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1. 发明申请

US20110257608A1 Multi-Slit High Flow Valve 审中-公开
标题翻译：多槽高流量阀
公开(公告)号：US20110257608A1
公开(公告)日：2011-10-20
申请号：US13170511
申请日：2011-06-28
申请人： Thomas V. Casey, II
发明人： Thomas V. Casey, II
IPC分类号： A61M25/14
CPC分类号： A61M25/007 , A61M39/24
摘要： A valve may include (a) a housing defining a valve lumen adapted for fluid connection with a lumen of a catheter; (b) a substantially conical valve member coupled to the housing and extending across the valve lumen to control flow therethrough; (c) a plurality of slits extending through the valve member and separated from one another circumferentially around the valve member; and (d) a ramp formed within a distal end of the valve lumen extending proximally from a distal tip of the valve member toward a ramp vertex separated from the distal tip by a predetermined distance.
摘要翻译：阀可以包括（a）限定适于与导管的内腔流体连接的阀腔的壳体; （b）基本上圆锥形的阀构件，其联接到所述壳体并延伸穿过所述阀腔以控制流过其中的流体; （c）多个狭缝，其延伸穿过所述阀构件并沿所述阀构件周向地彼此分离; 和（d）形成在所述阀腔的远端内的斜坡，其从所述阀构件的远侧末端向近端延伸到从所述远侧尖端分离预定距离的斜坡顶点。

2. 发明申请

US20110172644A1 MULTI LAYER COEXTRUDED CATHETER SHAFT 审中-公开
标题翻译：多层COEXTREDED导管轴
公开(公告)号：US20110172644A1
公开(公告)日：2011-07-14
申请号：US13071660
申请日：2011-03-25
申请人： Michael S. Zanoni , Thomas V. Casey, II , Brian F. Nentwick , Daniel K. Recinella , William M. Appling
发明人： Michael S. Zanoni , Thomas V. Casey, II , Brian F. Nentwick , Daniel K. Recinella , William M. Appling
IPC分类号： A61M25/098
CPC分类号： A61L29/18 , A61M1/3653 , A61M1/3659 , A61M25/0009 , A61M25/0045 , A61M25/0054 , A61M25/0108
摘要： A central venous catheter is provided having an outer tubular member and an inner tubular member that are preferably formed as a single integrated tube containing polymer material of different durometer and varying amounts of radiopaque filler material. The polymer durometer of the inner tubular member is higher than the polymer durometer of the outer tubular member. The percentage by weight of the filler material contained in the inner tubular member is higher than that of the outer tubular member. The combination of the higher durometer inner tubular member and the lower durometer outer tubular member along the length of the tube provides the desired tensile strength, hardness, chemical resistance and fatigue resistance and at the same time provides the desired flexibility and radiopacity.
摘要翻译：中央静脉导管设置有外管状构件和内管状构件，其优选地形成为包含不同硬度和不同量的不透射线填充材料的聚合物材料的单个整体管。内部管状构件的聚合物硬度计高于外部管状构件的聚合物硬度计。包含在内管状构件中的填充材料的重量百分比高于外管状构件的重量百分比。较高硬度的内部管状构件和下部硬度的外部管状构件沿着管的长度的组合提供期望的拉伸强度，硬度，耐化学性和抗疲劳性，并且同时提供期望的柔性和不透射线性。

3. 发明申请

US20100209522A1 Embolization 有权
公开(公告)号：US20100209522A1
公开(公告)日：2010-08-19
申请号：US12769172
申请日：2010-04-28
申请人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
发明人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
IPC分类号： A61K9/14 , A61P7/00
CPC分类号： A61L31/04 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/12186 , A61B17/42 , A61B2017/1205 , A61K9/0019 , A61K9/167 , A61L24/0015 , A61L24/0036 , A61L24/046 , A61L31/14 , A61L2300/62 , A61L2430/36 , Y10T428/2982 , Y10T428/2998
摘要： Embolization, as well as related particles, compositions, and methods, are disclosed.

