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21. 发明申请

US20060293738A1 Systems and methods for creating a lesion using transjugular approach 失效
公开(公告)号：US20060293738A1
公开(公告)日：2006-12-28
申请号：US11168234
申请日：2005-06-27
申请人： Jeffrey Cross , Paul DiCarlo
发明人： Jeffrey Cross , Paul DiCarlo
IPC分类号： A61N1/00
CPC分类号： A61B18/00 , A61B18/1477 , A61B18/1492 , A61B2018/0016 , A61B2018/00345 , A61B2018/00404 , A61B2018/00577 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A method of treating a tissue region includes inserting a flexible sheath within a vessel, the vessel leading to a tissue region, placing a distal end of the sheath through a wall of the vessel to thereby position the distal end is at or adjacent the tissue region, deploying a plurality of electrodes from the distal end of the sheath such that tips of the deployed electrodes approximately face towards a proximal end, and delivering energy to the tissue region using the deployed electrodes.

22. 发明申请

US20060184139A1 Pressure activated safety valve with improved flow characteristics and durability 有权
标题翻译：压力启动安全阀具有改善的流动特性和耐久性
公开(公告)号：US20060184139A1
公开(公告)日：2006-08-17
申请号：US11057286
申请日：2005-02-11
申请人： Karla Quigley , Paul DiCarlo , Mark Wolfson
发明人： Karla Quigley , Paul DiCarlo , Mark Wolfson
IPC分类号： A61M5/00
CPC分类号： A61M39/26 , A61M1/3661 , A61M1/367 , A61M39/0613
摘要： A valve assembly for vascular access, comprising a body defining a lumen adapted for flowing blood, the body including a luer housing for connection with a first blood conduit and a barb housing for connection with a second blood conduit and a plurality of slitted membranes disposed within the body portion, each of the slitted membranes generating a partial pressure drop for flow therethrough, each of the partial pressure drops being smaller than a total pressure drop for flow through the body portion.
摘要翻译：一种用于血管通路的阀组件，包括限定适于流动血液的内腔的主体，所述主体包括用于与第一血液管道连接的鲁尔壳体和用于与第二血液导管连接的倒钩壳体和设置在其中的多个切割膜主体部分中，每个分切膜产生用于流过其的分压压力，每个分压力小于通过主体部分流动的总压降。

23. 发明申请

US20060089635A1 Methods and apparatus for focused bipolar tissue ablation using an insulated shaft 审中-公开
标题翻译：使用绝缘轴的聚焦双极组织消融的方法和装置
公开(公告)号：US20060089635A1
公开(公告)日：2006-04-27
申请号：US10971373
申请日：2004-10-22
申请人： Kimbolt Young , Steve Anderson , Paul DiCarlo , Jeffrey Zerfas
发明人： Kimbolt Young , Steve Anderson , Paul DiCarlo , Jeffrey Zerfas
IPC分类号： A61B18/14
CPC分类号： A61B18/082 , A61B18/1477 , A61B18/148 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1475
摘要： A tissue ablation probe is provided. The probe comprises a proximal electrode element, which includes a proximal electrode stem and a deployable proximal electrode array, and a distal electrode element, which includes a distal electrode stem and a deployable distal electrode array. The probe is configured, such that a majority of electrical energy conveyed between the proximal and distal electrode elements is conveyed between distal termini of the electrode arrays, whereas a relatively small amount of the electrical energy is conveyed between the electrode stems. One or more of the electrodes on the arrays may be optionally insulated to further enhance the electrical characteristics of the arrays.
摘要翻译：提供组织消融探针。探针包括近端电极元件，其包括近端电极杆和可展开的近端电极阵列，以及远端电极元件，其包括远端电极杆和可展开的远端电极阵列。探针被构造成使得在近端和远端电极元件之间传送的大部分电能在电极阵列的远端之间传送，而相对少量的电能在电极杆之间传送。阵列上的一个或多个电极可以可选地绝缘，以进一步增强阵列的电特性。

24. 发明申请

US20050238870A1 Embolization 审中-公开
标题翻译：栓塞
公开(公告)号：US20050238870A1
公开(公告)日：2005-10-27
申请号：US10830195
申请日：2004-04-22
申请人： Marcia Buiser , Paul DiCarlo , Thomas Casey , Erin McKenna , Robert Rioux
发明人： Marcia Buiser , Paul DiCarlo , Thomas Casey , Erin McKenna , Robert Rioux
IPC分类号： A61K47/48 , C08J9/00 , B32B5/16
CPC分类号： A61K47/557 , Y10T428/25
摘要： Embolization, as well as related compositions and methods, are disclosed.
摘要翻译：栓塞以及相关组合物和方法被公开。

