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31. 发明申请

US20130189771A1 CELL CULTURE DEVICE 审中-公开
标题翻译：细胞培养装置
公开(公告)号：US20130189771A1
公开(公告)日：2013-07-25
申请号：US13358014
申请日：2012-01-25
申请人： Hans Strandberg , Lars Enochson , Joakim Sandstedt
发明人： Hans Strandberg , Lars Enochson , Joakim Sandstedt
IPC分类号： C12M1/00
CPC分类号： C12M35/02
摘要： A cell culture device has a chamber bottom, a wall section and a lid that enclose a culture chamber. A first electrode in the chamber bottom extends over a cell culture area of the culture chamber onto which cells are to be cultured. A second electrode in the lid is aligned with the first electrode and extends over an area in the lid corresponding to the cell culture area. A stimulation pulse generator applies stimulation pulses over the electrodes to form an electric field with a homogenous current density in the cell culture area.
摘要翻译：细胞培养装置具有包围培养室的腔室底部，壁部分和盖子。腔室底部的第一个电极延伸到要培养细胞的培养室的细胞培养区域上。盖子中的第二电极与第一电极对准，并延伸到对应于细胞培养区域的盖子中的一个区域上。刺激脉冲发生器在电极上施加刺激脉冲，以在细胞培养区域中形成均匀电流密度的电场。

32. 发明授权

US08140161B2 Method and medical system for determining a link quality of a communication link in such a medical system 有权
标题翻译：用于确定这种医疗系统中的通信链路的链路质量的方法和医疗系统
公开(公告)号：US08140161B2
公开(公告)日：2012-03-20
申请号：US12515341
申请日：2006-11-16
申请人： Mark Willerton , Viktor Skoog , Hans Strandberg , Lars Forsmark
发明人： Mark Willerton , Viktor Skoog , Hans Strandberg , Lars Forsmark
IPC分类号： A61N1/00
CPC分类号： A61N1/3706 , A61N1/37235 , A61N1/37252 , A61N1/37276 , H04L1/0045 , H04L1/20
摘要： In a method and medical system for determining a link quality and a link quality margin of a communication link between a programmer device and an implantable medical device of such a medical system, a link quality monitoring circuit of the programmer or the medical device a present link quality and/or link quality margin at reduced signal power using at least one link quality parameter.
摘要翻译：在用于确定编程器装置和这种医疗系统的可植入医疗装置之间的通信链路的链路质量和链路质量裕度的方法和医疗系统中，程序员或医疗装置的链路质量监测电路本地链路使用至少一个链路质量参数降低信号功率的质量和/或链路质量裕度。

33. 发明申请

US20100280563A1 DEVICE AND METHOD FOR DETECTING AND TREATING A MYOCARDIAL INFARCTION USING PHOTOBIOMODULATION 审中-公开
标题翻译：检测和治疗使用光合作用的心肌梗塞的装置和方法
公开(公告)号：US20100280563A1
公开(公告)日：2010-11-04
申请号：US12528363
申请日：2007-02-28
申请人： Anne Norlin-Weissenrieder , Leda Henriquez , Hans Strandberg , Eva Hartström , Mikael Sjögren , Annika Naeslund , Johan Eckerdal
发明人： Anne Norlin-Weissenrieder , Leda Henriquez , Hans Strandberg , Eva Hartström , Mikael Sjögren , Annika Naeslund , Johan Eckerdal
IPC分类号： A61N1/362
CPC分类号： A61N1/36521 , A61B5/0422 , A61B5/0452 , A61B5/053 , A61B5/6846 , A61B5/7239 , A61N1/36557 , A61N1/3702 , A61N5/0601 , A61N2005/063 , A61N2005/0652 , A61N2005/0659 , A61N2005/067
摘要： In an implantable medical device and a method for treating cardiac tissue of a heart of a patient with therapeutic light, a myocardial infarction is detected and a location the myocardial infarction is identified. A therapy session is initiated by selectively activating one or more of a number of light emitting units arranged in at least one medical lead connectable to the implantable medical device, to emit therapeutic light toward the detected location of the myocardial infarction upon detection of an occurrence of the myocardial infarction.
摘要翻译：在可植入医疗装置和用治疗光治疗患者心脏的心脏组织的方法中，检测到心肌梗塞并确定心肌梗塞的位置。通过选择性地激活布置在可连接到可植入医疗装置的至少一个医疗引线中的多个发光单元中的一个或多个来发起治疗会话，以便在检测到发生心肌梗死的发生时向被检测的心肌梗死位置发射治疗光心肌梗塞。

