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21. 发明授权

US08282598B2 External anchoring configurations for modular gastrointestinal prostheses 有权
标题翻译：模块化胃肠假体的外部锚定配置
公开(公告)号：US08282598B2
公开(公告)日：2012-10-09
申请号：US12833605
申请日：2010-07-09
申请人： Kedar R. Belhe , Paul J. Thompson
发明人： Kedar R. Belhe , Paul J. Thompson
IPC分类号： A61M39/00
CPC分类号： A61F5/0076 , A61F5/003
摘要： Components may be used separately or in combination to create anchoring systems for intra-luminal implants for the treatment of metabolic disorders such as obesity and diabetes. Various systems include an external component adapted for deployment around a portion of the gastrointestinal tract (e.g., the duodenum) and an internal component adapted for implantation within the gastrointestinal tract. Various systems use anchors that are based on mechanical interference, elasticity, spring force, shape memory transformation, magnetic attraction, repulsion and/or levitation. Various embodiments rely on longitudinal anchoring of the implants with minimal force against tissue.
摘要翻译：组分可以单独使用或组合使用以产生腔内植入物用于治疗代谢紊乱如肥胖症和糖尿病的锚定系统。各种系统包括适于部署在胃肠道的一部分（例如，十二指肠）周围的外部部件和适于植入胃肠道内部的内部部件。各种系统使用基于机械干涉，弹性，弹簧力，形状记忆变换，磁吸引，排斥和/或悬浮的锚。各种实施例依赖于对组织的最小力的植入物的纵向锚固。

22. 发明授权

US08007527B2 Stent with dual support structure 有权
标题翻译：支架双支撑结构
公开(公告)号：US08007527B2
公开(公告)日：2011-08-30
申请号：US12633246
申请日：2009-12-08
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2230/0013 , A61F2230/0054 , A61F2250/001
摘要： A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
摘要翻译：管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。管包括在第一和第二端之间延伸的结构梁。当管从未展开的直径变大到扩大的直径时，结构梁从第一几何变化到第二几何形状。结构梁包括第一和第二纵向元件，每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。当管从未展开的直径改变到扩大的直径时，所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状，以使间隔保持基本上不变，因为管从未展开的直径变大到扩大的直径直径。

23. 再颁专利

USRE40122E1 Expandable stent-graft covered with expanded polytetrafluoroethylene 有权
标题翻译：可扩展的支架移植物覆盖有膨胀的聚四氟乙烯
公开(公告)号：USRE40122E1
公开(公告)日：2008-02-26
申请号：US11067620
申请日：2005-02-25
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/06
CPC分类号： B29C55/22 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2210/0057 , A61F2230/0078 , A61F2250/0028 , A61F2250/0039 , A61F2250/0063 , A61L31/10 , B29D23/001 , B29K2027/18 , B29K2995/0051 , B29K2995/0053 , C08L27/18
摘要： The expandable stent-graft generally defines a cylindrical lumen made from a stent having a discontinuous wall that is at least substantially covered with an expended polytetrafluoroethylene material. The expanded polytetrafluoroethylene covering may be a biaxially oriented, expanded polytetrafluoroethylene material having nodules and longitudinal and circumferential fibrils or a uniaxially oriented, expanded polytetrafluoroethylene material. The expandable stent-graft expands and compresses in association with the stent structure as it is contracted and expanded.
摘要翻译：可扩张的支架移植物通常限定由支架制成的圆柱形内腔，所述支架具有至少基本被消耗的聚四氟乙烯材料覆盖的不连续壁。膨胀聚四氟乙烯覆盖物可以是具有结节和纵向和周向纤维的双轴取向膨胀聚四氟乙烯材料或单轴取向的膨胀聚四氟乙烯材料。随着支架结构的缩小和膨胀，可扩张的支架移植物与支架结构相关联地膨胀和压缩。

