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51. 发明授权

US4643924A Protective article comprising an elastic gel 失效
标题翻译：包含弹性凝胶的保护制品
公开(公告)号：US4643924A
公开(公告)日：1987-02-17
申请号：US730699
申请日：1985-05-02
申请人： William D. Uken , Robert S. Dubrow
发明人： William D. Uken , Robert S. Dubrow
IPC分类号： B32B1/00 , B05B15/04 , B05C17/06 , B05D1/32 , B29C51/14 , B29C61/06 , B29C63/22 , B32B7/02 , B32B27/00 , B65D59/06 , B65D75/36 , C23F11/00 , C23F15/00 , F16L58/18 , G02B6/44 , H01B1/20 , H01R4/70 , H01R4/72 , H01R13/52 , H01R43/00 , H02G15/00 , H02G15/18 , B32B1/02 , B32B1/04 , B32B1/08
CPC分类号： H02G15/18 , B65D75/36 , F16L58/18 , G02B6/4447 , H01R13/5216 , H01R4/70 , H01R43/005 , H02G15/003 , H01R4/72 , Y10T428/1352 , Y10T428/1386 , Y10T428/249994 , Y10T428/31554 , Y10T428/31663
摘要： An article for protecting a substrate includes a preshaped member having a shape similar to that of the substrate being protected, the article having a thin layer of gel disposed in intimate contact with an inner surface of the member such that the gel is disposed in intimate contact with the substrate when the member is disposed therearound. Preferably, the gel comprises an open looped three-dimensional network, the gel being relatively soft, elastic, and having an ultimate elongation in excess of 100%.

52. 发明授权

US08956637B2 Medical device applications of nanostructured surfaces 有权
标题翻译：纳米结构表面的医疗器械应用
公开(公告)号：US08956637B2
公开(公告)日：2015-02-17
申请号：US13096919
申请日：2011-04-28
申请人： Robert S. Dubrow , Lawrence A. Bock , R. Hugh Daniels , Veeral D. Hardev , Chunming Niu , Vijendra Sahi
发明人： Robert S. Dubrow , Lawrence A. Bock , R. Hugh Daniels , Veeral D. Hardev , Chunming Niu , Vijendra Sahi
IPC分类号： A61F13/00 , A61F13/06 , A61L26/00 , B32B19/04 , A61L31/10 , A61F13/02 , A61L27/34 , A61F5/40 , A61F15/00 , A61N1/05 , B82Y30/00
CPC分类号： A61L31/10 , A61F13/02 , A61L27/34 , A61L2400/12 , A61L2420/04 , A61N1/05 , B82Y30/00 , Y10S977/762 , Y10S977/764 , Y10S977/773 , Y10S977/811 , Y10S977/813 , Y10S977/90 , Y10S977/904 , Y10S977/906 , Y10T428/12111 , Y10T428/249924 , Y10T428/29
摘要： This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.
摘要翻译：本发明提供了新颖的纳米纤维增强表面积基材和包括用于各种医疗装置的这种基底的结构，以及用于这种基底和医疗装置的方法和用途。在一个具体实施例中，公开了用于增强医疗装置植入物表面上的细胞功能的方法，其通常包括提供包括在其上的多个纳米纤维（例如，纳米线）的医疗装置植入物，并将医疗装置植入物暴露于诸如成骨细胞。

