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51. 发明申请

US20010027294A1 Fluid delivery apparatus with flow indicator and vial fill 失效
公开(公告)号：US20010027294A1
公开(公告)日：2001-10-04
申请号：US09767665
申请日：2001-01-22
发明人： Marshall S. Kriesell , Steven M. Arnold , James Garrison , Farhad Kazemzadeh , William Kuester , Rolf Hogan
IPC分类号： A61M037/00 , A61M001/00
CPC分类号： A61M5/152 , A61M5/141 , A61M5/16877 , A61M2205/583 , A61M2205/585
摘要： An apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus is of a compact, low profile, laminate construction and includes an elastic distendable membrane, chamber having a fluid outlet. Disposed within the fluid chamber is a thin fluid permeable member which precisely controls the rate of fluid flow through the fluid outlet. The apparatus also includes a highly novel fluid flow indicator that provides a readily discernible visible indication of fluid flow through the apparatus. Additionally, the apparatus includes a fill assembly comprising a prefilled vial that can be used to fill the fluid reservoir of the device with a selected medicinal fluid.

52. 发明授权

US6159180A Fluid delivery apparatus with flow indicator and vial fill 失效
公开(公告)号：US6159180A
公开(公告)日：2000-12-12
申请号：US139605
申请日：1998-08-24
申请人： Marshall S. Kriesel , Steven M. Arnold , James Garrison , Farhad Kazemzadeh
发明人： Marshall S. Kriesel , Steven M. Arnold , James Garrison , Farhad Kazemzadeh
IPC分类号： A61M5/14 , A61M5/152 , A61M5/168 , A61M37/00
CPC分类号： A61M5/141 , A61M5/152 , A61M2205/583 , A61M2205/585 , A61M5/16877 , Y10S128/12
摘要： An apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus is of a compact, low profile, laminate construction and includes an elastic distendable membrane, chamber having a fluid outlet. Disposed within the fluid chamber is a thin fluid permeable member which precisely controls the rate of fluid flow through the fluid outlet. The apparatus also includes a highly novel fluid flow indicator that provides a readily discernible visible indication of fluid flow through the apparatus. Additionally, the apparatus includes a fill assembly comprising a prefilled vial that can be used to fill the fluid reservoir of the device with a selected medicinal fluid.

53. 发明授权

US06086561A Fluid delivery apparatus with reservoir fill assembly 失效
标题翻译：流体输送装置，具有储液器填充组件
公开(公告)号：US06086561A
公开(公告)日：2000-07-11
申请号：US250036
申请日：1999-02-12
申请人： Marshall S. Kriesel , Jmaes M. Garrison , Steven Arnold , Farhad Kazemzadeh
发明人： Marshall S. Kriesel , Jmaes M. Garrison , Steven Arnold , Farhad Kazemzadeh
IPC分类号： A61M5/152 , A61M5/168 , A61M37/00 , B01L3/00 , G01F1/38 , G01L7/00 , G01L7/02 , G01P13/00
CPC分类号： A61M5/16854 , A61M5/152 , A61M5/16886 , G01P1/07 , G01P13/0026 , G01P13/0066 , A61M2205/583 , A61M2205/585 , A61M2209/045
摘要： An apparatus for delivering fluids at a precisely controlled rate which includes a fluid dispensing component having a fluid reservoir for containing the fluids to be delivered and a reservoir fill component which can be removably interconnected with the fluid dispensing component. The reservoir fill assembly is uniquely designed to accept a vial component of conventional construction which is factory filled with the medicinal fluid to be delivered to the patient. The dispenser component embodies a highly novel fluid flow indicator that provides a readily discernible visual indication of fluid flow status through the device.
摘要翻译：一种用于以精确控制的速率输送流体的装置，其包括具有用于容纳待输送流体的流体储存器的流体分配部件和可与流体分配部件可拆卸地互连的储存器填充部件。储存器填充组件被独特地设计成接受常规结构的小瓶部件，该小瓶部件在工厂中填充有要输送给患者的药液。分配器部件体现了高度新颖的流体流量指示器，其提供通过装置的流体流动状态的容易辨别的视觉指示。

