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11. 发明授权

US08702578B2 Positioning device and method for positioning a load 有权
标题翻译：定位装置及定位方法
公开(公告)号：US08702578B2
公开(公告)日：2014-04-22
申请号：US12130826
申请日：2008-05-30
申请人： Wolfram Fahrig , Klaus Herrmann , Jochen Miguel Löseken
发明人： Wolfram Fahrig , Klaus Herrmann , Jochen Miguel Löseken
IPC分类号： A61G10/00 , A61G7/00 , G01B7/00
CPC分类号： A61B6/4092 , A61B6/0457 , A61B6/5276 , A61G13/02 , A61G13/04 , A61G13/06 , A61N5/1049 , A61N2005/1057 , B25J9/1638 , G05B2219/35285 , G05B2219/37285 , G05B2219/39176 , G05B2219/45117 , G05B2219/49189
摘要： A positioning device for positioning a load is provided. The positioning device includes a motor, a measuring device, and an evaluation device. The measuring device is associated with the motor, and is operable to ascertain measurement data that characterizes the motor current consumption by the motor in the positioning of the load. The evaluation device evaluates the measurement data that have been ascertained by the measuring device, so that in that way the loading of the positioning device by the load can be ascertained.
摘要翻译：提供了一种用于定位负载的定位装置。定位装置包括电动机，测量装置和评估装置。测量装置与电动机相关联，并且可操作地确定表征电动机在负载定位中的电动机电流消耗的测量数据。评估装置评估由测量装置确定的测量数据，从而可以确定负载时定位装置的负载。

12. 发明授权

US08462912B2 Computed tomography examination and particle therapy treatment 失效
标题翻译：计算机断层扫描检查和颗粒治疗
公开(公告)号：US08462912B2
公开(公告)日：2013-06-11
申请号：US12551024
申请日：2009-08-31
申请人： John P. O'Connor , Charles Shaughnessy
发明人： John P. O'Connor , Charles Shaughnessy
IPC分类号： A61N5/10 , G21K5/08
CPC分类号： A61B6/04 , A61B6/0478 , A61B6/12 , A61B6/4092 , A61B6/4429 , A61B6/547 , A61N5/1049 , A61N5/1078 , A61N2005/1061 , A61N2005/1063 , A61N2005/1087
摘要： An operation room may comprise both an object scanning apparatus for examining an object using x-ray radiation and an irradiation component for treating an object using particle radiation. A support article upon which the object may reside during (both) the examination and treatment may be configured to rotate about an axis substantially perpendicular to a plane through which x-ray radiation travels, may be configured to tilt with respect to the axis, and/or may be configured to yaw with respect to the axis. In this way, the relative orientation of the support article and the object remain substantially constant during the examination and treatment to facilitate treating a desired area of the object.
摘要翻译：操作室可以包括用于使用X射线辐射检查物体的物体扫描装置和用于使用粒子辐射处理物体的照射部件。在检查和处理期间物体可以驻留的支撑物品可以被配置为围绕基本上垂直于X射线辐射行进的平面的轴线旋转，可以被配置为相对于轴线倾斜，以及 /或者可以被配置为相对于轴线偏航。以这种方式，在检查和处理期间，支撑制品和物体的相对定向保持基本上恒定，以便于处理物体的期望区域。

13. 发明授权

US08418288B2 Modular patient support system 有权
标题翻译：模块化患者支持系统
公开(公告)号：US08418288B2
公开(公告)日：2013-04-16
申请号：US13345090
申请日：2012-01-06
申请人： Daniel W. Miller , Steve K. McAllaster , Jerry D. Slater , Nickolas S. Rigney , Daniel C. Anderson , Michael F. Moyers
发明人： Daniel W. Miller , Steve K. McAllaster , Jerry D. Slater , Nickolas S. Rigney , Daniel C. Anderson , Michael F. Moyers
IPC分类号： A61G7/07
CPC分类号： A61N5/107 , A61B6/0442 , A61B6/4092 , A61B6/547 , A61B2090/3937 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/1078 , A61N2005/105 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , A61N2005/1097 , B25J9/1666 , G05B15/02 , G05B2219/45117
摘要： A radiation treatment system (100) for accurately delivering radiation to a targeted site within a cancer patient (108) that includes a modular patient support system and a patient positioner (114). The modular patient support system includes a modularly expandable patient pod (200) and at least one immobilization device, such as, for example, a rigid moldable foam cradle (350). The patient pod (200) includes a generally hemi-cylindrical support shell (212) that extends longitudinally between proximal edge (214) and distal edge (216), and transversely between two lateral edges (222, 224). In one embodiment, the lateral edges (222, 224) are tapered to minimize edge effects that result when radiation beams traverse the lateral edges (222, 224).
摘要翻译： 1.一种辐射治疗系统（100），用于将辐射准确地传送到癌症患者（108）内的目标部位，其包括模块化患者支撑系统和患者定位器（114）。模块化患者支撑系统包括模块化可扩展的患者支架（200）和至少一个固定装置，例如刚性可模制泡沫支架（350）。患者荚（200）包括在近端边缘（214）和远端边缘（216）之间纵向延伸且横向于两个横向边缘（222,224）之间延伸的大致半圆柱形的支撑壳体（212）。在一个实施例中，横向边缘（222,224）是锥形的，以最小化当辐射束横穿横向边缘（222,224）时产生的边缘效应。

