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1. 发明授权

US09999732B2 Drug injection device with particular optical window elements for unambiguous legibility of dose value 有权
公开(公告)号：US09999732B2
公开(公告)日：2018-06-19
申请号：US14773325
申请日：2014-03-10
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Naceur Rekaya , David Aubrey Plumptre , Paul Richard Draper
IPC分类号： A61M3/00 , A61M5/315 , A61M5/24 , A61M5/31
CPC分类号： A61M5/31525 , A61M5/24 , A61M2005/3126 , A61M2205/58 , A61M2205/585
摘要： An arrangement comprising an optical element and an indication member for a drug delivery device is provided. The indication member comprises a plurality of indicia. The optical element comprises an imaging section and a light-transmissive non-imaging section, wherein the indication member is movable with respect to the optical element such that the indicia can be successively moved into a display position relative to the optical element. The imaging section is configured such that, when a first indicium is arranged in the display position, the first indicium is imaged by the imaging section into an imaging solid angle. The non-imaging section is configured such that light defining a second indicium is deflected by the non-imaging section such that the second indicium cannot be identified by a user in the imaging solid angle on a viewing side of the optical element.

2. 发明申请

US20170319784A1 Drive Mechanism for use in a Drug Delivery Device 审中-公开
公开(公告)号：US20170319784A1
公开(公告)日：2017-11-09
申请号：US15532432
申请日：2015-12-08
申请人： Sanofi
发明人： William Geoffrey Arthur Marsh , Matthew Meredith Jones , Joseph Butler , Anthony Paul Morris
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315
CPC分类号： A61M5/2033 , A61M5/2422 , A61M5/2466 , A61M5/31511 , A61M5/31536 , A61M5/31541 , A61M5/31553 , A61M5/3157 , A61M5/31585 , A61M5/31593 , A61M2005/2026 , A61M2005/31518 , A61M2205/581 , A61M2205/582 , A61M2205/584 , A61M2205/585
摘要： The disclosure is directed to a drive mechanism for use in a drug delivery device having a cartridge, the mechanism comprising a base element, a toothed piston rod movable from a first retracted position corresponding to a full cartridge to a second extended position corresponding to an empty cartridge, wherein the piston rod is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod, wherein the toothed piston rod comprises multiple rigid rod pieces which are connected by hinges, and a drive spring, which is fixed to the base element with one end and fixed to the drive gear with another end and which exerts a force or torque to the drive gear for rotating the drive gear relative to the base element, which rotation results in a movement of the toothed piston rod. The drive spring is charged during manufacture or assembly, wherein the energy stored in the drive spring is sufficient to move the piston rod (from the first to the second position. The disclosure is also directed to a drug delivery device.

3. 发明申请

US20170136186A1 Drug Delivery Device 审中-公开
公开(公告)号：US20170136186A1
公开(公告)日：2017-05-18
申请号：US15321900
申请日：2015-07-01
申请人： Sanofi
发明人： William MARSH , Anthony Paul MORRIS , Joseph BUTLER , Matthew JONES , Samuel STEEL , Richard James Vincent AVERY
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/2033 , A61M5/3146 , A61M5/31511 , A61M5/31515 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/31583 , A61M5/31585 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/585
摘要： The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10) and a clutch mechanism arranged between the number sleeve (60) and the drive sleeve (40). The clutch mechanism comprises a first interface (42, 62) for rotationally constraining the drive sleeve (40) and the number sleeve (60) depending on the axial position of the drive sleeve (40) and a second interface (43, 121) for rotationally constraining the drive sleeve (40) and the number sleeve (60) via a clutch element (120) depending on the axial position of the drive sleeve (40) and/or the bias of a clutch spring (130).

