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41. 发明授权

US4382076A Hepatitis A antibody assay 失效
标题翻译：甲型肝炎抗体测定
公开(公告)号：US4382076A
公开(公告)日：1983-05-03
申请号：US383668
申请日：1982-06-01
申请人： William M. Hurni , William J. Miller , William J. McAleer
发明人： William M. Hurni , William J. Miller , William J. McAleer
IPC分类号： G01N33/576 , G01N33/48 , G01N33/54 , C12Q1/70
CPC分类号： G01N33/5768 , Y10S435/961 , Y10S435/962 , Y10S436/804 , Y10S436/82
摘要： A diagnostic reagent for hepatitis A antibody is prepared by adhering hepatitis A antibody to a surface by non-specific adsorption followed by specific coupling of hepatitis A antigen to the antibody. This reagent is useful in an in vitro assay for hepatitis A antibody.
摘要翻译：通过非特异性吸附将甲型肝炎抗体粘附到表面，然后将甲型肝炎抗原与抗体特异性偶联来制备用于甲型肝炎抗体的诊断试剂。该试剂可用于甲型肝炎抗体的体外测定。

42. 发明授权

US4329424A Macroscopic method for determining cytopathic effects in viral assay 失效
标题翻译：用于确定病毒测定中细胞病变效应的宏观方法
公开(公告)号：US4329424A
公开(公告)日：1982-05-11
申请号：US881299
申请日：1978-02-27
申请人： Roy A. Machlowitz , William J. McAleer , William J. Miller
发明人： Roy A. Machlowitz , William J. McAleer , William J. Miller
IPC分类号： C12Q1/70 , G01N1/28 , G01N1/30 , G01N33/54
CPC分类号： C12Q1/70
摘要： Semi-automated assays for viral infectivity and an assay for serum neutralizing antibody content are based on staining the cells and macroscopic reading of the cytopathic effect.
摘要翻译：用于病毒感染性的半自动化测定和血清中和抗体含量的测定是基于细胞的染色和细胞病变效应的宏观读数。

43. 发明授权

US4322576A Message format for secure communication over data links 失效
标题翻译：用于通过数据链路进行安全通信的消息格式
公开(公告)号：US4322576A
公开(公告)日：1982-03-30
申请号：US108039
申请日：1979-12-28
申请人： William J. Miller
发明人： William J. Miller
IPC分类号： H04K1/00 , H04L1/00 , H04L9/00 , H04L9/06 , H04L9/08 , H04L9/12 , H04L29/00 , H04L29/06
CPC分类号： D21H5/0002 , H04L1/0083 , H04L9/0625 , H04L9/0637 , H04L9/12 , H04L2209/60
摘要： Communication over data links using binary synchronous protocol that is to be made secure according to the Federal data encryption standard (DES) is enhanced by utilizing an encrypted message format wherein the initialization vector for the DES algorithm is at the trailing end of the message. Additional information or control words may also be strung at the trailing end of the encrypted message format without causing throughput loss while enhancing the security and flexibility of the encrypted message in both point-to-point and multipoint systems.
摘要翻译：使用根据联邦数据加密标准（DES）进行安全的二进制同步协议的数据链路的通信通过利用加密的消息格式得到增强，其中DES算法的初始化向量位于消息的后端。附加信息或控制字也可以在加密消息格式的尾端被串起，而不会导致吞吐量损失，同时增强点对点和多点系统中的加密消息的安全性和灵活性。

44. 发明授权

US4293538A Assay for hepatitis A antigen 失效
标题翻译：甲型肝炎抗原测定
公开(公告)号：US4293538A
公开(公告)日：1981-10-06
申请号：US31712
申请日：1979-04-20
申请人： William J. McAleer , William M. Hurni , William J. Miller
发明人： William J. McAleer , William M. Hurni , William J. Miller
IPC分类号： G01N33/576 , G01N33/48 , A61K43/00 , G01T1/00
CPC分类号： G01N33/5768 , Y10S436/81 , Y10S436/82
摘要： Liquid containing hepatitis A antibody is adsorbed on a surface. The surface is then coated with a proteinaceous material and incubated in the presence of the sample to form a complex of hepatitis A antigen and hepatitis A antibody. The complex is incubated again in the presence of excess radioactively labelled hepatitis A antibody, and the resulting radionuclide is measured.
摘要翻译：含有甲型肝炎抗体的液体被吸附在表面上。然后将表面用蛋白质材料包被，并在样品存在下孵育以形成甲型肝炎抗原和甲型肝炎抗体的复合物。在过量放射性标记的甲型肝炎抗体存在下再次培养该复合物，并测量所得的放射性核素。

