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71. 发明授权

US08893907B2 Stopping device and container comprising such a device 有权
标题翻译：停止包括这种装置的装置和容器
公开(公告)号：US08893907B2
公开(公告)日：2014-11-25
申请号：US14122927
申请日：2012-06-05
申请人： Antoine Aneas
发明人： Antoine Aneas
IPC分类号： B65D51/18 , B65D51/24 , B65D55/10 , B65D41/58
CPC分类号： B65D51/18 , B65D41/58 , B65D51/241 , B65D55/10 , B65D2101/0023
摘要： A stopping device for a container, comprising a circular stopper for closing the neck of the container, and a cap comprising a synthetic material that covers the neck and the stopper positioned in the neck, the cap comprising a cover and a ring for surrounding the stopper and the neck, the ring having a minimum inner diameter larger than the maximum diameter of the stopper, the ring and the cover being produced as a single component and connected by breakable bridges distributed over a circumference of the ring with an inner diameter that is larger than or equal to the maximum diameter of the stopper, and first locking tabs formed on the inside of the ring facing windows that are radially open towards the outside, and second locking tabs facing a closed part, each second tab formed between two first tabs, facing a strip of material separating windows.
摘要翻译：一种用于容器的止动装置，包括用于封闭容器的颈部的圆形止动器和包括覆盖颈部的合成材料和位于颈部中的止动件的帽，该帽包括盖和用于围绕塞子的环颈部，环的最小内径大于止动件的最大直径，环和盖被制造为单个部件，并且通过分布在环的圆周上的可分裂的桥连接，内径较大以及形成在朝向外侧径向开口的面向环的窗口的内侧上的第一锁定突出部以及面向封闭部分的第二锁定突片，每个第二突片形成在两个第一突出部之间，面对一条分隔窗的材料条。

72. 发明申请

US20130312373A1 METHODS FOR SEALING PHARMACEUTICAL VIALS 有权
标题翻译：密封药液的方法
公开(公告)号：US20130312373A1
公开(公告)日：2013-11-28
申请号：US13944242
申请日：2013-07-17
申请人： Genesis Packaging Technologies
发明人： F. William Bogle , Roger P. Asselta
IPC分类号： B65B7/28
CPC分类号： B65B7/28 , A61J1/1406 , A61J1/1412 , B65D51/002 , B65D51/241
摘要： A capping system and method of use for sealing injectable drugs within vials is disclosed. The system includes a closure assembly and a locking cap. The closure assembly includes a retainer member and a resilient stopper located within the retainer member. The retainer member is arranged to be disposed on the vial whereupon a gap results between the stopper and the vial. The retainer member is movable to close that gap. The locking cap is used to permanently seal the vial.
摘要翻译：公开了一种用于密封小瓶内的可注射药物的封盖系统和方法。该系统包括封闭组件和锁定帽。闭合组件包括保持构件和位于保持构件内的弹性塞子。保持器构件布置成设置在小瓶上，由此在塞子和小瓶之间产生间隙。保持构件可移动以封闭该间隙。锁盖用于永久密封小瓶。

73. 发明授权

US08574213B2 Process for preparing a lyophilized material 有权
标题翻译：制备冻干物质的方法
公开(公告)号：US08574213B2
公开(公告)日：2013-11-05
申请号：US13507571
申请日：2012-07-11
申请人： Jacques Thilly , Christian Vandecasserie
发明人： Jacques Thilly , Christian Vandecasserie
IPC分类号： A61B19/00 , A61M5/32
CPC分类号： B65D51/241 , F26B5/06
摘要： A process for preparing a lyophilized material, providing a container having a penetrable envelope and containing the material in a carrier liquid, whereby the penetrable region is penetrated with a penetrator which provides a conduit through the envelope, and the carrier liquid is evaporated out of the container via the conduit, after which the penetrator is withdrawn.
摘要翻译：一种用于制备冻干材料的方法，提供具有可穿透外壳并容纳载体液体的容器的容器，由此可穿透区域穿透穿透器，该穿透器通过外壳提供导管，并且载体液体从容器经过导管，之后将穿透器取出。

