A61M2039/2426
摘要： A pressure activated valve comprises a valve housing defining a lumen for receiving bodily fluids therein and a flexible membrane disposed in the valve housing. The flexible membrane includes a slit extending therethrough so that the flexible membrane may be moved between an open and a closed configuration based on fluid pressure within the lumen. A nonthrombogenic coating may be formed on fluid contacting surfaces of the flexible membrane.
摘要翻译：压力致动阀包括限定用于在其中接收体液的内腔的阀壳体和设置在阀壳体中的柔性膜。柔性膜包括延伸穿过其中的狭缝，使得柔性膜可以基于腔内的流体压力在开放和闭合构型之间移动。可以在柔性膜的流体接触表面上形成非凝血性涂层。

82. 发明申请

US20110172691A1 METHOD AND APPARATUS FOR TISSUE RESECTION 有权
标题翻译：方法和装置组织检查
公开(公告)号：US20110172691A1
公开(公告)日：2011-07-14
申请号：US13070321
申请日：2011-03-23
申请人： Arnold E. Oyola , Marcia Buiser , Paul DiCarlo
发明人： Arnold E. Oyola , Marcia Buiser , Paul DiCarlo
IPC分类号： A61B17/32 , A61N1/00
CPC分类号： A61B18/1482 , A61B17/00491 , A61B17/320068 , A61B17/3211 , A61B18/22 , A61B2017/00495
摘要： A resection device includes an elongated probe shaft and a tissue resection member disposed at a distal end of the elongated probe shaft. The tissue resection member has a cutting surface configured for being placed in contact with tissue. In one aspect of the invention, at least one ejection port is located adjacent to the cutting surface of the tissue resection member, wherein the at least one ejection port is coupled to a source of a polymerizable hemostasis-promoting material that is delivered to the resection site of interest. In certain embodiments, polymerization of the hemostasis-promoting material may be accelerated by application of heat, radiofrequency energy, or ultra violet light.
摘要翻译：切除装置包括细长的探针轴和设置在细长探针轴的远端处的组织切除部件。组织切除构件具有被配置为与组织接触的切割表面。在本发明的一个方面，至少一个喷射口位于组织切除部件的切割表面附近，其中至少一个喷射口连接到可输送到切除部分的可聚合止血促进材料的源感兴趣的网站在某些实施方案中，止血促进材料的聚合可以通过施加热，射频能量或紫外线加速。

83. 发明授权

US07962197B2 Radiation ablation tracking system and method 有权
标题翻译：辐射消融跟踪系统及方法
公开(公告)号：US07962197B2
公开(公告)日：2011-06-14
申请号：US12818086
申请日：2010-06-17
申请人： Robert F. Rioux , Paul DiCarlo
发明人： Robert F. Rioux , Paul DiCarlo
IPC分类号： A61B5/05
CPC分类号： A61N5/1049 , A61B18/1477 , A61B18/148 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61N5/1065 , A61N2005/1061
摘要： A system and method for treating a target tissue region (e.g., malignant tissue) is provided. A hyperthermic probe is placed into contact with the target tissue region, and the target tissue region is exposed to a therapeutic x-ray radiation beam. The probe is operated to increase the temperature of the target tissue region, thereby facilitating a therapeutic effect of the radiation beam. Image data of the probe containing a fiducial datum is acquired while in contact with the target tissue region, a position of the target tissue region within a treatment coordinate system is determined based on the fiducial datum, and the radiation beam is spatially adjusted relative to the target tissue region based on the determined position of the target tissue region.
摘要翻译：提供了用于治疗靶组织区域（例如，恶性组织）的系统和方法。将高温探针放置成与目标组织区域接触，并且将目标组织区域暴露于治疗性X射线辐射束。操作探针以增加靶组织区域的温度，从而有助于辐射束的治疗效果。在与目标组织区域接触的同时获取包含基准数据的探针的图像数据，基于基准原理确定处理坐标系内的目标组织区域的位置，并且相对于基于所确定的目标组织区域的位置的目标组织区域。