14. 发明授权

US08378321B2 Charged particle cancer therapy and patient positioning method and apparatus 失效
标题翻译：带电颗粒癌治疗和患者定位方法和装置
公开(公告)号：US08378321B2
公开(公告)日：2013-02-19
申请号：US12554913
申请日：2009-09-06
申请人： Vladimir Balakin
发明人： Vladimir Balakin
IPC分类号： A61N5/10
CPC分类号： H05H13/04 , A61B6/04 , A61B6/4028 , A61B6/4092 , A61N5/1049 , A61N2005/1087 , H05H7/08 , H05H7/12
摘要： The invention comprises a laying, semi-vertical, or seated patient positioning, alignment, and/or control method and apparatus used in conjunction with multi-axis charged particle or proton beam radiation therapy of cancerous tumors. Patient positioning constraints are used to maintain the patient in a treatment position, including one or more of: a seat support, a back support, a head support, an arm support, a knee support, and a foot support. One or more of the positioning constraints are movable and/or under computer control for rapid positioning and/or immobilization of the patient. The system optionally uses an X-ray beam that lies in substantially the same path as a proton beam path of a particle beam cancer therapy system. The generated image is usable for: fine tuning body alignment relative to the proton beam path, to control the proton beam path to accurately and precisely target the tumor, and/or in system verification and validation.
摘要翻译：本发明包括与癌症肿瘤的多轴带电粒子或质子束放射治疗结合使用的铺设，半垂直或就座的患者定位，对准和/或控制方法和装置。患者定位限制用于将患者维持在治疗位置，包括以下中的一个或多个：座椅支撑件，背部支撑件，头部支撑件，手臂支撑件，膝盖支撑件和脚部支撑件。一个或多个定位限制是可移动的和/或在计算机控制下，用于病人的快速定位和/或固定。系统可选地使用位于与粒子束癌治疗系统的质子束路径基本相同的路径中的X射线束。生成的图像可用于：相对于质子束路径精细调整身体对准，以控制质子束路径以准确且精确地靶向肿瘤，和/或在系统验证和验证中。

15. 发明申请

US20120323516A1 PATIENT ALIGNMENT SYSTEM WITH EXTERNAL MEASUREMENT AND OBJECT COORDINATION FOR RADIATION THERAPY SYSTEM 失效
标题翻译：具有外部测量和放射治疗系统对象协调的患者对齐系统
公开(公告)号：US20120323516A1
公开(公告)日：2012-12-20
申请号：US13594630
申请日：2012-08-24
申请人： Nickolas S. Rigney , Daniel C. Anderson , David A. Lesyna , Daniel W. Miller , Michael F. Moyers , Chieh C. Cheng , Michael A. Baumann
发明人： Nickolas S. Rigney , Daniel C. Anderson , David A. Lesyna , Daniel W. Miller , Michael F. Moyers , Chieh C. Cheng , Michael A. Baumann
IPC分类号： G06F15/00 , G01C9/00 , G01N23/04
CPC分类号： A61N5/107 , A61B6/0442 , A61B6/4092 , A61B6/547 , A61B2090/3937 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/1078 , A61N2005/105 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , A61N2005/1097 , B25J9/1666 , G05B15/02 , G05B2219/45117
摘要： A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems.
摘要翻译：用于放射治疗系统的患者对准系统。对准系统包括多个外部测量装置，其获得可移动和/或经受弯曲或其它位置变化的辐射治疗系统的部件的位置测量。对准系统采用外部测量来提供校正定位反馈，以更精确地对准患者并将其与辐射束对准。对准系统可以作为放射治疗系统的组成部分提供，或者可以作为现有放射治疗系统的升级来添加。