74. 发明申请

US20130233822A1 DEVICE FOR STOPPING A CONTAINER, AND CONTAINER PROVIDED WITH SUCH A DEVICE 有权
标题翻译：用于停止集装箱的装置，以及用这种装置提供的集装箱
公开(公告)号：US20130233822A1
公开(公告)日：2013-09-12
申请号：US13883465
申请日：2011-11-22
申请人： Antoine Aneas
发明人： Antoine Aneas
IPC分类号： B65D41/28 , B65D41/14 , A61J1/14
CPC分类号： B65D41/28 , A61J1/1412 , B65D41/14 , B65D51/002 , B65D51/241
摘要： The invention relates to a device for stopping a container (1) having a neck (12), said device comprising a stopper (51) and a cap (52) consisting of a plastic material and able to surround both the stopper (51) and the neck (12). The cap (52) comprises a ring (53) that can surround the stopper and the neck when mounted and is provided with means (537) for locking onto the neck, and a body (54) for handling the ring, provided with first means for transmitting a thrust force to the ring and second means (541) for activating means for locking the ring. The ring (53) is provided with a continuous outer peripheral collar (5311), and the handling body (54) is provided with at least one raised element (5431) designed to abut (E4) against the continuous outer peripheral collar (5311) when it activates the locking means (537).
摘要翻译：本发明涉及一种用于停止具有颈部（12）的容器（1）的装置，所述装置包括止动器（51）和由塑料材料组成并能够包围止动器（51）和颈部（12）。盖（52）包括环（53），其在安装时可围绕止动器和颈部，并且设置有用于锁定在颈部上的装置（537）和用于处理环的主体（54），其设置有第一装置用于向环传递推力和用于锁定环的致动装置的第二装置（541）。环（53）设置有连续的外周圈（5311），并且处理主体（54）设置有至少一个设计成抵靠（E4）抵靠连续的外周环（5311）的凸起元件（5431）当它启动锁定装置（537）时。

75. 发明授权

US08225949B2 Plug device for a container and container provided with one such device 有权
标题翻译：用于容器和容器的插头装置，其具有一个这样的装置
公开(公告)号：US08225949B2
公开(公告)日：2012-07-24
申请号：US12085325
申请日：2006-11-29
申请人： Antoine Aneas
发明人： Antoine Aneas
IPC分类号： B65D51/00
CPC分类号： B65D51/002 , A61J1/1406 , B65D51/241 , Y10S604/905 , Y10T29/53
摘要： The closure device (500) comprises a stopper (501) made of elastomer and a cover (502) suitable for covering both the neck (12) of a container and stopper (501) in place in said neck (12). The cover (502) is made of plastics material and comprises a ring (503) and a drive member (504). The ring (503) may surround the stopper (501) and the neck (12) in the mounted configuration, the ring being provided with locking means (503G) for locking on the neck (12). The drive member (504) may be mounted on the ring (503) in arbitrary angular orientation about a central axis (X503) of the ring. The drive member is provided with an annular edge (505D) suitable for being engaged between an outer skirt (503A) of the ring (503) and at least one tab (503G) forming locking means and extending radially towards the central axis (X503) of the ring from the skirt (503A).
摘要翻译：封闭装置（500）包括由弹性体制成的止动件（501）和适于将容器的颈部（12）和位于所述颈部（12）中的止动件（501））覆盖的盖（502）。盖（502）由塑料材料制成并且包括环（503）和驱动构件（504）。环（503）可以围绕安装结构的止动器（501）和颈部（12）围绕，环设置有用于锁定在颈部（12）上的锁定装置（503G）。驱动构件（504）可以围绕环的中心轴线（X503）以任意角度取向安装在环（503）上。驱动构件设置有适于接合在环（503）的外裙部（503A）和形成锁定装置并且朝向中心轴线（X503）径向延伸的至少一个突片（503G）的环形边缘（505D）的环（503A）。