84. 发明申请

US20110060316A1 Tipped Ribbon Integrated Guidewire 审中-公开
标题翻译：尖端带状集成导丝
公开(公告)号：US20110060316A1
公开(公告)日：2011-03-10
申请号：US12554613
申请日：2009-09-04
申请人： Paul DiCarlo
发明人： Paul DiCarlo
IPC分类号： A61M25/09 , A61M25/098
CPC分类号： A61M25/09 , A61M2025/09133 , A61M2025/09166 , A61M2025/09191
摘要： A guidewire having a longitudinal axis includes an inner ribbon coil wound in a first direction, an outer ribbon coil wound in a second direction opposite the first direction wherein the inner ribbon coil is coaxially arranged within the outer ribbon coil and configured to prevent the inner ribbon coil from interlocking with the outer ribbon coil, and a plurality of connection points along the longitudinal axis of the guidewire wherein the plurality of connection points affixes the inner ribbon coil to the outer ribbon coil.
摘要翻译：具有纵向轴线的导丝线包括沿第一方向缠绕的内部带状线圈，沿与第一方向相反的第二方向缠绕的外部带状线圈，其中内部带状线圈同轴地布置在外部带状线圈内并且构造成防止内部带状物线圈与外部带状线圈互锁，以及沿着导丝的纵向轴线的多个连接点，其中多个连接点将内部带状线圈固定到外部带状线圈。

85. 发明授权

US07824365B2 Percutaneous access 失效
标题翻译：经皮进入
公开(公告)号：US07824365B2
公开(公告)日：2010-11-02
申请号：US10852247
申请日：2004-05-24
申请人： Brett T. Haarala , Brian Bergeron , Paul DiCarlo
发明人： Brett T. Haarala , Brian Bergeron , Paul DiCarlo
IPC分类号： A61M31/00
CPC分类号： A61M39/0247 , A61M2039/0261 , A61M2039/0264 , A61M2039/0279 , A61M2039/0282 , A61M2039/0288 , A61M2039/0291
摘要： Medical devices and related methods enable physicians and/or other medical personnel to access percutaneously the interior of a patient. One particular device includes a housing which defines a cavity, a first opening into the cavity, and a second opening into the cavity. The housing is implantable in a patient. The cavity is placed subcutaneously within the patient. The first opening is substantially flush with the surface of the skin of the patient and creates a percutaneous passageway from the exterior of the skin of the patient into the cavity, and the second opening creates a passageway from the cavity into the interior of the patient. A connector is coupled to the second opening and disposed substantially within the cavity to enable a connection between a first device and a second device disposed within the interior of the patient.
摘要翻译：医疗设备和相关方法使得医师和/或其他医务人员能够经皮通过患者的内部。一个特定装置包括限定空腔的壳体，进入空腔的第一开口和进入空腔的第二开口。外壳可植入患者体内。将腔体皮下放置在患者体内。第一开口基本上与患者皮肤表面平齐，并且产生从患者皮肤外部进入空腔的经皮通道，并且第二开口形成从空腔进入患者内部的通道。连接器联接到第二开口并且基本上设置在空腔内，以实现第一装置和设置在患者内部内的第二装置之间的连接。

86. 发明授权

US07799066B2 Devices and methods for AAA management 失效
标题翻译： AAA管理的设备和方法
公开(公告)号：US07799066B2
公开(公告)日：2010-09-21
申请号：US11891793
申请日：2007-08-13
申请人： Paul DiCarlo
发明人： Paul DiCarlo
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/90 , A61F2/95 , A61F2/958 , A61F2/966 , A61F2002/075 , A61F2002/9511
摘要： A method of treating an abdominal aortic aneurysm is disclosed. The method includes the steps of providing an endovascular graft configured to be disposed within an aorta of a patient and to be attached to an aortic wall to channel aortic blood flow therethrough; advancing a temporary stent catheter endovascularly to a location of the aneurysm, the catheter being attached to a temporary stent, the temporary stent and the graft being constrained by one or more constraining devices during advancement of the graft; removing the one or more constraining devices from the graft and temporary stent, to allow the temporary stent to stabilize the graft against the aortic wall; fixing the graft to the aortic wall; reconstraining the temporary stent with one of the one or more constraining devices; and withdrawing the temporary stent catheter, temporary stent and the one or more constraining devices, releasing the graft.
摘要翻译：公开了一种治疗腹主动脉瘤的方法。该方法包括以下步骤：提供构造成设置在患者的主动脉内并且附接到主动脉壁以将主动脉血流通过其中的血管内移植物; 将临时支架导管血管内推进到动脉瘤的位置，导管附接到临时支架，临时支架和移植物在移植物的推进期间被一个或多个约束装置约束; 从移植物和临时支架移除一个或多个约束装置，以允许临时支架将移植物抵靠主动脉壁稳定; 将移植物固定在主动脉壁上; 将所述临时支架与所述一个或多个约束装置中的一个重新约束; 并撤回临时支架导管，临时支架和一个或多个约束装置，释放移植物。

