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41. 发明申请

US20110005669A1 METHOD OF MANUFACTURING HOLLOW MICRONEEDLE STRUCTURES 有权
标题翻译：制造中空微结构的方法
公开(公告)号：US20110005669A1
公开(公告)日：2011-01-13
申请号：US12635480
申请日：2009-12-10
申请人： Dae Sik LEE , Yong Sun Yoon , Moon Youn Jung , Seon Hee Park
发明人： Dae Sik LEE , Yong Sun Yoon , Moon Youn Jung , Seon Hee Park
IPC分类号： B05D7/00 , B05D3/12 , B32B38/00
CPC分类号： A61M37/0015 , A61B5/14514 , A61B5/685 , A61M2037/0053 , Y10T29/49885 , Y10T29/4998 , Y10T156/1062
摘要： Provided is a method of manufacturing a hollow microneedle structure. The method includes coating a hollow core having a predetermined section and being long in a lengthwise direction with a coating solution, and solidifying the coating solution to form a coating layer, depositing a metal seed layer on the coating layer, plating the seed metal layer with a metal to form a plated layer, cutting the hollow core having the plated layer at an inclination angle with respect to the lengthwise direction to form a surface inclination, and removing the hollow core and the coating layer to form a hollow. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. By use of the hollow core, the microneedle structure can have vertical microneedles with a uniform inner diameter.
摘要翻译：提供一种制造中空微针结构的方法。该方法包括用涂布溶液涂布具有预定部分并在长度方向上长的中空芯，并固化涂布溶液以形成涂层，在涂层上沉积金属籽晶层，将种子金属层与金属以形成镀层，切割具有相对于长度方向的倾斜角度的镀层的中空芯，以形成表面倾斜，并且移除中空芯和涂层以形成中空部。因此，可以制造中空微针结构以具有使疼痛最小化的直径，长度，硬度和倾斜角度。通过使用中空芯，微针结构可以具有均匀内径的垂直微针。

42. 发明授权

US07861575B2 Micro gas sensor and manufacturing method thereof 有权
标题翻译：微气体传感器及其制造方法
公开(公告)号：US07861575B2
公开(公告)日：2011-01-04
申请号：US12142695
申请日：2008-06-19
申请人： Chi Hoon Jun , Sang Choon Ko , Moon Youn Jung , Seon Hee Park
发明人： Chi Hoon Jun , Sang Choon Ko , Moon Youn Jung , Seon Hee Park
IPC分类号： G01N7/00 , G01N27/12
CPC分类号： G01N33/0027 , G01N27/128
摘要： A micro gas sensor is disclosed including a substrate; an open cavity formed in the substrate; an electrode pad separation groove formed on the substrate; a first and a second electrode pads formed over the substrate and electrically insulated from each other by the electrode pad separation groove; a micro heater connected to the first electrode pad and configured of a bridge structure suspended over the open cavity; a first sensing electrode extending from the first electrode pad and suspended over the open cavity; a second sensing electrode extending from the first electrode pad and suspended over the open cavity; and a gas sensing film electrically coupled to the micro heater and filling a gap between the first and the second sensing electrodes.
摘要翻译：公开了一种包括基板的微气体传感器; 在所述基板中形成的开放空腔; 形成在所述基板上的电极焊盘分离槽; 第一和第二电极焊盘，形成在所述衬底上并且由所述电极焊盘分离槽彼此电绝缘; 连接到第一电极焊盘并由悬挂在开放空腔上的桥结构构成的微加热器; 第一感测电极，其从所述第一电极焊盘延伸并悬挂在所述开放腔上; 第二感测电极，其从所述第一电极焊盘延伸并悬挂在所述开口腔上; 以及电气耦合到微加热器并填充第一和第二感测电极之间的间隙的气体感测膜。