76. 发明申请

US20100050575A1 DEVICE FOR STOPPING A CONTAINER, CONTAINER EQUIPPED WITH SUCH A DEVICE AND METHOD FOR CLOSING A BATCH OF SUCH CONTAINERS 有权
标题翻译：用于停止集装箱的装置，装有这种装置的集装箱和关闭这些集装箱的方法
公开(公告)号：US20100050575A1
公开(公告)日：2010-03-04
申请号：US12449302
申请日：2008-02-08
申请人： Antoine Aneas
发明人： Antoine Aneas
IPC分类号： B67B3/00 , B65B7/28 , B65D1/02
CPC分类号： B65D41/28 , B65D45/322 , B65D51/002 , B65D51/241
摘要： This device comprises an elastomer stopper (501) and a cap (502) suitable for covering both the neck (12) of a container and the stopper in position in this neck. The cap comprises a ring (503) provided with means (503G) for locking it to the neck and an operating member (504). The operating member (504) is fitted with at least one deformable part (506C) for transmitting a thrust load (f2) parallel to a central axis (X503) of the ring (503), between two portions (505, 506) of this member (504) or between an external material (301) and this member (504). The load transmitting part (506C) is deformable between a first configuration in which its length (L506) parallel to the central axis (X503) is a first value and a second configuration in which this parallel length is a second value that is less than the first value.
摘要翻译：该装置包括弹性体止动器（501）和适于覆盖容器的颈部（12）并且止动器在该颈部中适当位置的帽（502）。该盖包括设置有用于将其锁定到颈部的装置（503G）的环（503）和操作构件（504）。操作构件（504）装配有至少一个可变形部分（506C），用于传递平行于该环（503）的中心轴线（X503）的推力负载（f2），该推力载荷在该两个部分（505,506）之间构件（504）或外部材料（301）与该构件（504）之间。载荷传递部分（506C）可在其平行于中心轴线（X503）的长度（L506）为第一值的第一构造和第二构造之间变形，其中该平行长度为小于第一个价值。

77. 发明申请

US20050086830A1 Processing cap assembly for isolating contents of a container 审中-公开
标题翻译：用于隔离容器内容物的加工盖组件
公开(公告)号：US20050086830A1
公开(公告)日：2005-04-28
申请号：US10693371
申请日：2003-10-24
申请人： Kenneth Zukor , John DiMeo , Michael Wikol
发明人： Kenneth Zukor , John DiMeo , Michael Wikol
IPC分类号： B65D51/24 , F26B5/06
CPC分类号： F26B5/06 , B01L3/50825 , B01L2300/048 , B65D51/241
摘要： Improved cap assemblies which isolate materials in containers, e.g., bottles, vials, multi-vial trays, multi-well trays, etc., during processes while permitting vapor to pass into or out of the container, such as during freeze drying and the like, and facilitate subsequent closure of the container to cease such vapor passage (e.g., stoppering, etc.). The cap assembly optimizes containment of solute, prevents contamination, is easy to use and is readily compatible with validated industrial drying processes.
摘要翻译：改进的盖组件，其在过程中隔离容器中的材料，例如瓶，小瓶，多小瓶托盘，多孔托盘等，同时允许蒸汽进入或离开容器，例如在冷冻干燥等期间并且便于随后关闭容器以停止这种蒸汽通过（例如，塞住等）。盖组件优化了溶质的封闭，防止污染，易于使用，并且容易与验证的工业干燥过程相容。

78. 发明授权

US6070748A Break away overcap 失效
标题翻译：打破帽子
公开(公告)号：US6070748A
公开(公告)日：2000-06-06
申请号：US201637
申请日：1998-11-30
申请人： James R. Storar
发明人： James R. Storar
IPC分类号： B65D41/28 , B65D51/00 , B65D51/18 , B65D51/24 , B65D41/00
CPC分类号： B65D41/28 , B65D51/002 , B65D51/18 , B65D51/241 , B65D2251/0015 , B65D2251/009
摘要： A break away overcap (1) is used for maintaining a closure (6) in sealing engagement with the open end of a vial (2). The overcap (1) is molded from a fracturable plastic and is provided with a pair of spaced, parallel score lines or V-grooves (5) extending across the top wall (3) of the overcap (1) and downwardly of the cap skirt (4) to the lower edge thereof on each side of the cap. Thumb and finger engaging portions (4a) are provided at the lower edge of the skirt (4) adjacent the terminal ends of the score lines (5) so that by pushing inwardly on the thumb and finger engaging portions, (4a) the overcap (1) breaks into three pieces to thereby expose the closure (6) for insertion of a syringe needle therethrough into the vial for removal of the vial contents therefrom.
摘要翻译：脱离盖帽（1）用于保持与小瓶（2）的开口端密封接合的封闭件（6）。顶盖（1）由可破碎的塑料模制而成，并且设置有一对间隔开的平行的刻痕线或跨越顶盖（1）的顶壁（3）延伸的V形槽（5），并且帽盖裙部（4）到盖的每一侧的下边缘。拇指和手指接合部分（4a）设置在靠近刻痕线（5）的终端的裙部（4）的下边缘处，使得通过向内推动拇指和手指接合部分，（4a）顶盖（ 1）分成三块，从而露出用于将注射器针插入其中的封闭件（6）进入小瓶中以从中取出小瓶内容物。