4. 发明申请

US20160058951A1 Drug Injection Device with Particular Optical Window Elements for Unambiguous Legibility of Dose Value 有权
标题翻译：具有特定光学窗口元件的药物注射装置，用于剂量值的明确可读性
公开(公告)号：US20160058951A1
公开(公告)日：2016-03-03
申请号：US14773325
申请日：2014-03-10
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Naceur Rekaya , David Aubrey Plumptre , Paul Richard Draper
IPC分类号： A61M5/315
CPC分类号： A61M5/31525 , A61M5/24 , A61M2005/3126 , A61M2205/58 , A61M2205/585
摘要： An arrangement comprising an optical element and an indication member for a drug delivery device is provided. The indication member comprises a plurality of indicia. The optical element comprises an imaging section and a light-transmissive non-imaging section, wherein the indication member is movable with respect to the optical element such that the indicia can be successively moved into a display position relative to the optical element. The imaging section is configured such that, when a first indicium is arranged in the display position, the first indicium is imaged by the imaging section into an imaging solid angle. The non-imaging section is configured such that light defining a second indicium is deflected by the non-imaging section such that the second indicium cannot be identified by a user in the imaging solid angle on a viewing side of the optical element.
摘要翻译：提供了一种包括光学元件和用于药物输送装置的指示构件的装置。指示构件包括多个标记。光学元件包括成像部分和透光非成像部分，其中指示部件可相对于光学元件移动，使得标记可以相对于光学元件连续移动到显示位置。成像部被配置为使得当第一标记被布置在显示位置时，第一标记被成像部分成像为成像立体角。非成像部分被配置为使得限定第二标记的光被非成像部分偏转，使得第二标记不能由光学元件的观察侧上的成像立体角中的用户识别。

5. 发明申请

US20160038700A1 AIRWAY ADAPTERS AND SUCTION CATHETER SYSTEMS 审中-公开
标题翻译： AIRWAY ADAPTERS和SUCTION导管系统
公开(公告)号：US20160038700A1
公开(公告)日：2016-02-11
申请号：US14821438
申请日：2015-08-07
申请人： CareFusion 2200, Inc.
发明人： Dennis WHITE , Haojun FU , Sibgat ULLA , Ming LU , Christopher VARGA , Simon JUNG , Charles Edward BEUCHAT
IPC分类号： A61M16/04 , A61M16/20 , A61M16/08
CPC分类号： A61M16/0463 , A61M16/0825 , A61M16/0833 , A61M16/208 , A61M2205/276 , A61M2205/585
摘要： Airway adapters and suction catheter systems, and methods of using the same, are described herein. An exemplary airway adapter assembly may comprise a connector body portion having a first end and a second end. The connector body portion may define an elongate cavity having an axial center between the first and the second end. The exemplary airway adapter assembly may also comprise a valve coupled to the second end of the connector body. The exemplary airway adapter assembly may also comprise a ventilation base member comprising a tubular portion coupled to the second end of the connector body portion and ventilator port. The ventilator port may comprises a conduit having a first conduit end and a second conduit end, and the first conduit end may be coupled to the tubular portion through an articulable connection. An exemplary closed suction catheter system may comprise a suction control valve assembly and a closed suction catheter sheath.
摘要翻译：气道适配器和抽吸导管系统及其使用方法在本文中描述。示例性气道适配器组件可以包括具有第一端和第二端的连接器主体部分。连接器主体部分可以限定在第一和第二端之间具有轴向中心的细长腔。示例性气道适配器组件还可以包括联接到连接器主体的第二端的阀。示例性气道适配器组件还可以包括通风基座构件，其包括联接到连接器主体部分的第二端和通气机端口的管状部分。呼吸机端口可以包括具有第一导管端和第二导管端的导管，并且第一导管端可以通过可铰接的连接件联接到管状部分。示例性的闭合抽吸导管系统可以包括抽吸控制阀组件和封闭的抽吸导管护套。