54. 发明授权

US5840071A Fluid delivery apparatus with flow indicator and vial fill 失效
公开(公告)号：US5840071A
公开(公告)日：1998-11-24
申请号：US768663
申请日：1996-12-18
申请人： Marshall S. Kriesel , Steven M. Arnold , James Garrison , Farhad Kazemzadeh
发明人： Marshall S. Kriesel , Steven M. Arnold , James Garrison , Farhad Kazemzadeh
IPC分类号： A61M5/14 , A61M5/152 , A61M5/168 , A61M37/00
CPC分类号： A61M5/141 , A61M5/152 , A61M2205/583 , A61M2205/585 , A61M5/16877 , Y10S128/12
摘要： An apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus is of a compact, low profile, laminate construction and includes an elastic distendable membrane, chamber having a fluid outlet. Disposed within the fluid chamber is a thin fluid permeable member which precisely controls the rate of fluid flow through the fluid outlet. The apparatus also includes a highly novel fluid flow indicator that provides a readily discernible visible indication of fluid flow through the apparatus. Additionally, the apparatus includes a fill assembly comprising a prefilled vial that can be used to fill the fluid reservoir of the device with a selected medicinal fluid.

55. 发明授权

US5584815A Multi-cartridge medication injection device 失效
标题翻译：多药盒注射装置
公开(公告)号：US5584815A
公开(公告)日：1996-12-17
申请号：US424660
申请日：1995-04-19
申请人： Gerhard E. F. Pawelka , Christopher J. Stringer , Matthew Marsh , David L. Karshmer , Christopher O. Lada , Stephen J. Schoenberg
发明人： Gerhard E. F. Pawelka , Christopher J. Stringer , Matthew Marsh , David L. Karshmer , Christopher O. Lada , Stephen J. Schoenberg
IPC分类号： A61M5/142 , A61M5/178 , A61M5/19 , A61M5/24 , A61M5/315 , A61M5/00
CPC分类号： A61M5/31581 , A61M5/19 , A61M5/24 , A61M5/2448 , A61M5/31553 , A61M2005/2407 , A61M2005/2488 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/585 , A61M5/2466 , A61M5/31535 , A61M5/31541 , A61M5/31543 , A61M5/31561 , A61M5/31563 , A61M5/3157
摘要： A multi-cartridge dispenser for delivering two liquid medications through a single needle. The dispenser includes independent dual channel metering mechanism, dual channel drive mechanisms, and dual channel lock and pullback mechanisms. The wing must be in its "up" position for metering to take place. The wing reciprocatingly moves a driver between a pre-injection position and a post-injection position to reciprocatingly advance the leadscrews upon an injection stroke. The dosage indicator automatically rotates to its initial zero position upon the injection stroke. The lock and pullback mechanism automatically prevents rotation of the leadscrew upon metering and injection. It also locks out the cartridge retainers so that the retainers can be removed from the housing only while the wing is in its "down" position. The pullback sleeve unloads a pullback key during a cartridge change in order to enable the leadscrew to be spun freely back to its home position.
摘要翻译：用于通过单针提供两种液体药物的多盒式分配器。分配器包括独立的双通道计量机构，双通道驱动机构和双通道锁定和回拉机构。机翼必须处于“向上”位置，才能进行计量。机翼在预喷射位置和后喷射位置之间使驾驶员往复运动，以便在喷射冲程时使丝杆往复运动。剂量指示剂在注射冲程时自动旋转到其初始的零位置。锁定和拉回机构在计量和注射时自动防止丝杠旋转。它还锁定墨盒保持器，以便只有当机翼处于“向下”位置时，保持器才能从外壳中取出。拉回套筒在墨盒更换期间卸载回拉键，以使丝杠自由旋转回到其原始位置。