53. 发明授权

US08749130B2 Nanocrystal doped matrixes 有权
标题翻译：纳米晶体掺杂基质
公开(公告)号：US08749130B2
公开(公告)日：2014-06-10
申请号：US12039018
申请日：2008-02-28
申请人： J. Wallace Parce , Jian Chen , Robert S. Dubrow , William P. Freeman , Erik C. Scher , Jeffery A. Whiteford
发明人： J. Wallace Parce , Jian Chen , Robert S. Dubrow , William P. Freeman , Erik C. Scher , Jeffery A. Whiteford
IPC分类号： H01J1/62 , H01J63/04 , C09K11/54 , C09K11/56 , C09K11/02
CPC分类号： C09K11/02 , B82Y20/00 , B82Y30/00 , C08K3/30 , C09D5/00 , C09D7/61 , C09D7/67 , C09D11/037 , C09K11/565 , C09K11/883 , G02B1/11 , G02B3/00 , G02B3/0006 , G02B5/08 , H01L33/502 , H01L33/504 , H01L33/56 , H05B33/145 , Y10S977/715 , Y10S977/753 , Y10S977/834 , Y10T428/23 , Y10T428/239
摘要： The present invention provides matrixes doped with semiconductor nanocrystals. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes of the present invention can also be utilized in refractive index matching applications. In other embodiments, semiconductor nanocrystals are embedded within matrixes to form a nanocrystal density gradient, thereby creating an effective refractive index gradient. The matrixes of the present invention can also be used as filters and antireflective coatings on optical devices and as down-converting layers. The present invention also provides processes for producing matrixes comprising semiconductor nanocrystals.
摘要翻译：本发明提供掺杂有半导体纳米晶体的矩阵。在某些实施方案中，半导体纳米晶体具有使其吸收或发射特定波长的光的尺寸和组成。纳米晶体可以包括允许与各种基质材料（包括聚合物）混合的配体，使得最小部分的光被基质散射。本发明的基质也可用于折射率匹配应用。在其它实施例中，将半导体纳米晶体嵌入在基质内以形成纳米晶体密度梯度，从而产生有效的折射率梯度。本发明的基质也可以用作光学器件上的滤光片和抗反射涂层以及下变换层。本发明还提供了用于生产包含半导体纳米晶体的基质的方法。

54. 发明授权

US08592141B2 Western blot by incorporating an affinity purification zone 有权
标题翻译：通过掺入亲和纯化区的蛋白质印迹
公开(公告)号：US08592141B2
公开(公告)日：2013-11-26
申请号：US13216441
申请日：2011-08-24
申请人： Matthew B Murphy , Robert S. Dubrow
发明人： Matthew B Murphy , Robert S. Dubrow
IPC分类号： C12Q1/00
CPC分类号： G01N33/54366
摘要： A mixture of components is flowed through a binding channel region comprising a component-binding moiety, thereby binding at least a portion of a component of interest. The mixture is then flowed through a separation channel region that includes a buffer comprising a detergent, resulting in separated components. Diluent is mixed with the separated components, diluting the detergent, and the separated components are detected. The component of interest is released from the component-binding moiety and flowed through the separation channel region. Diluent is mixed with the released component of interest, diluting the detergent, and the released component of interest is detected.
摘要翻译：组分的混合物流过包含组分结合部分的结合通道区，从而结合目的组分的至少一部分。然后将混合物流过包括包含洗涤剂的缓冲液的分离通道区域，得到分离的组分。将稀释剂与分离的组分混合，稀释洗涤剂，并检测分离的组分。感兴趣的组分从组分结合部分释放并流过分离通道区。将稀释液与所释放的感兴趣组分混合，稀释洗涤剂，并检测释放的感兴趣组分。

55. 发明授权

US08304595B2 Resorbable nanoenhanced hemostatic structures and bandage materials 有权
标题翻译：可再吸收的纳米增强止血结构和绷带材料
公开(公告)号：US08304595B2
公开(公告)日：2012-11-06
申请号：US12329431
申请日：2008-12-05
申请人： R. Hugh Daniels , Robert S. Dubrow , Robert Enzerink , Esther Li , Vijendra Sahi , Jay L. Goldman , J. Wallace Parce
发明人： R. Hugh Daniels , Robert S. Dubrow , Robert Enzerink , Esther Li , Vijendra Sahi , Jay L. Goldman , J. Wallace Parce
IPC分类号： A61F13/00 , A61F13/02
CPC分类号： A61F13/00034 , A61B17/0057 , A61B17/064 , A61B2017/00601 , A61B2017/00884 , A61B2017/00893 , A61F13/00008 , A61F13/00991 , A61F13/36 , A61F2013/00472 , A61F2013/0054 , A61F2013/00744 , A61F2013/00927 , A61F2013/00931 , A61L15/18 , A61L15/42 , A61L17/145 , A61L26/0004 , A61L26/0095 , A61L31/082 , A61L31/128 , A61L2400/04 , A61L2400/12 , D06M23/08
摘要： Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.
摘要翻译：提供了纳米材料增强型止血医疗装置的方法，系统和装置。提供止血材料和结构，其在创伤，外科手术，溃疡或其他原因引起的伤口/开口处引起血液凝血。止血材料和结构可以结合纳米结构和/或其它止血元件，例如聚合物和/或玻璃珠。止血材料和结构可以是可再吸收的。示例性实施例包括止血绷带，止血塞和止血配方。

