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1. 发明申请

US20060089635A1 Methods and apparatus for focused bipolar tissue ablation using an insulated shaft 审中-公开
标题翻译：使用绝缘轴的聚焦双极组织消融的方法和装置
公开(公告)号：US20060089635A1
公开(公告)日：2006-04-27
申请号：US10971373
申请日：2004-10-22
申请人： Kimbolt Young , Steve Anderson , Paul DiCarlo , Jeffrey Zerfas
发明人： Kimbolt Young , Steve Anderson , Paul DiCarlo , Jeffrey Zerfas
IPC分类号： A61B18/14
CPC分类号： A61B18/082 , A61B18/1477 , A61B18/148 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1475
摘要： A tissue ablation probe is provided. The probe comprises a proximal electrode element, which includes a proximal electrode stem and a deployable proximal electrode array, and a distal electrode element, which includes a distal electrode stem and a deployable distal electrode array. The probe is configured, such that a majority of electrical energy conveyed between the proximal and distal electrode elements is conveyed between distal termini of the electrode arrays, whereas a relatively small amount of the electrical energy is conveyed between the electrode stems. One or more of the electrodes on the arrays may be optionally insulated to further enhance the electrical characteristics of the arrays.
摘要翻译：提供组织消融探针。探针包括近端电极元件，其包括近端电极杆和可展开的近端电极阵列，以及远端电极元件，其包括远端电极杆和可展开的远端电极阵列。探针被构造成使得在近端和远端电极元件之间传送的大部分电能在电极阵列的远端之间传送，而相对少量的电能在电极杆之间传送。阵列上的一个或多个电极可以可选地绝缘，以进一步增强阵列的电特性。

2. 发明申请

US20070161980A1 RF ablation probes with tine valves 有权
标题翻译：射频消融探头与齿阀
公开(公告)号：US20070161980A1
公开(公告)日：2007-07-12
申请号：US11323941
申请日：2005-12-29
申请人： Kimbolt Young , Gerald Hubbs , Steve Pickett , Gene McCallister , John Hewitt , Jeffrey Zerfas
发明人： Kimbolt Young , Gerald Hubbs , Steve Pickett , Gene McCallister , John Hewitt , Jeffrey Zerfas
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/148 , A61B2018/1467 , A61B2018/1475 , A61B2218/002
摘要： A tissue ablation probe is provided. The tissue ablation probe comprises an elongated shaft, at least one electrode tine carried by the elongated shaft, at least one tine exit from which the electrode tine(s) can be deployed from the elongated shaft and retracted within the elongated shaft, and a sheath covering the electrode tine exit(s). The sheath may, e.g., line an exterior surface of the elongated shaft or an interior surface of the elongated shaft. The sheath has at least one tine valve (e.g., a slit) positioned over the electrode tine exit(s) and configured to open when the electrode tine is deployed and to close when the electrode tine(s) is retracted. In one embodiment, the tine valve(s) is configured to open in response to pressure exerted during deployment of the electrode tine(s). In another embodiment, the tine valve(s) is configured to hinder the entry of biological material within the elongated shaft. In one embodiment, the sheath is pliable, such that the tine valve(s) can more easily hinder the entry of the biological material.
摘要翻译：提供组织消融探针。所述组织消融探针包括细长轴，由所述细长轴承载的至少一个电极齿条，至少一个齿出口，所述电极齿可以从所述至少一个齿出口从所述细长轴展开并缩回到所述细长轴内，覆盖电极齿出口。护套可以例如对细长轴的外表面或细长轴的内表面进行排列。护套具有定位在电极齿出口上方的至少一个齿阀（例如狭缝），并且构造成当电极齿展开时打开，并且当电极齿被缩回时闭合。在一个实施例中，齿阀构造成响应于在电极尖的展开期间施加的压力而打开。在另一个实施例中，齿形阀构造成阻止生物材料进入细长轴内。在一个实施例中，鞘是柔韧的，使得齿可以更容易地阻碍生物材料的进入。