24. 发明授权

US06749627B2 Grip for stent delivery system 有权
标题翻译：夹持支架输送系统
公开(公告)号：US06749627B2
公开(公告)日：2004-06-15
申请号：US09765721
申请日：2001-01-18
申请人： Paul J. Thompson , Thomas M. Benson
发明人： Paul J. Thompson , Thomas M. Benson
IPC分类号： A61F206
CPC分类号： A61F2/95 , A61B17/2909 , A61F2002/9517 , A61M2025/09116 , A61M2025/09125
摘要： A stent delivery system includes inner and outer tubular members with the outer tubular member sized to pass through the body lumen to the deployment site and with the inner tubular member sized to be received within the outer tubular member. The inner and outer tubular members are axially slideable relative to one another between a transport position and a deploy position. The inner tubular member has a stent attachment location at its distal end. The stent attachment location is covered by the outer tubular member when the inner and outer tubular members are in the transport position. The stent attachment location is exposed when the inner and outer tubular members are in the deploy position. A first handle is provided rotatably connected to a proximal end of the outer tubular member for the first handle to transmit to the outer tubular member axial forces applied to the handle by an operator and to rotate freely about the axis relative to the outer tubular member.
摘要翻译：支架输送系统包括内部和外部管状构件，外部管状构件的尺寸设计成穿过体腔到达展开位置，并且内部管状构件的尺寸设置成容纳在外部管状构件内。内部和外部管状构件在运输位置和展开位置之间可相对于彼此轴向滑动。内部管状构件在其远端具有支架附接位置。当内部和外部管状构件处于运输位置时，支架附接位置被外部管状构件覆盖。当内部和外部管状构件处于展开位置时，支架附接位置被暴露。第一手柄设置成可旋转地连接到外部管状构件的近端，用于第一手柄，以便通过操作者向外部管状构件传递施加到手柄的轴向力，并相对于外部管状构件绕该轴线自由旋转。

25. 发明授权

US06558415B2 Stent 有权
标题翻译：支架
公开(公告)号：US06558415B2
公开(公告)日：2003-05-06
申请号：US09765725
申请日：2001-01-18
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/89 , A61F2002/91508 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0014 , A61F2230/0013 , A61F2230/0054 , A61F2250/0036
摘要： The present disclosure relates to a stent including a stent body having a stent axis. The stent body includes structural members defining openings through the stent body. The structural members are provided with regions having different widths. The relative sizes of the widths are selected to control the length of the stent body as the stent body is radially expanded from an un-deployed orientation to a deployed orientation. In one embodiment, the regions having different widths are provided by tapering the widths of selected segments of the structural member.
摘要翻译：本公开涉及一种支架，其包括具有支架轴线的支架主体。支架主体包括限定通过支架主体的开口的结构构件。结构构件设置有具有不同宽度的区域。选择宽度的相对尺寸来控制支架主体的长度，因为支架主体从未展开的方位向展开方向径向展开。在一个实施例中，具有不同宽度的区域通过使结构构件的选定段的宽度变窄来提供。

26. 发明授权

US06273876B1 Catheter segments having circumferential supports with axial projection 有权
标题翻译：导管段具有轴向突出的周向支撑
公开(公告)号：US06273876B1
公开(公告)日：2001-08-14
申请号：US09185769
申请日：1998-11-03
申请人： Daniel J. Klima , Paul J. Thompson , Robert M. Vidlund
发明人： Daniel J. Klima , Paul J. Thompson , Robert M. Vidlund
IPC分类号： A61M500
CPC分类号： A61M25/0051 , A61M25/005 , A61M25/0054
摘要： The present disclosure relates to a segment of catheter having a longitudinal axis extending between distal and proximal ends of the catheter segment. The segment includes a plurality of circumferential supports surrounding the longitudinal axis. The segment also includes axially members connected to the circumferential supports. The axial members extend in the direction generally along the longitudinal axis. The axial members include three ends that are positioned between the circumferential supports.
摘要翻译：本公开涉及具有在导管段的远端和近端之间延伸的纵向轴线的导管段。该段包括围绕纵向轴线的多个周向支撑件。该段还包括连接到周向支撑件的轴向构件。轴向构件沿着大致沿着纵向轴线的方向延伸。轴向构件包括位于周向支撑件之间的三个端部。