45. 发明授权

US3959074A Vaccine production 失效
标题翻译：疫苗生产
公开(公告)号：US3959074A
公开(公告)日：1976-05-25
申请号：US530109
申请日：1974-12-06
申请人： William J. Miller , Raymond E. Spier , William J. McAleer
发明人： William J. Miller , Raymond E. Spier , William J. McAleer
IPC分类号： C12N5/00 , A61K39/12 , A61K39/20 , C12B1/00 , C12K7/00
CPC分类号： C12N5/0018
摘要： A process for the controlled manufacture of cells and vaccines in which reproducable real time quantitative assays are utilized to ascertain the physical and chemical state of the system, in order to more efficiently manage the system, so that cell sheet formation may be determined and the vaccine may be harvested at its maximum titre, thereby resulting in significantly increased yields and decreased production costs.
摘要翻译：用于控制制造细胞和疫苗的方法，其中利用可重复的实时定量测定法来确定系统的物理和化学状态，以便更有效地管理系统，从而可以确定细胞片形成并且疫苗可以以其最大滴定度收获，从而导致产量显着增加并降低生产成本。

46. 发明申请

US20140027247A1 CONVEYOR SPROCKET ASSEMBLY 有权
标题翻译：输送机组件
公开(公告)号：US20140027247A1
公开(公告)日：2014-01-30
申请号：US13561682
申请日：2012-07-30
申请人： Michael S. Cox , William J. Miller
发明人： Michael S. Cox , William J. Miller
IPC分类号： B65G23/06
CPC分类号： B65G23/06
摘要： A conveyor sprocket assembly generally includes a support shaft, at least one conveyor sprocket slidably engaging the support shaft, and an abutment stop positioned adjacent the conveyor sprocket. The abutment stop is configured to be removed to allow the conveyor sprocket to slide axially along the support shaft.
摘要翻译：传送链轮组件通常包括支撑轴，至少一个可滑动地接合支撑轴的传送链轮以及邻近输送链轮定位的邻接止挡件。抵靠止挡被构造成被移除以允许输送链轮沿着支撑轴轴向滑动。

47. 发明授权

US07999944B2 Multi-channel swept wavelength optical interrogation system and method for using same 失效
标题翻译：多通道扫波波长光询问系统及其使用方法
公开(公告)号：US07999944B2
公开(公告)日：2011-08-16
申请号：US12256852
申请日：2008-10-23
申请人： Stephen J. Caracci , Michael J. Dailey, Jr. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
发明人： Stephen J. Caracci , Michael J. Dailey, Jr. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
IPC分类号： G01N21/55
CPC分类号： G01N21/253 , G01N21/39 , G01N21/45
摘要： A multi-channel swept wavelength optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which for example could be located within the wells of a microplate. In one embodiment, the optical interrogation system comprises: (a) a tunable laser that emits an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; (b) a distribution unit that splits the optical beam into a plurality of interrogation beams; (c) an array of optical interrogation units that receive and direct the interrogation beams towards an array of biosensors; (d) the array of optical interrogation units receive a plurality of reflected interrogation beams from the array of biosensors; (e) a data processing device that receives and processes information associated with the reflected interrogation beams to determine for example whether or not there was a biochemical interaction on anyone of the biosensors.
摘要翻译：本文描述了多通道扫频波长光询问系统和方法，其能够询问一个或多个生物传感器，例如其可位于微板的孔内。在一个实施例中，光学询问系统包括：（a）可调激光器，其在预定时间段内发射具有预定的不同波长序列的光束; （b）分配单元，其将光束分成多个询问光束; （c）光学询问单元的阵列，其接收并将询问光束定向到生物传感器的阵列; （d）光学询问单元的阵列从生物传感器阵列接收多个反射询问光束; （e）数据处理装置，其接收和处理与所反映的询问光束相关联的信息，以确定例如生物传感器中任何一个生化交互是否存在。

