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61. 发明授权

US06878161B2 Stent graft loading and deployment device and method 失效
标题翻译：支架移植装载和部署装置及方法
公开(公告)号：US06878161B2
公开(公告)日：2005-04-12
申请号：US10133154
申请日：2002-04-25
申请人： Jay A. Lenker
发明人： Jay A. Lenker
IPC分类号： A61F2/90 , A61F2/06
CPC分类号： A61F2/90 , A61F2/07 , A61F2/844 , A61F2/89 , A61F2002/075 , A61F2002/9511 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067
摘要： An endoluminal prosthesis includes a tubular graft, an expandable annular support structure and a restraining mechanism restraining the prosthesis in a collapsed configuration in which the annular support structure is compressed to a low profile. The restraining mechanism holds the annular support structures in the collapsed configuration until the prosthesis is positioned for deployment. The restraining mechanism is then released to allow the annular support structures to expand into conforming engagement with the inner wall of a lumen in which the prosthesis is to be deployed. A feature according to the invention provides a balloon catheter onto which the prosthesis is loaded for deployment where the balloon is expanded to provide a radial force to release the restraining mechanism. Another feature provides for a restraining member that breaks upon application of the radial force to release the annular support structure from its constrained configuration. Another feature of the invention provides for independent and/or sequential release of the annular support members. Various types of annular support members attached to tubular grafts in a variety of manners may be used in accordance with the invention. The invention may be used in tubular grafts for endoluminal placement within a body lumen, including blood vessels, and for the treatment of abdominal and other aneurysms.
摘要翻译：腔内假体包括管状移植物，可扩张的环状支撑结构和限制假体处于折叠构造的约束机构，其中环形支撑结构被压缩至低轮廓。限制机构将环形支撑结构保持在折叠构型中，直到假体被定位用于展开。然后释放约束机构以允许环形支撑结构膨胀成与其中将要展开假体的内腔的内壁相一致的接合。根据本发明的特征提供了一种气囊导管，其上装载假体用于展开，其中气囊被扩张以提供径向力以释放约束机构。另一个特征提供了限制构件，其在施加径向力时破裂，以将环形支撑结构从其约束构型释放。本发明的另一个特征提供了环形支撑构件的独立和/或顺序释放。根据本发明，可以使用以各种方式附接到管状移植物上的各种类型的环形支撑构件。本发明可用于管状移植物，用于腔内放置在体腔内，包括血管，以及用于治疗腹部和其他动脉瘤。

62. 发明授权

US06821263B2 Method and apparatus for venous drainage and retrograde coronary perfusion 失效
标题翻译：静脉引流和逆行冠状动脉灌注的方法和装置
公开(公告)号：US06821263B2
公开(公告)日：2004-11-23
申请号：US10759310
申请日：2004-01-16
申请人： Jay A. Lenker , Eugene M. Breznock
发明人： Jay A. Lenker , Eugene M. Breznock
IPC分类号： A61M3700
CPC分类号： A61M1/3653 , A61M1/3613 , A61M1/3656 , A61M1/3659 , A61M1/3664 , A61M2025/1013 , A61M2202/047
摘要： A system is disclosed for cannulating the vena cava of a patient during cardiopulmonary bypass procedures. Such cannulation is necessary for drainage of venous blood from the patient so that it may be oxygenated and pumped back to the patient to perfuse tissues during cardiac surgery and, more specifically, during periods of ischemic cardiac arrest or dysfunction. The device of the present invention not only provides venous drainage for cardiopulmonary bypass, but also performs the function of routing cardioplegic solution through the heart in the retrograde direction. Such cardioplegia provides protection to the heart during periods of ischemic cardiac arrest. This invention replaces a plurality of cannulae currently used for open-heart surgery, thus simplifying the surgical field and improving visibility of the heart. The device allows for the delivery of retrograde cardioplegia to the coronary circulation of both the right and the left side of the heart. The device further includes protection mechanisms to prevent overinflation or excessive pressurization of the right atrium during retrograde delivery of cardioplegia solution.
摘要翻译：公开了一种用于在体外循环手术期间插入患者的腔静脉的系统。这种插管对于从患者排出静脉血液是必需的，使得其可以被氧合并泵送回患者以在心脏手术期间，更具体地，在缺血性心脏骤停或功能障碍期间灌注组织。本发明的装置不仅提供用于体外循环的静脉引流，而且还执行沿逆行方向通过心脏路由心脏停搏溶液的功能。这种心脏停跳在缺血性心脏骤停期间为心脏提供保护。本发明代替目前用于开心手术的多个套管，从而简化了手术领域并提高了心脏的可见度。该装置允许将逆行心麻痹递送到心脏右侧和左侧的冠状动脉循环。该装置还包括用于在逆行递送心麻痹液期间防止右心房过度充气或过度加压的保护机制。