27. 发明授权

US06193748B1 Occlusion device 有权
标题翻译：闭塞装置
公开(公告)号：US06193748B1
公开(公告)日：2001-02-27
申请号：US09332284
申请日：1999-06-11
申请人： Paul J. Thompson , Claude Clerc
发明人： Paul J. Thompson , Claude Clerc
IPC分类号： A61F200
CPC分类号： A61B17/12109 , A61B17/12022 , A61B17/12172
摘要： The present invention is an occlusion device adapted for implantation into a fluid flow-supporting body lumen. The occlusion device comprises a flexible support structure and a flexible fluid flow-occluding membrane that is positioned concentric with the flexible support structure. The support structure is formed from a plurality of interwoven filaments that form an axially flexible and radially compressible structure that, in its expanded state, engages the lumen. The membrane generally includes a constricted region and constriction means, such as a mechanical seal, for closing the membrane at one end. The membrane is formed from a plurality of filaments, and in one embodiment, the membrane filaments are tightly interbraided with the structure filaments to form the occlusion device. Alternatively, the membrane is separately fabricated of interwoven filaments, and is positioned either within the support structure or without the structure so as to surround the support structure.
摘要翻译：本发明是一种适于植入流体流动支撑体腔内的闭塞装置。闭塞装置包括柔性支撑结构和与柔性支撑结构同心定位的柔性流体阻流膜。支撑结构由多个交织的长丝形成，其形成轴向柔性且可径向压缩的结构，其在其膨胀状态下与内腔接合。膜通常包括用于在一端封闭膜的收缩区域和收缩装置，例如机械密封。膜由许多细丝形成，在一个实施方案中，膜丝与结构细丝紧密接触以形成遮挡装置。或者，膜分开地由交织的长丝制成，并且被定位在支撑结构内或不包括结构以包围支撑结构。

28. 发明授权

US5758562A Process for manufacturing braided composite prosthesis 失效
标题翻译：编织复合假体的制造工艺
公开(公告)号：US5758562A
公开(公告)日：1998-06-02
申请号：US640062
申请日：1996-04-30
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61B19/00 , A61F2/00 , A61F2/06 , A61F2/90 , A61L27/00 , D04C1/06 , D04C1/00
CPC分类号： A61F2/06 , A61F2/90 , A61F2/95 , D04C1/06 , A61B90/39 , A61F2/07 , A61F2002/072 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2240/001 , D10B2509/06
摘要： A process is disclosed for manufacturing a prothesis for intraluminal implantation. The prosthesis is formed with a flexible tubular interbraided structure of metal or polymeric monofilaments, and polymeric multifilament yarns, and can be elastically deformed to reduce its diameter through axial elongation. The monofilaments and multifilament yarns are wound on a mandrel arranged in axially spaced apart helices, concentric on a common central axis of the prosthesis. The monofilaments are selectively shaped before their interbraiding with the multifilament yarns, either by an age-hardening or other heat-setting stage while wound on a mandrel, or by a cold-working stage that controllably plastically deforms the strands. The shaped structural strands cooperate to impart to the prosthesis its nominal shape and resilience. The textile strands are interbraided with the structural strands to provide a sheeting that occupies interstices between adjacent structural strands, to reduce permeability and thereby enhance the utility of the prosthesis as a vascular graft. An alternative process employs elastically and plastically deformable structural strands, selectively plastically deformed by cold-working as they are moved toward a station for interbraiding with textile strands to form the prosthesis.
摘要翻译：公开了一种用于制造管腔内植入的假体的方法。假体由金属或聚合单丝的柔性管状插入结构和聚合复丝纱线形成，并且可以通过轴向伸长而弹性变形以减小其直径。单丝和复丝纱缠绕在轴向间隔开的螺旋上的心轴上，同心于假体的共同中心轴线。通过在缠绕在心轴上的时效硬化或其它热定型阶段，或者通过可控制地塑性地使股线变形的冷加工阶段，单丝在与复丝纱线相互交织之前被选择性地成形。成形的结构丝线协作以赋予假体其标称形状和弹性。纺织股线与结构股线接合以提供占据相邻结构股线之间间隙的片材，以减少渗透性，从而增强假体作为血管移植物的效用。一种替代方法采用弹性和塑性变形的结构股，当它们朝向工位移动以与织物股线相互作用以形成假体时，通过冷加工选择性塑性变形。

