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1. 发明授权

US09888953B2 Nested balloon cryotherapy 有权
公开(公告)号：US09888953B2
公开(公告)日：2018-02-13
申请号：US14712405
申请日：2015-05-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Frank Ingle , Rebecca Tin , Robert F. Bencini , James Mazzone
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00255 , A61B2018/0212
摘要： A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.

2. 发明申请

US20170354461A1 CATHETER APPARATUSES FOR MODULATION OF NERVES IN COMMUNICATION WITH THE PULMONARY SYSTEM AND ASSOCIATED SYSTEMS AND METHODS 审中-公开
公开(公告)号：US20170354461A1
公开(公告)日：2017-12-14
申请号：US15516349
申请日：2015-11-14
申请人： MEDTRONIC ARDIAN LUXEMBOURG
发明人： Martin ROTHMAN , Paul COATES
IPC分类号： A61B18/14 , G01R5/26 , A61B18/02 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/0206 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/0025 , A61B2018/00255 , A61B2018/00267 , A61B2018/00279 , A61B2018/00351 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00839 , A61B2018/0212 , A61B2018/0262 , A61B2018/1407 , A61B2090/3966 , A61B2218/002 , A61N2007/0026 , G01R5/26
摘要： Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.

3. 发明申请

US20160051309A1 CRYOGENIC BALLOON DEVICE WITH RADIOFREQUENCY TIP 有权
公开(公告)号：US20160051309A1
公开(公告)日：2016-02-25
申请号：US14932565
申请日：2015-11-04
申请人： Medtronic CryoCath LP
发明人： Jean-Pierre LALONDE
IPC分类号： A61B18/02 , A61B18/14
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

4. 发明授权

US09060754B2 Neuromodulation cryotherapeutic devices and associated systems and methods 有权
标题翻译：神经调节冷冻治疗装置及相关系统和方法
公开(公告)号：US09060754B2
公开(公告)日：2015-06-23
申请号：US13279328
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00232 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.
摘要翻译：本文公开了神经调节冷冻治疗装置及相关系统和方法。根据特定实施例构造的冷冻治疗装置包括细长轴和在轴的远端部分处的冷却组件。轴可以被配置为将血管内远端部分定位在肾动脉内或其他邻近肾动脉处的处置部位。冷冻治疗装置还可以包括被配置为将液体制冷剂运送到冷却组件的供应管腔。冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。

5. 发明申请

US20150094701A1 TRIPLE BALLOON CATHETER 有权
标题翻译：三重气球导管
公开(公告)号：US20150094701A1
公开(公告)日：2015-04-02
申请号：US14564907
申请日：2014-12-09
申请人： Medtronic CryoCath LP
发明人： Jean-Luc PAGEARD
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212
摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.
摘要翻译：本发明有利地提供了用于低温切除左心房内的大面积组织的方法和系统。在示例性实施例中，冷冻治疗装置包括导管主体，近端和远端; 第一个管腔第二个管腔以及可从第一直径扩展到第二直径的消融元件，所述消融元件具有与心脏组织的不平坦表面形貌一致的表面部分。消融元件可以包括一个或多个可变形的球囊和/或柔性元件。球囊的表面可以通过调节一个或多个气囊内的压力而进一步成形。在一种示例性方法中，提供组织消融装置，并且使用该装置消除左心房中的组织，由此通过冷冻组织产生消融。

6. 发明申请

US20150005766A1 SYSTEM AND METHOD FOR PERFORMING ABLATION USING AN EXPANDABLE MEMBER 审中-公开
公开(公告)号：US20150005766A1
公开(公告)日：2015-01-01
申请号：US14481567
申请日：2014-09-09
申请人： Boston Scientific Scimed, Inc.
发明人： Robert F. RIOUX , Paul DiCARLO
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/14 , A61B18/1482 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00238 , A61B2018/00255 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00702 , A61B2018/00875
摘要： An apparatus comprises a catheter, a conductive element and a balloon. The catheter has a lumen. The conductive element is disposed along the catheter. The balloon has an interior in fluid communication with the lumen of the catheter. The balloon is formed of a conductive material conductively coupled to the conductive element. The balloon has a collapsed configuration and an expanded configuration.

7. 发明申请

US20120303011A1 Catheters and Methods for Identification and Treatment of Bodily Passages 审中-公开
标题翻译：身体通路识别和治疗的导管和方法
公开(公告)号：US20120303011A1
公开(公告)日：2012-11-29
申请号：US13304432
申请日：2011-11-25
申请人： Darin Schaeffer
发明人： Darin Schaeffer
IPC分类号： A61B18/18
CPC分类号： A61B18/24 , A61B2018/0022 , A61B2018/00255
摘要： Catheters useful in the identification and treatment of bodily passages, such as sinus cavities, are provided. A catheter includes an elongate main body defining an inflation lumen and an optic lumen, an inflatable balloon attached to the distal end of the main body, and a fiber optic disposed in the optic lumen. When connected to a light source, the fiber optic emits light radially along a portion of the balloon and axially from the distal end of the main body. Methods of identifying and treating bodily passages, such as sinus cavities, are also described.
摘要翻译：提供了用于识别和治疗身体通道（如窦腔）的导管。导管包括限定充气腔和视腔的细长主体，附接到主体的远端的可充气气囊和设置在光腔中的光纤。当连接到光源时，光纤沿着球囊的一部分径向地发射光并且从主体的远端轴向发射光。还描述了识别和处理身体通道如窦腔的方法。