56. 发明授权

US5468233A Hypodermic dosage measuring device 失效
标题翻译：皮下剂量测量装置
公开(公告)号：US5468233A
公开(公告)日：1995-11-21
申请号：US161461
申请日：1993-12-06
申请人： Steven Schraga
发明人： Steven Schraga
IPC分类号： A61J1/00 , A61J1/20 , A61M5/178 , A61M5/315 , A61M5/00
CPC分类号： A61M5/1782 , A61J1/201 , A61J1/2051 , A61J1/2055 , A61J1/2096 , A61M2005/3152 , A61M2205/583 , A61M2205/585
摘要： A hypodermic dosage measuring device to be utilized with a hypodermic syringe and a conventional drug vial, the dosage measuring device including a vial holding portion adapted to hold a head of the drug vial non-slidably therein, a syringe holding portion adapted to hold the syringe in a non-slidable position with a needle of the syringe disposed within the drug vial, and a dose adjustment portion, the dose adjustment portion including an elongate plunger holder and gear element, the plunger holder and gear element each including a plurality of teeth thereon such that movement of the gear element results in an elongate track segment of the plunger holder sliding in a longitudinal direction parallel to a length of the syringe. The plunger holder further including a plunger engagement segment extending perpendicularly from a proximal end of the track segment, the plunger engagement section being adapted to engage a plunger of the syringe such that longitudinal movement of the plunger holder results in corresponding longitudinal movement of the plunger of the syringe relative to a dosage holding area of the syringe, the precise dosage measure being indicated by dosage indicating indicia on the dose adjustment portion.
摘要翻译：一种用于皮下注射器和常规药物小瓶的皮下注射剂量测量装置，所述剂量测量装置包括适于将药物瓶的头部不可滑动地保持在其中的小瓶保持部分，适于保持注射器的注射器保持部分在具有注射器针头的不可滑动的位置处设置在药瓶中，以及剂量调节部分，剂量调节部分包括细长柱塞保持器和齿轮元件，柱塞保持器和齿轮元件各自包括多个齿使得齿轮元件的移动导致柱塞保持器的细长轨道段在与注射器的长度平行的纵向方向上滑动。所述柱塞保持器还包括从所述轨道段的近端垂直延伸的柱塞接合段，所述柱塞接合部分适于接合所述注射器的柱塞，使得所述柱塞保持器的纵向运动导致柱塞的柱塞的相应纵向运动注射器相对于注射器的剂量保持区域，精确的剂量测量由剂量指示剂量调整部分上的指示指示。

57. 发明授权

US5377725A Visual magnification apparatus for a syringe 失效
标题翻译：用于注射器的视觉放大装置
公开(公告)号：US5377725A
公开(公告)日：1995-01-03
申请号：US120917
申请日：1993-09-15
申请人： Charles W. Neff
发明人： Charles W. Neff
IPC分类号： A61J1/00 , A61J1/20 , A61M5/178 , B65B3/00
CPC分类号： B65B3/006 , A61M5/1782 , A61J1/10 , A61J1/1475 , A61J1/201 , A61J1/2096 , A61M2205/581 , A61M2205/583 , A61M2205/585
摘要： A new and improved visual magnification apparatus for a syringe includes a base portion, a lens support portion attached to the base portion, and a magnifying lens attached to the lens support portion, wherein a syringe can be placed on the base portion and magnified by the magnifying lens. The base portion may include an internally concave cross-sectional contour that has a bottommost valley portion, such that a generally cylindrically-shaped syringe tends to rest in the valley portion under the influence of gravity. The base portion includes an ampule-supporting portion. The base portion also includes a slot portion capable of supporting a top portion of a syringe placed on the base portion. The base portion, the lens support portion, and the slot portion are in the form of a unified, integrated structure. The lens support portion may include an extension portion capable of retaining an ampule on the ampule-supporting portion of the base portion. An ampule alignment assembly may be connected to the base portion. An illumination assembly may be supported by the base portion. The location of the illumination assembly on the base portion is in opposition to the magnifying lens, such that the illumination assembly provides backlighting for the syringe when the syringe is positioned between the magnifying lens and the illumination assembly. An audible signalling assembly may be connected to either the base portion or to the lens support portion for providing an audible signal relating to syringe volume.
摘要翻译：用于注射器的新的改进的视觉放大装置包括基部，附接到基部的透镜支撑部和附接到透镜支撑部的放大透镜，其中注射器可以放置在基部上并被放大放大镜基部可以包括内凹的横截面轮廓，其具有最底部的谷部分，使得大致圆柱形的注射器倾向于在重力的作用下在谷部中停留。基部包括安瓿支撑部。基部还包括能够支撑放置在基部上的注射器顶部的槽部。基部，透镜支撑部分和狭槽部分是统一的整体结构的形式。透镜支撑部分可以包括能够将安瓿保持在基部的安瓿支撑部分上的延伸部分。安瓿对准组件可以连接到基部。照明组件可以由基部支撑。照明组件在基部上的位置与放大镜相对，使得当注射器位于放大镜和照明组件之间时，照明组件为注射器提供背光。声音信号组件可以连接到基座部分或透镜支撑部分，以提供与注射器体积相关的可听见的信号。