3. 发明申请

US20060095029A1 Ablation probe with flared electrodes 有权
公开(公告)号：US20060095029A1
公开(公告)日：2006-05-04
申请号：US10977274
申请日：2004-10-28
申请人： Kimbolt Young , Jeffrey Zerfas
发明人： Kimbolt Young , Jeffrey Zerfas
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B18/1477 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1475
摘要： An ablation device includes a cannula having a proximal end, a distal end, and a lumen extending between the proximal and the distal ends, and a first array of electrodes at least partially disposed within the lumen, the first array of electrodes slidable relative to the cannula, each of the electrodes having a first configuration when inside the lumen, and a second configuration when unconfined outside the lumen, wherein one of the electrodes has a flared deployed profile.

4. 发明申请

US20090131855A1 APPARATUS AND METHODS FOR DRUG RELEASE IN TISSUE ABLATION PROCEDURES 有权
标题翻译：组织吸收程序中药物释放的装置和方法
公开(公告)号：US20090131855A1
公开(公告)日：2009-05-21
申请号：US12271714
申请日：2008-11-14
申请人： Kimbolt Young , Steven Walak , Paul DiCarlo
发明人： Kimbolt Young , Steven Walak , Paul DiCarlo
IPC分类号： A61M37/00 , A61B18/18
CPC分类号： A61B18/1477 , A61B18/148 , A61B2018/00154 , A61B2018/143 , A61B2018/1432 , A61B2018/1475 , A61B2018/1495 , A61B2218/002
摘要： Tissue ablation probes and methods for treating tissue are provided. The tissue ablation probe comprises an elongated probe shaft, at least one electrode carried by the distal end of the probe shaft, and a pharmaceutical agent carried by the probe shaft. The pharmaceutical agent may be disposed on the electrode(s), the probe shaft, or a releasable portion associated with the electrode or the probe shaft. A method for treating tissue comprises introducing a tissue ablation probe to a tissue site, operating the tissue ablation probe to ablate tissue at the tissue site, and releasing a pharmaceutical agent from the tissue ablation probe at the tissue site.
摘要翻译：提供组织消融探针和治疗组织的方法。组织消融探针包括细长的探针轴，由探针轴的远端承载的至少一个电极和由探针轴承载的药剂。药剂可以设置在与电极或探针轴相关联的电极，探针轴或可释放部分上。一种用于治疗组织的方法包括将组织消融探针引入组织部位，操作组织消融探针以烧蚀组织部位处的组织，以及在组织部位从组织消融探针释放药剂。

5. 发明申请

US20070088347A1 Magnetically augmented radio frequency ablation 有权
标题翻译：磁放大射频消融
公开(公告)号：US20070088347A1
公开(公告)日：2007-04-19
申请号：US11250063
申请日：2005-10-13
申请人： Kimbolt Young , Steven M. Anderson , John Spiridigliozzi , Paul DiCarlo
发明人： Kimbolt Young , Steven M. Anderson , John Spiridigliozzi , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1477
摘要： A tissue ablation assembly comprises an elongate probe device, at least one ablation electrode element carried by the probe device for conveying ablation energy, and at least one magnetic element for substantially altering the path of the ablation energy conveyed by the electrode element(s). In one embodiment, the magnetic element substantially urges the ablation energy radially outward. In another embodiment, magnetic element takes the form of a ring magnet that exhibits at least four alternating magnetic poles circumferentially disposed around the probe device axis. A method of treating tissue (e.g., a tumor) is also provided. The method comprises introducing a probe device into the patient, conveying ablation energy from the probe device, and applying a magnetic field adjacent the probe device to substantially alter the path of the ablation energy, e.g., by urging the ablation energy conveyed from the probe device radially outward into the tissue to create a tissue lesion, or by urging the ablation energy longitudinally.
摘要翻译：组织消融组件包括细长的探针装置，由探针装置承载的用于传送消融能量的至少一个消融电极元件以及用于基本上改变由电极元件传送的消融能量的路径的至少一个磁性元件。在一个实施例中，磁性元件基本上推动消融能量径向向外。在另一个实施例中，磁性元件呈环形磁铁的形式，其呈现围绕探针器件轴线周向设置的至少四个交变磁极。还提供了治疗组织（例如肿瘤）的方法。该方法包括将探针装置引入患者体内，从探针装置输送消融能量，以及施加邻近探针装置的磁场，以基本上改变消融能量的路径，例如通过促使从探针装置传送的消融能量径向向外进入组织以产生组织损伤，或通过纵向推动消融能量。