6. 发明授权

US09220845B2 Medication injector apparatus with drive assembly that facilitates reset 有权
标题翻译：具有驱动组件的药物注射器装置便于复位
公开(公告)号：US09220845B2
公开(公告)日：2015-12-29
申请号：US14163498
申请日：2014-01-24
申请人： Eli Lilly and Company
发明人： William Godwin Atterbury , Mark Gerard Diller , Shannon Marie-Lynn Hoste , Bobby Lee Walters , Steven Michael Madland
IPC分类号： A61M5/315 , G01D5/249 , G01D5/25 , A61B17/00 , A61M5/24 , A61M5/31
CPC分类号： A61M5/31535 , A61B2017/00482 , A61M5/24 , A61M5/3129 , A61M5/31543 , A61M5/31551 , A61M5/31556 , A61M5/31558 , A61M5/31566 , A61M5/31568 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/2488 , A61M2005/3125 , A61M2205/50 , A61M2205/581 , A61M2205/583 , A61M2205/585 , A61M2205/60 , A61M2205/6027 , G01D5/2497 , G01D5/25
摘要： A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.
摘要翻译：药剂注射器装置，例如注射笔。注射笔包括可重置的柱塞驱动组件，其包括轴向浮动的螺母，柱塞接合螺钉和可与螺母一起移动的驱动离合器，并且当旋转时，螺杆通过螺母旋紧。当墨盒组件安装到笔底座时，浮动螺母和驱动离合器向近侧移动，使得驱动离合器与笔的可旋转驱动构件扭转传递接合，使得该驱动构件的旋转导致驱动螺钉通过螺母在远端方向前进。当墨盒组件没有安装到笔底座上时，浮动螺母和驱动离合器被向远侧偏压以使驱动离合器与可旋转驱动构件的扭矩传递接合脱离，从而允许驱动螺钉通过螺母向近侧复位到在笔底座内更缩进的位置。注射笔还可以包括具有同轴地布置在驱动套筒上并在驱动套筒上轴向振动的注射打印机组件，其在药物分配期间旋转以提供指示注射使用笔的可听到的咔嗒声。注射笔还可以包括使用旋转矩阵和用于电感测笔的剂量设定机构的布置的传感器的剂量量标识符，该标识符可以是利用盒识别器识别的治疗剂量指示系统的一部分药物浓度以允许治疗剂量的自动测定。注射笔还可以包括用于选择性地旋转笔的驱动套筒的组件，该组件具有在剂量设定期间旋转并且在剂量注射期间不转动的转盘。

7. 发明申请

US20150065960A1 PEN -TYPE INJECTOR WITH WINDOW ELEMENT 审中-公开
标题翻译： PEN-TYPE INJECTOR WITH WINDOW ELEMENT
公开(公告)号：US20150065960A1
公开(公告)日：2015-03-05
申请号：US14389570
申请日：2013-04-02
申请人： SANOFI-AVENTIS DEUTSCHLAND GmbH
发明人： Thomas Frederick Osman
IPC分类号： A61M5/24
CPC分类号： A61M5/24 , A61M5/142 , A61M5/3129 , A61M2005/3125 , A61M2005/3126 , A61M2205/19 , A61M2205/583 , A61M2205/585 , A61M2207/00
摘要： The present invention is directed to a housing for a drug delivery device. The housing comprises an outer shell with an aperture, an insert received within the aperture and a clamp attached to the outer shell. The insert has at least one recess which is engaged by a lug of the clamp to retain the insert within the aperture of the outer shell. The invention is further directed to a pen-type injector having such a housing.
摘要翻译：本发明涉及一种用于药物输送装置的壳体。壳体包括具有孔的外壳，容纳在孔内的插入件和附接到外壳的夹具。插入件具有至少一个凹部，该凹槽由夹具的凸耳接合，以将插入件保持在外壳的孔内。本发明还涉及具有这种壳体的笔式注射器。