25. 发明申请

US20050203505A1 Ablation probe with peltier effect thermal control 有权
标题翻译：消融探头与珀耳帖效应热控制
公开(公告)号：US20050203505A1
公开(公告)日：2005-09-15
申请号：US10802092
申请日：2004-03-15
申请人： Joseph Megerman , Paul DiCarlo
发明人： Joseph Megerman , Paul DiCarlo
IPC分类号： A61B18/02 , A61B18/08 , A61B18/14
CPC分类号： A61B18/02 , A61B18/1477 , A61B2018/0237 , A61B2018/0243 , A61B2018/087 , A61B2018/143 , A61B2018/1432
摘要： A tissue ablation probe, system, and method are provided. The ablation probe comprises an elongated member, an ablative element mounted on the distal end of the elongated member, and at least one thermoelectric device mounted to the member in thermal communication with the ablative element. The system may include the ablation probe, thermal control circuitry for controlling the thermal effect of the thermoelectric device, and an ablation source for suppying ablation energy to the ablative element. A plurality of circumferentially distributed thermoelectric devices can be provided, so that radial tissue sectors can be selectively affected by independently controlling the thermal effect of the thermoelectric devices. In one embodiment, the thermoelectric device(s) can be used to cool a heat ablative element. In another embodiment, the thermoelectric device(s) can be used to heat an ablative element, thereby forming a heat ablative element. In still another embodiment, the thermoelectric device(s) can be used to cryogenically cool an ablative element, thereby forming a cryogenic ablative element.
摘要翻译：提供组织消融探针，系统和方法。消融探针包括细长构件，安装在细长构件的远端上的消融元件以及安装到与烧蚀元件热连通的构件的至少一个热电装置。该系统可以包括消融探针，用于控制热电装置的热效应的热控制电路，以及用于将烧蚀能量用于烧蚀元件的消融源。可以提供多个周向分布的热电装置，使得可以通过独立地控制热电装置的热效应来选择性地影响径向组织扇区。在一个实施例中，热电装置可以用于冷却热消融元件。在另一个实施例中，热电装置可以用于加热烧蚀元件，从而形成热消融元件。在另一个实施例中，热电装置可用于低温冷却烧蚀元件，从而形成低温烧蚀元件。

26. 发明申请

US20050171525A1 System and method for performing ablation using a balloon 有权
标题翻译：使用气球进行消融的系统和方法
公开(公告)号：US20050171525A1
公开(公告)日：2005-08-04
申请号：US10768037
申请日：2004-02-02
申请人： Robert Rioux , Paul DiCarlo
发明人： Robert Rioux , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/14 , A61B18/1482 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00238 , A61B2018/00255 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00702 , A61B2018/00875
摘要： An apparatus comprises a catheter, a conductive element and a balloon. The catheter has a lumen. The conductive element is disposed along the catheter. The balloon has an interior in fluid communication with the lumen of the catheter. The balloon is formed of a conductive material conductively coupled to the conductive element. The balloon has a collapsed configuration and an expanded configuration.
摘要翻译：一种装置包括导管，导电元件和气球。导管有一个内腔。导电元件沿导管设置。气囊具有与导管的内腔流体连通的内部。气球由导电性地耦合到导电元件的导电材料形成。气球具有收缩配置和扩展配置。

27. 发明申请

US20050020965A1 Devices and methods for delivering agents to tissue region while preventing leakage 审中-公开
标题翻译：用于将药剂递送到组织区域同时防止泄漏的装置和方法
公开(公告)号：US20050020965A1
公开(公告)日：2005-01-27
申请号：US10926853
申请日：2004-08-25
申请人： Robert Rioux , Steve Anderson , Paul DiCarlo
发明人： Robert Rioux , Steve Anderson , Paul DiCarlo
IPC分类号： A61M25/00 , A61N1/30
CPC分类号： A61M25/007 , A61B18/1477 , A61B2018/0063 , A61M25/003 , A61M25/0084 , A61M2025/0004 , A61M2025/0039 , A61M2025/0089
摘要： An apparatus for delivering a therapeutic or diagnostic agent to a target site within a body includes an outer tubular body, an inner tubular body slidably disposed within the outer tubular body, a substance delivery port located on the inner tubular body, and an electrode secured to the outer tubular body. The delivery port can be used to deliver a medical substance to the target site, and the electrode can be used to seal an access channel leading to the treatment site, thereby substantially preventing migration of material from the delivery site. In order to minimize the profile of the apparatus, a braided conductor can extend through the wall of the outer tubular body, thereby providing a means for delivering electrical energy to the electrode, while strengthening the wall of the outer tubular body to minimize the risk of rupture during delivery of the substance.
摘要翻译：用于将治疗剂或诊断剂递送到体内的靶部位的装置包括外管状体，可滑动地设置在外管状体内的内管体，位于内管体上的物质输送口，以及固定到外管体。输送口可以用于将药物输送到目标部位，并且电极可用于密封通向治疗部位的通道，从而基本上防止材料从输送部位迁移。为了最小化装置的轮廓，编织导体可以延伸穿过外部管状体的壁，从而提供用于将电能传递到电极的装置，同时加强外部管状体的壁以最小化在物质运送过程中破裂。

