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    • 63. 发明申请
    • METHOD OF MANUFACTURING HOLLOW MICRONEEDLE STRUCTURES
    • 制造中空微结构的方法
    • US20110011827A1
    • 2011-01-20
    • US12621594
    • 2009-11-19
    • Dae Sik LEEHyun Woo SONGMoon Youn JUNGSeon Hee PARK
    • Dae Sik LEEHyun Woo SONGMoon Youn JUNGSeon Hee PARK
    • B44C1/22
    • A61M37/0015A61M2037/0023A61M2037/003A61M2037/0046A61M2037/0053B29C33/3842B29L2031/7544B29L2031/756B81B2201/055B81C1/00111
    • Provided is a method of manufacturing a hollow microneedle structure. The method includes forming an injection mold having a through hole, filling the injection mold with a photoresist formed of a viscous material, and extruding the photoresist from the injection mold through the through hole, solidifying the extruded photoresist to form a needle-type photoresist structure, forming a seed layer on the surface of the photoresist structure, forming a metal plated layer on the seed layer, inclining an end tip of the photoresist structure having the metal plated layer, and removing the photoresist from the metal plated layer to form a hollow. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. The hollow microneedle structure can be combined with an apparatus for detecting a biomaterial or injecting cosmetic substances or medicines, and variously applied.
    • 提供一种制造中空微针结构的方法。 该方法包括形成具有通孔的注射模具,用由粘性材料形成的光致抗蚀剂填充注射模具,并且通过通孔从注射模具中挤出光致抗蚀剂,固化挤出的光致抗蚀剂以形成针型光致抗蚀剂结构 在光致抗蚀剂结构的表面上形成种子层,在种子层上形成金属镀层,使具有金属镀层的光致抗蚀剂结构的末端倾斜,从金属镀层除去光致抗蚀剂,形成中空 。 因此,可以制造中空微针结构以具有使疼痛最小化的直径,长度,硬度和倾斜角度。 中空微针结构可以与用于检测生物材料或注射化妆品物质或药物的装置组合,并进行各种应用。
    • 66. 发明申请
    • METHOD OF CONTROLLING FLUID FLOW IN MICROFLUIDIC DEVICE AND MICROFLUIDIC ANALYSIS APPARATUS
    • 微流控器件流体流量控制方法及微流控分析仪
    • US20100159600A1
    • 2010-06-24
    • US12581106
    • 2009-10-16
    • Dong-Ho SHINMinsuk JEONGKyu Ho SONGHyeYoon KIMJuHyun JEONMoon Youn JUNGSeon Hee PARK
    • Dong-Ho SHINMinsuk JEONGKyu Ho SONGHyeYoon KIMJuHyun JEONMoon Youn JUNGSeon Hee PARK
    • G01N35/10G01N33/00
    • B01L3/50273B01L9/527B01L2400/0457G01N35/08Y10T436/11
    • Provided are methods of controlling a fluid flow in a microfluidic device and a microfluidic analysis apparatus. According to the method, an inclination of the microfluidic device with respect to a horizontal direction can be adjusted to simply and accurately control a fluid flow in the microfluidic device. Thus, a fluid conveyance can be completely controlled, and an inspection can be performed using only a small amount of sample. In addition, the method of controlling the fluid flow in the microfluidic device can be manually performed by a user. Thus, since a power is not required, the method of controlling the fluid flow in the microfluidic device can be economical and simple. The microfluidic analysis apparatus includes an inclination operation unit for causing an inclination change of a receiving part of the microfluidic device with respect to a horizontal plane and an inclination control part for controlling an operation of the inclination operation unit to simply and accurately control the fluid flow, thereby to accurately analyze the fluid.
    • 提供了控制微流体装置和微流体分析装置中的流体流动的方法。 根据该方法,可以调节微流体装置相对于水平方向的倾斜度以简单且精确地控制微流体装置中的流体流动。 因此,可以完全控制流体输送,并且可以仅使用少量的样品进行检查。 此外,控制微流体装置中的流体流动的方法可以由用户手动执行。 因此,由于不需要动力,所以控制微流体装置中的流体流动的方法可以是经济和简单的。 微流体分析装置包括倾斜操作单元,用于使微流体装置的接收部相对于水平面倾斜变化,以及用于控制倾斜操作单元的操作的倾斜控制部,以简单且精确地控制流体流动 ,从而准确地分析流体。