29. 发明授权

US09278019B2 Anchors and methods for intestinal bypass sleeves 有权
标题翻译：肠旁路套管和方法
公开(公告)号：US09278019B2
公开(公告)日：2016-03-08
申请号：US13360689
申请日：2012-01-28
申请人： Paul J. Thompson , Kedar R. Belhe , Alexander D. Grafov
发明人： Paul J. Thompson , Kedar R. Belhe , Alexander D. Grafov
IPC分类号： A61M5/00 , A61F5/00 , A61F2/04 , A61F2/24
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/24 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2220/0008
摘要： A gastrointestinal device for implanting within a pylorus, a duodenal bulb, and a duodenum of a patient's gastrointestinal tract includes an expandable structure including a proximal portion having a plurality of spring arms and a distal portion having a plurality of spring arms, the proximal and distal portions coupled by a rigid central cylinder having a diameter capable of fitting within the pylorus and having a length greater than a width of the pylorus. An intestinal bypass sleeve is coupled to at least one of the proximal and distal portions of the expandable structure and having a length sufficient to extend at least partially into the duodenum. In the expanded configuration, the proximal portion has a diameter larger than a maximum opening diameter of the pylorus and further wherein, in the expanded configuration, the distal portion has a diameter larger than a maximum opening diameter of the pylorus.
摘要翻译：用于植入在幽门，十二指肠球和患者胃肠道十二指肠内的胃肠装置包括可扩张结构，其包括具有多个弹簧臂的近端部分和具有多个弹簧臂的远侧部分，近端和远端部分通过刚性中心圆柱体联接，所述刚性中心圆柱体具有能够配置在幽门内并且具有大于幽门宽度的长度的直径。肠旁路套管联接到可扩张结构的近端部分和远端部分中的至少一个，并且具有足以至少部分延伸到十二指肠的长度。在扩张构造中，近侧部分具有大于幽门的最大开口直径的直径，此外，在扩张构造中，远侧部分的直径大于幽门的最大开口直径。

30. 发明授权

US08721356B2 Dock with compliant connector mount 有权
标题翻译：底座带有兼容的连接器支架
公开(公告)号：US08721356B2
公开(公告)日：2014-05-13
申请号：US13610832
申请日：2012-09-11
申请人： Michael J. Webb , Ian P. Colahan , Paul J. Thompson
发明人： Michael J. Webb , Ian P. Colahan , Paul J. Thompson
IPC分类号： H01R13/64
CPC分类号： G06F1/1683 , F16C11/12 , G06F1/1632 , H01R13/58 , H01R13/6315 , H01R33/975 , H04M1/0274 , H04M1/04
摘要： Docking stations having a connector with a compliant mount to provide improved durability and flexibility are provided herein. The compliant mount may couple a connector to a base of a docking station and may include at least a first and second flexure disposed therebetween. The first and second flexure may be configured to have flexural movement in along transverse direction so that, in combination, the flexural movement pivots the connector about a virtual pivot point a distance away from the flexures. The first and second flexures may be configured to project the virtual pivot point to a location on the connector where the connector protrudes from an opening in a docking housing, thereby minimizing the clearance required between the connector and docking housing, while providing controlled movement of the connector relative the dock.
摘要翻译：具有带柔性安装座的连接器以提供改进的耐久性和柔性的对接站在这里提供。柔性安装件可以将连接器连接到对接站的底座，并且可以包括至少设置在其间的第一和第二挠曲件。第一和第二挠曲可以被配置为沿着横向方向具有弯曲运动，使得组合地，弯曲运动使连接器围绕虚拟枢轴点远离弯曲部一点距离。第一和第二挠曲可以被配置为将虚拟枢轴点投影到连接器上的位置，其中连接器从对接壳体中的开口突出，从而最小化连接器和对接壳体之间所需的间隙，同时提供控制的移动连接器相对于坞站。

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