6. 发明授权

US07962223B2 Ablation probe for drug release in tissue ablation procedures 有权
标题翻译：组织消融术中药物释放消融探针
公开(公告)号：US07962223B2
公开(公告)日：2011-06-14
申请号：US12271714
申请日：2008-11-14
申请人： Kimbolt Young , Steven Walak , Paul DiCarlo
发明人： Kimbolt Young , Steven Walak , Paul DiCarlo
IPC分类号： A61N1/06
CPC分类号： A61B18/1477 , A61B18/148 , A61B2018/00154 , A61B2018/143 , A61B2018/1432 , A61B2018/1475 , A61B2018/1495 , A61B2218/002
摘要： Tissue ablation probes and methods for treating tissue are provided. The tissue ablation probe comprises an elongated probe shaft, at least one electrode carried by the distal end of the probe shaft, and a pharmaceutical agent carried by the probe shaft. The pharmaceutical agent may be disposed on the electrode(s), the probe shaft, or a releasable portion associated with the electrode or the probe shaft. A method for treating tissue comprises introducing a tissue ablation probe to a tissue site, operating the tissue ablation probe to ablate tissue at the tissue site, and releasing a pharmaceutical agent from the tissue ablation probe at the tissue site.
摘要翻译：提供组织消融探针和治疗组织的方法。组织消融探针包括细长的探针轴，由探针轴的远端承载的至少一个电极和由探针轴承载的药剂。药剂可以设置在与电极或探针轴相关联的电极，探针轴或可释放部分上。一种用于治疗组织的方法包括将组织消融探针引入组织部位，操作组织消融探针以烧蚀组织部位处的组织，以及在组织部位从组织消融探针释放药剂。

7. 发明授权

US07744596B2 Magnetically augmented radio frequency ablation 有权
标题翻译：磁放大射频消融
公开(公告)号：US07744596B2
公开(公告)日：2010-06-29
申请号：US11250063
申请日：2005-10-13
申请人： Kimbolt Young , Steven M. Anderson , John Spiridigliozzi , Paul DiCarlo
发明人： Kimbolt Young , Steven M. Anderson , John Spiridigliozzi , Paul DiCarlo
IPC分类号： A61B18/18
CPC分类号： A61B18/1477
摘要： A tissue ablation assembly comprises an elongate probe device, at least one ablation electrode element carried by the probe device for conveying ablation energy, and at least one magnetic element for substantially altering the path of the ablation energy conveyed by the electrode element(s). In one embodiment, the magnetic element substantially urges the ablation energy radially outward. In another embodiment, magnetic element takes the form of a ring magnet that exhibits at least four alternating magnetic poles circumferentially disposed around the probe device axis. A method of treating tissue (e.g., a tumor) is also provided. The method comprises introducing a probe device into the patient, conveying ablation energy from the probe device, and applying a magnetic field adjacent the probe device to substantially alter the path of the ablation energy, e.g., by urging the ablation energy conveyed from the probe device radially outward into the tissue to create a tissue lesion, or by urging the ablation energy longitudinally.
摘要翻译：组织消融组件包括细长探针装置，由探针装置承载的至少一个消融电极元件，用于传送消融能量，以及至少一个磁性元件，用于基本上改变由电极元件传送的消融能量的路径。在一个实施例中，磁性元件基本上推动消融能量径向向外。在另一个实施例中，磁性元件呈环形磁铁的形式，其呈现围绕探针器件轴线周向设置的至少四个交变磁极。还提供了治疗组织（例如肿瘤）的方法。该方法包括将探针装置引入患者体内，从探针装置输送消融能量，以及施加邻近探针装置的磁场，以基本上改变消融能量的路径，例如通过促使从探针装置传送的消融能量径向向外进入组织以产生组织损伤，或通过纵向推动消融能量。

