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1. 发明授权

US11890044B2 Pulmonary vein isolation balloon catheter 有权
公开(公告)号：US11890044B2
公开(公告)日：2024-02-06
申请号：US16467343
申请日：2017-12-05
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： Troy T. Tegg , Salo Arias , Derek Sutermeister
IPC分类号： A61B18/14 , A61B18/02 , A61B90/00 , A61B18/00 , A61M25/01
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/00166 , A61B2018/00255 , A61B2018/00351 , A61B2018/00375 , A61B2018/00577 , A61B2018/00791 , A61B2018/00946 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262 , A61B2090/064 , A61B2090/065 , A61B2218/002 , A61B2218/007 , A61M25/0116 , A61M25/0127 , A61M25/0136
摘要： The instant disclosure relates to electrophysiology catheters for tissue ablation. In particular, the instant disclosure relates to a cryogenic ablation balloon with safety features that facilitate identification of a leak into an interstitial space between inner and outer balloons as part of the ablation balloon catheter assembly, and prevents egress of cryogenic fluid out of the ablation balloon.

2. 发明授权

US11878128B2 Systems, devices and methods for performing medical procedures in the intestine 有权
公开(公告)号：US11878128B2
公开(公告)日：2024-01-23
申请号：US17384421
申请日：2021-07-23
申请人： Fractyl Health, Inc.
发明人： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
IPC分类号： A61B18/14 , A61M25/00 , A61B18/02 , A61F5/00 , A61B5/00 , A61B17/00 , A61B18/08 , A61B18/18 , A61M25/04 , A61N7/00 , A61B18/00 , A61B18/06 , A61B18/04 , A61N7/02 , A61B17/02 , A61B90/00 , A61B5/055 , A61B17/34 , A61B17/30 , A61B18/24
CPC分类号： A61M25/00 , A61B5/0036 , A61B5/0084 , A61B5/4255 , A61B5/4836 , A61B5/6852 , A61B5/6885 , A61B17/00234 , A61B18/02 , A61B18/082 , A61B18/1492 , A61B18/1815 , A61F5/0069 , A61F5/0079 , A61M25/04 , A61N7/00 , A61B5/0066 , A61B5/055 , A61B17/00491 , A61B17/0218 , A61B17/3478 , A61B18/06 , A61B18/24 , A61B2017/00004 , A61B2017/00022 , A61B2017/00199 , A61B2017/00269 , A61B2017/00818 , A61B2017/306 , A61B2018/00005 , A61B2018/00011 , A61B2018/00017 , A61B2018/0022 , A61B2018/00029 , A61B2018/00041 , A61B2018/00255 , A61B2018/00285 , A61B2018/00291 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00744 , A61B2018/00791 , A61B2018/00809 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00982 , A61B2018/0212 , A61B2018/046 , A61B2018/1861 , A61B2090/395 , A61B2090/3908 , A61B2090/3933 , A61B2218/002 , A61B2505/05 , A61B2560/0431 , A61B2562/227 , A61M25/0082 , A61M2210/1053 , A61M2210/1057 , A61M2210/1071 , A61M2210/1408 , A61N7/022
摘要： A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).

3. 发明授权

US11819229B2 Balloon surface photoacoustic pressure wave generation to disrupt vascular lesions 有权
公开(公告)号：US11819229B2
公开(公告)日：2023-11-21
申请号：US16884257
申请日：2020-05-27
申请人： Boston Scientific Scimed, Inc.
发明人： Roger W. McGowan , Daniel Frank Massimini , Haiping Shao , Christopher Smuk
IPC分类号： A61B17/22 , A61B18/24 , A61B90/30 , A61B18/00 , A61B18/22
CPC分类号： A61B17/2202 , A61B18/245 , A61B2017/22051 , A61B2017/22062 , A61B2017/22069 , A61B2018/0022 , A61B2018/00255 , A61B2018/2261 , A61B2018/2294 , A61B2090/306
摘要： A photoacoustic catheter adapted for placement within a blood vessel having a vessel wall includes an elongate shaft, a balloon and a photoacoustic transducer. The elongate shaft can extend from a proximal region to a distal region. The elongate shaft can include a light guide that is configured to be placed in optical communication with a light source. The balloon is coupled to the elongate shaft, and can be configured to expand from a collapsed configuration suitable for advancing the photoacoustic catheter through a patient's vasculature to a first expanded configuration suitable for anchoring the photoacoustic catheter in position relative to a treatment site. The photoacoustic transducer can be disposed on a surface of the balloon and in optical communication with the light guide. The photoacoustic transducer can include a light-absorbing material and a thermal expansion material.

4. 发明授权

US11786297B2 Minimally invasive articulating assembly having ablation capabilities 有权
公开(公告)号：US11786297B2
公开(公告)日：2023-10-17
申请号：US16633934
申请日：2018-07-25
申请人： INNOBLATIVE DESIGNS, INC.
发明人： Robert F. Rioux , Alyssa Bailey , Tyler Wanke , Ryan M. Bean
IPC分类号： A61B18/14 , A61B90/00 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/1206 , A61B90/37 , A61B2018/00255 , A61B2018/00541 , A61B2018/00577 , A61B2018/00791 , A61B2018/00875 , A61B2018/126 , A61B2090/378 , A61B2090/3762 , A61B2218/002
摘要： The present invention is a minimally invasive articulating configured to be advanced through tortuous anatomy, particularly within a lung, and subsequently deliver at least two separately deployable ablation devices to a target site located at a bifurcated section of the lung (i.e., at a bronchial airway bifurcation). The pair of ablation devices are separately steerable towards respective first and second pathways extending from the bifurcation, such that each of the ablation devices can be positioned on either side of a target tissue proximate the bifurcation. The first and second ablation devices include expandable distal tips configured to transition to a deployed configuration, in which each expands in diameter and is configured to apply a degree of compression and/or RF energy emission to target lung tissue (i.e., diseased tissue, such as cancer or emphysema-related damaged tissue) for subsequent ablation thereof.