43. 发明申请

US20100267127A1 POLYMERASE CHAIN REACTION APPARATUS 审中-公开
标题翻译：聚合物链反应装置
公开(公告)号：US20100267127A1
公开(公告)日：2010-10-21
申请号：US12484797
申请日：2009-06-15
申请人： Kwang Hyo CHUNG , Yo Han CHOI , JuHyun JEON , Moon Youn JUNG
发明人： Kwang Hyo CHUNG , Yo Han CHOI , JuHyun JEON , Moon Youn JUNG
IPC分类号： C12M1/02
CPC分类号： B01L7/525 , B01L3/5027 , B01L2200/028 , B01L2200/147 , B01L2300/0816 , B01L2300/088 , B01L2300/1805 , B01L2300/1827 , B01L2400/0445
摘要： Provided is a polymerase chain reaction (PCR) apparatus. A PCR is performed using the module assembly-type PCR apparatus. The module assembly-type PCR apparatus includes a first module, a second module, and a third module. A sample is provided to the first module. The second module provides different temperature ranges to the first module to generate thermal convection. The third module controls an operation of the second module. The first module is separably coupled to the second module. The second module is electrically separably coupled to the third module.
摘要翻译：提供了聚合酶链反应（PCR）装置。使用模块组装型PCR装置进行PCR。模块组装型PCR装置包括第一模块，第二模块和第三模块。样品提供给第一个模块。第二模块为第一模块提供不同的温度范围以产生热对流。第三模块控制第二模块的操作。第一模块可分离地耦合到第二模块。第二模块可电分离地耦合到第三模块。

44. 发明申请

US20100135965A1 METHOD OF CHONDROGENIC DIFFERENTIATION FROM MESENCHYMAL STEM CELL, AND COMPOSITION COMPRISING CHONDROGENIC CELL DIFFERENTIATED USING THE METHOD TO TREAT DISEASE CAUSED BY CARTILAGE DAMAGE 审中-公开
标题翻译：由细胞间质细胞分化的方法和包含使用方法治疗由损伤引起的疾病的方法分化的成纤维细胞的组合物
公开(公告)号：US20100135965A1
公开(公告)日：2010-06-03
申请号：US12471570
申请日：2009-05-26
申请人： Min-Suk Jeong , Moon-Youn Jung , Seon-Hee Park
发明人： Min-Suk Jeong , Moon-Youn Jung , Seon-Hee Park
IPC分类号： A61K35/12 , C12N5/06 , C12N5/08
CPC分类号： C12N5/0655 , A61K35/12 , C12N2525/00
摘要： Provided are a method of chondrogenic differentiation from mesenchymal stem cells and a composition comprising chondrogenic cells differentiated using the method to treat diseases caused by cartilage damage. In the method, a centrifugal force is applied to human mesenchymal stem cells to be differentiated into chondrogenic cells. The chondrogenic differentiation may be achieved at moderate cost without using expensive cytokines or growth factors by periodically applying only a centrifugal force. According to the method of chondrogenic differentiation from mesenchymal stem cells in the present embodiment, chondrogenic cells may be also differentiated from human mesenchymal stem cells.
摘要翻译：提供了一种从间充质干细胞分化软骨形成的方法，以及包含软骨细胞的组合物，其使用用于治疗由软骨损伤引起的疾病的方法分化。在该方法中，将离心力施加于人间充质干细胞以分化为软骨形成细胞。软骨形成分化可以以适中的成本实现，而不需要通过周期性地施加离心力而不使用昂贵的细胞因子或生长因子。根据本实施方式的间充质干细胞的软骨形成分化方法，软骨形成细胞也可以与人间充质干细胞分化。

45. 发明申请

US20090120865A1 DISPOSABLE MULTI-LAYERED FILTRATION DEVICE FOR THE SEPARATION OF BLOOD PLASMA 有权
标题翻译：用于分离血浆等离子体的多层过滤装置
公开(公告)号：US20090120865A1
公开(公告)日：2009-05-14
申请号：US12133295
申请日：2008-06-04
申请人： Kwang Hyo Chung , Yo Han Choi , Dae Sik Lee , Ju Hyun Jeon , Moon Youn Jung , Seon Hee Park
发明人： Kwang Hyo Chung , Yo Han Choi , Dae Sik Lee , Ju Hyun Jeon , Moon Youn Jung , Seon Hee Park
IPC分类号： B01D25/12 , B01D27/08 , B01D35/30
CPC分类号： G01N33/491 , B01L3/502753 , B01L2300/043 , B01L2300/0645 , B01L2300/0681 , B01L2300/0825 , B01L2300/0887 , B01L2400/0406 , B33Y80/00
摘要： Provided is a disposable multi-layered filtration device for the separation of blood plasma which can be applied to a biochip and appropriate for disposal uses. The filtration device for the separation of blood plasma includes: an upper substrate including a blood inlet; an intermediate substrate including a filtering unit for extracting blood plasma from blood flowing through the blood inlet; and a lower substrate including an air outlet, wherein the upper substrate, the intermediate substrate, and the lower substrate are stacked and adhered.
摘要翻译：提供了一种用于分离血浆的一次性多层过滤装置，其可以应用于生物芯片并适合于处置用途。用于分离血浆的过滤装置包括：包括血液入口的上基板; 中间基板，包括用于从流过血液入口的血液中提取血浆的过滤单元; 以及包括空气出口的下基板，其中所述上基板，所述中间基板和所述下基板被堆叠和粘附。