56. 发明申请

US20120113672A1 Quantum dot films, lighting devices, and lighting methods 有权
标题翻译：量子点薄膜，照明装置和照明方法
公开(公告)号：US20120113672A1
公开(公告)日：2012-05-10
申请号：US13287616
申请日：2011-11-02
申请人： Robert S. Dubrow , William P. Freeman , Ernest Lee , Paul Furuta
发明人： Robert S. Dubrow , William P. Freeman , Ernest Lee , Paul Furuta
IPC分类号： F21V8/00 , B32B5/16 , F21V9/16 , B32B9/04 , B82Y20/00
CPC分类号： G02B6/0055 , B32B5/16 , B32B9/04 , B32B2313/00 , B32B2457/202 , B32B2551/00 , B82Y20/00 , F21V9/30 , F21Y2115/10 , G02B6/005 , G02B6/0053 , G02B6/0061 , G02B6/0068 , G02B6/0073 , G02F1/133611 , G02F2001/133614 , Y10S977/774 , Y10T428/31504
摘要： Light-emitting quantum dot films, quantum dot lighting devices, and quantum dot-based backlight units are provided. Related compositions, components, and methods are also described. Improved quantum dot encapsulation and matrix materials are provided. Quantum dot films with protective barriers are described. High-efficiency, high brightness, and high-color purity quantum dot-based lighting devices are also included, as well as methods for improving efficiency and optical characteristics in quantum dot-based lighting devices.
摘要翻译：提供了发光量子点膜，量子点照明装置和量子点式背光单元。还描述了相关的组合物，组分和方法。提供了改进的量子点封装和基质材料。描述了具有保护屏障的量子点膜。还包括高效率，高亮度和高色纯度的量子点照明装置，以及用于提高量子点照明装置的效率和光学特性的方法。

57. 发明授权

US07829351B2 Methods, devices and compositions for depositing and orienting nanostructures 有权
公开(公告)号：US07829351B2
公开(公告)日：2010-11-09
申请号：US11507631
申请日：2006-08-21
申请人： Robert S. Dubrow , Linda T. Romano , David P. Stumbo
发明人： Robert S. Dubrow , Linda T. Romano , David P. Stumbo
IPC分类号： H01L21/00 , H01L21/31
CPC分类号： H01L21/02422 , B82Y10/00 , B82Y20/00 , B82Y30/00 , C30B7/00 , H01L21/02381 , H01L21/02521 , H01L21/02603 , H01L21/02656 , Y10S977/762 , Y10S977/827
摘要： Methods and systems for depositing nanomaterials onto a receiving substrate and optionally for depositing those materials in a desired orientation, that comprise providing nanomaterials on a transfer substrate and contacting the nanomaterials with an adherent material disposed upon a surface or portions of a surface of a receiving substrate. Orientation is optionally provided by moving the transfer and receiving substrates relative to each other during the transfer process.

58. 发明申请

US20090181228A1 METHODS OF FABRICATING POLYMERIC STRUCTURES INCORPORATING MICROSCALE FLUIDIC ELEMENTS 审中-公开
标题翻译：制备微波流体元素的聚合物结构方法
公开(公告)号：US20090181228A1
公开(公告)日：2009-07-16
申请号：US12407664
申请日：2009-03-19
申请人： Khushroo Gandhi , Robert S. Dubrow , Luc J. Bousse
发明人： Khushroo Gandhi , Robert S. Dubrow , Luc J. Bousse
IPC分类号： B32B7/02 , B32B5/00
CPC分类号： G01N27/44791 , B01L3/502707 , B01L2200/12 , B07C5/342 , B29C65/02 , B29C65/08 , B29C65/8253 , B29C66/30223 , B29C66/54 , B29C66/71 , B29C66/712 , B29C66/723 , B29C66/73115 , B29C66/73343 , B29C66/73365 , B29C66/8322 , B29L2031/756 , B32B37/0023 , B32B38/06 , B32B2037/0092 , B32B2310/028 , B32B2310/0843 , Y10T156/10 , Y10T428/2495 , Y10T428/266 , B29K2081/06 , B29K2069/00 , B29K2067/00 , B29K2055/02 , B29K2033/12 , B29K2027/18 , B29K2027/14 , B29K2027/06 , B29K2023/18 , B29K2023/12 , B29K2023/06
摘要： The present invention provides a microfluidic device that includes first and second polymeric substrates. The first substrate has a higher transition temperature than the second substrate. A first substantially planar surface of the first substrate has a plurality of microscale channels disposed therein. A first substantially planar surface of the second substrate is thermally bonded to the first surface of the first substrate, neither of the first surfaces of the first and second substrates having an adhesive disposed thereon.
摘要翻译：本发明提供一种包括第一和第二聚合物基底的微流体装置。第一衬底具有比第二衬底更高的转变温度。第一基板的第一基本平坦的表面具有设置在其中的多个微通道。第二基板的第一基本上平坦的表面热粘合到第一基板的第一表面上，第一和第二基板的第一表面中没有一个粘合剂设置在其上。