63. 发明授权

US06200280B1 Cardiac massage apparatus and method 失效
公开(公告)号：US06200280B1
公开(公告)日：2001-03-13
申请号：US09087665
申请日：1998-05-29
申请人： Rodney A. Brenneman , Jay A. Lenker
发明人： Rodney A. Brenneman , Jay A. Lenker
IPC分类号： A61H3100
CPC分类号： A61H31/007 , A61H2031/001 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/1086 , A61M1/12
摘要： A device for performing minimally invasive closed chest heart massage comprises a support having a plurality of curved, deployable struts, optionally carrying a sheet or inflatable bladder for engaging the pericardium. The struts are delivered to the space between the pericardium and the posterior rib cage in a radially collapsed configuration and deployed radially outwardly with minimum advancement in the axial direction.

64. 发明授权

US5860923A Lesion measurement catheter and method 失效
标题翻译：病变测量导管及方法
公开(公告)号：US5860923A
公开(公告)日：1999-01-19
申请号：US757413
申请日：1996-11-27
申请人： Jay A. Lenker , Rodney A. White , Richard Murphy , Steve Kim
发明人： Jay A. Lenker , Rodney A. White , Richard Murphy , Steve Kim
IPC分类号： A61B5/00 , A61B5/107 , A61B6/12 , A61B8/00 , A61B19/00 , A61F2/00 , A61F2/06 , A61F2/84 , A61M25/00 , A61B6/00
CPC分类号： A61B5/02014 , A61B5/1076 , A61F2/958 , A61M25/00 , A61B2090/061 , A61B90/39 , A61F2/07 , A61F2250/0098 , A61M2025/0008
摘要： The invention provides apparatus for determining physiological characteristics of body lumens, such as the length of a blood vessel. A catheter allows measurements of the distance between a first target location and a second target location within a lumen by aligning a first marker on a first elongate member disposed within a lumen with the first target location. A second marker on a second elongate member disposed within the lumen is aligned with the second target location. The distance between the first and second markers is then directly measured from spaced-apart calibration marks along the second member, and the measured distance corresponds to the distance between the first and second target locations.
摘要翻译：本发明提供了用于确定体腔的生理特征的装置，例如血管的长度。导管允许通过将设置在内腔内的第一细长构件与第一目标位置对准第一标记，来测量第一目标位置和内腔内的第二目标位置之间的距离。设置在内腔内的第二细长构件上的第二标记与第二目标位置对准。然后从间隔开的校准标记沿着第二构件直接测量第一和第二标记之间的距离，并且所测量的距离对应于第一和第二目标位置之间的距离。

65. 发明授权

US5800520A Tubular endoluminar prosthesis having oblique ends 失效
标题翻译：具有斜端的管状内膜假体
公开(公告)号：US5800520A
公开(公告)日：1998-09-01
申请号：US744130
申请日：1996-11-05
申请人： Thomas J. Fogarty , Jay A. Lenker
发明人： Thomas J. Fogarty , Jay A. Lenker
IPC分类号： A61F2/06 , A61F2/90
CPC分类号： A61F2/07 , A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054
摘要： An intraluminar prosthesis includes a tubular member having at least one end which is at an oblique angle to the lumen. The prosthesis is inserted into a body lumen, such as a blood vessel, while compressed. The prosthesis is expanded within the lumen, and the oblique end of the prosthesis contacts the lumen at an oblique angle. This oblique angle reduces the stenotic effect of hyperplasia which generally occurs at the ends of intraluminal prostheses.
摘要翻译：内膜假体包括具有与内腔成倾斜角的至少一端的管状构件。假体被压入身体腔内，如血管。假体在内腔内扩张，并且假体的倾斜端以倾斜的角度接触内腔。这种倾斜角度减少了通常发生在腔内假体末端的增生的狭窄效应。