5. 发明授权

US10610663B2 Systems, devices and methods for performing medical procedures in the intestine 有权
公开(公告)号：US10610663B2
公开(公告)日：2020-04-07
申请号：US15683713
申请日：2017-08-22
申请人： Fractyl Laboratories, Inc.
发明人： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
IPC分类号： A61B18/14 , A61M25/00 , A61B18/02 , A61F5/00 , A61B5/00 , A61B17/00 , A61B18/08 , A61B18/18 , A61M25/04 , A61N7/00 , A61B18/00 , A61B18/06 , A61B18/04 , A61N7/02 , A61B17/02 , A61B90/00 , A61B5/055 , A61B17/34 , A61B17/30 , A61B18/24
CPC分类号： A61M25/00 , A61B5/0084 , A61B5/4255 , A61B5/4836 , A61B5/6852 , A61B5/6885 , A61B17/00234 , A61B18/02 , A61B18/082 , A61B18/1492 , A61B18/1815 , A61F5/0069 , A61F5/0079 , A61M25/04 , A61N7/00 , A61B5/0066 , A61B5/055 , A61B17/00491 , A61B17/0218 , A61B17/3478 , A61B18/06 , A61B18/24 , A61B2017/00004 , A61B2017/00022 , A61B2017/00199 , A61B2017/00269 , A61B2017/00818 , A61B2017/306 , A61B2018/00005 , A61B2018/00011 , A61B2018/00017 , A61B2018/0022 , A61B2018/00029 , A61B2018/00041 , A61B2018/00255 , A61B2018/00285 , A61B2018/00291 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00744 , A61B2018/00791 , A61B2018/00809 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00982 , A61B2018/0212 , A61B2018/046 , A61B2018/1861 , A61B2090/395 , A61B2090/3908 , A61B2090/3933 , A61B2218/002 , A61B2505/05 , A61B2560/0431 , A61B2562/227 , A61M25/0082 , A61M2210/1053 , A61M2210/1057 , A61M2210/1071 , A61M2210/1408 , A61N7/022
摘要： A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).

6. 发明授权

US09888953B2 Nested balloon cryotherapy 有权
公开(公告)号：US09888953B2
公开(公告)日：2018-02-13
申请号：US14712405
申请日：2015-05-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Frank Ingle , Rebecca Tin , Robert F. Bencini , James Mazzone
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00255 , A61B2018/0212
摘要： A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.

7. 发明申请

US20170354461A1 CATHETER APPARATUSES FOR MODULATION OF NERVES IN COMMUNICATION WITH THE PULMONARY SYSTEM AND ASSOCIATED SYSTEMS AND METHODS 审中-公开
公开(公告)号：US20170354461A1
公开(公告)日：2017-12-14
申请号：US15516349
申请日：2015-11-14
申请人： MEDTRONIC ARDIAN LUXEMBOURG
发明人： Martin ROTHMAN , Paul COATES
IPC分类号： A61B18/14 , G01R5/26 , A61B18/02 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/0206 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/0025 , A61B2018/00255 , A61B2018/00267 , A61B2018/00279 , A61B2018/00351 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00839 , A61B2018/0212 , A61B2018/0262 , A61B2018/1407 , A61B2090/3966 , A61B2218/002 , A61N2007/0026 , G01R5/26
摘要： Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.

8. 发明申请

US20160051309A1 CRYOGENIC BALLOON DEVICE WITH RADIOFREQUENCY TIP 有权
公开(公告)号：US20160051309A1
公开(公告)日：2016-02-25
申请号：US14932565
申请日：2015-11-04
申请人： Medtronic CryoCath LP
发明人： Jean-Pierre LALONDE
IPC分类号： A61B18/02 , A61B18/14
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

9. 发明授权

US09060754B2 Neuromodulation cryotherapeutic devices and associated systems and methods 有权
标题翻译：神经调节冷冻治疗装置及相关系统和方法
公开(公告)号：US09060754B2
公开(公告)日：2015-06-23
申请号：US13279328
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00232 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.
摘要翻译：本文公开了神经调节冷冻治疗装置及相关系统和方法。根据特定实施例构造的冷冻治疗装置包括细长轴和在轴的远端部分处的冷却组件。轴可以被配置为将血管内远端部分定位在肾动脉内或其他邻近肾动脉处的处置部位。冷冻治疗装置还可以包括被配置为将液体制冷剂运送到冷却组件的供应管腔。冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。

10. 发明申请

US20150094701A1 TRIPLE BALLOON CATHETER 有权
标题翻译：三重气球导管
公开(公告)号：US20150094701A1
公开(公告)日：2015-04-02
申请号：US14564907
申请日：2014-12-09
申请人： Medtronic CryoCath LP
发明人： Jean-Luc PAGEARD
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212
摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.
摘要翻译：本发明有利地提供了用于低温切除左心房内的大面积组织的方法和系统。在示例性实施例中，冷冻治疗装置包括导管主体，近端和远端; 第一个管腔第二个管腔以及可从第一直径扩展到第二直径的消融元件，所述消融元件具有与心脏组织的不平坦表面形貌一致的表面部分。消融元件可以包括一个或多个可变形的球囊和/或柔性元件。球囊的表面可以通过调节一个或多个气囊内的压力而进一步成形。在一种示例性方法中，提供组织消融装置，并且使用该装置消除左心房中的组织，由此通过冷冻组织产生消融。

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