58. 发明授权

US5056744A Syringe bottle support apparatus 失效
标题翻译：注射器瓶支持装置
公开(公告)号：US5056744A
公开(公告)日：1991-10-15
申请号：US619388
申请日：1990-11-29
申请人： John G. Ludwig
发明人： John G. Ludwig
IPC分类号： A61J1/00 , A61J1/20
CPC分类号： A61J1/2096 , A61J1/16 , A61J1/201 , A61J1/2055 , A61J1/2065 , A61M2205/583 , A61M2205/585 , A61M2209/084
摘要： An apparatus arranged to fixedly mount a syringe bottle in a downwardly angulated orientation, including a support member formed with a concave semi-cylindrical sleeve, with the sleeve mounting an elastomeric band selectively securable to a side of the sleeve for assembly of the bottle to the sleeve to permit access of the bottle in filling of a syringe therefrom. A modification of the invention includes illumination structure to enhance visibility of the organization in use.
摘要翻译：一种被布置成将注射器瓶固定地安装在向下成角度的方向上的装置，包括形成有凹形半圆柱形套筒的支撑构件，套筒安装弹性体带，其可选择性地固定到套筒的侧面，用于将瓶组装到套筒以允许瓶子从其中填充注射器进入。本发明的修改包括照明结构，以增强组织在使用中的可视性。

59. 发明公开

US20240066206A1 TEMPERATURE INDICATOR FOR DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20240066206A1
公开(公告)日：2024-02-29
申请号：US17767475
申请日：2020-09-29
申请人： AMGEN INC.
发明人： Heejin Lee , Daniel Eduardo Groszmann , Sheldon B. Moberg , Mohammad Bonakdar , Rasmus Ohlenschlaeger
IPC分类号： A61M5/142
CPC分类号： A61M5/142 , A61M2205/123 , A61M2205/3368 , A61M2205/3633 , A61M2205/584 , A61M2205/585 , A61M2207/00
摘要： A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle assembly, and a temperature indicator. The housing defines an inner volume and includes at least one opening. The container contains a medicament which is urged out of the container by the activation mechanism. The needle assembly has a needle and/or a cannula to deliver the medicament from the container. The temperature indicator is operably coupled with the outer surface of the container and is responsive to a change in temperature of the container.

60. 发明公开

US20240050659A1 HOUSING COMPONENT OF AN INJECTION DEVICE COMPRISING A MAGNIFIER 审中-公开
公开(公告)号：US20240050659A1
公开(公告)日：2024-02-15
申请号：US18267522
申请日：2022-01-03
申请人： Sanofi
发明人： Michael Helmer , Martin Vitt
IPC分类号： A61M5/24 , A61M5/20 , A61M5/31
CPC分类号： A61M5/24 , A61M5/20 , A61M5/31 , A61M2005/2006 , A61M2005/2403 , A61M2005/3125 , A61M2205/585
摘要： An elongated housing component of an injection device, the elongated housing component including a body comprising a first longitudinal end, an intermediate section, and a second longitudinal end opposite to the first longitudinal end. The intermediate section is located longitudinally between the first longitudinal end and the second longitudinal end. The body includes a sidewall extending from the first longitudinal end to the second longitudinal end. The sidewall confining a hollow interior space sized to accommodate a medicament container. The elongated housing component including a magnifier extending through the sidewall or integrated into the sidewall to increase a visual appearance of at least a portion of the medicament container when arranged inside the hollow interior space.

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