46. 发明授权

US06951708B2 Method of forming photosensitive film pattern 失效
标题翻译：形成感光膜图案的方法
公开(公告)号：US06951708B2
公开(公告)日：2005-10-04
申请号：US10704624
申请日：2003-11-12
申请人： Moon Youn Jung , Chi Hoon Jun
发明人： Moon Youn Jung , Chi Hoon Jun
IPC分类号： H01L21/027 , G03C7/00 , G03C7/20 , G03F7/00 , G03F7/16 , G03F7/20
CPC分类号： B81C1/00492 , G03F7/0035 , G03F7/161
摘要： The present invention relates to a method of forming a photosensitive film pattern. It provides a method of forming a photosensitive film pattern capable of performing a photolithography process by blocking an opening of a high aspect ratio trench with a DFR film, during forming a semiconductor element and an MEMS element. In addition, it is possible to prevent the photoresist from flowing into the trench when the liquid photoresist is deposited by a spin coating method to form the photosensitive film pattern for metal pattern to apply electric signal from outside to inside of trench.
摘要翻译：本发明涉及形成感光膜图案的方法。它提供了一种在形成半导体元件和MEMS元件期间形成能够通过用DFR膜阻挡高纵横比沟槽的开口来进行光刻工艺的感光膜图案的方法。此外，当通过旋涂方法沉积液态光致抗蚀剂以形成用于金属图案的感光膜图案以从外部到沟槽内部施加电信号时，可以防止光致抗蚀剂流入沟槽。

47. 发明授权

US06922270B2 Multi-step landing micro-mirror, method for manufacturing the same and multi-step landing micro-mirror array 有权
标题翻译：多步登陆微镜，制造相同和多步登陆微镜阵列的方法
公开(公告)号：US06922270B2
公开(公告)日：2005-07-26
申请号：US10735669
申请日：2003-12-16
申请人： Moon Youn Jung , Chi Hoon Jun , Chang Auck Choi , Yun Tae Kim
发明人： Moon Youn Jung , Chi Hoon Jun , Chang Auck Choi , Yun Tae Kim
IPC分类号： B81B3/00 , G02B26/08
CPC分类号： G02B26/0841 , B81B3/0062 , B81B2201/042 , Y10S359/904
摘要： A multi-step landing micro-mirror, a method for manufacturing the same, and a multi-step landing micro-mirror array are disclosed. The multi-step landing micro-mirror comprises a trench formed in a substrate and having N−1 steps in one side wall thereof; N plates rotated in or on the trench; and 2N springs for connecting the plates to each other; wherein the N plates are composed of an outermost first plate, a second plate connected with the first plate by the spring and located in the first plate, . . . , and a N-th plate connected with a (N−1)-th plate by the spring and located in the (N−1)-th plate, wherein when voltages are applied to the N plates and the trench, respectively, the first plate is subjected to a first landing with a predetermined rotation angle on a first step of the trench due to the constant voltage, the second plate is subjected to a second landing with the predetermined rotation angle on a second step of the trench, . . . , the N-th plate is subjected to a N-th landing with the predetermined rotation angle on the other side wall of the trench. Accordingly, the low voltage driving can be performed by performing the multi-step driving during the electrostatic force is applied, the elastic force of the spring for supporting the mirror can be enhanced, therefore the reliability of the optical switch can be improved.
摘要翻译：公开了一种多步着陆微镜，其制造方法以及多台阶着陆微镜阵列。多台阶着陆微反射镜包括形成在基板中并在其一个侧壁中具有N-1个台阶的沟槽; N个板在沟槽中或沟槽上旋转; 和2N弹簧，用于将板彼此连接; 其中所述N个板由最外面的第一板，通过弹簧与所述第一板连接并位于所述第一板中的第二板组成。。。以及通过弹簧与第（N-1）板连接并位于（N-1）板中的第N板，其中当分别向N个板和沟槽施加电压时，第一板由于恒定的电压在沟槽的第一台阶上以预定的旋转角度进行第一次着陆，第二板在沟槽的第二台阶上以预定的旋转角进行第二次着陆。。。第N个板在沟槽的另一个侧壁上以预定的旋转角进行第N次着陆。因此，通过在施加静电力的同时进行多级驱动，可以进行低压驱动，可以提高用于支撑反射镜的弹簧的弹力，从而可以提高光开关的可靠性。