34. 发明申请

US20100121413A1 METHOD AND MEDICAL SYSTEM FOR DETERMINING A LINK QUALITY OF A COMMUNICATION LINK IN SUCH A MEDICAL SYSTEM 有权
标题翻译：用于确定这种医疗系统中的通信链路的链路质量的方法和医疗系统
公开(公告)号：US20100121413A1
公开(公告)日：2010-05-13
申请号：US12515341
申请日：2006-11-16
申请人： Mark Willerton , Viktor Skoog , Hans Strandberg , Lars Forsmark
发明人： Mark Willerton , Viktor Skoog , Hans Strandberg , Lars Forsmark
IPC分类号： A61N1/08
CPC分类号： A61N1/3706 , A61N1/37235 , A61N1/37252 , A61N1/37276 , H04L1/0045 , H04L1/20
摘要： In a method and medical system for determining a link quality and a link quality margin of a communication link between a programmer device and an implantable medical device of such a medical system, a link quality monitoring circuit of the programmer or the medical device a present link quality and/or link quality margin at reduced signal power using at least one link quality parameter.
摘要翻译：在用于确定编程器装置和这种医疗系统的可植入医疗装置之间的通信链路的链路质量和链路质量裕度的方法和医疗系统中，程序员或医疗装置的链路质量监测电路本地链路使用至少一个链路质量参数降低信号功率的质量和/或链路质量裕度。

35. 发明申请

US20080269822A1 Device for Evaluating Positions of an Implantable Medical Device 审中-公开
标题翻译：用于评估植入式医疗装置的位置的装置
公开(公告)号：US20080269822A1
公开(公告)日：2008-10-30
申请号：US11666960
申请日：2004-11-02
申请人： Karin Ljungstrom , Anders Bjorling , Hans Strandberg
发明人： Karin Ljungstrom , Anders Bjorling , Hans Strandberg
IPC分类号： A61N1/368
CPC分类号： A61N1/372 , A61B5/029 , A61B5/0452 , A61N1/08
摘要： In a device and method for evaluating positions of a medical lead during an implantation procedure, an IEGM signal and a signal indicative of heart pumping activity are obtained for each of a number of different lead positions, and those signals are stored dependent on the different lead positions. A processor automatically determines a lead position, from among the stored lead positions, that results in most favorable hemodynamics of the heart, based on the IEGM signal and the pumping activity signal.
摘要翻译：在用于评估植入程序期间医疗引线位置的装置和方法中，针对多个不同引导位置的每一个获得指示心脏泵送活动的IEGM信号和信号，并且这些信号取决于不同的引线职位基于IEGM信号和泵送活动信号，处理器根据存储的引导位置自动确定导致心脏最有利的血液动力学的引导位置。

36. 发明授权

US07085602B2 Implantable bi-ventricular stimulation device and system, and bi-ventricular stimulation and sensing method 有权
标题翻译：可植入双心室刺激装置和系统，以及双心室刺激和感测方法
公开(公告)号：US07085602B2
公开(公告)日：2006-08-01
申请号：US10720449
申请日：2003-11-24
申请人： Sven-Erik Hedberg , Asa Uhrenius , Karin Jarverud , Hans Strandberg , Nils Holmström , Anders Björling , Göran Budgifvars
发明人： Sven-Erik Hedberg , Asa Uhrenius , Karin Jarverud , Hans Strandberg , Nils Holmström , Anders Björling , Göran Budgifvars
IPC分类号： A61N1/365
CPC分类号： A61N1/368 , A61N1/056 , A61N1/3684 , A61N2001/0585
摘要： An implantable bi-ventricular heart stimulating device (10) has a control circuit with first and second sensing circuits for respectively sensing in the two ventricles and first and second stimulation circuits for respectively stimulating the two ventricles. The control circuit determines whether a signal, sensed by said second sensing circuit, occurs essentially simultaneously with a signal sensed by the first sensing circuit. Furthermore, the control circuit determines whether a further signal is sensed by said second sensing circuit within a predetermined time interval which follows after the signal sensed by the second sensing circuit but within the same time cycle as that signal. If this occurs, the control circuit determines whether the sensed signals represent actual cardiac events, or are likely the result of far field detection.
摘要翻译：可植入式双心室心脏刺激装置（10）具有控制电路，该控制电路具有用于分别感测两个心室的第一和第二感测电路以及分别刺激两个脑室的第一和第二刺激电路。控制电路确定由所述第二感测电路检测到的信号是否基本上与由第一感测电路感测的信号同时发生。此外，控制电路确定在由第二感测电路感测到的信号之后但在与该信号相同的时间周期内的预定时间间隔内，所述第二感测电路是否感测到另外的信号。如果发生这种情况，则控制电路确定感测到的信号是否代表实际的心脏事件，或者很可能是远场检测的结果。

37. 发明申请

US20060074455A1 Implantable medical device 有权
标题翻译：植入式医疗器械
公开(公告)号：US20060074455A1
公开(公告)日：2006-04-06
申请号：US10528671
申请日：2003-06-23
申请人： Hans Strandberg
发明人： Hans Strandberg
IPC分类号： A61N1/362
CPC分类号： A61N1/37252
摘要： An implantable medical device is operable in a normal mode of operation, including a test mode, as well as in at least one other mode of operation outside of the normal mode. The device has a signal detector that is responsive to an external activation and a timer that can be programmed with a specified time period. If the external activation is detected by the signal detector during the programmed time period, the medical device is operated in a mode outside of the normal mode. The medical device enters into the test mode, within the normal mode, if the external activation is detected by the signal detector outside of the time period.
摘要翻译：可植入医疗装置可以在通常的操作模式中操作，包括测试模式，以及在正常模式之外的至少一种其他操作模式。该装置具有响应于外部激活的信号检测器和可以在指定时间段内编程的定时器。如果在编程的时间段期间由信号检测器检测到外部激活，则医疗设备在正常模式之外的模式下操作。如果在时间段之外的信号检测器检测到外部激活，医疗设备进入测试模式，在正常模式下。

