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    • 61. 发明授权
    • Capillary electrophoresis apparatus
    • 毛细管电泳仪
    • US6048444A
    • 2000-04-11
    • US979542
    • 1997-11-26
    • Satoshi TakahashiHideki KambaraTakashi Yamada
    • Satoshi TakahashiHideki KambaraTakashi Yamada
    • G01N27/447G01N27/26
    • G01N27/44782G01N27/44721
    • A capillary electrophoresis apparatus of the invention has: a plurality of capillaries which are filled with a migration medium and have first ends into which samples are injected and second ends in which components included in the samples are eluted; a sheath flow cell in which the second ends are arranged in a straight line at first predetermined intervals and are terminated and a sheath flow is formed; a buffer solution vessel for housing a buffer solution flowing in the sheath flow cell; a drain vessel housing the buffer solution flowed from the sheath flow cell; an optical system emitting laser light to a part near the second ends; and a fluorescent detection system for detecting fluorescent light generated from fluorophore labelling the components included in the sample eluted near the second ends by the emission of laser light, wherein the buffer solution flows from the lower part to the upper part of the sheath flow cell, thereby forming a sheath flow in the sheath flow cell.
    • 本发明的毛细管电泳装置具有:填充有迁移介质的多个毛细管,其具有注入样品的第一端和样品中包含的成分被洗脱的第二端; 鞘流池,其中第二端以第一预定间隔以直线布置并且终止并形成鞘流; 用于容纳在鞘流池中流动的缓冲溶液的缓冲溶液容器; 容纳从鞘流池流出的缓冲溶液的排水管; 将激光发射到靠近第二端的部分的光学系统; 以及荧光检测系统,用于检测由荧光团产生的荧光,其中通过发射激光来标记在第二端附近洗脱的样品中包含的成分,其中缓冲溶液从鞘流动池的下部流向上部, 从而在鞘流动池中形成鞘流。
    • 65. 发明授权
    • Oscillator circuit and delay circuit
    • 振荡电路和延迟电路
    • US5912591A
    • 1999-06-15
    • US24298
    • 1998-02-17
    • Takashi Yamada
    • Takashi Yamada
    • H01L27/04H01L21/822H01L21/8234H01L21/8242H01L27/088H01L27/108H01L29/786H03K3/0231H03K3/03H03K3/354H03B5/24
    • H03K3/354H03K3/0231H03K3/03H03K3/0322H03K2217/0018
    • The present invention provides a novel circuitry comprising a series connection of a plurality of invertor gates, each of which has field effect transistors, wherein at least one of the field effect transistors has a back bias control terminal; and a various bias voltage generator being capable of generating at least one bias voltage and also capable of varying the at least one bias voltage individually, the various bias voltage generator being also electrically connected to the back bias control terminal of the at least one of the field effect transistors for applying the at least one bias voltage to the back bias control terminal so that the various bias voltage generator is operated to individually vary the at least one bias voltage thereby to individually vary a threshold voltage of the at least one of the field effect transistors.
    • 本发明提供了一种新颖的电路,其包括多个反相器门的串联连接,每个反相器门均具有场效应晶体管,其中至少一个场效应晶体管具有背偏置控制端; 以及各种偏置电压发生器,其能够产生至少一个偏置电压并且还能够单独地改变所述至少一个偏置电压,所述各种偏置电压发生器还电连接到所述至少一个偏置电压的反偏压控制端子 用于将至少一个偏置电压施加到背偏压控制端子的场效应晶体管,使得各种偏置电压发生器被操作以单独地改变至少一个偏置电压,从而单独地改变场中的至少一个的阈值电压 效应晶体管。
    • 69. 发明授权
    • Reaction vessel for conducting an immunological assay
    • 用于进行免疫学测定的反应容器,具有用于将样品移动到反应区的毛细管沟槽和用于使液体吸收构件与反应容器物理接触以除去液体的可变形支撑构件
    • US5399316A
    • 1995-03-21
    • US25833
    • 1993-03-03
    • Takashi Yamada
    • Takashi Yamada
    • B01L3/00B01L99/00G01N21/76G01N33/53G01N33/543G01N33/546G01N33/552
    • B01L3/50273G01N21/76G01N33/5304G01N33/54366B01L2300/069B01L2300/0825B01L2400/0406B01L2400/0633B01L2400/065G01N21/6428Y10S435/805Y10S435/97Y10S436/805Y10S436/808Y10S436/81
    • A sample solution is dripped on an injection region with a pipette. The sample solution immediately spreads in a reaction region by a capillary phenomenon. The sample solution is left for a predetermined period of time to bind a biological associated material in the sample solution with a specific affinity material bound on the inner surface of the reaction region. After the reaction, the outer surface portion of a support member is pushed against a reaction vessel main body to deform the support member, thereby bringing the sample solution into contact with a water absorbent member at a removal region. The sample solution is absorbed by the water absorbent member and is removed from the reaction region. A cleaning solution is dripped on the injection region in an appropriate amount to perform B/F separation and is allowed to spread in the reaction region. The cleaning solution is absorbed and removed by the water absorbent member. The biological associated material bound to the reaction region is assayed.
    • 用移液管将样品溶液滴在注射区域上。 样品溶液立即通过毛细管现象扩散在反应区域。 将样品溶液放置一段预定的时间以将样品溶液中的生物相关材料与结合在反应区域的内表面上的特异性亲和材料结合。 反应结束后,将支撑部件的外表面部分压靠在反应容器主体上,使支撑部件变形,从而使样品溶液与去除区域的吸水部件接触。 样品溶液被吸水部件吸收,从反应区域除去。 将清洗溶液以适当的量滴在注射区域上以进行B / F分离,并使其在反应区域中扩散。 清洗液被吸水部件吸收除去。 测定与反应区域结合的生物相关物质。