16. 发明申请

US20120237104A1 PARTICLE IMAGE VELOCIMETRY SUITABLE FOR X-RAY PROJECTION IMAGING 有权
标题翻译：适用于X射线投影成像的颗粒图像快速计算
公开(公告)号：US20120237104A1
公开(公告)日：2012-09-20
申请号：US13496322
申请日：2010-09-16
申请人： Andreas Fouras , Stephen Dubsky
发明人： Andreas Fouras , Stephen Dubsky
IPC分类号： A61B6/03 , G06K9/00
CPC分类号： A61B6/507 , A61B5/0261 , A61B5/08 , A61B5/087 , A61B6/032 , A61B6/4007 , A61B6/4014 , A61B6/4085 , A61B6/4092 , A61B6/482 , A61B6/484 , A61B6/504 , A61B6/508 , A61B6/5217 , A61B8/06 , A61B8/485 , G01F1/712 , G06T7/20 , G06T2207/10124 , G06T2207/20112 , G06T2207/30061
摘要： A 2D or 3D velocity field is reconstructed from a cross-correlation analysis of image pairs of a sample, without first reconstructing images of the sample spatial structure. The method can be implemented via computer tomographic X-ray particle image velocimetry, using multiple projection angles, with phase contrast images forming dynamic speckle patterns. Estimated cross-correlations may be generated via convolution of a measured autocorrelation function with a velocity probability density function, and the velocity coefficients iteratively optimised to minimise the error between the estimated cross-correlations and the measured cross-correlations. The method may be applied to measure blood flow, and the motion of tissue and organs such as heart and lungs.
摘要翻译：从样本的图像对的互相关分析重建2D或3D速度场，而不首先重建样本空间结构的图像。该方法可以通过使用多个投影角的计算机断层X射线粒子图像测速实现，相位差图像形成动态斑点图案。可以通过测量的自相关函数与速度概率密度函数的卷积以及迭代优化的速度系数来产生估计的交叉相关性，以使估计的交叉相关性与测量的交叉相关之间的误差最小化。该方法可以用于测量血液流动，以及组织和器官如心脏和肺的运动。

17. 发明授权

US08165270B2 X-ray optical grating and method for the production thereof, and X-ray detector embodying same 失效
标题翻译： X射线光栅及其制造方法以及具有该X射线光栅的X射线检测器
公开(公告)号：US08165270B2
公开(公告)日：2012-04-24
申请号：US12566858
申请日：2009-09-25
申请人： Christian David , Tilman Donath , Eckhard Hempel , Martin Hoheisel , Barbara Matthis , Franz Pfeiffer , Stefan Popescu
发明人： Christian David , Tilman Donath , Eckhard Hempel , Martin Hoheisel , Barbara Matthis , Franz Pfeiffer , Stefan Popescu
IPC分类号： G21K1/00
CPC分类号： A61B6/06 , A61B6/03 , A61B6/4092 , A61B6/4291 , A61B6/484 , G01T1/00 , G21K1/025 , G21K1/06 , G21K2207/005 , Y10T29/49
摘要： In a method for the production of x-ray-optical gratings composed of a first material forming of periodically arranged grating webs and grating openings, a second material is applied by electroplating to fill the grid openings. The electroplating is continued until a cohesive layer of the second material with uniform height is created over the grating webs with this layer having a large absorption coefficient, the absorption properties of the grating structure of the grating are homogenized, so an improvement of the measurement signals that are generated with this grating is improved. Moreover, the mechanical stability of gratings produced in such a manner is improved.
摘要翻译：在用于生产由形成周期性布置的光栅幅材和光栅开口的第一材料组成的x射线光栅的方法中，通过电镀施加第二材料以填充栅格开口。电镀继续进行，直到在光栅幅面上形成具有均匀高度的第二材料的内聚层，该层具有大的吸收系数，光栅的光栅结构的吸收特性被均匀化，因此测量信号的改进改善了用该光栅产生的光栅。此外，改善了以这种方式制造的光栅的机械稳定性。