8. 发明授权

US08801680B2 Angled retracting sheath for safety needle 有权
标题翻译：用于安全针的角度缩回护套
公开(公告)号：US08801680B2
公开(公告)日：2014-08-12
申请号：US13793831
申请日：2013-03-11
申请人： Andrew Wong , Matthew Zachek
发明人： Andrew Wong , Matthew Zachek
IPC分类号： A61M5/00
CPC分类号： A61M5/3213 , A61M5/3243 , A61M5/3287 , A61M5/3293 , A61M5/34 , A61M5/46 , A61M2205/585 , F04C2270/0421
摘要： A safety needle device having a housing, a retractable sheath, and a needle cannula. The retractable sheath includes a tubular portion that is slideably mounted about a portion of the housing to completely or partially encase the length of the cannula. The retractable sheath includes a sheath bevel at the distal end having a blunted or angled tip. The angled tip being configured to suitable injection angles and may be fixed or rotatable. The sheath bevel may include a skin-engaging contact surface at the distal end. The needle may be connected to a needle hub at the proximal end of the housing and includes a needle bevel at the distal end. The sheath bevel and needle bevel may be offset from each other. A safety needle device having a retractable sheath having a graduated injection depth gauge to indicate needle penetration is also disclosed.
摘要翻译：一种具有外壳，可伸缩护套和针套管的安全针装置。可伸缩护套包括可绕壳体的一部分可滑动地安装的管状部分，以完全或部分地包围套管的长度。可伸缩护套包括在远端具有钝角或倾斜尖端的护套斜面。倾斜的尖端构造成适合的注射角度并且可以是固定的或可旋转的。护套斜面可以包括在远端处的皮肤接合的接触表面。针可以在壳体的近端处连接到针座，并且在远端处包括针斜面。护套斜面和针斜面可能彼此偏移。还公开了具有可伸缩护套的安全针装置，其具有用于指示穿刺的刻度注射深度计。

9. 发明授权

US08647309B2 Medication delivery device 有权
标题翻译：药物输送装置
公开(公告)号：US08647309B2
公开(公告)日：2014-02-11
申请号：US12194709
申请日：2008-08-20
申请人： Michael Harms , James Robert Howarth , Robin Craig Cocker , George Richard Gregory , Anthony Raymond Charpentier , Michael Strehl , Udo Leuschner , Norbert Besenhardt
发明人： Michael Harms , James Robert Howarth , Robin Craig Cocker , George Richard Gregory , Anthony Raymond Charpentier , Michael Strehl , Udo Leuschner , Norbert Besenhardt
IPC分类号： A61M5/00
CPC分类号： A61M5/31541 , A61M5/24 , A61M5/3129 , A61M5/31543 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2005/2407 , A61M2005/2488 , A61M2005/3142 , A61M2205/581 , A61M2205/582 , A61M2205/585 , Y10T29/49826
摘要： The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.
摘要翻译：本发明涉及药物输送装置，适用于这种药物输送装置中的给药机构，特别是在笔式注射器中，优选具有剂量设定构件和能够进行剂量设定和药物施用的驱动装置来自多剂量药物盒的产品，使用这种装置的方法，以及制造和组装这种装置的方法。

10. 发明申请

US20130261565A1 Angled Retracting Sheath for Safety Needle 有权
标题翻译：安全针角度缩回护套
公开(公告)号：US20130261565A1
公开(公告)日：2013-10-03
申请号：US13793831
申请日：2013-03-11
申请人： Andrew Wong , Matthew Zachek
发明人： Andrew Wong , Matthew Zachek
IPC分类号： A61M5/32
CPC分类号： A61M5/3213 , A61M5/3243 , A61M5/3287 , A61M5/3293 , A61M5/34 , A61M5/46 , A61M2205/585 , F04C2270/0421
摘要： A safety needle device having a housing, a retractable sheath, and a needle cannula. The retractable sheath includes a tubular portion that is slideably mounted about a portion of the housing to completely or partially encase the length of the cannula. The retractable sheath includes a sheath bevel at the distal end having a blunted or angled tip. The angled tip being configured to suitable injection angles and may be fixed or rotatable. The sheath bevel may include a skin-engaging contact surface at the distal end. The needle may be connected to a needle hub at the proximal end of the housing and includes a needle bevel at the distal end. The sheath bevel and needle bevel may be offset from each other. A safety needle device having a retractable sheath having a graduated injection depth gauge to indicate needle penetration is also disclosed.
摘要翻译：一种具有外壳，可伸缩护套和针套管的安全针装置。可伸缩护套包括可绕壳体的一部分可滑动地安装的管状部分，以完全或部分地包围套管的长度。可伸缩护套包括在远端具有钝角或倾斜尖端的护套斜面。倾斜的尖端构造成适合的注射角度并且可以是固定的或可旋转的。护套斜面可以包括在远端处的皮肤接合的接触表面。针可以在壳体的近端处连接到针座，并且在远端处包括针斜面。护套斜面和针斜面可能彼此偏移。还公开了具有可伸缩护套的安全针装置，其具有用于指示穿刺的刻度注射深度计。

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