4. 发明授权

US07727555B2 Particles 失效
标题翻译：粒子
公开(公告)号：US07727555B2
公开(公告)日：2010-06-01
申请号：US11111511
申请日：2005-04-21
申请人： Paul DiCarlo , Janel Lanphere , Thomas V. Casey, II , Marcia Buiser , Erin McKenna
发明人： Paul DiCarlo , Janel Lanphere , Thomas V. Casey, II , Marcia Buiser , Erin McKenna
IPC分类号： A61K9/16 , A61K9/32
CPC分类号： B01J13/04 , A61K9/1694 , A61K41/00 , B01J2/02 , B01J2/18 , Y10T428/2984
摘要： Particles and related methods are disclosed. In some embodiments, a method of making particles can include forming a stream of a mixture including first and second materials, exposing the stream to a vibration, and treating the stream to form particles. The vibration can have, for example, a sinusoidal, triangular, and/or sawtooth waveform.
摘要翻译：公开了颗粒和相关方法。在一些实施方案中，制备颗粒的方法可以包括形成包含第一和第二材料的混合物流，将流暴露于振动，以及处理流以形成颗粒。振动可以具有例如正弦，三角和/或锯齿波形。

5. 发明申请

US20100109178A1 EMBOLIZATION 有权
标题翻译：嵌入
公开(公告)号：US20100109178A1
公开(公告)日：2010-05-06
申请号：US12652552
申请日：2010-01-05
申请人： Janel Lanphere , Marcia Buiser , Thomas V. Casey, II
发明人： Janel Lanphere , Marcia Buiser , Thomas V. Casey, II
IPC分类号： B29B9/00
CPC分类号： A61B17/12022 , A61B17/12104 , A61B17/12109 , A61B17/12113 , A61B17/12186 , A61B17/1219 , A61B2017/1205 , A61J3/07 , B01J13/046
摘要： Embolization, as well as related particles and methods, are described.
摘要翻译：描述了栓塞以及相关的颗粒和方法。

6. 发明授权

US07611542B2 Tissue treatment 失效
标题翻译：组织治疗
公开(公告)号：US07611542B2
公开(公告)日：2009-11-03
申请号：US11555413
申请日：2006-11-01
申请人： George Bourne , Marcia S. Buiser , Thomas V. Casey, II , Steve Keenan , Janel L. Lanphere , Jianmin Li , Erin P. McKenna , Zarouhi Minasian , Doreen Rao
发明人： George Bourne , Marcia S. Buiser , Thomas V. Casey, II , Steve Keenan , Janel L. Lanphere , Jianmin Li , Erin P. McKenna , Zarouhi Minasian , Doreen Rao
IPC分类号： A61F2/36
CPC分类号： A61F2/0036 , A61K9/1635 , A61K49/0452 , A61L24/001 , A61L24/0036 , A61L24/06 , A61L27/16 , A61L27/50 , A61L31/048 , A61L2430/36 , C08J3/12 , C08J3/24 , C08J2329/04 , C08L29/04
摘要： A method of treating tissue includes placing substantially spherical polymer particles in the tissue. The particles include an interior region having relatively large pores and a first region substantially surrounding the interior having fewer relatively large pores than the interior region.
摘要翻译：治疗组织的方法包括将基本上球形的聚合物颗粒置于组织中。颗粒包括具有相对较大孔的内部区域，并且基本上围绕内部的第一区域具有比内部区域更少的相对较大的孔。