79. 发明授权

US5957314A Crown caps for drug containers 失效
标题翻译：用于药物容器的冠盖
公开(公告)号：US5957314A
公开(公告)日：1999-09-28
申请号：US973423
申请日：1997-12-08
申请人： Hirotaka Nishida , Kouiti Yoshimi , Keiji Hamamoto
发明人： Hirotaka Nishida , Kouiti Yoshimi , Keiji Hamamoto
IPC分类号： B65D41/58 , B65D45/30 , B65D45/32 , B65D51/00 , B65D51/24 , B65D41/20 , B65D41/62
CPC分类号： B65D51/002 , B65D45/322 , B65D51/241
摘要： A rubber gasket is closely sealed by integrally connecting a removable close-fastening ring to a top board of a crown-like member to be fitted to a mouth portion in which a liquid drug is kept and pulling down the close-fastening ring to cover the outer periphery of the crown-like member.
摘要翻译： PCT No.PCT / JP96 / 02854 Sec。 371 1997年12月8日第 102（e）日期1997年12月8日PCT 1996年10月1日PCT PCT。 WO97 / 37902 PCT公开号 1997年10月16日1997年10月16日，橡胶垫片通过将可拆卸的紧固环整体连接到冠状构件的顶板上而紧密地密封，以将其装配到其中保持液体药物的口部，紧固环以覆盖冠状构件的外周。

80. 发明授权

US5819964A Lyophilization closure assembly for a medicament container for use during a lyophilization process 失效
标题翻译：用于在冻干过程中使用的药物容器的冻干闭合组件
公开(公告)号：US5819964A
公开(公告)日：1998-10-13
申请号：US825836
申请日：1997-04-04
申请人： Jean Pierre Grimard
发明人： Jean Pierre Grimard
IPC分类号： B65D51/16 , A61J1/05 , B65D51/00 , B65D51/18 , B65D51/24 , B65D41/58
CPC分类号： B65D51/002 , B65D51/241
摘要： A lyophilization closure assembly for a container or vial is disclosed. The lyophilization closure assembly is self-supporting with the container and may be employed with the container during a lyophilization process, eliminating the need for a separate crimping operation outside of the sterile environment in which lyophilization is conducted. The lyophilization closure assembly includes a body with a skirt disposed around the rim of the container. The skirt features one or more deflectable abutments and one or more deflectable latches positionable about the rim of the container, and defines one or more vapor passages. An elastomeric closure is retained within the body for sealing the open top of the medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. The body defines an opening over the elastomeric closure that delimits an access area on the top surface of the closure. A membrane is removably secured over the access area of the elastomeric closure and hermetically encloses the access area.
摘要翻译：公开了一种用于容器或小瓶的冻干封闭组件。冻干封闭组件与容器自支撑并且可以在冷冻干燥过程中与容器一起使用，从而不需要进行冷冻干燥的无菌环境之外的单独卷曲操作。冻干闭合组件包括具有设置在容器的边缘周围的裙部的主体。裙部具有一个或多个可偏转的邻接部以及可围绕容器的边缘定位的一个或多个可偏转的闩锁，并且限定一个或多个蒸气通道。弹性体封闭件保持在主体内，用于密封药物容器的开口顶部。弹性体闭合件具有用于密封容器的敞开顶部的塞子和背离容器开口顶部的顶表面。主体限定弹性封闭件上的开口，其限定封闭件顶表面上的通路区域。膜可移除地固定在弹性体封闭件的进入区域上并且密封地包围进入区域。

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