66. 发明授权

US5527336A Flow obstruction treatment method 失效
标题翻译：流阻治疗方法
公开(公告)号：US5527336A
公开(公告)日：1996-06-18
申请号：US398049
申请日：1995-03-02
申请人： Robert F. Rosenbluth , Jay A. Lenker , George R. Greene , Barry M. Calvarese
发明人： Robert F. Rosenbluth , Jay A. Lenker , George R. Greene , Barry M. Calvarese
IPC分类号： A61F2/00 , A61F2/06 , A61F2/84 , A61F2/90 , A61M25/10 , A61M29/02 , A61M29/00
CPC分类号： A61F2/958 , A61M25/1011 , A61M29/02 , A61F2002/30187 , A61F2002/9583 , A61F2230/0034 , A61M2025/0004 , A61M2025/1072
摘要： Disclosed is an apparatus and method for the treatment of the symptoms of obstructive prostatism. The apparatus comprises an expandable dilation catheter and preferably an axially elongate sheath, adapted for transurethral insertion via the external opening of the urethra. The sheath is ellipsoid in cross-section, and provides an initial path through which the catheter and a standard cystoscope lens is guided. The dilation catheter or the sheath are provided with a non-radiological locating means for positioning the dilation portion of the catheter with respect to an anatomical landmark. Once the catheter has been properly positioned with respect to both the bladder neck and the sphincter, the dilation balloon may be inflated to force open the affected prostatic urethra and eliminate the obstruction.
摘要翻译：公开了一种治疗阻塞性前列腺症症状的装置和方法。该装置包括可膨胀的扩张导管，优选地是轴向细长的护套，适于经由尿道的外部开口经尿道插入。护套是椭圆形的横截面，并且提供了导管和标准的膀胱镜镜片被引导通过的初始路径。扩张导管或护套设置有非放射性定位装置，用于相对于解剖学标记定位导管的扩张部分。一旦导管已经相对于膀胱颈和括约肌适当地定位，则膨胀气球可以被充气以迫使打开受影响的前列腺尿道并消除阻塞。

67. 发明授权

US5160341A Resorbable urethral stent and apparatus for its insertion 失效
标题翻译：可再吸收的尿道支架及其插入装置
公开(公告)号：US5160341A
公开(公告)日：1992-11-03
申请号：US610543
申请日：1990-11-08
申请人： Rodney A. Brenneman , Jay A. Lenker
发明人： Rodney A. Brenneman , Jay A. Lenker
IPC分类号： A61F2/02 , A61F2/04 , A61F2/88
CPC分类号： A61F2/962 , A61F2/88 , A61F2002/047 , A61F2002/9517 , A61F2210/0004
摘要： A resorbable stent, particularly adapted for implantation in the penile urethra, comprises a helical coil formed from a filament of a biocompatible, biodegradable material that is resiliently deformable. The stent is compressible from a first diameter to a smaller second diameter, and restores itself substantially to its first diameter by its own resiliency when the compressing force is removed. Polymers of polylactic acid and polyglycolic acid are preferred materials. A device for inserting the stent has a first embodiment that includes a retractable sheath surrounding a rotatable rod journaled in a stationary bushing. The stent is mounted on the rod and the bushing so that relative rotation of the rod and bushing compresses the stent by coiling it more tightly. The sheath is inserted into the urethra with the stent compressed inside of it, and the retracted. The rod and bushing are then relatively rotated so as to uncoil the stent, which is restored to its first diameter. A shearing sleeve is actuated to detach the stent from the rod and the bushing. A second embodiment includes a plunger on which the stent is detachably mounted. The plunger is inserted through the sheath, thereby compressing the stent. When the stent is discharged through the distal end of the sheath into the urethra, the stent resiliently restores itself to its first diameter.
摘要翻译：特别适于植入阴茎尿道的可再吸收支架包括由可弹性变形的生物相容性可生物降解材料的细丝形成的螺旋线圈。支架可以从第一直径压缩到较小的第二直径，并且当压缩力被去除时，其自身基本上恢复到其第一直径。聚乳酸和聚乙醇酸的聚合物是优选的材料。用于插入支架的装置具有第一实施例，其包括围绕在固定衬套中轴颈的可旋转杆的可缩回护套。支架安装在杆和衬套上，使得杆和衬套的相对旋转通过更紧密地卷绕来压缩支架。将护套插入尿道，将支架压缩在其内部并缩回。然后将杆和衬套相对地旋转，以便展开恢复到其第一直径的支架。致动一个剪切套筒将支架从杆和衬套上拆下。第二实施例包括柱塞，支架可拆卸地安装在柱塞上。柱塞通过护套插入，从而压缩支架。当支架通过护套的远端排出到尿道中时，支架弹性恢复其第一直径。