38. 发明授权

US06188928B1 Apparatus for tissue stimulation 失效
标题翻译：组织刺激装置
公开(公告)号：US06188928B1
公开(公告)日：2001-02-13
申请号：US09308077
申请日：1999-07-22
申请人： Kjell Norén , Jakub Hirschberg , Hans Strandberg
发明人： Kjell Norén , Jakub Hirschberg , Hans Strandberg
IPC分类号： A61N137
CPC分类号： A61N1/3712 , A61N1/3716
摘要： Mathematical functions such as recursive autoregression models which include parameters are used for defining the heart signal and any signals disturbing the heart signal, such as polarization signals. By registering, during a predetermined time interval, the electrode signal for determining the parameters for one or more different mathematical functions, the parameters can be used on their own or in combination to determine the activity of the heart, i.e., whether the registered electrode signal corresponds to a stimulated, spontaneous or absence of heart activity.
摘要翻译：诸如包括参数的递归自回归模型的数学函数用于定义心脏信号和干扰心脏信号的任何信号，例如偏振信号。通过在预定时间间隔内登记用于确定一个或多个不同数学函数的参数的电极信号，可以单独或组合使用这些参数以确定心脏的活动，即，是否注册的电极信号对应于刺激，自发或不存在心脏活动。

39. 发明授权

US6097983A Cardiac event detecting system for a heart stimulator 有权
标题翻译：用于心脏刺激器的心脏事件检测系统
公开(公告)号：US6097983A
公开(公告)日：2000-08-01
申请号：US192301
申请日：1998-11-17
申请人： Hans Strandberg
发明人： Hans Strandberg
IPC分类号： A61B5/0452 , A61B5/046 , A61N1/368
CPC分类号： A61B5/0452 , A61N1/368 , A61B5/046 , A61B5/7239
摘要： A cardiac event detecting system for an implantable heart stimulator intended to be connected to the heart of a patient through at least two unipolar electrode leads or at least one bipolar electrode lead having one electrode pole in the atrium and one electrode pole in the ventricle for sensing heart signals, has at least two signal channels for signals sensed between the two electrode poles and between one of the electrode poles and the stimulator capsule, respectively. Each signal channel has a signal processing stage. Decision logic compares the signals from the two signal channels with signal criteria for detecting the occurrence of a cardiac event. An A/D-convertor converts sampled values of the sensed heart signals into digital words for each signal channel. The decision logic is adapted for comparing the digital words and their differences with the criteria for determining the occurrence of a cardiac event.
摘要翻译：一种用于可植入心脏刺激器的心脏事件检测系统，其旨在通过至少两个单极电极引线或至少一个在心房中具有一个电极极的一个双极电极引线和心室中的一个电极极连接到患者的心脏，用于感测心脏信号具有至少两个信号通道，用于在两个电极之间以及在一个电极和刺激器胶囊之间感测的信号。每个信号通道具有信号处理级。决定逻辑将来自两个信号通道的信号与用于检测心脏事件的发生的信号标准进行比较。 A / D转换器将感测到的心脏信号的采样值转换成每个信号通道的数字字。决定逻辑适于将数字词及其差异与用于确定心脏事件的发生的标准进行比较。

40. 发明授权

US4541430A Method and a heart pacemaker for terminating a tachycardia 失效
标题翻译：方法和用于终止心动过速的心脏起搏器
公开(公告)号：US4541430A
公开(公告)日：1985-09-17
申请号：US546457
申请日：1983-10-28
申请人： Hakan Elmqvist , Hans Strandberg
发明人： Hakan Elmqvist , Hans Strandberg
IPC分类号： A61N1/365 , A61N1/362 , A61N1/372 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3621
摘要： A routine is provided in order to be able to terminate a detected tachycardia quickly and reliably, the routine generating a sequence of n stimulation pulses, checking the heart reaction and, under given conditions, changing the sequence until the sequence terminates the tachycardia. The effective sequences are stored in a plurality of registers and are employed in a prescribable order for controlling the stimulation pulses. In addition to the traditional electronics, a heart pacemaker for the implementation of this method contains a tachycardia detector, a memory having N registers for the sequences to be stored, as well as a control logic for the selection of the registers and/or for changing the register values.
摘要翻译：提供了一种例程，以便能够快速可靠地终止检测到的心动过速，例程产生n个刺激脉冲序列，检查心脏反应，并且在给定条件下，改变序列直到序列终止心动过速。有效序列存储在多个寄存器中，并以可规定的顺序被用于控制刺激脉冲。除了传统的电子设备之外，用于实施该方法的心脏起搏器还包括心动过速检测器，具有用于存储的序列的N个寄存器的存储器，以及用于选择寄存器和/或用于改变的控制逻辑寄存器值。

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