7. 发明授权

US07588825B2 Embolic compositions 有权
标题翻译：栓塞组成
公开(公告)号：US07588825B2
公开(公告)日：2009-09-15
申请号：US10700970
申请日：2003-11-04
申请人： Barbara Bell , Thomas V. Casey, II , William J. Shaw
发明人： Barbara Bell , Thomas V. Casey, II , William J. Shaw
IPC分类号： B32B5/66
CPC分类号： A61F2/02 , A61B17/12022 , A61B17/12104 , A61B17/12109 , A61B17/1215 , A61B17/12186 , A61B17/1219 , A61B2017/00867 , A61B2017/1205 , A61K9/0019 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2996 , Y10T428/2998
摘要： Embolic compositions and methods of delivering the compositions are disclosed. In some embodiments, an embolic composition includes a first collection of particles having a first shape, and a second collection of particles having a second shape different than the first shape.
摘要翻译：公开了栓塞组合物和递送组合物的方法。在一些实施例中，栓塞组合物包括具有第一形状的第一颗粒集合和具有不同于第一形状的第二形状的颗粒的第二集合。

8. 发明授权

US07449236B2 Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient 有权
标题翻译：包含聚乙烯醇的多孔聚合物颗粒并具有内表面孔隙度梯度
公开(公告)号：US07449236B2
公开(公告)日：2008-11-11
申请号：US10637130
申请日：2003-08-08
申请人： Janel L. Lanphere , Ernest J. Pierre , Greg Kapoglis , Thomas V. Casey, II
发明人： Janel L. Lanphere , Ernest J. Pierre , Greg Kapoglis , Thomas V. Casey, II
IPC分类号： B32B5/16 , A61K9/14 , A61K31/80 , A61K31/745
CPC分类号： A61K9/1635 , A61F2/0036 , A61K9/1652 , A61K49/0452 , A61L24/001 , A61L24/0036 , A61L24/06 , A61L27/16 , A61L27/50 , A61L31/048 , A61L2430/36 , C08J3/12 , C08J3/24 , C08J2305/00 , Y10S514/951 , Y10S514/964 , Y10T428/2982 , C08L29/04
摘要： Embolic particles, as well as their methods of use and manufacture, are described.
摘要翻译：描述了栓塞颗粒，以及它们的使用和制造方法。

9. 发明授权

US07131997B2 Tissue treatment 有权
公开(公告)号：US07131997B2
公开(公告)日：2006-11-07
申请号：US10231664
申请日：2002-08-30
申请人： George Bourne , Marcia S. Buiser , Thomas V. Casey, II , Steve Keenan , Janel L. Lanphere , Jianmin Li , Erin P. McKenna , Zarouhi Minasian , Doreen Rao
发明人： George Bourne , Marcia S. Buiser , Thomas V. Casey, II , Steve Keenan , Janel L. Lanphere , Jianmin Li , Erin P. McKenna , Zarouhi Minasian , Doreen Rao
IPC分类号： A61F2/36
CPC分类号： A61F2/0036 , A61K9/1635 , A61K49/0452 , A61L24/001 , A61L24/0036 , A61L24/06 , A61L27/16 , A61L27/50 , A61L31/048 , A61L2430/36 , C08J3/12 , C08J3/24 , C08J2329/04 , C08L29/04
摘要： A method of treating tissue includes placing substantially spherical polymer particles in the tissue. The particles include an interior region having relatively large pores and a first region substantially surrounding the interior having fewer relatively large pores than the interior region.

10. 发明授权

US08445022B2 Embolization 有权
标题翻译：栓塞
公开(公告)号：US08445022B2
公开(公告)日：2013-05-21
申请号：US13491915
申请日：2012-06-08
申请人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
发明人： Paul DiCarlo , Thomas V. Casey, II , Stephan P. Mangin
IPC分类号： A61K9/14
CPC分类号： A61L31/04 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/12186 , A61B17/42 , A61B2017/1205 , A61K9/0019 , A61K9/167 , A61L24/0015 , A61L24/0036 , A61L24/046 , A61L31/14 , A61L2300/62 , A61L2430/36 , Y10T428/2982 , Y10T428/2998
摘要： Embolization, as well as related particles, compositions, and methods, are disclosed.
摘要翻译：公开了栓塞，以及相关的颗粒，组合物和方法。

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