68. 发明授权

US4441216A Tissue heart valve and stent 失效
标题翻译：组织心脏瓣膜和支架
公开(公告)号：US4441216A
公开(公告)日：1984-04-10
申请号：US327081
申请日：1981-12-03
申请人： Marian I. Ionescu , Jay A. Lenker , Robert F. Rosenbluth
发明人： Marian I. Ionescu , Jay A. Lenker , Robert F. Rosenbluth
IPC分类号： A61F2/24 , A61F1/22
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0075 , Y10S623/90
摘要： An improved stent for prosthetic tissue heart valves having upright legs which have radiused upper tips which are approximately one-half the width of prior art stent legs is disclosed. These narrow tipped stent legs reduce stress induced in the leaflets by curvature of the leaflets around the tips of the stent legs in the closed position, extending the service life of the valve. Tabs are added to the tips of the stent legs to add structural strength. These tabs can be tapered or straight but their bottom portions must be narrower than the stent leg. The tabs have a plurality of holes in them through which coaptation stitches are passed. The coaptation stitch can be two separate stitches, one in a first plane and one in a second plane at 90.degree. to the first plane, or, in the preferred embodiment, a single figure eight stitch passing through the holes in the tab in a plane coincident with the long axis of the stent leg.

69. 发明申请

US20150011925A1 METHOD AND DEVICE FOR TEMPORARY EMERGENCY VESSEL ANASTOMOSES 审中-公开
标题翻译：用于临时应急航行器的方法和装置
公开(公告)号：US20150011925A1
公开(公告)日：2015-01-08
申请号：US13936379
申请日：2013-07-08
申请人： Robert F. Buckman, JR. , Jay A. Lenker , Donald J. Kolehmainen
发明人： Robert F. Buckman, JR. , Jay A. Lenker , Donald J. Kolehmainen
IPC分类号： A61B17/11 , A61M25/00
CPC分类号： A61B17/11 , A61B17/12 , A61B17/122 , A61B2017/1107 , A61B2017/1132 , A61B2017/12004 , A61B2090/0807
摘要： A device and method for achieving hemostasis and leakage control in vascular structures and other body ducts or vessels in an emergency room or trauma situation. The device has at least one shunt that contains an obturator on an end of the shunt. The shunt is inserted into a damaged vessel or lumen for sealing the leak or hemorrhage. Two shunts that both contain obturators on one of their ends can be inserted into two different vessels or lumens when the vessel or lumen has been severed. The obturators allow for the improved ease of insertion into the vessel or lumen. The two shunts are then releasably attached to restore fluid communication through the vessel or lumen. The shunt is placed temporarily within the patient and then removed when definitive repair can be achieved by a qualified physician.
摘要翻译：用于在急诊室或创伤情况下在血管结构和其他身体导管或血管中实现止血和泄漏控制的装置和方法。该装置具有至少一个在分路端部包含闭孔器的分路器。分流器插入损伤的血管或腔内以密封泄漏或出血。当血管或内腔已被切断时，两个分流器都可以插入到两个不同的血管或腔内。闭孔器允许改进容易插入血管或内腔。然后将两个分流器可释放地连接以恢复通过容器或内腔的流体连通。分流器临时放置在患者体内，然后在由合格医师进行确定性修复时取出。

70. 发明授权

US08641777B2 Embolic implant and method of use 有权
标题翻译：栓塞植入物和使用方法
公开(公告)号：US08641777B2
公开(公告)日：2014-02-04
申请号：US13483962
申请日：2012-05-30
申请人： Brian Michael Strauss , Jeffrey J. Valko , Jay A. Lenker , Robert A. Pecor , Peter Barker , Maricruz Castaneda
发明人： Brian Michael Strauss , Jeffrey J. Valko , Jay A. Lenker , Robert A. Pecor , Peter Barker , Maricruz Castaneda
IPC分类号： A61F2/02
CPC分类号： A61B17/12172 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00526 , A61B2017/00539 , A61B2017/00544 , A61B2017/00557 , A61B2017/00867 , A61B2017/12054 , A61B2017/12063 , A61B2017/12068 , A61B2017/12077 , A61B2017/12081 , A61B2017/12086 , A61B2017/12095 , A61F2/01 , A61F2/91 , A61F2002/823 , A61F2220/0058 , A61F2230/0071 , A61F2230/0076 , A61L31/022 , A61L31/10 , A61L31/146 , A61L2400/04 , A61L2400/14 , A61L2400/16 , A61L2420/04 , A61L2430/36 , C08L27/18
摘要： A parent artery occlusion (PAO) device which provides for immediate occlusion of a cerebral artery to isolate a defect. The PAO device includes a self-expanding wire-frame prolate structure which is partially covered with an ePTFE membrane.
摘要翻译：父母动脉闭塞（PAO）装置，其提供立即闭塞大脑动脉以分离缺陷。 PAO装置包括部分被ePTFE膜覆盖的自膨胀线框扁长结构。

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