48. 发明申请

US20130236885A1 MULTIPLE SEPARATION DEVICE AND METHOD OF SEPARATING BLOOD CANCER CELL 有权
标题翻译：多分离装置和分离血液癌细胞的方法
公开(公告)号：US20130236885A1
公开(公告)日：2013-09-12
申请号：US13787725
申请日：2013-03-06
申请人： Seong-Mok CHO , Dae-Sik LEE , Jeong Won PARK , Moon Youn JUNG
发明人： Seong-Mok CHO , Dae-Sik LEE , Jeong Won PARK , Moon Youn JUNG
IPC分类号： G01N1/34
CPC分类号： G01N1/34 , G01N33/54326 , G01N33/54386 , G01N33/57488
摘要： The present inventive concept provides a multiple separation device and a method of separating a blood cancer cell using the same. In the device and the method, a blood sample is put in a fine channel and then cancer cells can be separated according to the type of cancer by controlling a flow velocity of the blood or a magnetic force of ferromagnetic pattern.
摘要翻译：本发明构思提供了多个分离装置和使用其分离血液细胞的方法。在装置和方法中，将血液样品置于细孔中，然后通过控制血液的流速或铁磁图案的磁力，根据癌症的类型分离癌细胞。

49. 发明申请

US20130161533A1 BIOCHIP ANALYSIS DEVICE 审中-公开
标题翻译：生物分析装置
公开(公告)号：US20130161533A1
公开(公告)日：2013-06-27
申请号：US13615073
申请日：2012-09-13
申请人： Dong-Ho SHIN , Moon Youn Jung
发明人： Dong-Ho SHIN , Moon Youn Jung
IPC分类号： G02F1/01 , G01N21/64
CPC分类号： G01N21/6452 , G01N21/6454 , G01N2021/6471
摘要： Disclosed is a biochip analysis device which includes first and second spatial light modulators; and a spatial light modulation driver configured to drive the first and second spatial light modulators, wherein the first spatial light modulator varies a wavelength of light to be irradiated to a biochip in response to a control of the spatial light modulation driver and the spatial light modulator passes a fluorescence signal selected from fluorescence signals generated by the biochip in response to a control of the spatial light modulation driver.
摘要翻译：公开了一种生物芯片分析装置，其包括第一和第二空间光调制器; 以及空间光调制驱动器，被配置为驱动第一和第二空间光调制器，其中响应于空间光调制驱动器和空间光调制器的控制，第一空间光调制器改变要照射到生物芯片的光的波长响应于空间光调制驱动器的控制，传递从生物芯片产生的荧光信号中选择的荧光信号。

50. 发明申请

US20120162643A1 METHOD AND APPARATUS FOR MEASURING SIZE OF MICROPARTICLES 失效
标题翻译：测量微量元素大小的方法和装置
公开(公告)号：US20120162643A1
公开(公告)日：2012-06-28
申请号：US13289396
申请日：2011-11-04
申请人： Hyeon-Bong PYO , Moon Youn JUNG
发明人： Hyeon-Bong PYO , Moon Youn JUNG
IPC分类号： G01J3/28 , G01N15/02
CPC分类号： G01N15/0205
摘要： A method for measuring the size of microparticles includes: measuring an extinction spectrum of a medium having microparticles dispersed therein; and calculating average size of the microparticles based on the measured extinction spectrum and the Mie scattering theory.
摘要翻译：测定微粒尺寸的方法包括：测定其中分散有微粒的介质的消光谱; 并基于测得的消光谱和米氏散射理论计算微粒的平均尺寸。

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