59. 发明申请

US20090124034A1 Nanostructured Thin Films and Their Uses 失效
标题翻译：纳米结构薄膜及其用途
公开(公告)号：US20090124034A1
公开(公告)日：2009-05-14
申请号：US12121008
申请日：2008-05-15
申请人： Chunming Niu , R. Hugh Daniels , Robert S. Dubrow , Jay L. Goldman
发明人： Chunming Niu , R. Hugh Daniels , Robert S. Dubrow , Jay L. Goldman
IPC分类号： H01L21/30
CPC分类号： A61L27/303 , A61L31/122 , H01J49/0418 , Y10S977/701 , Y10T428/12736 , Y10T428/12743
摘要： The present invention generally discloses the use of a nanostructured non-silicon thin film (such as an alumina or aluminum thin film) on a supporting substrate which is subsequently coated with an active layer of a material such as silicon or tungsten. The base, underlying non-silicon material generates enhanced surface area while the active layer assists in incorporating and transferring energy to one or more analytes adsorbed on the active layer when irradiated with a laser during laser desorption of the analyte(s). The present invention provides substrate surfaces that can be produced by relatively straightforward and inexpensive manufacturing processes and which can be used for a variety of applications such as mass spectrometry, hydrophobic or hydrophilic coatings, medical device applications, electronics, catalysis, protection, data storage, optics, and sensors.
摘要翻译：本发明一般公开了在支撑衬底上使用纳米结构非硅薄膜（例如氧化铝或铝薄膜），随后用诸如硅或钨的材料的活性层涂覆。底层的非硅材料产生增强的表面积，而活性层有助于在分析物的激光解吸附中用激光照射时，将能量并入和转移到吸附在活性层上的一种或多种分析物。本发明提供了可以通过相对直接和廉价的制造方法制造的衬底表面，其可用于各种应用，例如质谱，疏水或亲水涂层，医疗器械应用，电子学，催化，保护，数据存储，光学和传感器。

60. 发明授权

US07419784B2 Methods, systems and apparatus for separation and isolation of one or more sample components of a sample biological material 有权
标题翻译：用于分离和分离样品生物材料的一种或多种样品组分的方法，系统和装置
公开(公告)号：US07419784B2
公开(公告)日：2008-09-02
申请号：US10401110
申请日：2003-03-27
申请人： Robert S. Dubrow , Luc J. Bousse , Huan L. Phan
发明人： Robert S. Dubrow , Luc J. Bousse , Huan L. Phan
IPC分类号： G01N33/53
CPC分类号： B01L3/50273 , B01L3/502715 , B01L3/502753 , B01L3/502784 , B01L2200/0605 , B01L2200/0631 , B01L2200/10 , B01L2300/0816 , B01L2400/0421 , B01L2400/0487 , G01N27/44791 , Y10T436/25
摘要： Devices, systems and methods for use in separating sample materials into different sample components and then isolating one or more of the sample components for further processing or analysis are disclosed. Devices employ configurations that optionally allow a sample material to be electrophoretically separated into sample components in a separation matrix within a separation conduit. The sample components may then be detected in a detection zone in the separation conduit, and then selected components shunted to a component collection conduit within the device downstream of the detection zone for further processing or analysis based on information received at the detection zone. Methods of using these devices, and systems that incorporate these devices are also envisioned.
摘要翻译：公开了用于将样品材料分离成不同样品组分，然后分离一个或多个样品组分用于进一步处理或分析的装置，系统和方法。设备采用可选地允许样品材料在分离管道内的分离基质中电泳分离成样品组分的构型。然后可以在分离管道中的检测区域中检测样品组分，然后根据在检测区域接收的信息，将选定的组分分流到检测区域下游装置内的组件收集管道进一步处理或分析。也可以设想使用这些装置的方法以及包含这些装置的系统。

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