28. 发明授权

US06264689B1 Low profile medical stent 失效
标题翻译：低调医用支架
公开(公告)号：US06264689B1
公开(公告)日：2001-07-24
申请号：US09052214
申请日：1998-03-31
申请人： Darragh Colgan , Peter Hamilton , Paul DiCarlo
发明人： Darragh Colgan , Peter Hamilton , Paul DiCarlo
IPC分类号： A61F200
CPC分类号： A61F2/90 , A61F2/07 , A61F2/95 , A61F2002/9665 , A61F2210/0076 , A61F2230/0054 , A61F2250/0098
摘要： The invention relates to an implantable medical stent having a low profile for delivery through smaller lumens. The stent is constrained during delivery where the helically wrapped points of a diamond cell structure also include at least one crossed joint of intersecting strands to provide a reduced diameter.
摘要翻译：本发明涉及一种具有较低外形的可植入医用支架，用于通过更小的内腔输送。支架在输送期间被约束，其中金刚石单元结构的螺旋缠绕点还包括交叉股线的至少一个交叉接头以提供减小的直径。

29. 发明授权

US5258016A Suture anchor and driver assembly 失效
标题翻译：缝合锚和驱动装置
公开(公告)号：US5258016A
公开(公告)日：1993-11-02
申请号：US836679
申请日：1992-02-14
申请人： Gene P. DiPoto , Jeffrey C. Cerier , Russell F. Warren , Gerard S. Carlozzi , Paul DiCarlo , James W. Dwyer , Alan A. Small
发明人： Gene P. DiPoto , Jeffrey C. Cerier , Russell F. Warren , Gerard S. Carlozzi , Paul DiCarlo , James W. Dwyer , Alan A. Small
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B19/00 , A61B17/60
CPC分类号： A61F2/0811 , A61B17/0401 , A61B90/06 , A61B2017/00004 , A61B2017/0409 , A61B2017/0414 , A61B2017/0458 , A61B2017/0496 , A61B2017/06142 , A61B2090/062 , A61F2002/0888 , Y10S606/908 , Y10S606/91 , Y10S606/916
摘要： A suture anchor and anchor driver device for securely and accurately positioning and installing the suture anchor in place. The anchor has a rounded or pointed head and one or more ridges around it to help force fit the anchor into a hole and to hold it in place. A suture is positioned through the anchor for subsequent use during the surgical procedure. The driver device has a handle and an elongated shaft and is used to position and install the anchor in place. The anchor preferably snap fits onto the end of the shaft. A depth guide can be integrally or removably positioned on the shaft to ensure correct depth of placement. Alternately, the driver shaft is hollow and the anchor is positioned inside it and is implanted with a pusher member. The ends of the suture are affixed to the driver handle. Grooves can be provided on the driver and the anchor to prevent the suture from interfering with the positioning and installation procedure.
摘要翻译：一种缝合锚和锚固器驱动装置，用于将缝线锚定位和安装到位。锚具有圆形或尖头和围绕其的一个或多个脊，以帮助将锚固件压入孔并将其保持在适当位置。缝合线定位穿过锚固件，以便在手术过程中随后使用。驱动装置具有手柄和细长轴，并用于将锚定位和安装到位。锚固件优选卡扣配合到轴的端部上。深度引导件可以一体地或可拆卸地定位在轴上以确保正确的放置深度。或者，驱动器轴是中空的，并且锚定件位于其内部并且被植入推动器构件。缝合线的末端固定在驾驶员手柄上。可以在驾驶员和锚上提供槽，以防止缝合线干扰定位和安装过程。

30. 发明授权

US5224946A Bone anchor and method of anchoring a suture to a bone 失效
标题翻译：骨锚固和锚固方法
公开(公告)号：US5224946A
公开(公告)日：1993-07-06
申请号：US681070
申请日：1991-04-05
申请人： John O. Hayhurst , Alan A. Small , Jeffrey C. Cerier , Paul DiCarlo , James W. Dwyer
发明人： John O. Hayhurst , Alan A. Small , Jeffrey C. Cerier , Paul DiCarlo , James W. Dwyer
IPC分类号： A61B17/04 , A61B17/06 , A61B17/56 , A61B19/00 , A61F2/08
CPC分类号： A61F2/0811 , A61B17/0401 , A61B2017/0409 , A61B2017/0414 , A61B2017/0458 , A61B2017/0496 , A61B2017/06142 , A61B2090/062 , A61F2002/0888
摘要： A bone anchor (10) for securing a suture to a bone (38). The bone anchor (10) has a tip (16) at its distal end (18) and at least one resilient wall (27) extending to a trailing end (20) of the body (12) of the anchor. The wall (27) has a ridge (14), or barb, formed on an outer surface. The ridge (14) defines an edge (34) that digs into a hole (36) in the bone (38) in which it is positioned. A strand of suturing thread (22) extends through a suture receiving opening (24) in the tip (16) of the anchor. The method of the present invention employs the suture anchor (10) and includes the steps of forming a hole (36) in a bone (38) and inserting the suture anchor (10) to a desired depth in the hole (36) in the bone (38) using an inserter device (100). Suturing thread ( 22) extends from the suture receiving opening (24) in the tip and along the length of the walls (27,28) out of the hole (36) in the bone (38). An anchor spreader (130) is used to firmly seat the anchor (10) in the hole (36). The suture (22) is pulled at the same time to help seat the barbs 14 on the anchor (10) into the bone (38).

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