48. 发明申请

US20090294262A1 LOW PROFILE ROTARY SWITCH WITH AN ENCLOSED DETENT SUB-ASSEMBLY 审中-公开
标题翻译：具有封装的子组件的低剖面旋转开关
公开(公告)号：US20090294262A1
公开(公告)日：2009-12-03
申请号：US12472031
申请日：2009-05-26
申请人： Donald Horton , William J. Miller
发明人： Donald Horton , William J. Miller
IPC分类号： H01H19/02
CPC分类号： H01H19/11 , H01H19/585
摘要： The panel mounted low profile rotary switch includes a knob, a detent sub-assembly, a shaft, a bushing, and a panel. The knob is held to the shaft by one or more locking screws and the operation of the detent sub-assembly is enclosed and is not altered by removal of the knob. The entire detent sub-assembly is located on the knob side or user's side of the panel. Only the bushing and the shaft extend through the panel. The shaft is connected to a rotary component such as a rotary switch contact which engages circuitry on a printed circuit board. The switch or electrical connection is located on the undersurface of the panel.
摘要翻译：面板安装的低轮廓旋转开关包括旋钮，制动子组件，轴，衬套和面板。旋钮通过一个或多个锁定螺钉保持在轴上，并且止动子组件的操作被封闭，并且不会通过移除旋钮而改变。整个定位子组件位于面板的旋钮侧或用户侧。只有套管和轴延伸穿过面板。轴连接到诸如旋转开关触点的旋转部件，其接合印刷电路板上的电路。开关或电气连接位于面板的下表面。

49. 发明授权

US07173966B2 Compensation for non-linear distortion in a modem receiver 有权
标题翻译：调制解调器接收机中非线性失真的补偿
公开(公告)号：US07173966B2
公开(公告)日：2007-02-06
申请号：US10842623
申请日：2004-05-10
申请人： William J. Miller
发明人： William J. Miller
IPC分类号： H03H7/30
CPC分类号： H04L27/3809 , H04K1/00 , H04L7/042 , H04L25/03159 , H04L25/03343 , H04L25/14 , H04L27/0004 , H04L27/2334 , H04L2025/03617 , H04L2025/03656
摘要： A method and modem receiver for receiving serial data from a transmission link, for recovering data from the received data, and for synchronizing the receiver timing to that of the transmitter are disclosed. A receiver equalizer includes a filter and quantizer in the forward path and a feedback circuit connecting the quantizer output to the filter input. A measuring circuit is used to initialize the feedback circuit. The receiver filter, provided as a QMF wavelet filter bank, is implemented in one embodiment with a form of polyphase filtering followed by four M/2-point FFTs. The quantizer recovers data symbols and provides a quantization error feedback signal. The measuring circuit provides an approximation of phase and amplitude of isolated wavelets.
摘要翻译：公开了一种用于从传输链路接收串行数据的方法和调制解调器接收器，用于从所接收的数据中恢复数据，并且用于使接收机定时与发射机的定时同步。接收机均衡器包括前向路径中的滤波器和量化器以及将量化器输出连接到滤波器输入端的反馈电路。测量电路用于初始化反馈电路。作为QMF小波滤波器组提供的接收机滤波器在一个实施例中以多相滤波的形式实现，随后是四个M / 2点FFT。量化器恢复数据符号并提供量化误差反馈信号。测量电路提供孤立小波的相位和幅度近似。

50. 发明授权

US06735264B2 Compensation for non-linear distortion in a modem receiver 有权
标题翻译：调制解调器接收机中非线性失真的补偿
公开(公告)号：US06735264B2
公开(公告)日：2004-05-11
申请号：US09943697
申请日：2001-08-31
申请人： William J. Miller
发明人： William J. Miller
IPC分类号： H04L2706
CPC分类号： H04L27/0004 , H04L25/03343 , H04L25/14
摘要： A method and modem for communicating serial input data over a transmission link are disclosed. Serial input data is partitioned into parallel data elements prior to rotation by an invertible linear mapping. Computationally efficient multi-rate wavelet filter banks are employed in a receiver for analyzing a received signal. Self-interference components are calculated in the receiver per sub-band and tap-weights for the filter banks are derived as a function over the range of self-interference values. A weighted sum is formed and subtracted from the delayed, received signal to eliminate the interference, and is removed from the recovered signal.
摘要翻译：公开了一种通过传输链路传送串行输入数据的方法和调制解调器。串行输入数据在通过可逆线性映射旋转之前被划分为并行数据元素。在接收机中采用计算效率高的多速率小波滤波器组来分析接收到的信号。在每个子带的接收机中计算自干扰分量，并且将滤波器组的抽头重量作为自干涉值范围的函数导出。形成加权和并从延迟的接收信号中减去加权和以消除干扰，并从恢复的信号中去除。

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