18. 发明授权

US07991454B2 Imaging of biological structures 有权
标题翻译：生物结构成像
公开(公告)号：US07991454B2
公开(公告)日：2011-08-02
申请号：US10435717
申请日：2003-05-08
申请人： Yeu-Kuang Hwu , Giorgio Margaritondo , Jung Ho Je
发明人： Yeu-Kuang Hwu , Giorgio Margaritondo , Jung Ho Je
IPC分类号： A61B6/00
CPC分类号： A61B6/482 , A61B6/4092 , A61B6/481 , A61B6/484 , A61B6/504 , A61B6/508
摘要： Images of blood vessels of a body are obtained by injecting a refraction enhancement contrast agent into the blood vessels to increase a difference in refractive indices of the blood vessels and surrounding material. The blood vessels are irradiated with a penetrating radiation, and an image of the blood vessels is generated based on detected radiation. The image has visible edge enhancement features indicating boundaries of the blood vessels.
摘要翻译：通过将折射增强造影剂注射到血管中以增加血管和周围材料的折射率差异来获得身体血管的图像。用穿透性辐射照射血管，并且基于检测到的辐射产生血管的图像。该图像具有指示血管边界的可见边缘增强特征。

19. 发明授权

US07949096B2 Path planning and collision avoidance for movement of instruments in a radiation therapy environment 有权
标题翻译：放射治疗环境中仪器运动的路径规划和避免碰撞
公开(公告)号：US07949096B2
公开(公告)日：2011-05-24
申请号：US12825076
申请日：2010-06-28
申请人： Chieh C. Cheng , David A. Lesyna , Michael F. Moyers
发明人： Chieh C. Cheng , David A. Lesyna , Michael F. Moyers
IPC分类号： A61N5/10
CPC分类号： A61N5/107 , A61B6/0442 , A61B6/4092 , A61B6/547 , A61B2090/3937 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/1078 , A61N2005/105 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , A61N2005/1097 , B25J9/1666 , G05B15/02 , G05B2219/45117
摘要： A patient positioning system for use with a radiation therapy system that monitors the location of fixed and movable components and pre-plans movement of the movable components so as to inhibit movement if a collision would be indicated. The positioning system can also coordinate movement of multiple movable components for reduced overall latency in registering a patient. The positioning system includes external measurement devices which measure the location and orientation of objects, including components of the radiation therapy system, in space and can also monitor for intrusion into the active area of the therapy system by personnel or foreign objects to improve operational safety of the radiation therapy system.
摘要翻译：一种与放射治疗系统一起使用的患者定位系统，其监测固定和可移动部件的位置，并预先计划可移动部件的移动，以便在指示碰撞时抑制运动。定位系统还可以协调多个可移动部件的移动，以减少注册患者时的整体延迟。定位系统包括外部测量装置，其测量物体的位置和方向，包括放射治疗系统的部件，在空间中，并且还可以监视人员或异物侵入治疗系统的有效区域以提高操作安全性放射治疗系统。

20. 发明申请

US20110051891A1 COMPUTED TOMOGRAPHY EXAMINATION AND PARTICLE THERAPY TREATMENT 失效
标题翻译：计算机血管造影检查和颗粒治疗
公开(公告)号：US20110051891A1
公开(公告)日：2011-03-03
申请号：US12551024
申请日：2009-08-31
申请人： John P. O'Connor , Charles Shaughnessy
发明人： John P. O'Connor , Charles Shaughnessy
IPC分类号： A61N5/10 , G21K5/00 , G21K5/10 , A61B6/03
CPC分类号： A61B6/04 , A61B6/0478 , A61B6/12 , A61B6/4092 , A61B6/4429 , A61B6/547 , A61N5/1049 , A61N5/1078 , A61N2005/1061 , A61N2005/1063 , A61N2005/1087
摘要： An operation room may comprise both an object scanning apparatus for examining an object using x-ray radiation and an irradiation component for treating an object using particle radiation. A support article upon which the object may reside during (both) the examination and treatment may be configured to rotate about an axis substantially perpendicular to a plane through which x-ray radiation travels, may be configured to tilt with respect to the axis, and/or may be configured to yaw with respect to the axis. In this way, the relative orientation of the support article and the object remain substantially constant during the examination and treatment to facilitate treating a desired area of the object.
摘要翻译：操作室可以包括用于使用X射线辐射检查物体的物体扫描装置和用于使用粒子辐射处理物体的照射部件。在检查和处理期间物体可以驻留的支撑物品可以被配置为围绕基本上垂直于X射线辐射行进的平面的轴线旋转，可以被配置为相对于轴线倾斜，以及 /或者可以被配置为相对于轴线偏航。以这种方式，在检查和处理期间，支撑制品和物体的相对定向保持基本上恒定，以便于处理物体的期望区域。

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