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    • 1. 发明授权
    • Medical device having a constricted region for occluding fluid flow in a
body lumen
    • 具有用于阻塞体腔内的流体流动的收缩区域的医疗装置
    • US5919224A
    • 1999-07-06
    • US797983
    • 1997-02-12
    • Paul J. ThompsonClaude Clerc
    • Paul J. ThompsonClaude Clerc
    • A61B17/00A61B17/12A61F2/82A61F2/06A61M29/00
    • A61B17/12109A61B17/12022A61B17/12172
    • The present invention is an occlusion device adapted for implantation into a fluid flow-supporting body lumen. The occlusion device comprises a flexible support structure and a flexible fluid flow-occluding membrane that is positioned concentric with the flexible support structure. The support structure is formed from a plurality of interwoven filaments that form an axially flexible and radially compressible structure that, in its expanded state, engages the lumen. The membrane generally includes a constricted region and constriction means, such as a mechanical seal, for closing the membrane at one end. The membrane is formed from a plurality of filaments, and in one embodiment, the membrane filaments are tightly interbraided with the structure filaments to form the occlusion device. Alternatively, the membrane is separately fabricated of interwoven filaments, and is positioned either within the support structure or without the structure so as to surround the support structure.
    • 本发明是一种适于植入流体流动支撑体腔内的闭塞装置。 闭塞装置包括柔性支撑结构和与柔性支撑结构同心定位的柔性流体阻流膜。 支撑结构由多个交织的长丝形成,其形成轴向柔性且可径向压缩的结构,其在其膨胀状态下与内腔接合。 膜通常包括用于在一端封闭膜的收缩区域和收缩装置,例如机械密封。 膜由许多细丝形成,在一个实施方案中,膜丝与结构细丝紧密接触以形成遮挡装置。 或者,膜分开地由交织的长丝制成,并且被定位在支撑结构内或不包括结构以包围支撑结构。
    • 2. 发明授权
    • Occlusion device
    • 闭塞装置
    • US06193748B1
    • 2001-02-27
    • US09332284
    • 1999-06-11
    • Paul J. ThompsonClaude Clerc
    • Paul J. ThompsonClaude Clerc
    • A61F200
    • A61B17/12109A61B17/12022A61B17/12172
    • The present invention is an occlusion device adapted for implantation into a fluid flow-supporting body lumen. The occlusion device comprises a flexible support structure and a flexible fluid flow-occluding membrane that is positioned concentric with the flexible support structure. The support structure is formed from a plurality of interwoven filaments that form an axially flexible and radially compressible structure that, in its expanded state, engages the lumen. The membrane generally includes a constricted region and constriction means, such as a mechanical seal, for closing the membrane at one end. The membrane is formed from a plurality of filaments, and in one embodiment, the membrane filaments are tightly interbraided with the structure filaments to form the occlusion device. Alternatively, the membrane is separately fabricated of interwoven filaments, and is positioned either within the support structure or without the structure so as to surround the support structure.
    • 本发明是一种适于植入流体流动支撑体腔内的闭塞装置。 闭塞装置包括柔性支撑结构和与柔性支撑结构同心定位的柔性流体阻流膜。 支撑结构由多个交织的长丝形成,其形成轴向柔性且可径向压缩的结构,其在其膨胀状态下与内腔接合。 膜通常包括用于在一端封闭膜的收缩区域和收缩装置,例如机械密封。 膜由许多细丝形成,在一个实施方案中,膜丝与结构细丝紧密接触以形成遮挡装置。 或者,膜分开地由交织的长丝制成,并且被定位在支撑结构内或不包括结构以包围支撑结构。
    • 7. 发明授权
    • External anchoring configurations for modular gastrointestinal prostheses
    • 模块化胃肠假体的外部锚定配置
    • US08282598B2
    • 2012-10-09
    • US12833605
    • 2010-07-09
    • Kedar R. BelhePaul J. Thompson
    • Kedar R. BelhePaul J. Thompson
    • A61M39/00
    • A61F5/0076A61F5/003
    • Components may be used separately or in combination to create anchoring systems for intra-luminal implants for the treatment of metabolic disorders such as obesity and diabetes. Various systems include an external component adapted for deployment around a portion of the gastrointestinal tract (e.g., the duodenum) and an internal component adapted for implantation within the gastrointestinal tract. Various systems use anchors that are based on mechanical interference, elasticity, spring force, shape memory transformation, magnetic attraction, repulsion and/or levitation. Various embodiments rely on longitudinal anchoring of the implants with minimal force against tissue.
    • 组分可以单独使用或组合使用以产生腔内植入物用于治疗代谢紊乱如肥胖症和糖尿病的锚定系统。 各种系统包括适于部署在胃肠道的一部分(例如,十二指肠)周围的外部部件和适于植入胃肠道内部的内部部件。 各种系统使用基于机械干涉,弹性,弹簧力,形状记忆变换,磁吸引,排斥和/或悬浮的锚。 各种实施例依赖于对组织的最小力的植入物的纵向锚固。
    • 8. 发明授权
    • Stent with dual support structure
    • 支架双支撑结构
    • US08007527B2
    • 2011-08-30
    • US12633246
    • 2009-12-08
    • Paul J. Thompson
    • Paul J. Thompson
    • A61F2/06
    • A61F2/86A61F2/91A61F2/915A61F2002/91508A61F2002/91525A61F2002/91541A61F2002/91558A61F2002/91566A61F2230/0013A61F2230/0054A61F2250/001
    • A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
    • 管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。 管包括在第一和第二端之间延伸的结构梁。 当管从未展开的直径变大到扩大的直径时,结构梁从第一几何变化到第二几何形状。 结构梁包括第一和第二纵向元件,每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。 当管从未展开的直径改变到扩大的直径时,所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状,以使间隔保持基本上不变,因为管从未展开的直径变大到扩大的直径 直径。
    • 10. 发明授权
    • Grip for stent delivery system
    • 夹持支架输送系统
    • US06749627B2
    • 2004-06-15
    • US09765721
    • 2001-01-18
    • Paul J. ThompsonThomas M. Benson
    • Paul J. ThompsonThomas M. Benson
    • A61F206
    • A61F2/95A61B17/2909A61F2002/9517A61M2025/09116A61M2025/09125
    • A stent delivery system includes inner and outer tubular members with the outer tubular member sized to pass through the body lumen to the deployment site and with the inner tubular member sized to be received within the outer tubular member. The inner and outer tubular members are axially slideable relative to one another between a transport position and a deploy position. The inner tubular member has a stent attachment location at its distal end. The stent attachment location is covered by the outer tubular member when the inner and outer tubular members are in the transport position. The stent attachment location is exposed when the inner and outer tubular members are in the deploy position. A first handle is provided rotatably connected to a proximal end of the outer tubular member for the first handle to transmit to the outer tubular member axial forces applied to the handle by an operator and to rotate freely about the axis relative to the outer tubular member.
    • 支架输送系统包括内部和外部管状构件,外部管状构件的尺寸设计成穿过体腔到达展开位置,并且内部管状构件的尺寸设置成容纳在外部管状构件内。 内部和外部管状构件在运输位置和展开位置之间可相对于彼此轴向滑动。 内部管状构件在其远端具有支架附接位置。 当内部和外部管状构件处于运输位置时,支架附接位置被外部管状构件覆盖。 当内部和外部管状构件处于展开位置时,支架附接位置被暴露。 第一手柄设置成可旋转地连接到外部管状构件的近端,用于第一手柄,以便通过操作者向外部管状构件传递施加到手柄的轴向力,并相对于外部管状构件绕该轴线自由旋转。