87. 发明授权

US07736671B2 Embolization 有权
标题翻译：栓塞
公开(公告)号：US07736671B2
公开(公告)日：2010-06-15
申请号：US10791552
申请日：2004-03-02
申请人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
发明人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
IPC分类号： A61K9/14
CPC分类号： A61L31/04 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/12186 , A61B17/42 , A61B2017/1205 , A61K9/0019 , A61K9/167 , A61L24/0015 , A61L24/0036 , A61L24/046 , A61L31/14 , A61L2300/62 , A61L2430/36 , Y10T428/2982 , Y10T428/2998
摘要： Embolization, as well as related particles, compositions, and methods, are disclosed.
摘要翻译：公开了栓塞，以及相关的颗粒，组合物和方法。

88. 发明申请

US20100036259A1 Uterine Infrared Thermal Imaging Device 审中-公开
标题翻译：子宫红外成像装置
公开(公告)号：US20100036259A1
公开(公告)日：2010-02-11
申请号：US12491496
申请日：2009-06-25
申请人： Paul DiCarlo , Jon T. McIntyre
发明人： Paul DiCarlo , Jon T. McIntyre
IPC分类号： A61B6/00
CPC分类号： A61B5/4318 , A61B5/0086 , A61B5/015 , A61B5/0261
摘要： A device for locating target tissue within a living body, comprises an elongate member extending from a proximal end which, when in an operative position, remains outside the body to a distal end which, when in the operative position, extends into the body to a location proximate to a target portion of tissue, the elongate member defining a working channel extending therethrough to a distal opening in the distal end and a radiation delivery apparatus delivering infrared radiation to a target area distal of the distal end of the elongate member in combination with a radiation receiving apparatus at a distal end of the elongate member receiving radiation reflected from the target area.
摘要翻译：一种用于在活体内定位靶组织的装置，包括从近端延伸的细长构件，所述近端在处于工作位置时保持在所述主体外部到远端，所述远端当处于所述操作位置时延伸到所述主体内时位于靠近组织的目标部分的位置，细长构件限定穿过其延伸到远端的远侧开口的工作通道，以及辐射递送装置，其将红外线辐射传递到细长构件的远端远侧的目标区域，在所述细长构件的远端处接收从所述目标区域反射的辐射的辐射接收装置。

89. 发明申请

US20090227964A1 Implantable Fluid Transfer Access Port 审中-公开
标题翻译：可植入流体传输接口
公开(公告)号：US20090227964A1
公开(公告)日：2009-09-10
申请号：US12367927
申请日：2009-02-09
申请人： Paul DiCarlo , Stephanie Dubay , Jeff Gray
发明人： Paul DiCarlo , Stephanie Dubay , Jeff Gray
IPC分类号： A61M5/42 , G08B21/00
CPC分类号： A61M39/0208 , A61M2039/0238 , A61M2205/581 , A61M2205/582
摘要： An implantable port comprises a port body forming a fluid reservoir and a septum sealing a proximal end of the reservoir in combination with a clicker member biased toward a first configuration, the clicker member being deformable via mechanical force applied thereto and configured so that, when subject to a force of at least a predetermined magnitude, the clicker member rapidly deforms away from the first configuration to a second configuration to provide one of an aural and tactile feedback to the user.
摘要翻译：可植入端口包括形成流体储存器的端口主体和密封储存器的近端的隔膜，其与朝向第一构造偏置的回弹元件组合，所述回弹元件可通过施加到其上的机械力而变形，并且被构造成使得当受试者达到至少预定大小的力，所述答题器构件迅速地从第一配置变形到第二配置，以向用户提供听觉和触觉反馈之一。

90. 发明申请

US20090054892A1 SYSTEM AND METHOD FOR PERFORMING ABLATION USING AN EXPANDABLE MEMBER 有权
标题翻译：使用可扩展成员执行抽取的系统和方法
公开(公告)号：US20090054892A1
公开(公告)日：2009-02-26
申请号：US12119010
申请日：2008-05-12
申请人： Robert F. Rioux , Paul DiCarlo
发明人： Robert F. Rioux , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/14 , A61B18/1482 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00238 , A61B2018/00255 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00702 , A61B2018/00875
摘要： An apparatus comprises a catheter, a conductive element and a balloon. The catheter has a lumen. The conductive element is disposed along the catheter. The balloon has an interior in fluid communication with the lumen of the catheter. The balloon is formed of a conductive material conductively coupled to the conductive element. The balloon has a collapsed configuration and an expanded configuration.
摘要翻译：一种装置包括导管，导电元件和气球。导管有一个内腔。导电元件沿导管设置。气囊具有与导管的内腔流体连通的内部。气球由导电性地耦合到导电元件的导电材料形成。气球具有收缩配置和扩展配置。

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