8. 发明申请

US20120165802A1 METHOD AND SYSTEM TO PREVENT COMPLETE OBSTRUCTION IN CATHETER IN CASE OF A KINK 有权
标题翻译：用于防止触发器中导线器完全阻塞的方法和系统
公开(公告)号：US20120165802A1
公开(公告)日：2012-06-28
申请号：US12978701
申请日：2010-12-27
申请人： Jean-Pierre LALONDE
发明人： Jean-Pierre LALONDE
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00166 , A61B2018/00214 , A61B2018/00255 , A61B2018/00791 , A61B2018/0212 , A61B2018/0262 , A61M2025/0059
摘要： A medical device comprising a shaft having a kink radius; a tube disposed within the shaft; a fluid source in fluid communication with the tube; an elongate member disposed within the tube, and the elongate member imparting a kink radius on the tube, the imparted kink radius of the tube being larger than the kink radius of the shaft.
摘要翻译：一种医疗装置，包括具有扭结半径的轴; 设置在所述轴内的管; 与管流体连通的流体源; 设置在管内的细长构件，并且细长构件在管上赋予扭结半径，管的赋予扭结半径大于轴的扭结半径。

9. 发明授权

US07172589B2 Cryo ablation coil 有权
标题翻译：冷冻消融线圈
公开(公告)号：US07172589B2
公开(公告)日：2007-02-06
申请号：US11094863
申请日：2005-03-31
申请人： Daniel M. Lafontaine
发明人： Daniel M. Lafontaine
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2017/22051 , A61B2018/00017 , A61B2018/0022 , A61B2018/00255 , A61B2018/0212 , A61B2018/0262
摘要： The present invention pertains to devices for causing cold-induced necrosis or apoptosis. The present invention includes a cryo therapy apparatus including a core member; a cryoplasty tube coupled to the core member, the cryoplasty tube having a proximal end and a distal end; wherein the distal end includes a coil disposed about at least a portion of the tubular sheath, the coil including at least one opening; an outer tube disposed over at least a portion of the cryoplasty tube; and a cooling member disposed over the coil and coupled to the outer tube. A method of causing cold-induced necrosis is also disclosed.
摘要翻译：本发明涉及引起冷诱导的坏死或凋亡的装置。本发明包括一种包括核心部件的冷冻治疗装置; 冷冻成形术管，其耦合到所述芯构件，所述冷冻成形术管具有近端和远端; 其中所述远端包括围绕所述管状护套的至少一部分设置的线圈，所述线圈包括至少一个开口; 设置在所述冷冻成形术管的至少一部分上的外管; 以及设置在所述线圈上并联接到所述外管的冷却构件。还公开了引起冷诱导坏死的方法。

10. 发明申请

US20180221622A1 SYSTEMS, DEVICES AND METHODS FOR PERFORMING MEDICAL PROCEDURES IN THE INTESTINE 审中-公开
公开(公告)号：US20180221622A1
公开(公告)日：2018-08-09
申请号：US15812969
申请日：2017-11-14
申请人： Fractyl Laboratories, Inc.
发明人： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
IPC分类号： A61M25/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B5/00 , A61F5/00 , A61N7/00 , A61B17/00 , A61M25/04 , A61B18/02 , A61B18/00 , A61B90/00 , A61B18/24 , A61B18/06 , A61B17/02 , A61B5/055 , A61B18/04 , A61N7/02
CPC分类号： A61M25/00 , A61B5/0066 , A61B5/0084 , A61B5/055 , A61B5/4255 , A61B5/4836 , A61B5/6852 , A61B5/6885 , A61B17/00234 , A61B17/00491 , A61B17/0218 , A61B17/3478 , A61B18/02 , A61B18/06 , A61B18/082 , A61B18/1492 , A61B18/1815 , A61B18/24 , A61B2017/00004 , A61B2017/00022 , A61B2017/00199 , A61B2017/00269 , A61B2017/00818 , A61B2017/306 , A61B2018/00005 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00041 , A61B2018/0022 , A61B2018/00255 , A61B2018/00285 , A61B2018/00291 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00744 , A61B2018/00791 , A61B2018/00809 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00982 , A61B2018/0212 , A61B2018/046 , A61B2018/1861 , A61B2090/3908 , A61B2090/3933 , A61B2090/395 , A61B2218/002 , A61B2505/05 , A61B2560/0431 , A61B2562/227 , A61F5/0069 , A61F5/0079 , A61M25/0082 , A61M25/04 , A61M2210/1053 , A61M2210/1057 , A61M2210/1071 , A61M2210/1408 , A61N7/00 , A61N7/022
摘要： A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).

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