8. 发明申请

US20100130974A1 ABLATION PROBE WITH HEAT SINK 有权
标题翻译：热吸收探测器
公开(公告)号：US20100130974A1
公开(公告)日：2010-05-27
申请号：US12693330
申请日：2010-01-25
申请人： Kimbolt Young , Steve Anderson , John Spiridigliozzi
发明人： Kimbolt Young , Steve Anderson , John Spiridigliozzi
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00011 , A61B2018/143 , A61B2018/1475
摘要： An ablation device includes an electrode having an enclosed lumen, and a heat sink located within the lumen. An ablation device includes an elongated body, an electrode secured to the elongated body, and a heat sink connected to the electrode, wherein the heat sink is confined by the electrode and at least a portion of the elongated body. An ablation device includes an electrode, and a heat sink connected to the electrode, wherein the heat sink is not connected to a pump.
摘要翻译：消融装置包括具有封闭腔的电极和位于内腔内的散热器。消融装置包括细长体，固定到细长体的电极和连接到电极的散热器，其中散热器被电极和细长体的至少一部分限制。消融装置包括电极和连接到电极的散热器，其中散热器不连接到泵。

9. 发明授权

US08007497B2 Ablation probe with heat sink 有权
标题翻译：消融探头带散热片
公开(公告)号：US08007497B2
公开(公告)日：2011-08-30
申请号：US12693330
申请日：2010-01-25
申请人： Kimbolt Young , Steve Anderson , John Spiridigliozzi
发明人： Kimbolt Young , Steve Anderson , John Spiridigliozzi
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00011 , A61B2018/143 , A61B2018/1475
摘要： An ablation device includes an electrode having an enclosed lumen, and a heat sink located within the lumen. An ablation device includes an elongated body, an electrode secured to the elongated body, and a heat sink connected to the electrode, wherein the heat sink is confined by the electrode and at least a portion of the elongated body. An ablation device includes an electrode, and a heat sink connected to the electrode, wherein the heat sink is not connected to a pump.
摘要翻译：消融装置包括具有封闭腔的电极和位于内腔内的散热器。消融装置包括细长体，固定到细长体的电极和连接到电极的散热器，其中散热器被电极和细长体的至少一部分限制。消融装置包括电极和连接到电极的散热器，其中散热器不连接到泵。

10. 发明授权

US07959629B2 Multi-zone bipolar ablation probe assembly 失效
标题翻译：多区双极消融探头组件
公开(公告)号：US07959629B2
公开(公告)日：2011-06-14
申请号：US12173653
申请日：2008-07-15
申请人： Kimbolt Young , Steve Anderson
发明人： Kimbolt Young , Steve Anderson
IPC分类号： A61B18/14
CPC分类号： A61B18/1482 , A61B18/1477 , A61B18/1492 , A61B2018/00214 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1475
摘要： A medical probe assembly, tissue treatment system, and method are provided for ablating tissue. The probe assembly comprises an elongated member and electrode elements mechanically coupled to the distal end of the elongated member. The electrode elements are configurable as two bipolar electrode pairs with a common electrode element. At least one of the electrode elements comprises a plurality of electrodes (such as, e.g., needle electrodes) radially extendable from the elongated member. An ablation source, such as a radio frequency source, can be connected to the probe assembly in order to convey ablation energy to the electrode pairs, either simultaneously or sequentially.
摘要翻译：提供医疗探针组件，组织处理系统和方法来烧蚀组织。探针组件包括细长构件和机械地联接到细长构件的远端的电极元件。电极元件可配置为具有公共电极元件的两个双极电极对。至少一个电极元件包括从细长构件可径向延伸的多个电极（例如，例如针电极）。诸如射频源的消融源可以连接到探针组件，以将消融能量同时或顺序地传送到电极对。

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